Result of FASTA (omim) for
pF1KB8595
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8595, 2202 aa
1>>>pF1KB8595 2202 - 2202 aa - 2202 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0085+/-0.000601; mu= 15.6985+/- 0.037
mean_var=86.4487+/-17.293, 0's: 0 Z-trim(104.6): 109 B-trim: 0 in 0/56
Lambda= 0.137942
statistics sampled from 12813 (12922) to 12813 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.461), E-opt: 0.2 (0.152), width: 16
Scan time: 18.380
The best scores are: opt bits E(85289)
NP_006819 (OMIM: 614217) activating signal cointeg (2202) 14512 2899.9 0
XP_011533696 (OMIM: 614217) PREDICTED: activating (2207) 14492 2895.9 0
XP_011533698 (OMIM: 614217) PREDICTED: activating (2104) 13897 2777.5 0
XP_016865694 (OMIM: 614217) PREDICTED: activating (2104) 13897 2777.5 0
XP_011533697 (OMIM: 614217) PREDICTED: activating (2104) 13897 2777.5 0
XP_016865695 (OMIM: 614217) PREDICTED: activating (1729) 11426 2285.8 0
NP_054733 (OMIM: 601664,610359) U5 small nuclear r (2136) 5023 1011.5 0
XP_016859092 (OMIM: 601664,610359) PREDICTED: U5 s (2136) 5023 1011.5 0
NP_001271200 (OMIM: 614217) activating signal coin ( 731) 4671 941.4 0
XP_011539159 (OMIM: 615684,615724) PREDICTED: prob (1294) 1103 231.4 5.4e-59
XP_011539157 (OMIM: 615684,615724) PREDICTED: prob (1393) 1103 231.4 5.8e-59
XP_011539152 (OMIM: 615684,615724) PREDICTED: prob (1435) 1103 231.4 6e-59
XP_011539151 (OMIM: 615684,615724) PREDICTED: prob (1435) 1103 231.4 6e-59
NP_001017975 (OMIM: 615684,615724) probable ATP-de (1435) 1103 231.4 6e-59
XP_011539154 (OMIM: 615684,615724) PREDICTED: prob (1435) 1103 231.4 6e-59
XP_011539153 (OMIM: 615684,615724) PREDICTED: prob (1435) 1103 231.4 6e-59
XP_016855980 (OMIM: 615684,615724) PREDICTED: prob (1391) 1050 220.8 8.7e-56
XP_016855981 (OMIM: 615684,615724) PREDICTED: prob (1114) 1013 213.5 1.1e-53
XP_016855983 (OMIM: 615684,615724) PREDICTED: prob ( 876) 977 206.3 1.3e-51
XP_016855984 (OMIM: 615684,615724) PREDICTED: prob ( 816) 941 199.1 1.8e-49
XP_016855985 (OMIM: 615684,615724) PREDICTED: prob ( 816) 941 199.1 1.8e-49
XP_016855979 (OMIM: 615684,615724) PREDICTED: prob (1408) 899 190.8 9.7e-47
XP_011539161 (OMIM: 615684,615724) PREDICTED: prob (1044) 843 179.6 1.7e-43
XP_016855982 (OMIM: 615684,615724) PREDICTED: prob ( 878) 684 148.0 4.7e-34
NP_071374 (OMIM: 614217) activating signal cointeg ( 111) 501 111.5 5.8e-24
NP_001284686 (OMIM: 606769) helicase POLQ-like iso ( 557) 246 60.8 5.2e-08
NP_001284685 (OMIM: 606769) helicase POLQ-like iso ( 604) 246 60.8 5.7e-08
XP_016863172 (OMIM: 606769) PREDICTED: helicase PO ( 604) 246 60.8 5.7e-08
XP_016863171 (OMIM: 606769) PREDICTED: helicase PO ( 604) 246 60.8 5.7e-08
XP_016863169 (OMIM: 606769) PREDICTED: helicase PO ( 928) 246 60.8 8.6e-08
XP_006714139 (OMIM: 606769) PREDICTED: helicase PO ( 950) 246 60.8 8.8e-08
XP_005262770 (OMIM: 606769) PREDICTED: helicase PO ( 995) 246 60.8 9.2e-08
XP_016863168 (OMIM: 606769) PREDICTED: helicase PO ( 997) 246 60.8 9.2e-08
NP_001284684 (OMIM: 606769) helicase POLQ-like iso (1034) 246 60.8 9.5e-08
XP_005262768 (OMIM: 606769) PREDICTED: helicase PO (1064) 246 60.8 9.8e-08
NP_598375 (OMIM: 606769) helicase POLQ-like isofor (1101) 246 60.8 1e-07
XP_011510654 (OMIM: 604419) PREDICTED: DNA polymer (2183) 242 60.1 3.4e-07
XP_011510650 (OMIM: 604419) PREDICTED: DNA polymer (2420) 242 60.1 3.8e-07
XP_011510645 (OMIM: 604419) PREDICTED: DNA polymer (2545) 242 60.1 3.9e-07
NP_955452 (OMIM: 604419) DNA polymerase theta [Hom (2590) 242 60.1 4e-07
XP_011510649 (OMIM: 604419) PREDICTED: DNA polymer (2591) 242 60.1 4e-07
XP_016861054 (OMIM: 604419) PREDICTED: DNA polymer (2201) 237 59.1 6.8e-07
XP_011513117 (OMIM: 600478,614602) PREDICTED: heli (1033) 216 54.9 6e-06
NP_008860 (OMIM: 600478,614602) helicase SKI2W [Ho (1246) 216 54.9 7.1e-06
NP_001160006 (OMIM: 605281) probable ATP-dependent ( 575) 207 53.0 1.2e-05
XP_011541799 (OMIM: 605281) PREDICTED: probable AT ( 678) 207 53.0 1.4e-05
NP_001136021 (OMIM: 605281) probable ATP-dependent ( 690) 207 53.0 1.4e-05
XP_011541797 (OMIM: 605281) PREDICTED: probable AT ( 698) 207 53.0 1.4e-05
NP_001160005 (OMIM: 605281) probable ATP-dependent ( 704) 207 53.0 1.4e-05
NP_077726 (OMIM: 605281) probable ATP-dependent RN ( 724) 207 53.0 1.5e-05
>>NP_006819 (OMIM: 614217) activating signal cointegrato (2202 aa)
initn: 14512 init1: 14512 opt: 14512 Z-score: 15597.8 bits: 2899.9 E(85289): 0
Smith-Waterman score: 14512; 99.9% identity (99.9% similar) in 2202 aa overlap (1-2202:1-2202)
10 20 30 40 50 60
pF1KB8 MALPRLTGALRSFSNVTKQDNYNEEVADLKIKRSKLHEQVLDLGLTWKKIIKFLNEKLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MALPRLTGALRSFSNVTKQDNYNEEVADLKIKRSKLHEQVLDLGLTWKKIIKFLNEKLEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SKMQSINEDLKDILHAAKQIVGTDNGREAIESGAAFLFMTFHLKDSVGHKETKAIKQMFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SKMQSINEDLKDILHAAKQIVGTDNGREAIESGAAFLFMTFHLKDSVGHKETKAIKQMFG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PFPSSSATAACNATNRIISHFSQDDFTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFD
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
NP_006 PFPSSSATAACNATNRIISHFSQDDLTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ELPINGETQKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ELPINGETQKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VPRVEDLCCTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VPRVEDLCCTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSND
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 HRFQALQDNCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HRFQALQDNCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SEGLMCFDPKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SEGLMCFDPKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 GAKMILPEGIQRENNKLYEEVRISYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRI
::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_006 GAKMILPEGIQRENNKLYEEVRIPYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 QSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 LSQIVRLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LSQIVRLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 LHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 FVHARNATVRTAMSLIERAKNCGHIPFFFSTQGHDYVLAEKQVQRSRNKQVRELFPDGFS
::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::
NP_006 FVHARNATVRTAMSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 IHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVD
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB8 LGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB8 EIALGTVTNVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EIALGTVTNVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB8 LDKAQMIRFEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LDKAQMIRFEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB8 FDQIKVREEEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FDQIKVREEEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB8 YVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 YVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB8 LEEKKLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LEEKKLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB8 SIYADFTWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SIYADFTWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIF
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB8 EPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEA
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB8 LYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAP
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB8 LKALVRERMDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LKALVRERMDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQN
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB8 RNYVQQVTILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RNYVQQVTILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB8 DWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLI
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB8 FVSSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FVSSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHH
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB8 AGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPI
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB8 TDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIA
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB8 GGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYC
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB8 IEIGEDNRSIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IEIGEDNRSIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPV
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB8 RHNEDHMNSELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RHNEDHMNSELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQA
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB8 LRVCQAMLDVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LRVCQAMLDVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKP
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB8 IMKGPHARGRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IMKGPHARGRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGI
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB8 SVKGSWDDLVEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SVKGSWDDLVEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPES
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB8 CAVTPRFPKSKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CAVTPRFPKSKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLY
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200
