Result of FASTA (omim) for
pF1KB8403
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8403, 715 aa
1>>>pF1KB8403 715 - 715 aa - 715 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7728+/-0.000434; mu= 12.9054+/- 0.027
mean_var=103.1951+/-20.981, 0's: 0 Z-trim(112.6): 41 B-trim: 455 in 2/52
Lambda= 0.126254
statistics sampled from 21595 (21635) to 21595 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.254), width: 16
Scan time: 11.730
The best scores are: opt bits E(85289)
NP_009126 (OMIM: 605252) DNA polymerase iota [Homo ( 740) 4692 866.0 0
XP_011524098 (OMIM: 605252) PREDICTED: DNA polymer ( 672) 4411 814.7 0
XP_005258245 (OMIM: 605252) PREDICTED: DNA polymer ( 672) 4411 814.7 0
XP_011524099 (OMIM: 605252) PREDICTED: DNA polymer ( 430) 2427 453.3 9.3e-127
XP_006722441 (OMIM: 605252) PREDICTED: DNA polymer ( 430) 2427 453.3 9.3e-127
XP_005258249 (OMIM: 605252) PREDICTED: DNA polymer ( 401) 2419 451.8 2.4e-126
XP_011541769 (OMIM: 605650) PREDICTED: DNA polymer ( 794) 320 69.6 5.3e-11
XP_016865050 (OMIM: 605650) PREDICTED: DNA polymer ( 818) 320 69.6 5.5e-11
XP_011541765 (OMIM: 605650) PREDICTED: DNA polymer ( 884) 320 69.6 5.8e-11
XP_011541766 (OMIM: 605650) PREDICTED: DNA polymer ( 884) 320 69.6 5.8e-11
XP_016865047 (OMIM: 605650) PREDICTED: DNA polymer ( 884) 320 69.6 5.8e-11
XP_005248591 (OMIM: 605650) PREDICTED: DNA polymer ( 884) 320 69.6 5.8e-11
XP_016865052 (OMIM: 605650) PREDICTED: DNA polymer ( 780) 317 69.1 7.6e-11
NP_001332851 (OMIM: 605650) DNA polymerase kappa i ( 780) 317 69.1 7.6e-11
NP_001332850 (OMIM: 605650) DNA polymerase kappa i ( 804) 317 69.1 7.8e-11
XP_016865049 (OMIM: 605650) PREDICTED: DNA polymer ( 870) 317 69.1 8.4e-11
XP_016865048 (OMIM: 605650) PREDICTED: DNA polymer ( 870) 317 69.1 8.4e-11
NP_057302 (OMIM: 605650) DNA polymerase kappa isof ( 870) 317 69.1 8.4e-11
XP_011513000 (OMIM: 278750,603968) PREDICTED: DNA ( 589) 276 61.5 1.1e-08
NP_001278898 (OMIM: 278750,603968) DNA polymerase ( 589) 276 61.5 1.1e-08
XP_005249243 (OMIM: 278750,603968) PREDICTED: DNA ( 651) 276 61.6 1.2e-08
NP_006493 (OMIM: 278750,603968) DNA polymerase eta ( 713) 276 61.6 1.3e-08
XP_016859801 (OMIM: 606134) PREDICTED: DNA repair (1286) 246 56.2 9.2e-07
XP_016859800 (OMIM: 606134) PREDICTED: DNA repair (1287) 246 56.2 9.2e-07
NP_001308383 (OMIM: 606134) DNA repair protein REV (1287) 246 56.2 9.2e-07
XP_016859799 (OMIM: 606134) PREDICTED: DNA repair (1287) 246 56.2 9.2e-07
XP_016859798 (OMIM: 606134) PREDICTED: DNA repair (1297) 246 56.2 9.2e-07
NP_001278899 (OMIM: 278750,603968) DNA polymerase ( 414) 235 54.0 1.4e-06
NP_001308388 (OMIM: 606134) DNA repair protein REV ( 728) 235 54.1 2.3e-06
NP_001308389 (OMIM: 606134) DNA repair protein REV ( 728) 235 54.1 2.3e-06
XP_016859804 (OMIM: 606134) PREDICTED: DNA repair ( 758) 235 54.1 2.3e-06
XP_016859803 (OMIM: 606134) PREDICTED: DNA repair ( 761) 235 54.1 2.3e-06
NP_001308387 (OMIM: 606134) DNA repair protein REV ( 761) 235 54.1 2.3e-06
XP_011509643 (OMIM: 606134) PREDICTED: DNA repair ( 761) 235 54.1 2.3e-06
NP_001308384 (OMIM: 606134) DNA repair protein REV (1180) 235 54.2 3.4e-06
NP_001032961 (OMIM: 606134) DNA repair protein REV (1250) 235 54.2 3.6e-06
NP_057400 (OMIM: 606134) DNA repair protein REV1 i (1251) 235 54.2 3.6e-06
XP_016859802 (OMIM: 606134) PREDICTED: DNA repair (1358) 235 54.3 3.9e-06
>>NP_009126 (OMIM: 605252) DNA polymerase iota [Homo sap (740 aa)
initn: 4692 init1: 4692 opt: 4692 Z-score: 4622.7 bits: 866.0 E(85289): 0
Smith-Waterman score: 4692; 99.6% identity (99.9% similar) in 715 aa overlap (1-715:26-740)
10 20 30
pF1KB8 MELADVGAAASSQGVHDQVLPTPNASSRVIVHVDL
:::::::::::::::::::::::::::::::::::
NP_009 MEKLGVEPEEEGGGDDDEEDAEAWAMELADVGAAASSQGVHDQVLPTPNASSRVIVHVDL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 DCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVN
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 GEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB8 HVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 HVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKP
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB8 NQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGI
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB8 SVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCTSEVEAKNKIEELLASLLNRVCQD
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
