Result of FASTA (omim) for
pF1KB8408
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8408, 570 aa
1>>>pF1KB8408 570 - 570 aa - 570 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7462+/-0.000458; mu= 22.0317+/- 0.028
mean_var=65.9150+/-13.648, 0's: 0 Z-trim(109.2): 29 B-trim: 98 in 1/50
Lambda= 0.157973
statistics sampled from 17365 (17377) to 17365 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.568), E-opt: 0.2 (0.204), width: 16
Scan time: 9.990
The best scores are: opt bits E(85289)
NP_740754 (OMIM: 209900,236700,604896,605231) McKu ( 570) 3750 864.2 0
NP_061336 (OMIM: 209900,236700,604896,605231) McKu ( 570) 3750 864.2 0
NP_005989 (OMIM: 600114) T-complex protein 1 subun ( 545) 287 74.9 7.3e-13
NP_001008800 (OMIM: 600114) T-complex protein 1 su ( 507) 214 58.3 7e-08
NP_006421 (OMIM: 605142) T-complex protein 1 subun ( 539) 212 57.8 1e-07
NP_006422 (OMIM: 605139) T-complex protein 1 subun ( 535) 172 48.7 5.6e-05
NP_001753 (OMIM: 104613) T-complex protein 1 subun ( 531) 159 45.8 0.00043
NP_001185771 (OMIM: 605139) T-complex protein 1 su ( 488) 151 43.9 0.0014
NP_001243650 (OMIM: 605142) T-complex protein 1 su ( 509) 146 42.8 0.0033
NP_110379 (OMIM: 186980) T-complex protein 1 subun ( 556) 140 41.5 0.009
>>NP_740754 (OMIM: 209900,236700,604896,605231) McKusick (570 aa)
initn: 3750 init1: 3750 opt: 3750 Z-score: 4617.1 bits: 864.2 E(85289): 0
Smith-Waterman score: 3750; 100.0% identity (100.0% similar) in 570 aa overlap (1-570:1-570)
10 20 30 40 50 60
pF1KB8 MSRLEAKKPSLCKSEPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_740 MSRLEAKKPSLCKSEPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SALLSHLLVTHPILKILTASIQNHVSSFSDCGLFTAILCCNLIENVQRLGLTPTTVIRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_740 SALLSHLLVTHPILKILTASIQNHVSSFSDCGLFTAILCCNLIENVQRLGLTPTTVIRLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 KHLLSLCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_740 KHLLSLCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 AFLLTIPENAEGHIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_740 AFLLTIPENAEGHIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VALFCTTLSGDTSDTGEGTVVVSYGVSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_740 VALFCTTLSGDTSDTGEGTVVVSYGVSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_740 LKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 FHLIPNEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_740 FHLIPNEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 IRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGGEILTDMKYGHLWSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_740 IRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGGEILTDMKYGHLWSV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 QADSPCVANWPDLLSQCGCGLYNSQEELNWSFLRSTRRPFVPQSCLPHEAVGSASNLTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_740 QADSPCVANWPDLLSQCGCGLYNSQEELNWSFLRSTRRPFVPQSCLPHEAVGSASNLTLD
490 500 510 520 530 540
550 560 570
pF1KB8 CLTAKLSGLQVAVETANLILDLSYVIEDKN
::::::::::::::::::::::::::::::
NP_740 CLTAKLSGLQVAVETANLILDLSYVIEDKN
550 560 570
>>NP_061336 (OMIM: 209900,236700,604896,605231) McKusick (570 aa)
initn: 3750 init1: 3750 opt: 3750 Z-score: 4617.1 bits: 864.2 E(85289): 0
Smith-Waterman score: 3750; 100.0% identity (100.0% similar) in 570 aa overlap (1-570:1-570)
10 20 30 40 50 60
pF1KB8 MSRLEAKKPSLCKSEPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MSRLEAKKPSLCKSEPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SALLSHLLVTHPILKILTASIQNHVSSFSDCGLFTAILCCNLIENVQRLGLTPTTVIRLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SALLSHLLVTHPILKILTASIQNHVSSFSDCGLFTAILCCNLIENVQRLGLTPTTVIRLN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 KHLLSLCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 KHLLSLCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 AFLLTIPENAEGHIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 AFLLTIPENAEGHIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VALFCTTLSGDTSDTGEGTVVVSYGVSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 VALFCTTLSGDTSDTGEGTVVVSYGVSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 FHLIPNEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FHLIPNEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 IRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGGEILTDMKYGHLWSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 IRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGGEILTDMKYGHLWSV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 QADSPCVANWPDLLSQCGCGLYNSQEELNWSFLRSTRRPFVPQSCLPHEAVGSASNLTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 QADSPCVANWPDLLSQCGCGLYNSQEELNWSFLRSTRRPFVPQSCLPHEAVGSASNLTLD
490 500 510 520 530 540
550 560 570
pF1KB8 CLTAKLSGLQVAVETANLILDLSYVIEDKN
::::::::::::::::::::::::::::::
NP_061 CLTAKLSGLQVAVETANLILDLSYVIEDKN
550 560 570
>>NP_005989 (OMIM: 600114) T-complex protein 1 subunit g (545 aa)
initn: 193 init1: 65 opt: 287 Z-score: 351.9 bits: 74.9 E(85289): 7.3e-13
Smith-Waterman score: 289; 22.6% identity (54.5% similar) in 483 aa overlap (32-493:36-493)
10 20 30 40 50 60
pF1KB8 SRLEAKKPSLCKSEPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSS
:. .: ::.. .:.: . .:: : :....