pF1KB8 FMSDCYLGLDQQYDIYLNVTQASLSAQVNTKVSDSLTDLALK
::::::::::::::::::::::::::::::::::::::::::
NP_006 FMSDCYLGLDQQYDIYLNVTQASLSAQVNTKVSDSLTDLALK
2170 2180 2190 2200
>>XP_011533696 (OMIM: 614217) PREDICTED: activating sign (2207 aa)
initn: 14335 init1: 14335 opt: 14492 Z-score: 15576.3 bits: 2895.9 E(85289): 0
Smith-Waterman score: 14492; 99.6% identity (99.7% similar) in 2207 aa overlap (1-2202:1-2207)
10 20 30 40 50
pF1KB8 MALPRLTGALRSFSNVTKQDNYNEEVADLK-----IKRSKLHEQVLDLGLTWKKIIKFLN
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_011 MALPRLTGALRSFSNVTKQDNYNEEVADLKVDLLKIKRSKLHEQVLDLGLTWKKIIKFLN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 EKLEKSKMQSINEDLKDILHAAKQIVGTDNGREAIESGAAFLFMTFHLKDSVGHKETKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKLEKSKMQSINEDLKDILHAAKQIVGTDNGREAIESGAAFLFMTFHLKDSVGHKETKAI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 KQMFGPFPSSSATAACNATNRIISHFSQDDFTALVQMTEKEHGDRVFFGKNLAFSFDMHD
::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
XP_011 KQMFGPFPSSSATAACNATNRIISHFSQDDLTALVQMTEKEHGDRVFFGKNLAFSFDMHD
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 LDHFDELPINGETQKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDHFDELPINGETQKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 KEMTEVPRVEDLCCTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEMTEVPRVEDLCCTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFL
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 NSSNDHRFQALQDNCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSSNDHRFQALQDNCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 EDLEVSEGLMCFDPKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDLEVSEGLMCFDPKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 SAFIAGAKMILPEGIQRENNKLYEEVRISYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMK
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_011 SAFIAGAKMILPEGIQRENNKLYEEVRIPYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMK
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 RLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVY
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 VAPMKALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAPMKALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 VGDVALSQIVRLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGDVALSQIVRLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYL
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 DVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAG
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB8 HQVMVFVHARNATVRTAMSLIERAKNCGHIPFFFSTQGHDYVLAEKQVQRSRNKQVRELF
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_011 HQVMVFVHARNATVRTAMSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELF
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB8 PDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKR
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB8 GSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB8 DNLNAEIALGTVTNVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNLNAEIALGTVTNVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVI
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB8 EVGRKLDKAQMIRFEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVGRKLDKAQMIRFEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIV
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB8 SKAEEFDQIKVREEEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKAEEFDQIKVREEEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSL
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KB8 ISDSAYVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISDSAYVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPP
1090 1100 1110 1120 1130 1140
1140 1150 1160 1170 1180 1190
pF1KB8 HILTRLEEKKLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HILTRLEEKKLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTV
1150 1160 1170 1180 1190 1200
1200 1210 1220 1230 1240 1250
pF1KB8 LRVTLSIYADFTWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRVTLSIYADFTWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVF
1210 1220 1230 1240 1250 1260
1260 1270 1280 1290 1300 1310
pF1KB8 TIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGC
1270 1280 1290 1300 1310 1320
1320 1330 1340 1350 1360 1370
pF1KB8 KAYEALYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAYEALYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKA
1330 1340 1350 1360 1370 1380
1380 1390 1400 1410 1420 1430
pF1KB8 VYIAPLKALVRERMDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYIAPLKALVRERMDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVS
1390 1400 1410 1420 1430 1440
1440 1450 1460 1470 1480 1490
pF1KB8 RSWQNRNYVQQVTILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSWQNRNYVQQVTILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALAN
1450 1460 1470 1480 1490 1500
1500 1510 1520 1530 1540 1550
pF1KB8 ARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPA
1510 1520 1530 1540 1550 1560
1560 1570 1580 1590 1600 1610
pF1KB8 KPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFG
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KB8 IGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRY
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KB8 VDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHL
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KB8 NAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIEL
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KB8 ELSYCIEIGEDNRSIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELSYCIEIGEDNRSIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEY
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KB8 TDLPVRHNEDHMNSELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TDLPVRHNEDHMNSELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKT
1870 1880 1890 1900 1910 1920
1920 1930 1940 1950 1960 1970
pF1KB8 VLDQALRVCQAMLDVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLDQALRVCQAMLDVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLF
1930 1940 1950 1960 1970 1980
1980 1990 2000 2010 2020 2030
pF1KB8 KKWKPIMKGPHARGRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKWKPIMKGPHARGRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPV
1990 2000 2010 2020 2030 2040
2040 2050 2060 2070 2080 2090
pF1KB8 INVGISVKGSWDDLVEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INVGISVKGSWDDLVEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHK
2050 2060 2070 2080 2090 2100
2100 2110 2120 2130 2140 2150
pF1KB8 GKPESCAVTPRFPKSKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKPESCAVTPRFPKSKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRY
2110 2120 2130 2140 2150 2160
2160 2170 2180 2190 2200
pF1KB8 IYTLYFMSDCYLGLDQQYDIYLNVTQASLSAQVNTKVSDSLTDLALK
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYTLYFMSDCYLGLDQQYDIYLNVTQASLSAQVNTKVSDSLTDLALK
2170 2180 2190 2200
>>XP_011533698 (OMIM: 614217) PREDICTED: activating sign (2104 aa)
initn: 13897 init1: 13897 opt: 13897 Z-score: 14936.7 bits: 2777.5 E(85289): 0
Smith-Waterman score: 13897; 99.9% identity (99.9% similar) in 2104 aa overlap (99-2202:1-2104)
70 80 90 100 110 120
pF1KB8 DLKDILHAAKQIVGTDNGREAIESGAAFLFMTFHLKDSVGHKETKAIKQMFGPFPSSSAT
::::::::::::::::::::::::::::::
XP_011 MTFHLKDSVGHKETKAIKQMFGPFPSSSAT
10 20 30
130 140 150 160 170 180
pF1KB8 AACNATNRIISHFSQDDFTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFDELPINGET
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
XP_011 AACNATNRIISHFSQDDLTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFDELPINGET
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB8 QKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTEVPRVEDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTEVPRVEDLC
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB8 CTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSNDHRFQALQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSNDHRFQALQD
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB8 NCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEVSEGLMCFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEVSEGLMCFD
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB8 PKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIAGAKMILPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIAGAKMILPE
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB8 GIQRENNKLYEEVRISYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETA
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIQRENNKLYEEVRIPYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETA
340 350 360 370 380 390
490 500 510 520 530 540
pF1KB8 YNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTD
400 410 420 430 440 450
550 560 570 580 590 600
pF1KB8 YFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLL
460 470 480 490 500 510
610 620 630 640 650 660
pF1KB8 ILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIG
520 530 540 550 560 570
670 680 690 700 710 720
pF1KB8 LFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMVFVHARNAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMVFVHARNAT
580 590 600 610 620 630
730 740 750 760 770 780
pF1KB8 VRTAMSLIERAKNCGHIPFFFSTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLR
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_011 VRTAMSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLR
640 650 660 670 680 690
790 800 810 820 830 840
pF1KB8 QDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQ
700 710 720 730 740 750
850 860 870 880 890 900
pF1KB8 IFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVT
760 770 780 790 800 810
910 920 930 940 950 960
pF1KB8 NVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIR
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KB8 FEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVRE
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KB8 EEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAAR
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KB8 IVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTV
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KB8 DKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTW
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KB8 NDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYY
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KB8 IRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFN
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360 1370 1380
pF1KB8 PVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRER
1240 1250 1260 1270 1280 1290
1390 1400 1410 1420 1430 1440
pF1KB8 MDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVT
1300 1310 1320 1330 1340 1350
1450 1460 1470 1480 1490 1500
pF1KB8 ILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQM
1360 1370 1380 1390 1400 1410
1510 1520 1530 1540 1550 1560
pF1KB8 GLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQT
1420 1430 1440 1450 1460 1470
1570 1580 1590 1600 1610 1620
pF1KB8 RLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDR
1480 1490 1500 1510 1520 1530
1630 1640 1650 1660 1670 1680
pF1KB8 KTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMG
1540 1550 1560 1570 1580 1590
1690 1700 1710 1720 1730 1740
pF1KB8 RAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQ
1600 1610 1620 1630 1640 1650
1750 1760 1770 1780 1790 1800
pF1KB8 DALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNR
1660 1670 1680 1690 1700 1710
1810 1820 1830 1840 1850 1860
pF1KB8 SIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMN
1720 1730 1740 1750 1760 1770
1870 1880 1890 1900 1910 1920
pF1KB8 SELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAML
1780 1790 1800 1810 1820 1830
1930 1940 1950 1960 1970 1980
pF1KB8 DVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHAR
1840 1850 1860 1870 1880 1890
1990 2000 2010 2020 2030 2040
pF1KB8 GRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDD
1900 1910 1920 1930 1940 1950
2050 2060 2070 2080 2090 2100
pF1KB8 LVEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFP
1960 1970 1980 1990 2000 2010
2110 2120 2130 2140 2150 2160
pF1KB8 KSKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLG
2020 2030 2040 2050 2060 2070
2170 2180 2190 2200
pF1KB8 LDQQYDIYLNVTQASLSAQVNTKVSDSLTDLALK
::::::::::::::::::::::::::::::::::
XP_011 LDQQYDIYLNVTQASLSAQVNTKVSDSLTDLALK
2080 2090 2100
>>XP_016865694 (OMIM: 614217) PREDICTED: activating sign (2104 aa)
initn: 13897 init1: 13897 opt: 13897 Z-score: 14936.7 bits: 2777.5 E(85289): 0
Smith-Waterman score: 13897; 99.9% identity (99.9% similar) in 2104 aa overlap (99-2202:1-2104)
70 80 90 100 110 120
pF1KB8 DLKDILHAAKQIVGTDNGREAIESGAAFLFMTFHLKDSVGHKETKAIKQMFGPFPSSSAT
::::::::::::::::::::::::::::::
XP_016 MTFHLKDSVGHKETKAIKQMFGPFPSSSAT
10 20 30
130 140 150 160 170 180
pF1KB8 AACNATNRIISHFSQDDFTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFDELPINGET
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
XP_016 AACNATNRIISHFSQDDLTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFDELPINGET
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB8 QKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTEVPRVEDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTEVPRVEDLC
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB8 CTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSNDHRFQALQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSNDHRFQALQD
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB8 NCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEVSEGLMCFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEVSEGLMCFD
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB8 PKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIAGAKMILPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIAGAKMILPE
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB8 GIQRENNKLYEEVRISYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETA
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIQRENNKLYEEVRIPYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETA
340 350 360 370 380 390
490 500 510 520 530 540
pF1KB8 YNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTD
400 410 420 430 440 450
550 560 570 580 590 600
pF1KB8 YFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLL
460 470 480 490 500 510
610 620 630 640 650 660
pF1KB8 ILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIG
520 530 540 550 560 570
670 680 690 700 710 720
pF1KB8 LFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMVFVHARNAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMVFVHARNAT
580 590 600 610 620 630
730 740 750 760 770 780
pF1KB8 VRTAMSLIERAKNCGHIPFFFSTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLR
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_016 VRTAMSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLR
640 650 660 670 680 690
790 800 810 820 830 840
pF1KB8 QDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQ
700 710 720 730 740 750
850 860 870 880 890 900
pF1KB8 IFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVT
760 770 780 790 800 810
910 920 930 940 950 960
pF1KB8 NVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIR
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KB8 FEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVRE
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KB8 EEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAAR
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KB8 IVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTV
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KB8 DKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTW
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KB8 NDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYY
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KB8 IRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFN
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360 1370 1380
pF1KB8 PVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRER
1240 1250 1260 1270 1280 1290
1390 1400 1410 1420 1430 1440
pF1KB8 MDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVT
1300 1310 1320 1330 1340 1350
1450 1460 1470 1480 1490 1500
pF1KB8 ILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQM
1360 1370 1380 1390 1400 1410
1510 1520 1530 1540 1550 1560
pF1KB8 GLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQT
1420 1430 1440 1450 1460 1470
1570 1580 1590 1600 1610 1620
pF1KB8 RLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDR
1480 1490 1500 1510 1520 1530
1630 1640 1650 1660 1670 1680
pF1KB8 KTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMG
1540 1550 1560 1570 1580 1590
1690 1700 1710 1720 1730 1740
pF1KB8 RAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQ
1600 1610 1620 1630 1640 1650
1750 1760 1770 1780 1790 1800
pF1KB8 DALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNR
1660 1670 1680 1690 1700 1710
1810 1820 1830 1840 1850 1860
pF1KB8 SIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMN
1720 1730 1740 1750 1760 1770
1870 1880 1890 1900 1910 1920
pF1KB8 SELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAML
1780 1790 1800 1810 1820 1830
1930 1940 1950 1960 1970 1980
pF1KB8 DVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHAR
1840 1850 1860 1870 1880 1890
1990 2000 2010 2020 2030 2040
pF1KB8 GRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDD
1900 1910 1920 1930 1940 1950
2050 2060 2070 2080 2090 2100
pF1KB8 LVEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFP
1960 1970 1980 1990 2000 2010
2110 2120 2130 2140 2150 2160
pF1KB8 KSKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLG
2020 2030 2040 2050 2060 2070
2170 2180 2190 2200
pF1KB8 LDQQYDIYLNVTQASLSAQVNTKVSDSLTDLALK
::::::::::::::::::::::::::::::::::
XP_016 LDQQYDIYLNVTQASLSAQVNTKVSDSLTDLALK
2080 2090 2100
>>XP_011533697 (OMIM: 614217) PREDICTED: activating sign (2104 aa)
initn: 13897 init1: 13897 opt: 13897 Z-score: 14936.7 bits: 2777.5 E(85289): 0
Smith-Waterman score: 13897; 99.9% identity (99.9% similar) in 2104 aa overlap (99-2202:1-2104)
70 80 90 100 110 120
pF1KB8 DLKDILHAAKQIVGTDNGREAIESGAAFLFMTFHLKDSVGHKETKAIKQMFGPFPSSSAT
::::::::::::::::::::::::::::::
XP_011 MTFHLKDSVGHKETKAIKQMFGPFPSSSAT
10 20 30
130 140 150 160 170 180
pF1KB8 AACNATNRIISHFSQDDFTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFDELPINGET
:::::::::::::::::.::::::::::::::::::::::::::::::::::::::::::
XP_011 AACNATNRIISHFSQDDLTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFDELPINGET
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB8 QKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTEVPRVEDLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTEVPRVEDLC
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB8 CTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSNDHRFQALQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSNDHRFQALQD
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB8 NCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEVSEGLMCFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEVSEGLMCFD
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB8 PKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIAGAKMILPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIAGAKMILPE
280 290 300 310 320 330
430 440 450 460 470 480
pF1KB8 GIQRENNKLYEEVRISYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETA
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIQRENNKLYEEVRIPYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETA
340 350 360 370 380 390
490 500 510 520 530 540
pF1KB8 YNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTD
400 410 420 430 440 450
550 560 570 580 590 600
pF1KB8 YFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLL
460 470 480 490 500 510
610 620 630 640 650 660
pF1KB8 ILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIG
520 530 540 550 560 570
670 680 690 700 710 720
pF1KB8 LFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMVFVHARNAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMVFVHARNAT
580 590 600 610 620 630
730 740 750 760 770 780
pF1KB8 VRTAMSLIERAKNCGHIPFFFSTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLR
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_011 VRTAMSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLR
640 650 660 670 680 690
790 800 810 820 830 840
pF1KB8 QDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQ
700 710 720 730 740 750
850 860 870 880 890 900
pF1KB8 IFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVT
760 770 780 790 800 810
910 920 930 940 950 960
pF1KB8 NVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIR
820 830 840 850 860 870
970 980 990 1000 1010 1020
pF1KB8 FEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVRE
880 890 900 910 920 930
1030 1040 1050 1060 1070 1080
pF1KB8 EEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAAR
940 950 960 970 980 990
1090 1100 1110 1120 1130 1140
pF1KB8 IVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTV
1000 1010 1020 1030 1040 1050
1150 1160 1170 1180 1190 1200
pF1KB8 DKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTW
1060 1070 1080 1090 1100 1110
1210 1220 1230 1240 1250 1260
pF1KB8 NDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYY
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KB8 IRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFN
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360 1370 1380
pF1KB8 PVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRER
1240 1250 1260 1270 1280 1290
1390 1400 1410 1420 1430 1440
pF1KB8 MDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVT
1300 1310 1320 1330 1340 1350
1450 1460 1470 1480 1490 1500
pF1KB8 ILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQM
1360 1370 1380 1390 1400 1410
1510 1520 1530 1540 1550 1560
pF1KB8 GLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQT
1420 1430 1440 1450 1460 1470
1570 1580 1590 1600 1610 1620
pF1KB8 RLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDR
1480 1490 1500 1510 1520 1530
1630 1640 1650 1660 1670 1680
pF1KB8 KTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMG
1540 1550 1560 1570 1580 1590
1690 1700 1710 1720 1730 1740
pF1KB8 RAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQ
1600 1610 1620 1630 1640 1650
1750 1760 1770 1780 1790 1800
pF1KB8 DALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNR
1660 1670 1680 1690 1700 1710
1810 1820 1830 1840 1850 1860
pF1KB8 SIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMN
1720 1730 1740 1750 1760 1770
1870 1880 1890 1900 1910 1920
pF1KB8 SELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAML
1780 1790 1800 1810 1820 1830
1930 1940 1950 1960 1970 1980
pF1KB8 DVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHAR
1840 1850 1860 1870 1880 1890
1990 2000 2010 2020 2030 2040
pF1KB8 GRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDD
1900 1910 1920 1930 1940 1950
2050 2060 2070 2080 2090 2100
pF1KB8 LVEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFP
1960 1970 1980 1990 2000 2010
2110 2120 2130 2140 2150 2160
pF1KB8 KSKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLG
2020 2030 2040 2050 2060 2070
2170 2180 2190 2200
pF1KB8 LDQQYDIYLNVTQASLSAQVNTKVSDSLTDLALK
::::::::::::::::::::::::::::::::::
XP_011 LDQQYDIYLNVTQASLSAQVNTKVSDSLTDLALK
2080 2090 2100
>>XP_016865695 (OMIM: 614217) PREDICTED: activating sign (1729 aa)
initn: 11426 init1: 11426 opt: 11426 Z-score: 12280.6 bits: 2285.8 E(85289): 0
Smith-Waterman score: 11426; 99.9% identity (99.9% similar) in 1729 aa overlap (474-2202:1-1729)
450 460 470 480 490 500
pF1KB8 SYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGA
::::::::::::::::::::::::::::::
XP_016 MKRLNRIQSIVFETAYNTNENMLICAPTGA
10 20 30
510 520 530 540 550 560
pF1KB8 GKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRRLEPLGIIVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRRLEPLGIIVKE
40 50 60 70 80 90
570 580 590 600 610 620
pF1KB8 LTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVHLLHEDRGPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVHLLHEDRGPV
100 110 120 130 140 150
630 640 650 660 670 680
pF1KB8 LESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQ
160 170 180 190 200 210
690 700 710 720 730 740
pF1KB8 TFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMVFVHARNATVRTAMSLIERAKNCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMVFVHARNATVRTAMSLIERAKNCG
220 230 240 250 260 270
750 760 770 780 790 800
pF1KB8 HIPFFFSTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLRQDRNLVENLFSNGHI
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLRQDRNLVENLFSNGHI
280 290 300 310 320 330
810 820 830 840 850 860
pF1KB8 KVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGE
340 350 360 370 380 390
870 880 890 900 910 920
pF1KB8 GIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVTNVEEAVKWISYTYLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVTNVEEAVKWISYTYLY
400 410 420 430 440 450
930 940 950 960 970 980
pF1KB8 VRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFEERTGYFSSTDLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFEERTGYFSSTDLGR
460 470 480 490 500 510
990 1000 1010 1020 1030 1040
pF1KB8 TASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDTLLSNFCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDTLLSNFCE
520 530 540 550 560 570
1050 1060 1070 1080 1090 1100
pF1KB8 LSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEIALRKRWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEIALRKRWP
580 590 600 610 620 630
1110 1120 1130 1140 1150 1160
pF1KB8 TMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTVDKLKDMRKDEIGHIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTVDKLKDMRKDEIGHIL
640 650 660 670 680 690
1170 1180 1190 1200 1210 1220
pF1KB8 HHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTWNDQVHGTVGEPWWIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTWNDQVHGTVGEPWWIW
700 710 720 730 740 750
1230 1240 1250 1260 1270 1280
pF1KB8 VEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVC
760 770 780 790 800 810
1290 1300 1310 1320 1330 1340
pF1KB8 IINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPVQTQIFHTLYHTDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPVQTQIFHTLYHTDC
820 830 840 850 860 870
1350 1360 1370 1380 1390 1400
pF1KB8 NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKK
880 890 900 910 920 930
1410 1420 1430 1440 1450 1460
pF1KB8 VIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGEERG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGEERG
940 950 960 970 980 990
1470 1480 1490 1500 1510 1520
pF1KB8 PVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPLE
1000 1010 1020 1030 1040 1050
1530 1540 1550 1560 1570 1580
pF1KB8 VHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAFLATEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAFLATEE
1060 1070 1080 1090 1100 1110
1590 1600 1610 1620 1630 1640
pF1KB8 DPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVL
1120 1130 1140 1150 1160 1170
1650 1660 1670 1680 1690 1700
pF1KB8 IATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVI
1180 1190 1200 1210 1220 1230
1710 1720 1730 1740 1750 1760
pF1KB8 LVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDALDYITWTYFFRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDALDYITWTYFFRRL
1240 1250 1260 1270 1280 1290
1770 1780 1790 1800 1810 1820
pF1KB8 IMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNRSIEPLTYGRIASYYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNRSIEPLTYGRIASYYY
1300 1310 1320 1330 1340 1350
1830 1840 1850 1860 1870 1880
pF1KB8 LKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMNSELAKCLPIESNPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMNSELAKCLPIESNPHS
1360 1370 1380 1390 1400 1410
1890 1900 1910 1920 1930 1940
pF1KB8 FDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVAANQGWLVTVLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVAANQGWLVTVLNI
1420 1430 1440 1450 1460 1470
1950 1960 1970 1980 1990 2000
pF1KB8 TNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHARGRTSIESLPELIHAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHARGRTSIESLPELIHAC
1480 1490 1500 1510 1520 1530
2010 2020 2030 2040 2050 2060
pF1KB8 GGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDDLVEGHNELSVSTLTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDDLVEGHNELSVSTLTA
1540 1550 1560 1570 1580 1590
2070 2080 2090 2100 2110 2120
pF1KB8 DKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFPKSKDEGWFLILGEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFPKSKDEGWFLILGEVD
1600 1610 1620 1630 1640 1650
2130 2140 2150 2160 2170 2180
pF1KB8 KRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLGLDQQYDIYLNVTQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLGLDQQYDIYLNVTQAS
1660 1670 1680 1690 1700 1710
2190 2200
pF1KB8 LSAQVNTKVSDSLTDLALK
:::::::::::::::::::
XP_016 LSAQVNTKVSDSLTDLALK
1720
>>NP_054733 (OMIM: 601664,610359) U5 small nuclear ribon (2136 aa)
initn: 4450 init1: 1694 opt: 5023 Z-score: 5392.4 bits: 1011.5 E(85289): 0
Smith-Waterman score: 5176; 40.2% identity (70.2% similar) in 2141 aa overlap (60-2182:103-2129)
30 40 50 60 70 80
pF1KB8 KIKRSKLHEQVLDLGLTWKKIIKFLNEKLEKSKMQSINEDLKDILHAAKQIVGTDNGREA
: : . : . .: . .: :. :.
