Result of FASTA (ccds) for
pF1KB8647
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8647, 824 aa
1>>>pF1KB8647 824 - 824 aa - 824 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1747+/-0.00127; mu= 17.0805+/- 0.075
mean_var=160.3741+/-31.124, 0's: 0 Z-trim(107.2): 215 B-trim: 16 in 1/50
Lambda= 0.101276
statistics sampled from 9192 (9445) to 9192 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.29), width: 16
Scan time: 2.740
The best scores are: opt bits E(32554)
CCDS74857.1 TMPRSS6 gene_id:164656|Hs108|chr22 ( 824) 5785 858.7 0
CCDS74856.1 TMPRSS6 gene_id:164656|Hs108|chr22 ( 802) 4926 733.2 4.2e-211
CCDS13941.1 TMPRSS6 gene_id:164656|Hs108|chr22 ( 811) 4926 733.2 4.3e-211
CCDS43129.2 TMPRSS7 gene_id:344805|Hs108|chr3 ( 717) 1051 166.9 1.1e-40
CCDS33908.1 MASP1 gene_id:5648|Hs108|chr3 ( 728) 496 85.8 2.8e-16
CCDS42110.1 PRSS33 gene_id:260429|Hs108|chr16 ( 280) 486 83.9 4.3e-16
CCDS58452.1 PRSS36 gene_id:146547|Hs108|chr16 ( 752) 470 82.1 4e-15
CCDS58453.1 PRSS36 gene_id:146547|Hs108|chr16 ( 850) 470 82.1 4.3e-15
CCDS32436.1 PRSS36 gene_id:146547|Hs108|chr16 ( 855) 470 82.1 4.3e-15
CCDS73391.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 413) 452 79.1 1.7e-14
CCDS73392.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 448) 452 79.2 1.8e-14
CCDS44735.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 457) 452 79.2 1.8e-14
CCDS10476.1 PRSS27 gene_id:83886|Hs108|chr16 ( 290) 437 76.7 6.2e-14
CCDS31476.1 F2 gene_id:2147|Hs108|chr11 ( 622) 434 76.7 1.4e-13
CCDS33564.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 492) 428 75.7 2.2e-13
CCDS54486.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 529) 428 75.7 2.3e-13
CCDS10481.1 PRSS22 gene_id:64063|Hs108|chr16 ( 317) 422 74.6 3e-13
CCDS45469.1 PRSS8 gene_id:5652|Hs108|chr16 ( 343) 420 74.3 3.9e-13
CCDS55788.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 532) 409 73.0 1.6e-12
CCDS13686.1 TMPRSS3 gene_id:64699|Hs108|chr21 ( 454) 408 72.7 1.6e-12
CCDS58185.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 563) 409 73.0 1.6e-12
CCDS41721.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 567) 409 73.0 1.6e-12
CCDS42153.1 PRSS53 gene_id:339105|Hs108|chr16 ( 553) 408 72.8 1.8e-12
CCDS10430.1 TPSG1 gene_id:25823|Hs108|chr16 ( 321) 401 71.5 2.5e-12
CCDS47145.1 PRSS48 gene_id:345062|Hs108|chr4 ( 328) 399 71.2 3.2e-12
CCDS58790.1 TMPRSS3 gene_id:64699|Hs108|chr21 ( 453) 400 71.6 3.5e-12
CCDS45388.1 PRSS21 gene_id:10942|Hs108|chr16 ( 300) 396 70.8 4e-12
CCDS10478.1 PRSS21 gene_id:10942|Hs108|chr16 ( 314) 396 70.8 4.2e-12
CCDS32993.1 HPN gene_id:3249|Hs108|chr19 ( 417) 396 70.9 5e-12
CCDS74669.1 PRSS56 gene_id:646960|Hs108|chr2 ( 603) 398 71.4 5.1e-12
CCDS82982.1 KLKB1 gene_id:3818|Hs108|chr4 ( 514) 397 71.2 5.1e-12
CCDS54297.1 KLK11 gene_id:11012|Hs108|chr19 ( 275) 389 69.7 7.8e-12
CCDS46816.1 PRSS42 gene_id:339906|Hs108|chr3 ( 293) 386 69.3 1.1e-11
CCDS44881.1 TMPRSS12 gene_id:283471|Hs108|chr12 ( 348) 386 69.4 1.2e-11
CCDS44743.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 432) 378 68.3 3.1e-11
CCDS13571.1 TMPRSS15 gene_id:5651|Hs108|chr21 (1019) 380 69.1 4.4e-11
CCDS12088.1 TMPRSS9 gene_id:360200|Hs108|chr19 (1059) 380 69.1 4.5e-11
CCDS76482.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 290) 366 66.3 8.3e-11
>>CCDS74857.1 TMPRSS6 gene_id:164656|Hs108|chr22 (824 aa)
initn: 5785 init1: 5785 opt: 5785 Z-score: 4581.5 bits: 858.7 E(32554): 0
Smith-Waterman score: 5785; 100.0% identity (100.0% similar) in 824 aa overlap (1-824:1-824)
10 20 30 40 50 60
pF1KB8 MPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLLALLVLASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLLALLVLASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 VLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELLSTVNSSAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 RLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELLSTVNSSAAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDHLASSCLWHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDHLASSCLWHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 QGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVEVLASGAIMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 QGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVEVLASGAIMA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 VVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 ITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 ITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 VCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 VCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 QCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 QCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIAD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 RWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 ALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRADAVALFYGWRNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 ALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRADAVALFYGWRNQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 GSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 GSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLV
730 740 750 760 770 780
790 800 810 820
pF1KB8 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