NP_009 SVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB8 GRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTGNYDVMTPMVDILMKLFRNMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTGNYDVMTPMVDILMKLFRNMV
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB8 NVKMPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLSTTSRSGKHSFKMKDTHMEDFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NVKMPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLSTTSRSGKHSFKMKDTHMEDFPK
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB8 DKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEFPLCSLPEGVDQEVSKQLPVDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
NP_009 DKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEFPLCSLPEGVDQEVFKQLPVDIQ
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB8 EEILSGKSREKFQGKGSVSCPLHASRGVLSFFSKKQMQDIPINPRDHLSSSKQVSSVSPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EEILSGKSREKFQGKGSVSCPLHASRGVLSFFSKKQMQDIPINPRDHLSSSKQVSSVSPC
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB8 EPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFHSFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFHSFP
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB8 NLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKITFPSDIDPQVFYELPEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKITFPSDIDPQVFYELPEAV
670 680 690 700 710 720
700 710
pF1KB8 QKELLAEWKRTGSDFHIGHK
::::::::::.:::::::::
NP_009 QKELLAEWKRAGSDFHIGHK
730 740
>>XP_011524098 (OMIM: 605252) PREDICTED: DNA polymerase (672 aa)
initn: 4411 init1: 4411 opt: 4411 Z-score: 4346.8 bits: 814.7 E(85289): 0
Smith-Waterman score: 4411; 99.6% identity (99.9% similar) in 672 aa overlap (44-715:1-672)
20 30 40 50 60 70
pF1KB8 GVHDQVLPTPNASSRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKL
::::::::::::::::::::::::::::::
XP_011 MISNPELKDKPLGVQQKYLVVTCNYEARKL
10 20 30
80 90 100 110 120 130
pF1KB8 GVKKLMNVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVKKLMNVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLT
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 EMVEKRLQQLQSDELSAVTVSGHVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMVEKRLQQLQSDELSAVTVSGHVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGL
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB8 TGCAGVASNKLLAKLVSGVFKPNQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGCAGVASNKLLAKLVSGVFKPNQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEAL
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB8 GINSVRDLQTFSPKILEKELGISVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_011 GINSVRDLQTFSPKILEKELGISVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCSS
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB8 EVEAKNKIEELLASLLNRVCQDGRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVEAKNKIEELLASLLNRVCQDGRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLG
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB8 TGNYDVMTPMVDILMKLFRNMVNVKMPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGNYDVMTPMVDILMKLFRNMVNVKMPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLS
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB8 TTSRSGKHSFKMKDTHMEDFPKDKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTSRSGKHSFKMKDTHMEDFPKDKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEF
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB8 PLCSLPEGVDQEVSKQLPVDIQEEILSGKSREKFQGKGSVSCPLHASRGVLSFFSKKQMQ
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLCSLPEGVDQEVFKQLPVDIQEEILSGKSREKFQGKGSVSCPLHASRGVLSFFSKKQMQ
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB8 DIPINPRDHLSSSKQVSSVSPCEPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIPINPRDHLSSSKQVSSVSPCEPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGP
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB8 KEPQGFHFTNSNPAVSAFHSFPNLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEPQGFHFTNSNPAVSAFHSFPNLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSV
580 590 600 610 620 630
680 690 700 710
pF1KB8 DEKITFPSDIDPQVFYELPEAVQKELLAEWKRTGSDFHIGHK
::::::::::::::::::::::::::::::::.:::::::::
XP_011 DEKITFPSDIDPQVFYELPEAVQKELLAEWKRAGSDFHIGHK
640 650 660 670
>>XP_005258245 (OMIM: 605252) PREDICTED: DNA polymerase (672 aa)
initn: 4411 init1: 4411 opt: 4411 Z-score: 4346.8 bits: 814.7 E(85289): 0
Smith-Waterman score: 4411; 99.6% identity (99.9% similar) in 672 aa overlap (44-715:1-672)