NP_054 KRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALG-DQPRD-
80 90 100 110 120 130
90 100 110 120 130 140
pF1KB8 IESGAAFLFMTFHLKDSVGHKET-KAIKQMFGPFPSSSATAACNATNRIISHFSQDDFTA
: ::: .. .... :: : : ..: .. . : ..: .. .. ..
NP_054 ILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQTDDTRYHVLVNLGKKITDYGGDKEIQN
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB8 LVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFDELPINGETQKTISLD--------YKKFL
. .. :... : :. : : .. :. . ::... : : . :
NP_054 M-----DDNIDETY-GVNVQFESDEEEGDE----DVYGEVREEASDDDMEGDEAVVRCTL
200 210 220 230 240
210 220 230 240 250
pF1KB8 NEHL---QEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTEVPRVEDLCCTLYDMLAS
. .: : . . : .. . . .: ... :. . . : . ..: .
NP_054 SANLVASGELMSSKKKDLHPRDIDAFW--LQRQLSRFYDDAIVSQKKAD---EVLEILKT
250 260 270 280 290
260 270 280 290 300 310
pF1KB8 IKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSNDHRFQALQDNCKKILGE-
.. : ...: ::: . ...:. : :.:. :. : .: . . . ..:.:.
NP_054 ASDDRECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEK-----ERIMGKM
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB8 NAKPNYGCQVTIQSEQEKQ-LMKQYRREEKRIARREKKAGEDLEVSEGLMCFDPKELRIQ
.: :. . . : ::. :... : ...:. :... :::. : .: :
NP_054 EADPELSKFLYQLHETEKEDLIREERSRRERV--RQSRMDTDLET----MDLD------Q
360 370 380 390
380 390 400 410 420 430
pF1KB8 REQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIAGAKMILPEGIQRENN
.:: .: :: :.: . . . : :.:. . ::.: :..
NP_054 GGEAL-----AP---RQV-LDLEDLVFT----------QGSHFMANKRCQLPDGSFRRQR
400 410 420 430
440 450 460 470 480 490
pF1KB8 KLYEEVRISYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETAYNTNENM
: ::::.. .: :.. ::. . .. : . .: .:.:.: :::::: ....: .:.::.
NP_054 KGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENL
440 450 460 470 480 490
500 510 520 530 540 550
pF1KB8 LICAPTGAGKTNIAMLTVLHEIRQHFQQ-GVIKKNEFKIVYVAPMKALAAEMTDYFSRRL
:.::::::::::.:.. .:.:: .:... :.:. ..:::.:.:::..:. ::. :..::
NP_054 LLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRL
500 510 520 530 540 550
560 570 580 590 600 610
pF1KB8 EPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVH
:: : ::::: :: : :: ::..: ::::::..:::. :. . .:.:::.::::.:
NP_054 ATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKG-GERTYTQLVRLIILDEIH
560 570 580 590 600 610
620 630 640 650 660 670
pF1KB8 LLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDG
:::.:::::::..:::..:..: :: .:..::::::::: ::::::.:.: :::.::.
NP_054 LLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDN
620 630 640 650 660 670
680 690 700 710 720 730
pF1KB8 RFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAG-HQVMVFVHARNATVRTAM
:::::: ::..:: . ..... :.:. ::..... :: .::.::::.:. : .::
NP_054 SFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEH--AGKNQVLVFVHSRKETGKTAR
680 690 700 710 720 730
740 750 760 770 780 790
pF1KB8 SLIERAKNCGHIPFFFSTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLRQDRNL
.. . . . .:. . . . . .... .: ....:.: ::.:::::: : ::.:
NP_054 AIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTL
740 750 760 770 780 790
800 810 820 830 840 850
pF1KB8 VENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRA
::.::.. ::.::: :::::::::::::.:::::::.:. ..: ...:: ::..:..:::
NP_054 VEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRA
800 810 820 830 840 850
860 870 880 890 900 910
pF1KB8 GRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVTNVEEA
::::.: ::::.::.: .:..::.::.:. :::::.. .: : :::::.::.: :...:
NP_054 GRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDA
860 870 880 890 900 910
920 930 940 950 960 970
pF1KB8 VKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFEERT
:.:..:.:::.:: .: ::::: . :: : ..: .:: .. ::: ........:
NP_054 VNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKT
920 930 940 950 960 970
980 990 1000 1010 1020 1030
pF1KB8 GYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEE
: :. :.::: :::::: .:..:.:.:. .: ..: . : . :: .: ::::: :
NP_054 GNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLE
980 990 1000 1010 1020 1030
1040 1050 1060 1070 1080 1090
pF1KB8 LDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRAL
:. :: . . ..:. .:::.:::..::. ....:.:..: .::.:.:.:..::.
NP_054 LQKLLERV-PIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAI
1040 1050 1060 1070 1080 1090
1100 1110 1120 1130 1140 1150
pF1KB8 FEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTVDKLKD
:::.: . : .: . ::: :.::::.: ::::: :: ... ..:.:.. ..: :
NP_054 FEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYD
1100 1110 1120 1130 1140 1150
1160 1170 1180 1190 1200 1210
pF1KB8 MRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTWNDQVH
. ..:::.... ..: ... :: .:.. . . .:::::..:.: :.: :: :...::
NP_054 LNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVH
1160 1170 1180 1190 1200 1210
1220 1230 1240 1250 1260 1270
pF1KB8 GTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYYIRAVS
:. .: .:: ::: .. : : :::: :: . ... .:..: .:.::::: ::.::.::
NP_054 GS-SEAFWILVEDVDSEVILHHEYFL-LKAKY-AQDEHLITFFVPVFEPLPPQYFIRVVS
1220 1230 1240 1250 1260 1270
1280 1290 1300 1310 1320 1330
pF1KB8 DRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYN--FSHFNPVQ
::::. :. ..:.::::::..:: ::::::::::..:: .:.:.::. : :::.:
NP_054 DRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQ
1280 1290 1300 1310 1320 1330
1340 1350 1360 1370 1380 1390
pF1KB8 TQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDD
::.:.:.:..: ::..:::::::::. ::.::.:.. . .. :::.:..::... . :
NP_054 TQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMD
1340 1350 1360 1370 1380 1390
1400 1410 1420 1430 1440 1450
pF1KB8 WKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILI
: .....:.:::. :::... :.: ..:...:..:::::: .:: :..:. ::......