NP_005 PVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIV-MTNDGN
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 ALLSHLLVTHPILKILTASIQNHVSSFSDCGLFTAILCCNLI---ENVQRLGLTPTTVIR
:.: .. : :: : . ... .: . :: ... :. . . ::.::
NP_005 AILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVIS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 LNKHLLSLCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALI
.. :. :: ::. . ::::.:.....: .. : .:.: ..: . . .
NP_005 AYRKALDDMISTLKKIS----IPVDISDSDMMLNIINSSITTKA---ISRWSSLACNIAL
130 140 150 160 170
180 190 200 210 220 230
pF1KB8 LRAFLLTIPENAEGHIILGK-SLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKST
. .. . ::.. .: . : . . . : . :: :: :..:. ..: :. :.
NP_005 DAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMIN-KDVTHPRMRRYIKNP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 ALKVALFCTTL---SGDTSDTGEGTVVVSYG--VSLENAVLDQLLNLGRQLISDHVDLVL
...:. ..: .:... : : .. ...:. ..:: . ..:. . :.:.
NP_005 --RIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCE---DIIQLKPDVVI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 CQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCT
.: : ...: : :: :. : . ... :.. .. . .. :. .
NP_005 TEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLE
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB8 AKFGSKHFFHLIPN--EATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGG
: . ..: .: . . :..:: . . .:.. . : :..: . .: .: . ::
NP_005 IKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGG
360 370 380 390 400 410
420 430 440 450 460
pF1KB8 GCTETHLAAYIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGG----
: .: .: : : :. : .: : .: .::: . .: .. :
NP_005 GASEMAVA-------HALTE---KSKAMTGVE-QWPYRAVAQALEVIPRTLIQNCGASTI
420 430 440 450 460
470 480 490 500 510 520
pF1KB8 EILTDMKYGHL------WSVQADSPCVANWPDLLSQCGCGLYNSQEELNWSFLRSTRRPF
..::... : :.:.... ... .:
NP_005 RLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRID
470 480 490 500 510 520
530 540 550 560 570
pF1KB8 VPQSCLPHEAVGSASNLTLDCLTAKLSGLQVAVETANLILDLSYVIEDKN
NP_005 DIVSGHKKKGDDQSRQGGAPDAGQE
530 540
>>NP_001008800 (OMIM: 600114) T-complex protein 1 subuni (507 aa)
initn: 153 init1: 65 opt: 214 Z-score: 262.4 bits: 58.3 E(85289): 7e-08
Smith-Waterman score: 216; 21.6% identity (53.1% similar) in 450 aa overlap (65-493:30-455)
40 50 60 70 80 90
pF1KB8 SCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDCGLF
... : :: : . ... .:
NP_001 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKIQVQHPAAKSMIEISRTQDEEVGDGTTS
10 20 30 40 50
100 110 120 130 140 150
pF1KB8 TAILCCNLI---ENVQRLGLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQILL
. :: ... :. . . ::.:: .. :. :: ::. . ::::.:.....:
NP_001 VIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKIS----IPVDISDSDMML
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB8 CLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGK-SLIVPLKGQRVI
.. : .:.: ..: . . . . .. . ::.. .: . : . . . : .