::::::::::::::::::::::::::::::::::::::::::::
CCDS74 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
790 800 810 820
>>CCDS74856.1 TMPRSS6 gene_id:164656|Hs108|chr22 (802 aa)
initn: 4926 init1: 4926 opt: 4926 Z-score: 3903.4 bits: 733.2 E(32554): 4.2e-211
Smith-Waterman score: 5558; 97.2% identity (97.3% similar) in 824 aa overlap (1-824:1-802)
10 20 30 40 50 60
pF1KB8 MPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLLALLVLASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLLALLVLASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 VLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELLSTVNSSAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 RLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELLSTVNSSAAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDHLASSCLWHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 PYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDHLASSCLWHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 QGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVEVLASGAIMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 QGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVEVLASGAIMA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 VVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 ITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 ITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 VCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 VCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 QCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 QCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIAD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 RWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 ALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRADAVALFYGWRNQ
::::::::::::::::::::::::::::::::::::::::::::.
CCDS74 ALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGG---------------
670 680 690 700
730 740 750 760 770 780
pF1KB8 GSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 -------PISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLV
710 720 730 740 750
790 800 810 820
pF1KB8 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
::::::::::::::::::::::::::::::::::::::::::::
CCDS74 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
760 770 780 790 800
>>CCDS13941.1 TMPRSS6 gene_id:164656|Hs108|chr22 (811 aa)
initn: 4926 init1: 4926 opt: 4926 Z-score: 3903.3 bits: 733.2 E(32554): 4.3e-211
Smith-Waterman score: 5558; 97.2% identity (97.3% similar) in 824 aa overlap (1-824:10-811)
10 20 30 40 50
pF1KB8 MPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLL
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MLLLFHSKRMPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 ALLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 ALLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 MLKELITSTRLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MLKELITSTRLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 STVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 STVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDH
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 LASSCLWHLQGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LASSCLWHLQGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 VLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYY
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 SPQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SPQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 RIPVVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RIPVVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDC
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 PNGLDERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PNGLDERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCED
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 RSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRH
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 ICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 ICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYH
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 EEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRADAV
:::::::::::::::::::::::::::::::::::::::::::::::::::::.
CCDS13 EEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGG------
670 680 690 700 710
720 730 740 750 760 770
pF1KB8 ALFYGWRNQGSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDAC
::::::::::::::::::::::::::::::::::::::::::::
CCDS13 ----------------PISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDAC
720 730 740 750
780 790 800 810 820
pF1KB8 QGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
760 770 780 790 800 810
>>CCDS43129.2 TMPRSS7 gene_id:344805|Hs108|chr3 (717 aa)
initn: 719 init1: 295 opt: 1051 Z-score: 844.0 bits: 166.9 E(32554): 1.1e-40
Smith-Waterman score: 1451; 32.8% identity (60.5% similar) in 769 aa overlap (83-823:2-713)
60 70 80 90 100 110
pF1KB8 LLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKM
.:. : .: . ..:: : : . .:..
CCDS43 MFRITNIEFLPEYRQKESREFLSVSRTVQQV
10 20 30
120 130 140 150 160 170
pF1KB8 LKELITSTRLGTYYNSSSV--YSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEEL
.. . :.. .. .:..: : : ..: : ::... .:. . .. . : :.: . .