20 30 40 50 60 70
pF1KB8 GVHDQVLPTPNASSRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKL
::::::::::::::::::::::::::::::
XP_005 MISNPELKDKPLGVQQKYLVVTCNYEARKL
10 20 30
80 90 100 110 120 130
pF1KB8 GVKKLMNVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVKKLMNVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLT
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 EMVEKRLQQLQSDELSAVTVSGHVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EMVEKRLQQLQSDELSAVTVSGHVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGL
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB8 TGCAGVASNKLLAKLVSGVFKPNQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGCAGVASNKLLAKLVSGVFKPNQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEAL
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB8 GINSVRDLQTFSPKILEKELGISVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:
XP_005 GINSVRDLQTFSPKILEKELGISVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCSS
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB8 EVEAKNKIEELLASLLNRVCQDGRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVEAKNKIEELLASLLNRVCQDGRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLG
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB8 TGNYDVMTPMVDILMKLFRNMVNVKMPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGNYDVMTPMVDILMKLFRNMVNVKMPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLS
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB8 TTSRSGKHSFKMKDTHMEDFPKDKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTSRSGKHSFKMKDTHMEDFPKDKETNRDFLPSGRIESTRTRESPLDTTNFSKEKDINEF
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB8 PLCSLPEGVDQEVSKQLPVDIQEEILSGKSREKFQGKGSVSCPLHASRGVLSFFSKKQMQ
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLCSLPEGVDQEVFKQLPVDIQEEILSGKSREKFQGKGSVSCPLHASRGVLSFFSKKQMQ
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB8 DIPINPRDHLSSSKQVSSVSPCEPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DIPINPRDHLSSSKQVSSVSPCEPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGP
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB8 KEPQGFHFTNSNPAVSAFHSFPNLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEPQGFHFTNSNPAVSAFHSFPNLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSV
580 590 600 610 620 630
680 690 700 710
pF1KB8 DEKITFPSDIDPQVFYELPEAVQKELLAEWKRTGSDFHIGHK
::::::::::::::::::::::::::::::::.:::::::::
XP_005 DEKITFPSDIDPQVFYELPEAVQKELLAEWKRAGSDFHIGHK
640 650 660 670
>>XP_011524099 (OMIM: 605252) PREDICTED: DNA polymerase (430 aa)
initn: 2427 init1: 2427 opt: 2427 Z-score: 2396.7 bits: 453.3 E(85289): 9.3e-127
Smith-Waterman score: 2427; 99.7% identity (100.0% similar) in 375 aa overlap (1-375:26-400)
10 20 30
pF1KB8 MELADVGAAASSQGVHDQVLPTPNASSRVIVHVDL
:::::::::::::::::::::::::::::::::::
XP_011 MEKLGVEPEEEGGGDDDEEDAEAWAMELADVGAAASSQGVHDQVLPTPNASSRVIVHVDL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 DCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVN
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 GEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB8 HVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKP
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB8 NQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGI
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB8 SVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCTSEVEAKNKIEELLASLLNRVCQD
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_011 SVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB8 GRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTGNYDVMTPMVDILMKLFRNMV
::::::::::::::::::::::::::::::::::::::::
XP_011 GRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTGLQSPDFCASSLMQRRLEDKL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB8 NVKMPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLSTTSRSGKHSFKMKDTHMEDFPK
XP_011 VKLEGVFTKH
430
>>XP_006722441 (OMIM: 605252) PREDICTED: DNA polymerase (430 aa)
initn: 2427 init1: 2427 opt: 2427 Z-score: 2396.7 bits: 453.3 E(85289): 9.3e-127
Smith-Waterman score: 2427; 99.7% identity (100.0% similar) in 375 aa overlap (1-375:26-400)
10 20 30
pF1KB8 MELADVGAAASSQGVHDQVLPTPNASSRVIVHVDL
:::::::::::::::::::::::::::::::::::
XP_006 MEKLGVEPEEEGGGDDDEEDAEAWAMELADVGAAASSQGVHDQVLPTPNASSRVIVHVDL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 DCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVN
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 GEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB8 HVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKP
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB8 NQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGI
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB8 SVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCTSEVEAKNKIEELLASLLNRVCQD
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_006 SVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB8 GRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTGNYDVMTPMVDILMKLFRNMV
::::::::::::::::::::::::::::::::::::::::
XP_006 GRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTGLQSPDFCASSLMQRRLEDKL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB8 NVKMPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLSTTSRSGKHSFKMKDTHMEDFPK
XP_006 VKLEGVFTKH
430
>>XP_005258249 (OMIM: 605252) PREDICTED: DNA polymerase (401 aa)
initn: 2419 init1: 2419 opt: 2419 Z-score: 2389.3 bits: 451.8 E(85289): 2.4e-126
Smith-Waterman score: 2419; 99.7% identity (100.0% similar) in 374 aa overlap (1-374:26-399)
10 20 30
pF1KB8 MELADVGAAASSQGVHDQVLPTPNASSRVIVHVDL
:::::::::::::::::::::::::::::::::::
XP_005 MEKLGVEPEEEGGGDDDEEDAEAWAMELADVGAAASSQGVHDQVLPTPNASSRVIVHVDL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 DCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVN
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 GEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB8 HVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKP
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB8 NQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQQTVLLPESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGI
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB8 SVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCTSEVEAKNKIEELLASLLNRVCQD
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_005 SVAQRIQKLSFGEDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQD
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB8 GRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTGNYDVMTPMVDILMKLFRNMV
:::::::::::::::::::::::::::::::::::::::
XP_005 GRKPHTVRLIIRRYSSEKHYGRESRQCPIPSHVIQKLGTEL
370 380 390 400
400 410 420 430 440 450
pF1KB8 NVKMPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLSTTSRSGKHSFKMKDTHMEDFPK
>>XP_011541769 (OMIM: 605650) PREDICTED: DNA polymerase (794 aa)
initn: 358 init1: 237 opt: 320 Z-score: 318.5 bits: 69.6 E(85289): 5.3e-11
Smith-Waterman score: 413; 23.4% identity (52.1% similar) in 691 aa overlap (27-636:10-677)
10 20 30 40 50 60
pF1KB8 MELADVGAAASSQGVHDQVLPTPNASSRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQK
: .:::.:.: ::: ::: .::::::::..: .
XP_011 MELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSM
10 20 30 40
70 80 90 100 110 120
pF1KB8 YLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVV
.. : ::.::..::. : ::. ::::..: .. .:: .: .: :.: ...:
XP_011 SMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVP-PNFDKYRAVSKEVKEILADYDPNF
50 60 70 80 90 100
130 140 150 160
pF1KB8 ERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSGHVYNN-------QSINLLD------
...:: ....:. .:.: . .. . . ... : :. .::.. :
XP_011 MAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDLQNLYIQRSITFTDNPGKEV
110 120 130 140 150 160
170 180
pF1KB8 ----------------------------------------VLHIRLLVGS---QIAAEMR
.:. .. :. ... :.:
XP_011 NKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVVKEIR
170 180 190 200 210 220
190 200 210 220 230 240
pF1KB8 EAMYNQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLP--ESCQHLIHSLNHIKEIPGI
. .. ::. ::.: : .:::. : ::: : .:: .. . .:..: :... ::
XP_011 FRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLP-IRKVSGI
230 240 250 260 270 280
250 260 270 280 290 300
pF1KB8 GYKTAKCLEALGINSVRDLQTFSPKILEKELGISVA-QRIQKLSFGEDNSPVILSGPPQS
: : : :.:::: . .: .. . : . : .. . . ..:.: .. . .: .:
XP_011 GKVTEKMLKALGIITCTEL--YQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKS
290 300 310 320 330
310 320 330 340 350 360
pF1KB8 FSEEDSFKKCTSEVEAKNKIEELLASLLNRVCQDGRKPHTVRLIIRRYSSEKHYGRESRQ
.: : .:.. .. : . .:: . : . . .. : .:: . .. . : . : :
XP_011 MSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKT-RASTV
340 350 360 370 380 390
370 380 390 400
pF1KB8 CPIPSH------VIQKLGTGNYDVMTP------MVDILMKLFRNMVNVKMPFHLTLLSVC
. : . ..: . :. : .. . .. : : . : . ....