NP_001 NIINSSITTK---AISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGIIE
120 130 140 150 160 170
220 230 240 250 260
pF1KB8 DSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTL---SGDTSDTGEGTVVVSYG--
:: :: :..:. ..: :. :. ...:. ..: .:... : : ..
NP_001 DSCVLRGVMIN-KDVTHPRMRRYIKNP--RIVLLDSSLEYKKGESQTDIEITREEDFTRI
180 190 200 210 220
270 280 290 300 310 320
pF1KB8 VSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLT
...:. ..:: . ..:. . :.:. .: : ...: : :: :. : . ..
NP_001 LQMEEEYIQQLCE---DIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIA
230 240 250 260 270 280
330 340 350 360 370 380
pF1KB8 KMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHFFHLIPN--EATICSLLLCNRNDTAW
. :.. .. . .. :. . : . ..: .: . . :..:: . .
NP_001 RACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEIL
290 300 310 320 330 340
390 400 410 420 430 440
pF1KB8 DELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRHKTHNDPESILKDDECTQTEL
.:.. . : :..: . .: .: . ::: .: .: : : :. : .:
NP_001 SEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVA-------HALTE---KSKAMTGVE-
350 360 370 380 390
450 460 470 480 490
pF1KB8 QLIAEAFCSALESVVGSLEHDGG----EILTDMKYGHL------WSVQADSPCVANWPDL
: .: .::: . .: .. : ..::... : :.:.... ... .:
NP_001 QWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKEL
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB8 LSQCGCGLYNSQEELNWSFLRSTRRPFVPQSCLPHEAVGSASNLTLDCLTAKLSGLQVAV
NP_001 GIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPDAGQE
460 470 480 490 500
>>NP_006421 (OMIM: 605142) T-complex protein 1 subunit d (539 aa)
initn: 81 init1: 53 opt: 212 Z-score: 259.6 bits: 57.8 E(85289): 1e-07
Smith-Waterman score: 254; 21.4% identity (55.4% similar) in 448 aa overlap (33-466:48-470)
10 20 30 40 50 60
pF1KB8 RLEAKKPSLCKSEPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSSA
. . ::.: :....: : : :.....
NP_006 GRGKGAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGD-VTITNDGAT
20 30 40 50 60 70
70 80 90 100 110
pF1KB8 LLSHLLVTHPILKILTASIQNHVSSFSDCGLFTAILCCNLIENVQRL---GLTPTTVIRL
.:... : :: ..:. . . .: ..:. .:... .: :. :: . .
NP_006 ILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISES
80 90 100 110 120 130
120 130 140 150 160 170
pF1KB8 NKHLLSLCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALIL
.. : : : . . : ::..:. . :: . . :.:: .. . . .: . .
NP_006 FQKALEKGIEILTDMS---R-PVELSDRETLLNSATTSLNSK----VVSQYSSLLSPMSV
140 150 160 170 180
180 190 200 210 220 230
pF1KB8 RAFLLTIPENAEGHIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTAL
: . .: . . : :: : . : .. : :. ..:. . ..:.
NP_006 NAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEG-LVLTQKVSNSGITRVEKA---
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 KVALFCTTLSGDTSDTGEGTVVVSYGVSLENAVLDQ---LLNLGRQLISDHVDLVLCQK-
:..:. ::. .: .. .::: .... .. .. .::: .:. . ...: ::
NP_006 KIGLIQFCLSAPKTDM-DNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 VIHPSLK----QFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVC
... .:. .::: .:..: : .: . : ::.:.. . .. . ::.. .
NP_006 ILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAE
310 320 330 340 350 360
360 370 380 390 400
pF1KB8 TAKF-GSKHFFHLI--PNEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALL
... :: ..... . . .... . : . .: . . . :: :.. .:. .
NP_006 EVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIA
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB8 GGGCTETHLAAYIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGGEI
::: : .:: .: .. : . .. :.. :: .:.: . ..: ...:
NP_006 GGGAPEIELA--LRLTEYSRTLSGM-ESYCVR--------AFADAMEVIPSTLAENAGLN
430 440 450 460 470
470 480 490 500 510 520
pF1KB8 LTDMKYGHLWSVQADSPCVANWPDLLSQCGCGLYNSQEELNWSFLRSTRRPFVPQSCLPH
NP_006 PISTVTELRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKI
480 490 500 510 520 530
>>NP_006422 (OMIM: 605139) T-complex protein 1 subunit b (535 aa)
initn: 89 init1: 89 opt: 172 Z-score: 210.4 bits: 48.7 E(85289): 5.6e-05
Smith-Waterman score: 196; 21.9% identity (54.0% similar) in 415 aa overlap (32-429:38-429)
10 20 30 40 50 60
pF1KB8 SRLEAKKPSLCKSEPLTTERVRTTLSVLKRIVTSCYGPSGRLK-QLHNGFGGYVCTTSQS
.: : ::.: : : .: . . .:...
