Result of FASTA (omim) for
pF1KB8665
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8665, 499 aa
1>>>pF1KB8665 499 - 499 aa - 499 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3409+/-0.000346; mu= 20.1030+/- 0.022
mean_var=93.3721+/-18.440, 0's: 0 Z-trim(115.8): 15 B-trim: 156 in 1/59
Lambda= 0.132729
statistics sampled from 26422 (26436) to 26422 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.31), width: 16
Scan time: 10.520
The best scores are: opt bits E(85289)
XP_006723200 (OMIM: 600138,606419) PREDICTED: U4/U ( 499) 3156 614.6 2.1e-175
NP_056444 (OMIM: 600138,606419) U4/U6 small nuclea ( 499) 3156 614.6 2.1e-175
NP_057018 (OMIM: 616742) nucleolar protein 58 [Hom ( 529) 427 92.0 4.4e-18
NP_006383 (OMIM: 614153,614154) nucleolar protein ( 594) 399 86.7 2e-16
>>XP_006723200 (OMIM: 600138,606419) PREDICTED: U4/U6 sm (499 aa)
initn: 3156 init1: 3156 opt: 3156 Z-score: 3270.1 bits: 614.6 E(85289): 2.1e-175
Smith-Waterman score: 3156; 99.8% identity (100.0% similar) in 499 aa overlap (1-499:1-499)
10 20 30 40 50 60
pF1KB8 MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LSKVPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCT
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 KMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
430 440 450 460 470 480
490
pF1KB8 SSMAEFLKVKGEKSGLMST
:::::::::::::::::::
XP_006 SSMAEFLKVKGEKSGLMST
490
>>NP_056444 (OMIM: 600138,606419) U4/U6 small nuclear ri (499 aa)
initn: 3156 init1: 3156 opt: 3156 Z-score: 3270.1 bits: 614.6 E(85289): 2.1e-175
Smith-Waterman score: 3156; 99.8% identity (100.0% similar) in 499 aa overlap (1-499:1-499)
10 20 30 40 50 60
pF1KB8 MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MSLADELLADLEEAAEEEEGGSYGEEEEEPAIEDVQEETQLDLSGDSVKTIAKLWDSKMF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 AEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AEIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RFPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LSKVPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCT
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LSKMPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LAARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 KMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
430 440 450 460 470 480
490
pF1KB8 SSMAEFLKVKGEKSGLMST
:::::::::::::::::::
NP_056 SSMAEFLKVKGEKSGLMST
490
>>NP_057018 (OMIM: 616742) nucleolar protein 58 [Homo sa (529 aa)
initn: 402 init1: 324 opt: 427 Z-score: 445.6 bits: 92.0 E(85289): 4.4e-18
Smith-Waterman score: 437; 23.6% identity (61.2% similar) in 381 aa overlap (92-471:161-521)
70 80 90 100 110 120
pF1KB8 EIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKR
.::.: .: ....::: :. :. .
NP_057 EPREMAAMCLGLAHSLSRYRLKFSADKVDTMIVQAISLLDDLDKELNNYIMRCREWYGWH
140 150 160 170 180 190
130 140 150 160 170 180
pF1KB8 FPELESLVPNALDYIRTVKELGNSLDKCKNNENLQQILTNATIMVVSVTASTTQGQQLSE
:::: ... . : : . ....:. : . .:...: . . :...: ..: ..::
NP_057 FPELGKIISDNLTYCKCLQKVGDR--KNYASAKLSELLPEEVEAEVKAAAEISMGTEVSE
200 210 220 230 240
190 200 210 220 230 240
pF1KB8 EELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLTNL
:.. . . : ...:.. . ..:::...:: ::::.....: ..:.... ::.: ::
NP_057 EDICNILHLCTQVIEISEYRTQLYEYLQNRMMAIAPNVTVMVGELVGARLIAHAGSLLNL
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB8 SKVPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKCTL
.: : ....:::.. . ...: :. : :::...: . : . : .:..::: .:
NP_057 AKHAASTVQILGAEKALFRALKSRRDTPKYGLIYHASLVGQTSPKHKGKISRMLAAKTVL
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB8 AARVDSFHESTEGKVGYELKDEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYRK
: : :.: :.. . .: : . ..: .. . : ..... : .. .: . :
NP_057 AIRYDAFGEDSSSAMGVENRAKLEARL-RTLEDRGIRKISGTGKAL-AKTEKYEHKSEVK
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB8 MKERLGLTEIRKQANRMSFGEIE-EDAYQEDLGFSLGHLGKSGSGRVRQTQVNEATKARI
. : . . ... .. ... :: : :. ..... ..:.: . ..