CCDS43 INLVYTTSAFSKFYEQSVVADVSNNKGGLLVHFWIVFVMPRAKGHIFCEDCVAAILKDSI
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB8 LSTVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPD
... . ..: . .::.. :: .::. :: .: :. . : :. :
CCDS43 QTSIINRTSVG-------SLQGLAVDMDSV----VLNDK-GCSQYFYAEH---LSLHYPL
100 110 120 130
240 250 260 270 280
pF1KB8 HLASS-----CLWHLQGPKDLMLKLRLEWTLAE---C-RDRLAMYDVAGPLEKRLITSVY
..... : ..: . ...: .. : : : :..:: :... .. .
CCDS43 EISAASGRLMCHFKLVAIVGYLIRLSIKSIQIEADNCVTDSLTIYDSLLPIRSSILYRI-
140 150 160 170 180 190
290 300 310 320 330
pF1KB8 GCSRQEPVVEVLASGAIMAVVWKK-------GLHSYYDPFVLSVQPVVFQACEVNLTLDN
: . .. .... .: :..:. :...:.. : : : :: .. . .
CCDS43 -CEPTRTLMSFVSTNNLMLVTFKSPHIRRLSGIRAYFE-----VIP--EQKCENTVLVKD
200 210 220 230 240
340 350 360 370 380 390
pF1KB8 RLDSQGVLSTPYFPSYYSPQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWT
.: .:.::.:::: :. .:.:.. . :.:: : :.. .... : .: :
CCDS43 ITGFEGKISSPYYPSYYPPKCKCTWKFQTSLSTLGIALKFYNYSITKKSMK-GCEHGWWE
250 260 270 280 290 300
400 410 420 430 440 450
pF1KB8 IQNRRLCGLRILQPYAERIPVVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCP-GEF
:... :: . . :.: . . :.. . :. . ..:: :: :.::: : :
CCDS43 INEHMYCGSYMDHQTIFRVP---SPLVHIQLQCSSRLSDKPLLAEYGSYNISQPCPVGSF
310 320 330 340 350 360
460 470 480 490 500 510
pF1KB8 LCSVNGLCVPA---CDGVKDCPNGLDERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNG
:: .::::: ::::.:: . :: :: :. .: : .::: :: ::
CCDS43 RCS-SGLCVPQAQRCDGVNDCFDESDELFCVSPQP-ACNTSSFRQHGPLICDGFRDCENG
370 380 390 400 410 420
520 530 540 550 560
pF1KB8 SDEEQCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPS-SRIV
::..: ...::.. ::.: . : .: : .::: :: :::::: : :. .. . ::.
CCDS43 RDEQNCTQSIPCNNRTFKCGNDICFRKQNAKCDGTVDCPDGSDEEGCTCSRSSSALHRII
430 440 450 460 470 480
570 580 590 600 610 620
pF1KB8 GGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVW
::. . :: ::::.::. : ::...:. .:...:::::. . ... . ::. ::
CCDS43 GGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYV
490 500 510 520 530 540
630 640 650 660 670 680
pF1KB8 QNSRWPGEVSF--KVSRLLLHPYHEEDSHDYDVALLQLD--HPVVRSAAVRPVCLPARSH
: :...: : :...: :.. .. :::.:::::. : . . ..:.:.: ..