XP_011 SSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEEDRKHQ-QRSIIGFL
400 410 420 430 440 450
410 420 430 440 450 460
pF1KB8 FCNLKALN----TAKKGLIDYYLMPSLSTTSRS--GKHSFKMKDTHMEDFPKDKETNRDF
. .::. : .: : .. : . ..: :. . : .:.. : . ....:
XP_011 QAGNQALSATECTLEKTDKDKFVKPLEMSHKKSFFDKKRSERKWSHQDTFKCEAVNKQSF
460 470 480 490 500 510
470 480 490 500 510 520
pF1KB8 LPSGRIESTRTRESP-LDTTNFSKEKDINEFPLCSLPEGVDQEVSKQLPVDIQEEILSGK
: .. . . . :. .. : . .: :.: .: . . . :: : :.:
XP_011 QTSQPFQVLKKKMNENLEISENSDDCQILTCPVCFRAQGCISLEALNKHVD---ECLDGP
520 530 540 550 560 570
530 540 550 560 570
pF1KB8 S-REKFQ--GKGSVSCPLHASRGVLSFFSKKQMQDIPINPRDHLSSSKQVSSVSPCEPGT
: :.:. . . :: .. . : . :: .:. :..:::. : .
XP_011 SISENFKMFSCSHVSATKVNKKENVPASSLCEKQDYEAHPK-----IKEISSVD-CIALV
580 590 600 610 620
580 590 600 610 620 630
pF1KB8 SGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFHSFPNLQS
. ...::.. . :.:. . :. :. :. ..:.. . . :. :. :
XP_011 DTIDNSSKA------ESIDALSNKHSKEECSSLPS--KSFNIEHCHQNSSSTVSLENEDV
630 640 650 660 670 680
640 650 660 670 680 690
pF1KB8 EQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKITFPSDIDPQVFYELPEAVQKEL
XP_011 GSFRQEYRQPYLCEVKTGQALVCPVCNVEQKTSDLTLFNVHVDVCLNKSFIQELRKDKFN
690 700 710 720 730 740
>>XP_016865050 (OMIM: 605650) PREDICTED: DNA polymerase (818 aa)
initn: 358 init1: 237 opt: 320 Z-score: 318.3 bits: 69.6 E(85289): 5.5e-11
Smith-Waterman score: 413; 23.4% identity (52.1% similar) in 691 aa overlap (27-636:34-701)
10 20 30 40 50
pF1KB8 MELADVGAAASSQGVHDQVLPTPNASSRVIVHVDLDCFYAQVEMISNPELKDKPLG
: .:::.:.: ::: ::: .::::::::..
XP_016 QKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 VQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEF
: . .. : ::.::..::. : ::. ::::..: .. .:: .: .: :.: ..
XP_016 VGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVP-PNFDKYRAVSKEVKEILADY
70 80 90 100 110 120
120 130 140 150 160
pF1KB8 SPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSGHVYNN-------QSINLLD--
.: ...:: ....:. .:.: . .. . . ... : :. .::.. :
XP_016 DPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDLQNLYIQRSITFTDNP
130 140 150 160 170 180
170 180
pF1KB8 --------------------------------------------VLHIRLLVGS---QIA
.:. .. :. ...
XP_016 GKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVV
190 200 210 220 230 240
190 200 210 220 230
pF1KB8 AEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLP--ESCQHLIHSLNHIKE
:.: . .. ::. ::.: : .:::. : ::: : .:: .. . .:..: :..
XP_016 KEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLP-IRK
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB8 IPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGISVA-QRIQKLSFGEDNSPVILSG
. ::: : : :.:::: . .: .. . : . : .. . . ..:.: .. . .:
XP_016 VSGIGKVTEKMLKALGIITCTEL--YQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDG
310 320 330 340 350
300 310 320 330 340 350
pF1KB8 PPQSFSEEDSFKKCTSEVEAKNKIEELLASLLNRVCQDGRKPHTVRLIIRRYSSEKHYGR
.:.: : .:.. .. : . .:: . : . . .. : .:: . .. . : . :
XP_016 ERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKT-R
360 370 380 390 400 410
360 370 380 390 400
pF1KB8 ESRQCPIPSH------VIQKLGTGNYDVMTP------MVDILMKLFRNMVNVKMPFHLTL
: . : . ..: . :. : .. . .. : : . : . ..