NP_006 PVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDG
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 SALLSHLLVTHPILKILTASIQNHVSSFSDCGLFTAILCCNLIENVQRL---GLTPTTVI
...:... : .: :.:. . . . .: ...: .:..... : . : :.:
NP_006 ATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTII
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 RLNKHLLSLCISYLKSETCGCRIPVDFSSTQI-----LLCLVRSILTSKPACMLTRKETE
.. . : : . :: .: .. :. .. . :.:: .::... .
NP_006 AGWREATKAAREALLSSA------VDHGSDEVKFRQDLMNIAGTTLSSK---LLTHHK-D
130 140 150 160 170
180 190 200 210 220 230
pF1KB8 HVSALILRAFL-LTIPENAEG-HIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRL
: . : ..: : : : :. ::: :.: : . :: . :.:.. ... . .
NP_006 HFTKLAVEAVLRLKGSGNLEAIHII--KKL-----GGSLADSYLDEGFLLD-KKIGVNQ-
180 190 200 210 220
240 250 260 270 280
pF1KB8 LPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYGVS---LENAVLDQLLNLGRQLISDH
: :. :. . : .. : . : :. .. .:.: ... . .....
NP_006 -P-KRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHG
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB8 VDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSV
.. . ...:. .:... ..::.. . .: :. .:: . ... . ::
NP_006 INCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSC
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB8 KDVCTAKFGSK---HFFHLIPNEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEP
: . . .: :: . .:: :...: . .. :: . . . :: :: :.:.
NP_006 KLIEEVMIGEDKLIHFSGVALGEA--CTIVLRGATQQILDEAERSLHDALCVLAQTVKDS
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB8 WALLGGGCTETHLAAYIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHD
.. ::::.: .: . . .. :
NP_006 RTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQ
410 420 430 440 450 460
>>NP_001753 (OMIM: 104613) T-complex protein 1 subunit z (531 aa)
initn: 52 init1: 52 opt: 159 Z-score: 194.4 bits: 45.8 E(85289): 0.00043
Smith-Waterman score: 178; 21.2% identity (51.7% similar) in 476 aa overlap (29-481:30-475)
10 20 30 40 50
pF1KB8 MSRLEAKKPSLCKSEPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQ
:. .. . ::.: .:.: .: .: . :..
NP_001 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSG-AGDIKLTKD
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 SSALLSHLLVTHPILKILT--ASIQNHVSSFSDCGLFTAILCCNLIENVQRL---GLTPT
...:: .. . :: .... :. :. ... : .... .:..... :: :
NP_001 GNVLLHEMQIQHPTASLIAKVATAQDDITG--DGTTSNVLIIGELLKQADLYISEGLHPR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 TVIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHV
. . . ...:. .. ... . :. ..:. : .: :. :: :
NP_001 IITEGFEAAKEKALQFLEE----VKVSREMDR-ETLIDVARTSLRTKVHAELADVLTEAV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 SALILRAFLLTIPENAEGHIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIK
: :.: .. : : : :. .: . :.... :.... . : .:
NP_001 VDSI-----LAIKKQDEP-IDLFMIEIMEMKHKSETDTSLIRGLVLDHGA----RHPDMK
180 190 200 210 220
240 250 260 270 280
pF1KB8 KSTALKVALFCT-TLSGDTSDTGEGTVVVSYG-----VSLENAVLD----QLLNLGRQLI
: . : :. .: . .... : : :. : .. ....: :..
NP_001 KRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVC
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB8 --SDHVDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPN
::. .:. :: : : . :. . :.:. : :: :: : ..:. .. :.
NP_001 GDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPD
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB8 SYGSVKDVCTAKFGSKHFFHLIP-NEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTL
: . : .: ..: . :. .::. . : . ..: . . .:.... ..