CCDS43 Q-----GNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIPPTGQ
550 560 570 580 590
690 700 710 720 730 740
pF1KB8 FFEPGLHCWITGWGALREGALRADAVALFYGWRNQGSETCCCPISNALQKVDVQLIPQDL
. : .::.:::: .: :: :.:: . ::...:.:: : :
CCDS43 RVRSGEKCWVTGWGRRHE----AD---------NKGSLV--------LQQAEVELIDQTL
600 610 620 630
750 760 770 780 790 800
pF1KB8 CSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALS-GRWFLAGLVSWGLGCGRPN
: .: .: :::::: .::.:::.::::::: :. : :.:.:.:.:::: : ::::
CCDS43 CVSTYGI-ITSRMLCAGIMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPN
640 650 660 670 680 690
810 820
pF1KB8 YFGVYTRITGVISWIQQVVT
. :::::... . ::.. :
CCDS43 FPGVYTRVSNFVPWIHKYVPSLL
700 710
>>CCDS33908.1 MASP1 gene_id:5648|Hs108|chr3 (728 aa)
initn: 429 init1: 131 opt: 496 Z-score: 405.7 bits: 85.8 E(32554): 2.8e-16
Smith-Waterman score: 574; 28.0% identity (53.2% similar) in 560 aa overlap (324-821:179-713)
300 310 320 330 340 350
pF1KB8 ASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQ-GVLSTPYFPSYYS
..:.:. . :: . .. ::...: ::. :
CCDS33 EELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECS-DNLFTQRTGVITSPDFPNPYP
150 160 170 180 190 200
360 370 380 390 400 410
pF1KB8 PQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPY-AE
...: . . . . . : :. ... ..:: :. : ..: :. .:
CCDS33 KSSECLYTIELEE-GFMVNLQFEDIFDIEDHPEVPCPYDYIKIK----VGPKVLGPFCGE
210 220 230 240 250 260
420 430 440 450 460
pF1KB8 RIP---VVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVP--ACD
. : . . .. : : :. : . : :. : .. :: :. :.: : :
CCDS33 KAPEPISTQSHSVLILFHSDNSGENRGWRLSY--RAAGNECP-ELQPPVHGKIEPSQAKY
270 280 290 300 310
470 480 490 500 510
pF1KB8 GVKD-----CPNGLDE-RNCVCRATFQ--CKEDSTCISLPKVCDGQPDCLNGSDEEQ--C
:: : .: .. : ::: : .:.: . .: :: .. :.
CCDS33 FFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCK-IVDCRAPGELEHGLI
320 330 340 350 360 370
520 530 540 550 560
pF1KB8 QEGVPCGTFTFQCEDRSCVKKPNPQC----DGRPDCRD---------GSDEEHC--DCGL
.. . :.. : . ..: . : : : . : .::
CCDS33 TFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPECGQ
380 390 400 410 420 430
570 580 590 600
pF1KB8 QG---PS--SRIVGGAVSSEGEWPWQASLQVRG-------RHICGGALIADRWVITAAHC
. :: .::.:: . : .:::: . :. . . .:::.. :..::::
CCDS33 PSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHV
440 450 460 470 480 490
610 620 630 640 650 660
pF1KB8 FQEDSMASTVL------WTVFLGKVWQNSR-WPGEVSFKVSRLLLHPYHEEDSHDYDVAL
.. . .::. ::.:: .. : : :. ...:..::: . .....:.::
CCDS33 LRSQRRDTTVIPVSKEHVTVYLG--LHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIAL
500 510 520 530 540 550
670 680 690 700 710 720
pF1KB8 LQLDHPVVRSAAVRPVCLPARSHFFEPGLHCW--ITGWGALREGALRADAVALFYGWRNQ
.::..:: . : ::::: : . :. : ..::: . . . .: . ..
CCDS33 VQLQEPVPLGPHVMPVCLP-RLEPEGPAPHMLGLVAGWG-ISNPNVTVDEII------SS
560 570 580 590 600
730 740 750 760 770
pF1KB8 GSETCCCPISNALQKVDVQLIPQDLCSEVYR-----YQVTPRMLCAGYRKGKKDACQGDS
:..: .:..:: : . ..:. :. :. :.:: :.:::: .: ::.: :::
CCDS33 GTRT----LSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDS
610 620 630 640 650 660
780 790 800 810 820
pF1KB8 GGPLVC-KALSGRWFLAGLVSWGLG---CGRPNYFGVYTRITGVISWIQQVVT
:: .: :: :: . :::::: : :: . .::::.... ..:. .
CCDS33 GGAFVIFDDLSQRWVVQGLVSWG-GPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVVE
670 680 690 700 710 720
CCDS33 PQVER
>>CCDS42110.1 PRSS33 gene_id:260429|Hs108|chr16 (280 aa)
initn: 777 init1: 267 opt: 486 Z-score: 402.5 bits: 83.9 E(32554): 4.3e-16
Smith-Waterman score: 742; 47.0% identity (63.9% similar) in 266 aa overlap (559-824:28-279)
530 540 550 560 570 580
pF1KB8 CEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVR
:: ::::::: . .::::::::.: :
CCDS42 MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHR
10 20 30 40 50
590 600 610 620 630 640
pF1KB8 GRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLH
: :.:::.::: .::.:::::: . .. . . : :: . .: : .: : :.::
CCDS42 GAHVCGGSLIAPQWVLTAAHCFPRRALPAE--YRVRLGALRLGSTSPRTLSVPVRRVLLP
60 70 80 90 100 110
650 660 670 680 690 700
pF1KB8 PYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRA
: . ::. :.::::: .:: :: :.:::::. . :: : .::::.:: :.