XP_016 ASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEEDRKHQ-QRSI
420 430 440 450 460 470
410 420 430 440 450
pF1KB8 LSVCFCNLKALN----TAKKGLIDYYLMPSLSTTSRS--GKHSFKMKDTHMEDFPKDKET
.. . .::. : .: : .. : . ..: :. . : .:.. : . .
XP_016 IGFLQAGNQALSATECTLEKTDKDKFVKPLEMSHKKSFFDKKRSERKWSHQDTFKCEAVN
480 490 500 510 520 530
460 470 480 490 500 510
pF1KB8 NRDFLPSGRIESTRTRESP-LDTTNFSKEKDINEFPLCSLPEGVDQEVSKQLPVDIQEEI
...: : .. . . . :. .. : . .: :.: .: . . . :: :
XP_016 KQSFQTSQPFQVLKKKMNENLEISENSDDCQILTCPVCFRAQGCISLEALNKHVD---EC
540 550 560 570 580 590
520 530 540 550 560 570
pF1KB8 LSGKS-REKFQ--GKGSVSCPLHASRGVLSFFSKKQMQDIPINPRDHLSSSKQVSSVSPC
:.: : :.:. . . :: .. . : . :: .:. :..:::. :
XP_016 LDGPSISENFKMFSCSHVSATKVNKKENVPASSLCEKQDYEAHPK-----IKEISSVD-C
600 610 620 630 640
580 590 600 610 620 630
pF1KB8 EPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFHSFP
.. ...::.. . :.:. . :. :. :. ..:.. . . :. :.
XP_016 IALVDTIDNSSKA------ESIDALSNKHSKEECSSLPS--KSFNIEHCHQNSSSTVSLE
650 660 670 680 690 700
640 650 660 670 680 690
pF1KB8 NLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKITFPSDIDPQVFYELPEAV
:
XP_016 NEDVGSFRQEYRQPYLCEVKTGQALVCPVCNVEQKTSDLTLFNVHVDVCLNKSFIQELRK
710 720 730 740 750 760
>>XP_011541765 (OMIM: 605650) PREDICTED: DNA polymerase (884 aa)
initn: 358 init1: 237 opt: 320 Z-score: 317.8 bits: 69.6 E(85289): 5.8e-11
Smith-Waterman score: 413; 23.4% identity (52.1% similar) in 691 aa overlap (27-636:100-767)
10 20 30 40 50
pF1KB8 MELADVGAAASSQGVHDQVLPTPNASSRVIVHVDLDCFYAQVEMISNPELKDKPLG
: .:::.:.: ::: ::: .::::::::..
XP_011 QKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIA
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB8 VQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEF
: . .. : ::.::..::. : ::. ::::..: .. .:: .: .: :.: ..
XP_011 VGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVP-PNFDKYRAVSKEVKEILADY
130 140 150 160 170 180
120 130 140 150 160
pF1KB8 SPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSGHVYNN-------QSINLLD--
.: ...:: ....:. .:.: . .. . . ... : :. .::.. :
XP_011 DPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDLQNLYIQRSITFTDNP
190 200 210 220 230 240
170 180
pF1KB8 --------------------------------------------VLHIRLLVGS---QIA
.:. .. :. ...
XP_011 GKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVV
250 260 270 280 290 300
190 200 210 220 230
pF1KB8 AEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLP--ESCQHLIHSLNHIKE
:.: . .. ::. ::.: : .:::. : ::: : .:: .. . .:..: :..
XP_011 KEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLP-IRK
310 320 330 340 350 360
240 250 260 270 280 290
pF1KB8 IPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGISVA-QRIQKLSFGEDNSPVILSG
. ::: : : :.:::: . .: .. . : . : .. . . ..:.: .. . .:
XP_011 VSGIGKVTEKMLKALGIITCTEL--YQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDG
370 380 390 400 410 420
300 310 320 330 340 350
pF1KB8 PPQSFSEEDSFKKCTSEVEAKNKIEELLASLLNRVCQDGRKPHTVRLIIRRYSSEKHYGR
.:.: : .:.. .. : . .:: . : . . .. : .:: . .. . : . :
XP_011 ERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKT-R
430 440 450 460 470 480
360 370 380 390 400
pF1KB8 ESRQCPIPSH------VIQKLGTGNYDVMTP------MVDILMKLFRNMVNVKMPFHLTL
: . : . ..: . :. : .. . .. : : . : . ..