NP_001 CLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAI
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB8 KEPWALLGGGCTETHLA-AYIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGS
. .. :.: .:. .: : :.:: : .. . :: ..:: .:: .
NP_001 DDGCVVPGAGAVEVAMAEALIKHK----PS--------VKGRAQLGVQAFADALLIIPKV
410 420 430 440 450
470 480 490 500 510
pF1KB8 LEHDGG----EILTDMKYGHLWSVQADSPCVANWPDLLSQCGCGLYNSQEELNWSFLRST
: ...: : :. .. : : :
NP_001 LAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTV
460 470 480 490 500 510
>>NP_001185771 (OMIM: 605139) T-complex protein 1 subuni (488 aa)
initn: 89 init1: 89 opt: 151 Z-score: 185.1 bits: 43.9 E(85289): 0.0014
Smith-Waterman score: 175; 21.2% identity (54.0% similar) in 400 aa overlap (46-429:6-382)
20 30 40 50 60 70
pF1KB8 PLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILK
: .: . . .:......:... : .: :
NP_001 MDKILLSSGRDASLMVTNDGATILKNIGVDNPAAK
10 20 30
80 90 100 110 120 130
pF1KB8 ILTASIQNHVSSFSDCGLFTAILCCNLIENVQRL---GLTPTTVIRLNKHLLSLCISYLK
.:. . . . .: ...: .:..... : . : :.: .. . :
NP_001 VLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWREATKAAREALL
40 50 60 70 80 90
140 150 160 170 180
pF1KB8 SETCGCRIPVDFSSTQI-----LLCLVRSILTSKPACMLTRKETEHVSALILRAFL-LTI
: . :: .: .. :. .. . :.:: .::... .: . : ..: : :
NP_001 SSA------VDHGSDEVKFRQDLMNIAGTTLSSK---LLTHHK-DHFTKLAVEAVLRLKG
100 110 120 130 140
190 200 210 220 230 240
pF1KB8 PENAEG-HIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFC
: :. ::: :.: : . :: . :.:.. ... . . : :. :. .
NP_001 SGNLEAIHII--KKL-----GGSLADSYLDEGFLLD-KKIGVNQ--P-KRIENAKILIAN
150 160 170 180 190
250 260 270 280 290 300
pF1KB8 TTLSGDTSDTGEGTVVVSYGVS---LENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLK
: .. : . : :. .. .:.: ... . ..... .. . ...:. .
NP_001 TGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPE
200 210 220 230 240 250
310 320 330 340 350
pF1KB8 QFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSK---H
:... ..::.. . .: :. .:: . ... . :: : . . .: :
NP_001 QLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIH
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB8 FFHLIPNEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAA
: . .:: :...: . .. :: . . . :: :: :.:. .. ::::.: .:
NP_001 FSGVALGEA--CTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEMLMAH
320 330 340 350 360 370
420 430 440 450 460 470
pF1KB8 YIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGGEILTDMKYGHLWS
. . .. :
NP_001 AVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGNTTAGLD
380 390 400 410 420 430
>>NP_001243650 (OMIM: 605142) T-complex protein 1 subuni (509 aa)
initn: 110 init1: 53 opt: 146 Z-score: 178.7 bits: 42.8 E(85289): 0.0033
Smith-Waterman score: 188; 21.4% identity (54.7% similar) in 384 aa overlap (97-466:81-440)
70 80 90 100 110 120
pF1KB8 LLVTHPILKILTASIQNHVSSFSDCGLFTAILCCNLIENVQRL---GLTPTTVIRLNKHL
:. .:... .: :. :: . . ..
NP_001 SLGPKGMDKMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 LSLCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVSALILRAFL
: : : . . : ::..:. . :: . . :.:: .. . . .: . . : .
NP_001 LEKGIEILTDMS---R-PVELSDRETLLNSATTSLNSK----VVSQYSSLLSPMSVNAVM
120 130 140 150 160
190 200 210 220 230 240
pF1KB8 LTIPENAEGHIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVAL
.: . . : :: : . : .. : :. ..:. . ..:. :..:
NP_001 KVIDPATATSVDLRDIKIVKKLGGTIDDCELVEG-LVLTQKVSNSGITRVEKA---KIGL
170 180 190 200 210
250 260 270 280 290
pF1KB8 FCTTLSGDTSDTGEGTVVVSYGVSLENAVLDQ---LLNLGRQLISDHVDLVLCQK-VIHP
. ::. .: .. .::: .... .. .. .::: .:. . ...: :: ...