CCDS42 PDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLP
120 130 140 150 160 170
710 720 730 740 750 760
pF1KB8 DAVALFYGWRNQGSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKK
. : : : .. : ..: .: .. .:: . : : : ::::: .:.:
CCDS42 EWRPL-QGVRVPLLDSRTC---DGLYHVGAD-VPQ-----AERI-VLPGSLCAGYPQGHK
180 190 200 210 220
770 780 790 800 810 820
pF1KB8 DACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
:::::::::::.: :: : :.:.:::: ::. :: :::: .. ::: :.
CCDS42 DACQGDSGGPLTCLQ-SGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF
230 240 250 260 270 280
>>CCDS58452.1 PRSS36 gene_id:146547|Hs108|chr16 (752 aa)
initn: 689 init1: 256 opt: 470 Z-score: 385.0 bits: 82.1 E(32554): 4e-15
Smith-Waterman score: 720; 41.1% identity (62.5% similar) in 280 aa overlap (553-823:32-290)
530 540 550 560 570 580
pF1KB8 GTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQ
. : ::: ::.:::::. .. : ::::
CCDS58 ARHLLLPLVMLVISPIPGAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQ
10 20 30 40 50 60
590 600 610 620 630 640
pF1KB8 ASLQVRGRHICGGALIADRWVITAAHCFQED-SMASTVLWTVFLGKVWQNSRWPGEVSFK
.::. : :::::.::: ::..:::::. . .. .. :.:.:: :.. : .
CCDS58 VSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRA
70 80 90 100 110 120
650 660 670 680 690 700
pF1KB8 VSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGAL
:. ... . . :.:::.: :. . :: ::::: :: : : :: :::: .
CCDS58 VAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDV
130 140 150 160 170 180
710 720 730 740 750
pF1KB8 REGALRADAVALFYGWRNQGSETCCCPISNALQKVDVQLIPQDLCSEVYRY--------Q
.: :: . : : .::.:...:. . :. .: :
CCDS58 QE----ADPLPL--PW--------------VLQEVELRLLGEATCQCLYSQPGPFNLTLQ
190 200 210 220
760 770 780 790 800 810
pF1KB8 VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRIT
. : :::::: .:..:.:::::::::::. .:::: ::..:.:.:::: : ::.: ..
CCDS58 ILPGMLCAGYPEGRRDTCQGDSGGPLVCEE-GGRWFQAGITSFGFGCGRRNRPGVFTAVA
230 240 250 260 270 280
820
pF1KB8 GVISWIQQVVT
.::.. :
CCDS58 TYEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQV
290 300 310 320 330 340
>>CCDS58453.1 PRSS36 gene_id:146547|Hs108|chr16 (850 aa)
initn: 689 init1: 256 opt: 470 Z-score: 384.4 bits: 82.1 E(32554): 4.3e-15
Smith-Waterman score: 720; 41.1% identity (62.5% similar) in 280 aa overlap (553-823:32-290)
530 540 550 560 570 580
pF1KB8 GTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQ
. : ::: ::.:::::. .. : ::::
CCDS58 ARHLLLPLVMLVISPIPGAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQ
10 20 30 40 50 60
590 600 610 620 630 640
pF1KB8 ASLQVRGRHICGGALIADRWVITAAHCFQED-SMASTVLWTVFLGKVWQNSRWPGEVSFK
.::. : :::::.::: ::..:::::. . .. .. :.:.:: :.. : .
CCDS58 VSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRA
70 80 90 100 110 120
650 660 670 680 690 700
pF1KB8 VSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGAL
:. ... . . :.:::.: :. . :: ::::: :: : : :: :::: .
CCDS58 VAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDV
130 140 150 160 170 180
710 720 730 740 750
pF1KB8 REGALRADAVALFYGWRNQGSETCCCPISNALQKVDVQLIPQDLCSEVYRY--------Q
.: :: . : : .::.:...:. . :. .: :
CCDS58 QE----ADPLPL--PW--------------VLQEVELRLLGEATCQCLYSQPGPFNLTLQ
190 200 210 220
760 770 780 790 800 810
pF1KB8 VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRIT
. : :::::: .:..:.:::::::::::. .:::: ::..:.:.:::: : ::.: ..