NP_054 WYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFV
1400 1410 1420 1430 1440 1450
1460 1470 1480 1490 1500 1510
pF1KB8 IDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLF
.::.::.: : ::::::: :: .:::. :.:.:::.::..:.::.:.: ::. . . :
NP_054 VDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTF
1460 1470 1480 1490 1500 1510
1520 1530 1540 1550 1560 1570
pF1KB8 NFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLT
::.:.:::::::.::::: .: :. :: ::...:: .::: :::..:: ::.:::::
NP_054 NFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLT
1520 1530 1540 1550 1560 1570
1580 1590 1600 1610 1620 1630
pF1KB8 ALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTV
:..... :.. . ...:. :... . . ::.:: :: :.:. : :: .:. :
NP_054 AIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLV
1580 1590 1600 1610 1620 1630
1640 1650 1660 1670 1680 1690
pF1KB8 EELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAG
:.:: . .::..:. .: ::.: :::::: :.::.:: . :::.:: :::::.:.:.
NP_054 EQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHAN
1640 1650 1660 1670 1680 1690
1700 1710 1720 1730 1740 1750
pF1KB8 RPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDAL
:: ::.:. ::. . ::::.:::::::.:::: : . ::.::::. :: .::::.
NP_054 RPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAV
1700 1710 1720 1730 1740 1750
1760 1770 1780 1790 1800 1810
pF1KB8 DYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNRSIE
::.:::...::. .::.:::: .:: .. ::.:.:..: .:: : :: : ::. ..
NP_054 DYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISI-EDEMDVA
1760 1770 1780 1790 1800 1810
1820 1830 1840 1850 1860 1870
pF1KB8 PLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMNSEL
::. : ::.:::... :...:. :. . ... :. :.:.: :: ..:.::.::.. .:
NP_054 PLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQL
1820 1830 1840 1850 1860 1870
1880 1890 1900 1910 1920 1930
pF1KB8 AKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVA
:. .: . : .:..::.:..::::::::: .: . ..::. .:..:.:. :: .::
NP_054 AQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSA-ELQSDTEEILSKAIRLIQACVDVL
1880 1890 1900 1910 1920 1930
1940 1950 1960 1970 1980 1990
pF1KB8 ANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHARGRT
...::: .: .: ::: :. : ::: : ::.. ..:. : .:
NP_054 SSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHI----------KRCTDKGVE
1940 1950 1960 1970 1980
2000 2010 2020 2030 2040 2050
pF1KB8 SIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDDLVE
:. .. :. .:. ..... : .. .. : .. : :
NP_054 SVFDIMEM------EDEERNALLQ--LTDSQIADVARFCNRYPNI---------------
1990 2000 2010
2060 2070 2080 2090 2100 2110
pF1KB8 GHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFPKSK
::: .. :. ... :. :.:.: . . . ...: ::...
NP_054 ---ELSYEVVDKDS--------IRSGGPVVVLVQLER------EEEVTGPVIAPLFPQKR
2020 2030 2040 2050 2060
2120 2130 2140 2150 2160 2170
pF1KB8 DEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLGLDQ
.:::....:.. . ::..::. .. .: .:.: .: : . :::::::: :.: ::
NP_054 EEGWWVVIGDAKSNSLISIKRLTLQQKAKV-KLDFVAPAT-GAHNYTLYFMSDAYMGCDQ
2070 2080 2090 2100 2110
2180 2190 2200
pF1KB8 QYDIYLNVTQASLSAQVNTKVSDSLTDLALK
.: . ..: .:
NP_054 EYKFSVDVKEAETDSDSD
2120 2130
>>XP_016859092 (OMIM: 601664,610359) PREDICTED: U5 small (2136 aa)
initn: 4450 init1: 1694 opt: 5023 Z-score: 5392.4 bits: 1011.5 E(85289): 0
Smith-Waterman score: 5176; 40.2% identity (70.2% similar) in 2141 aa overlap (60-2182:103-2129)
30 40 50 60 70 80
pF1KB8 KIKRSKLHEQVLDLGLTWKKIIKFLNEKLEKSKMQSINEDLKDILHAAKQIVGTDNGREA
: : . : . .: . .: :. :.
XP_016 KRDEDRHDINKMKGYTLLSEGIDEMVGIIYKPKTKETRETYEVLLSFIQAALG-DQPRD-
80 90 100 110 120 130
90 100 110 120 130 140
pF1KB8 IESGAAFLFMTFHLKDSVGHKET-KAIKQMFGPFPSSSATAACNATNRIISHFSQDDFTA
: ::: .. .... :: : : ..: .. . : ..: .. .. ..
XP_016 ILCGAADEVLAVLKNEKLRDKERRKEIDLLLGQTDDTRYHVLVNLGKKITDYGGDKEIQN
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB8 LVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFDELPINGETQKTISLD--------YKKFL
. .. :... : :. : : .. :. . ::... : : . :
XP_016 M-----DDNIDETY-GVNVQFESDEEEGDE----DVYGEVREEASDDDMEGDEAVVRCTL
200 210 220 230 240
210 220 230 240 250
pF1KB8 NEHL---QEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTEVPRVEDLCCTLYDMLAS
. .: : . . : .. . . .: ... :. . . : . ..: .
XP_016 SANLVASGELMSSKKKDLHPRDIDAFW--LQRQLSRFYDDAIVSQKKAD---EVLEILKT
250 260 270 280 290
260 270 280 290 300 310
pF1KB8 IKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSNDHRFQALQDNCKKILGE-
.. : ...: ::: . ...:. : :.:. :. : .: . . . ..:.:.
XP_016 ASDDRECENQLVLLLGFNTFDFIKVLRQHRMMILYCTLLASAQSEAEK-----ERIMGKM
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB8 NAKPNYGCQVTIQSEQEKQ-LMKQYRREEKRIARREKKAGEDLEVSEGLMCFDPKELRIQ
.: :. . . : ::. :... : ...:. :... :::. : .: :
XP_016 EADPELSKFLYQLHETEKEDLIREERSRRERV--RQSRMDTDLET----MDLD------Q
360 370 380 390
380 390 400 410 420 430
pF1KB8 REQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIAGAKMILPEGIQRENN
.:: .: :: :.: . . . : :.:. . ::.: :..
XP_016 GGEAL-----AP---RQV-LDLEDLVFT----------QGSHFMANKRCQLPDGSFRRQR
400 410 420 430
440 450 460 470 480 490
pF1KB8 KLYEEVRISYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETAYNTNENM
: ::::.. .: :.. ::. . .. : . .: .:.:.: :::::: ....: .:.::.
XP_016 KGYEEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRIQSKLYRAALETDENL
440 450 460 470 480 490
500 510 520 530 540 550
pF1KB8 LICAPTGAGKTNIAMLTVLHEIRQHFQQ-GVIKKNEFKIVYVAPMKALAAEMTDYFSRRL
:.::::::::::.:.. .:.:: .:... :.:. ..:::.:.:::..:. ::. :..::
XP_016 LLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKRL
500 510 520 530 540 550
560 570 580 590 600 610
pF1KB8 EPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVH
:: : ::::: :: : :: ::..: ::::::..:::. :. . .:.:::.::::.:
XP_016 ATYGITVAELTGDHQLCKEEISATQIIVCTPEKWDIITRKG-GERTYTQLVRLIILDEIH
560 570 580 590 600 610
620 630 640 650 660 670
pF1KB8 LLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDG
:::.:::::::..:::..:..: :: .:..::::::::: ::::::.:.: :::.::.