NP_001 IQFCLSAPKTDM-DNQIVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRD
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB8 SLK----QFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCTAKF
.:. .::: .:..: : .: . : ::.:.. . .. . ::.. . ...
NP_001 ALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNL
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB8 -GSKHFFHLI--PNEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGC
:: ..... . . .... . : . .: . . . :: :.. .:. . :::
NP_001 NGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGA
340 350 360 370 380 390
420 430 440 450 460 470
pF1KB8 TETHLAAYIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGGEILTDM
: .:: .: .. : . .. :.. :: .:.: . ..: ...:
NP_001 PEIELA--LRLTEYSRTLSGM-ESYCVR--------AFADAMEVIPSTLAENAGLNPIST
400 410 420 430 440
480 490 500 510 520 530
pF1KB8 KYGHLWSVQADSPCVANWPDLLSQCGCGLYNSQEELNWSFLRSTRRPFVPQSCLPHEAVG
NP_001 VTELRNRHAQGEKTAGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDDVV
450 460 470 480 490 500
>>NP_110379 (OMIM: 186980) T-complex protein 1 subunit a (556 aa)
initn: 74 init1: 74 opt: 140 Z-score: 170.8 bits: 41.5 E(85289): 0.009
Smith-Waterman score: 164; 21.0% identity (53.1% similar) in 433 aa overlap (15-423:15-425)
10 20 30 40 50 60
pF1KB8 MSRLEAKKPSLCKSEPLTTERVRTTLSVLKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQS
: . .. : .. :. :: : :: : :.: . .: : :...
NP_110 MEGPLSVFGDRSTGETIRSQNVMAAASI-ANIVKSSLGPVGLDKMLVDDIGD-VTITNDG
10 20 30 40 50
70 80 90 100 110
pF1KB8 SALLSHLLVTHPILKILT--ASIQNHVSSFSDCGLFTAILCCNLIENVQRL---GLTPTT
...:. : : :: :.: :..:.. .: ..:. .:..:...: . ::.
NP_110 ATILKLLEVEHPAAKVLCELADLQDK--EVGDGTTSVVIIAAELLKNADELVKQKIHPTS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 VIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQILLCLVRSILTSKPACMLTRKETEHVS
:: . . . :.. . . .: . . :. ... ..:: . . . .
NP_110 VISGYRLACKEAVRYINENLI---VNTDELGRDCLINAAKTSMSSK----IIGINGDFFA
120 130 140 150 160
180 190 200 210 220 230
pF1KB8 ALILRAFLLTIPENAEGHIILGKSLIVPLK--GQRVIDSTVLPGILIEMSEVQLMRLLPI
... : : . .:. . . :: :. ..: .. : .. : . .:
NP_110 NMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGY--ALNCVVGSQGMP-
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB8 KKSTALKVALFCTTLSGDTSDTGEGTVVVSYGVSLENAVLDQLLNLGRQLISDHVDLVLC
:. . :.: : .: . . :. :: .. . :::. . .. ..... .:
NP_110 KRIVNAKIA--CLDFSLQKTKMKLGVQVV---IT-DPEKLDQIRQRESDITKERIQKILA
230 240 250 260 270 280
300 310 320 330 340
pF1KB8 Q--KVIHPS-------LKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNS-
.:: . :: :.. .:. :. .. ..: .:. ...:... .
NP_110 TGANVILTTGGIDDMCLKYFVEAG-AMAVRRVLKRDLKRIAKASGATILSTLANLEGEET
290 300 310 320 330
350 360 370 380 390
pF1KB8 -----YGSVKDVCTAKFGSKHFFHLIPNEA--TICSLLLCNRNDTAWDELKLTCQTALHV
:....: .. . ... :: : : :..: . :: ::.. . . :: :
NP_110 FEAAMLGQAEEVVQERICDDELI-LIKNTKARTSASIILRGANDFMCDEMERSLHDALCV
340 350 360 370 380 390
400 410 420 430 440 450
pF1KB8 LQLTLKEPWALLGGGCTETHLAAYIRHKTHNDPESILKDDECTQTELQLIAEAFCSALES
.. .:. .. ::: .:. :. :...
NP_110 VKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQ
400 410 420 430 440 450
570 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:41:18 2016 done: Fri Nov 4 12:41:19 2016
Total Scan time: 9.990 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]