CCDS58 ILPGMLCAGYPEGRRDTCQGDSGGPLVCEE-GGRWFQAGITSFGFGCGRRNRPGVFTAVA
230 240 250 260 270 280
820
pF1KB8 GVISWIQQVVT
.::.. :
CCDS58 TYEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQV
290 300 310 320 330 340
>>CCDS32436.1 PRSS36 gene_id:146547|Hs108|chr16 (855 aa)
initn: 689 init1: 256 opt: 470 Z-score: 384.4 bits: 82.1 E(32554): 4.3e-15
Smith-Waterman score: 720; 41.1% identity (62.5% similar) in 280 aa overlap (553-823:32-290)
530 540 550 560 570 580
pF1KB8 GTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQ
. : ::: ::.:::::. .. : ::::
CCDS32 ARHLLLPLVMLVISPIPGAFQDSALSPTQEEPEDLDCGRPEPSARIVGGSNAQPGTWPWQ
10 20 30 40 50 60
590 600 610 620 630 640
pF1KB8 ASLQVRGRHICGGALIADRWVITAAHCFQED-SMASTVLWTVFLGKVWQNSRWPGEVSFK
.::. : :::::.::: ::..:::::. . .. .. :.:.:: :.. : .
CCDS32 VSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRA
70 80 90 100 110 120
650 660 670 680 690 700
pF1KB8 VSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGAL
:. ... . . :.:::.: :. . :: ::::: :: : : :: :::: .
CCDS32 VAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDV
130 140 150 160 170 180
710 720 730 740 750
pF1KB8 REGALRADAVALFYGWRNQGSETCCCPISNALQKVDVQLIPQDLCSEVYRY--------Q
.: :: . : : .::.:...:. . :. .: :
CCDS32 QE----ADPLPL--PW--------------VLQEVELRLLGEATCQCLYSQPGPFNLTLQ
190 200 210 220
760 770 780 790 800 810
pF1KB8 VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRIT
. : :::::: .:..:.:::::::::::. .:::: ::..:.:.:::: : ::.: ..
CCDS32 ILPGMLCAGYPEGRRDTCQGDSGGPLVCEE-GGRWFQAGITSFGFGCGRRNRPGVFTAVA
230 240 250 260 270 280
820
pF1KB8 GVISWIQQVVT
.::.. :
CCDS32 TYEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWPWEAQV
290 300 310 320 330 340
>>CCDS73391.1 TMPRSS5 gene_id:80975|Hs108|chr11 (413 aa)
initn: 744 init1: 255 opt: 452 Z-score: 373.7 bits: 79.1 E(32554): 1.7e-14
Smith-Waterman score: 729; 41.8% identity (63.6% similar) in 280 aa overlap (545-820:149-405)
520 530 540 550 560 570
pF1KB8 QCQEGVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEE-HC-DCGLQGPSSRIVGGA
: .: .:. .: .:: . .::::::
CCDS73 NLTDIKLNSSQEFAQLSPRLGGFLEEAWQPRNNCTSGQVVSLRCSECGARPLASRIVGGQ
120 130 140 150 160 170
580 590 600 610 620 630
pF1KB8 VSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNS
. :.::::::. . :: :::...: :::.:::::.. .: : : : : ...
CCDS73 SVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHSA
180 190 200 210 220 230
640 650 660 670 680 690
pF1KB8 RWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLH
: . .. : :.. :: . ..::::::::.:. . : .: :::::. . : : .
CCDS73 VRPHQGAL-VERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSR
240 250 260 270 280 290
700 710 720 730 740 750
pF1KB8 CWITGWGALREGALRADAVALFYGWRNQGSETCCCPISNALQKVDVQLIPQDLC--SEVY
::..::: ... :.: :. :: . : :. .:: : ::
CCDS73 CWVSGWG------------------HTHPSHTYS---SDMLQDTVVPLFSTQLCNSSCVY
300 310 320 330
760 770 780 790 800 810
pF1KB8 RYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYT
.::::::::: :. ::::::::::::: . : :.:.:::: ::..::. :::.
CCDS73 SGALTPRMLCAGYLDGRADACQGDSGGPLVCPD-GDTWRLVGVVSWGRGCAEPNHPGVYA
340 350 360 370 380 390
820
pF1KB8 RITGVISWIQQVVT
... ..::.
CCDS73 KVAEFLDWIHDTAQDSLL
400 410
824 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:17:10 2016 done: Sat Nov 5 22:17:10 2016
Total Scan time: 2.740 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]