XP_016 LLHDDRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAKGLFYFDN
620 630 640 650 660 670
680 690 700 710 720 730
pF1KB8 RFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAG-HQVMVFVHARNATVRTAM
:::::: ::..:: . ..... :.:. ::..... :: .::.::::.:. : .::
XP_016 SFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEH--AGKNQVLVFVHSRKETGKTAR
680 690 700 710 720 730
740 750 760 770 780 790
pF1KB8 SLIERAKNCGHIPFFFSTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLRQDRNL
.. . . . .:. . . . . .... .: ....:.: ::.:::::: : ::.:
XP_016 AIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTL
740 750 760 770 780 790
800 810 820 830 840 850
pF1KB8 VENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRA
::.::.. ::.::: :::::::::::::.:::::::.:. ..: ...:: ::..:..:::
XP_016 VEDLFADKHIQVLVSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRA
800 810 820 830 840 850
860 870 880 890 900 910
pF1KB8 GRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVTNVEEA
::::.: ::::.::.: .:..::.::.:. :::::.. .: : :::::.::.: :...:
XP_016 GRPQYDTKGEGILITSHGELQYYLSLLNQQLPIESQMVSKLPDMLNAEIVLGNVQNAKDA
860 870 880 890 900 910
920 930 940 950 960 970
pF1KB8 VKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFEERT
:.:..:.:::.:: .: ::::: . :: : ..: .:: .. ::: ........:
XP_016 VNWLGYAYLYIRMLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKT
920 930 940 950 960 970
980 990 1000 1010 1020 1030
pF1KB8 GYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEE
: :. :.::: :::::: .:..:.:.:. .: ..: . : . :: .: ::::: :
XP_016 GNFQVTELGRIASHYYITNDTVQTYNQLLKPTLSEIELFRVFSLSSEFKNITVREEEKLE
980 990 1000 1010 1020 1030
1040 1050 1060 1070 1080 1090
pF1KB8 LDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRAL
:. :: . . ..:. .:::.:::..::. ....:.:..: .::.:.:.:..::.
XP_016 LQKLLERV-PIPVKESIEEPSAKINVLLQAFISQLKLEGFALMADMVYVTQSAGRLMRAI
1040 1050 1060 1070 1080 1090
1100 1110 1120 1130 1140 1150
pF1KB8 FEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTVDKLKD
:::.: . : .: . ::: :.::::.: ::::: :: ... ..:.:.. ..: :
XP_016 FEIVLNRGWAQLTDKTLNLCKMIDKRMWQSMCPLRQFRKLPEEVVKKIEKKNFPFERLYD
1100 1110 1120 1130 1140 1150
1160 1170 1180 1190 1200 1210
pF1KB8 MRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTWNDQVH
. ..:::.... ..: ... :: .:.. . . .:::::..:.: :.: :: :...::
XP_016 LNHNEIGELIRMPKMGKTIHKYVHLFPKLELSVHLQPITRSTLKVELTITPDFQWDEKVH
1160 1170 1180 1190 1200 1210
1220 1230 1240 1250 1260 1270
pF1KB8 GTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYYIRAVS
:. .: .:: ::: .. : : :::: :: . ... .:..: .:.::::: ::.::.::
XP_016 GS-SEAFWILVEDVDSEVILHHEYFL-LKAKY-AQDEHLITFFVPVFEPLPPQYFIRVVS
1220 1230 1240 1250 1260 1270
1280 1290 1300 1310 1320 1330
pF1KB8 DRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYN--FSHFNPVQ
::::. :. ..:.::::::..:: ::::::::::..:: .:.:.::. : :::.:
XP_016 DRWLSCETQLPVSFRHLILPEKYPPPTELLDLQPLPVSALRNSAFESLYQDKFPFFNPIQ
1280 1290 1300 1310 1320 1330
1340 1350 1360 1370 1380 1390
pF1KB8 TQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDD
::.:.:.:..: ::..:::::::::. ::.::.:.. . .. :::.:..::... . :
XP_016 TQVFNTVYNSDDNVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMD
1340 1350 1360 1370 1380 1390
1400 1410 1420 1430 1440 1450
pF1KB8 WKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILI
: .....:.:::. :::... :.: ..:...:..:::::: .:: :..:. ::......
XP_016 WYEKFQDRLNKKVVLLTGETSTDLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFV
1400 1410 1420 1430 1440 1450
1460 1470 1480 1490 1500 1510
pF1KB8 IDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLF
.::.::.: : ::::::: :: .:::. :.:.:::.::..:.::.:.: ::. . . :
XP_016 VDEVHLIGGENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSATSTF
1460 1470 1480 1490 1500 1510
1520 1530 1540 1550 1560 1570
pF1KB8 NFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLT
::.:.:::::::.::::: .: :. :: ::...:: .::: :::..:: ::.:::::
XP_016 NFHPNVRPVPLELHIQGFNISHTQTRLLSMAKPVYHAITKHSPKKPVIVFVPSRKQTRLT
1520 1530 1540 1550 1560 1570
1580 1590 1600 1610 1620 1630
pF1KB8 ALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTV
:..... :.. . ...:. :... . . ::.:: :: :.:. : :: .:. :
XP_016 AIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSDSTLKETLLNGVGYLHEGLSPMERRLV
1580 1590 1600 1610 1620 1630
1640 1650 1660 1670 1680 1690
pF1KB8 EELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAG
:.:: . .::..:. .: ::.: :::::: :.::.:: . :::.:: :::::.:.:.
XP_016 EQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKIHAYVDYPIYDVLQMVGHAN
1640 1650 1660 1670 1680 1690
1700 1710 1720 1730 1740 1750
pF1KB8 RPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDAL
:: ::.:. ::. . ::::.:::::::.:::: : . ::.::::. :: .::::.
XP_016 RPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMHDHFNAEIVTKTIENKQDAV
1700 1710 1720 1730 1740 1750
1760 1770 1780 1790 1800 1810
pF1KB8 DYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNRSIE
::.:::...::. .::.:::: .:: .. ::.:.:..: .:: : :: : ::. ..
XP_016 DYLTWTFLYRRMTQNPNYYNLQGISHRHLSDHLSELVEQTLSDLEQSKCISI-EDEMDVA
1760 1770 1780 1790 1800 1810
1820 1830 1840 1850 1860 1870
pF1KB8 PLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMNSEL
::. : ::.:::... :...:. :. . ... :. :.:.: :: ..:.::.::.. .:
XP_016 PLNLGMIAAYYYINYTTIELFSMSLNAKTKVRGLIEIISNAAEYENIPIRHHEDNLLRQL
1820 1830 1840 1850 1860 1870
1880 1890 1900 1910 1920 1930
pF1KB8 AKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVA
:. .: . : .:..::.:..::::::::: .: . ..::. .:..:.:. :: .::
XP_016 AQKVPHKLNNPKFNDPHVKTNLLLQAHLSRMQLSA-ELQSDTEEILSKAIRLIQACVDVL
1880 1890 1900 1910 1920 1930
1940 1950 1960 1970 1980 1990
pF1KB8 ANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHARGRT
...::: .: .: ::: :. : ::: : ::.. ..:. : .:
XP_016 SSNGWLSPALAAMELAQMVTQAMWSKDSYLKQLPHFTSEHI----------KRCTDKGVE
1940 1950 1960 1970 1980
2000 2010 2020 2030 2040 2050
pF1KB8 SIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDDLVE
:. .. :. .:. ..... : .. .. : .. : :
XP_016 SVFDIMEM------EDEERNALLQ--LTDSQIADVARFCNRYPNI---------------
1990 2000 2010
2060 2070 2080 2090 2100 2110
pF1KB8 GHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFPKSK
::: .. :. ... :. :.:.: . . . ...: ::...