NP_057 TYDPSGDSTLPTCSKKRKIEQVDKEDEITEK---------KAKKAKIK-VKVEEEEEEKV
430 440 450 460 470
430 440 450 460 470 480
pF1KB8 SKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAAEKKVAEANQKYF
.. . ...:.. : :. :... . : . :..:. .::
NP_057 AEEEETSVKKKKK-RGKKKHIKEEPLSEEE-----PCTSTAIASPEKKKKKKKKRENED
480 490 500 510 520
490
pF1KB8 SSMAEFLKVKGEKSGLMST
>>NP_006383 (OMIM: 614153,614154) nucleolar protein 56 [ (594 aa)
initn: 388 init1: 295 opt: 399 Z-score: 415.9 bits: 86.7 E(85289): 2e-16
Smith-Waterman score: 410; 24.7% identity (63.0% similar) in 308 aa overlap (92-386:167-474)
70 80 90 100 110 120
pF1KB8 EIMMKIEEYISKQAKASEVMGPVEAAPEYRVIVDANNLTVEIENELNIIHKFIRDKYSKR
.:... .: ......: . .:. :. .
NP_006 TDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYH
140 150 160 170 180 190
130 140 150 160 170
pF1KB8 FPELESLVPNALDYIRTVKELGNSLDKCKNN-ENLQQILTNATIMVVSVTAS-TTQGQQL
:::: ... . : : .. .:: . ... :.:... ... . . :: ...:...
NP_006 FPELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAKAKAILDASRSSMGMDI
200 210 220 230 240 250
180 190 200 210 220 230
pF1KB8 SEEELERLEEACDMALELNASKHRIYEYVESRMSFIAPNLSIIIGASTAAKIMGVAGGLT
: .: .: . .. :. .. .. :..:.:: .::.:: .:: ...:.... ::.::
NP_006 SAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLT
260 270 280 290 300 310
240 250 260 270 280 290
pF1KB8 NLSKVPACNIMLLGAQRKTLSGFSSTSVLPHTGYIYHSDIVQSLPPDLRRKAARLVAAKC
::.: :: ....:::.. . .... . :. : :.:: .. . . .: .: ::
NP_006 NLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKC
320 330 340 350 360 370
300 310 320 330 340
pF1KB8 TLAARVDSFHESTEGKVGYELKDEIERKFDKWQ--EPP---------PVKQVKPLPAPLD
..:.:.: : : . : .:....:.... .. : : . :.. : .
NP_006 SIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEIT
380 390 400 410 420 430
350 360 370 380 390 400
pF1KB8 GQRKKRGGRRYRKMKERLGLTEIRKQANRMSFGEIEEDAYQEDLGFSLGHLGKSGSGRVR
. .:. .: .: :.::. . .. : : : :.
NP_006 RKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGM
440 450 460 470 480 490
410 420 430 440 450 460
pF1KB8 QTQVNEATKARISKTLQRTLQKQSVVYGGKSTIRDRSSGTASSVAFTPLQGLEIVNPQAA
NP_006 EDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEETVNDPEEAGHRSGS
500 510 520 530 540 550
499 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:21:21 2016 done: Fri Nov 4 14:21:22 2016
Total Scan time: 10.520 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]