XP_016 ---ELSYEVVDKDS--------IRSGGPVVVLVQLER------EEEVTGPVIAPLFPQKR
2020 2030 2040 2050 2060
2120 2130 2140 2150 2160 2170
pF1KB8 DEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLGLDQ
.:::....:.. . ::..::. .. .: .:.: .: : . :::::::: :.: ::
XP_016 EEGWWVVIGDAKSNSLISIKRLTLQQKAKV-KLDFVAPAT-GAHNYTLYFMSDAYMGCDQ
2070 2080 2090 2100 2110
2180 2190 2200
pF1KB8 QYDIYLNVTQASLSAQVNTKVSDSLTDLALK
.: . ..: .:
XP_016 EYKFSVDVKEAETDSDSD
2120 2130
>>NP_001271200 (OMIM: 614217) activating signal cointegr (731 aa)
initn: 4671 init1: 4671 opt: 4671 Z-score: 5021.9 bits: 941.4 E(85289): 0
Smith-Waterman score: 4671; 99.4% identity (99.7% similar) in 721 aa overlap (1-721:1-721)
10 20 30 40 50 60
pF1KB8 MALPRLTGALRSFSNVTKQDNYNEEVADLKIKRSKLHEQVLDLGLTWKKIIKFLNEKLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALPRLTGALRSFSNVTKQDNYNEEVADLKIKRSKLHEQVLDLGLTWKKIIKFLNEKLEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SKMQSINEDLKDILHAAKQIVGTDNGREAIESGAAFLFMTFHLKDSVGHKETKAIKQMFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKMQSINEDLKDILHAAKQIVGTDNGREAIESGAAFLFMTFHLKDSVGHKETKAIKQMFG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PFPSSSATAACNATNRIISHFSQDDFTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFD
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
NP_001 PFPSSSATAACNATNRIISHFSQDDLTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ELPINGETQKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELPINGETQKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VPRVEDLCCTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPRVEDLCCTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSND
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 HRFQALQDNCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRFQALQDNCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SEGLMCFDPKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEGLMCFDPKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 GAKMILPEGIQRENNKLYEEVRISYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRI
::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_001 GAKMILPEGIQRENNKLYEEVRIPYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 QSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 LSQIVRLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSQIVRLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 LHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: .
NP_001 LHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVHL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 FVHARNATVRTAMSLIERAKNCGHIPFFFSTQGHDYVLAEKQVQRSRNKQVRELFPDGFS
:
NP_001 FYLLLHLFICF
730
>>XP_011539159 (OMIM: 615684,615724) PREDICTED: probable (1294 aa)
initn: 876 init1: 265 opt: 1103 Z-score: 1180.1 bits: 231.4 E(85289): 5.4e-59
Smith-Waterman score: 1148; 34.7% identity (62.7% similar) in 708 aa overlap (1310-1977:123-814)
1280 1290 1300 1310 1320 1330
pF1KB8 EAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPVQTQIFHTLY
.: . : . .: .:: .:.. : :
XP_011 GMFKAPSFSVAFQPHDIQEVTENGLGSLKAVTEIPAKFRSIFKEFPYFNYIQSKAFDDLL
100 110 120 130 140 150
1340 1350 1360 1370 1380 1390
pF1KB8 HTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTS----KAVYIAPLKALVRERMDDWKVR
.:: : .. :::::::::. :::: :.. . : : ::.::.::: .:.:::: .
XP_011 YTDRNFVICAPTGSGKTVVFELAITRLLMEVPLPWLNIKIVYMAPIKALCSQRFDDWKEK
160 170 180 190 200 210
1400 1410 1420 1430 1440 1450
pF1KB8 IEEKLGKKVIELTGD-VTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDE
. .: . ::::: : :. : .: .:.:::::::...:.:.. . :: : ...:::
XP_011 FGP-IGLNCKELTGDTVMDDLFEIQHAHIIMTTPEKWDSMTRKWRDNSLVQLVRLFLIDE
220 230 240 250 260 270
1460 1470 1480 1490 1500
pF1KB8 IHLLGEE-RGPVLEVIVSRTNFISS--------HTEKPVRIVGLSTALANARDLADWLNI
.:.. .: :::.:::.::: . ..: : :.:.:..:... ::.:.:.::.
XP_011 VHIVKDENRGPTLEVVVSRMKTVQSVSQTLKNTSTAIPMRFVAVSATIPNAEDIAEWLSD
280 290 300 310 320 330
1510 1520 1530 1540 1550 1560
pF1KB8 KQMGLFNFR--PSVRPVPLEVHIQGFP---GQHYCPRMASMNKPAFQAIRSHSPAKPVLI
. .. : ::: :. . ::: .: ..: ..:. .: ::.:.
XP_011 GERPAVCLKMDESHRPVKLQKVVLGFPCSSNQTEFKFDLTLNYKIASVIQMYSDQKPTLV
340 350 360 370 380 390
1570 1580 1590 1600 1610
pF1KB8 FVSSRRQTRLTALELIAFLATEEDPKQWLNMDERE-MENIIATVRDSNLKLTLAFGIGMH
: ..:. .. .: :. .: : ....... ... .::::.:. : : ..:
XP_011 FCATRKGVQQAASVLV------KDAKFIMTVEQKQRLQKYAYSVRDSKLRDILKDGAAYH
400 410 420 430 440
1620 1630 1640 1650 1660 1670
pF1KB8 HAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFP
:::.. :::.:: :. . ::..::::: :::.:::::.::.: .: : . ..
XP_011 HAGMELSDRKVVEGAFTVGDLPVLFTTSTLAMGVNLPAHLVVIKSTMHYAGGL--FEEYS
450 460 470 480 490 500
1680 1690 1700 1710 1720 1730
pF1KB8 ITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEI
::.:::.::::::::: . :::... .: : ..: ::::: : .::::::
XP_011 ETDILQMIGRAGRPQFDTTATAVIMTRLSTRDKYIQMLACRDTVESSLHRHLIEHLNAEI
510 520 530 540 550 560
1740 1750 1760 1770 1780 1790
pF1KB8 AGGTITSKQDALDYITWTYFFRRLIMNPSYYNLGD-VSHDSVNKFLSHLIEKSLIELELS
. :::. . :...: : .. : . :::.:.... ...:... :..: :.: .:
XP_011 VLHTITDVNIAVEWIRSTLLYIRALKNPSHYGFASGLNKDGIEAKLQELCLKNLNDLSSL
570 580 590 600 610 620
1800 1810 1820 1830 1840 1850
pF1KB8 YCIEIGEDNRSIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDL
:.. : . ...: ::. ..::. .::: : .. . . .:..... .:. :.
XP_011 DLIKMDE-GVNFKPTEAGRLMAWYYITFETVKKFYT-ISGKETLSDLVTLIAGCKEFLDI
630 640 650 660 670 680
1860 1870 1880 1890 1900
pF1KB8 PVRHNEDHMNSELAKC-------LPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDY--
.: :: . . : : .:.:. . . . :.. :.::.:. .: :.
XP_011 QLRINEKKTLNTLNKDPNRITIRFPMEG---RIKTREMKVNCLIQAQLG--CIPIQDFAL
690 700 710 720 730
1910 1920 1930 1940 1950 1960
pF1KB8 DTDTKTVLDQALRVCQAMLD-VAANQGWLVTVLNITNLIQMVIQGRW---LKDSSLL---
:: .. .. :. . . : :::.. ....:: : . : :. :. :
XP_011 TQDTAKIFRHGSRITRWLSDFVAAQEKKFAVLLNSLILAKCFRCKLWENSLHVSKQLEKI
740 750 760 770 780 790
1970 1980 1990 2000 2010
pF1KB8 --TLPN-IENHHLHLFKKWKPIMKGPHARGRTSIESLPELIHACGGKDHVFSSMVESELH
:: : : : : :::
XP_011 GITLSNAIVNAGLTSFKKIEETDARELELILNRHPPFGTQIKETVMYLPKYELKVEQITR
800 810 820 830 840 850
2202 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:14:25 2016 done: Sat Nov 5 20:14:28 2016
Total Scan time: 18.380 Total Display time: 1.850
Function used was FASTA [36.3.4 Apr, 2011]