XP_011 ASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEEDRKHQ-QRSI
490 500 510 520 530 540
410 420 430 440 450
pF1KB8 LSVCFCNLKALN----TAKKGLIDYYLMPSLSTTSRS--GKHSFKMKDTHMEDFPKDKET
.. . .::. : .: : .. : . ..: :. . : .:.. : . .
XP_011 IGFLQAGNQALSATECTLEKTDKDKFVKPLEMSHKKSFFDKKRSERKWSHQDTFKCEAVN
550 560 570 580 590 600
460 470 480 490 500 510
pF1KB8 NRDFLPSGRIESTRTRESP-LDTTNFSKEKDINEFPLCSLPEGVDQEVSKQLPVDIQEEI
...: : .. . . . :. .. : . .: :.: .: . . . :: :
XP_011 KQSFQTSQPFQVLKKKMNENLEISENSDDCQILTCPVCFRAQGCISLEALNKHVD---EC
610 620 630 640 650 660
520 530 540 550 560 570
pF1KB8 LSGKS-REKFQ--GKGSVSCPLHASRGVLSFFSKKQMQDIPINPRDHLSSSKQVSSVSPC
:.: : :.:. . . :: .. . : . :: .:. :..:::. :
XP_011 LDGPSISENFKMFSCSHVSATKVNKKENVPASSLCEKQDYEAHPK-----IKEISSVD-C
670 680 690 700 710
580 590 600 610 620 630
pF1KB8 EPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFHSFP
.. ...::.. . :.:. . :. :. :. ..:.. . . :. :.
XP_011 IALVDTIDNSSKA------ESIDALSNKHSKEECSSLPS--KSFNIEHCHQNSSSTVSLE
720 730 740 750 760
640 650 660 670 680 690
pF1KB8 NLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKITFPSDIDPQVFYELPEAV
:
XP_011 NEDVGSFRQEYRQPYLCEVKTGQALVCPVCNVEQKTSDLTLFNVHVDVCLNKSFIQELRK
770 780 790 800 810 820
>>XP_011541766 (OMIM: 605650) PREDICTED: DNA polymerase (884 aa)
initn: 358 init1: 237 opt: 320 Z-score: 317.8 bits: 69.6 E(85289): 5.8e-11
Smith-Waterman score: 413; 23.4% identity (52.1% similar) in 691 aa overlap (27-636:100-767)
10 20 30 40 50
pF1KB8 MELADVGAAASSQGVHDQVLPTPNASSRVIVHVDLDCFYAQVEMISNPELKDKPLG
: .:::.:.: ::: ::: .::::::::..
XP_011 QKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIA
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB8 VQQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQLVLVNGEDLTRYREMSYKVTELLEEF
: . .. : ::.::..::. : ::. ::::..: .. .:: .: .: :.: ..
XP_011 VGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVP-PNFDKYRAVSKEVKEILADY
130 140 150 160 170 180
120 130 140 150 160
pF1KB8 SPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSGHVYNN-------QSINLLD--
.: ...:: ....:. .:.: . .. . . ... : :. .::.. :
XP_011 DPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDLQNLYIQRSITFTDNP
190 200 210 220 230 240
170 180
pF1KB8 --------------------------------------------VLHIRLLVGS---QIA
.:. .. :. ...
XP_011 GKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVV
250 260 270 280 290 300
190 200 210 220 230
pF1KB8 AEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLP--ESCQHLIHSLNHIKE
:.: . .. ::. ::.: : .:::. : ::: : .:: .. . .:..: :..
XP_011 KEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLP-IRK
310 320 330 340 350 360
240 250 260 270 280 290
pF1KB8 IPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGISVA-QRIQKLSFGEDNSPVILSG
. ::: : : :.:::: . .: .. . : . : .. . . ..:.: .. . .:
XP_011 VSGIGKVTEKMLKALGIITCTEL--YQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDG
370 380 390 400 410 420
300 310 320 330 340 350
pF1KB8 PPQSFSEEDSFKKCTSEVEAKNKIEELLASLLNRVCQDGRKPHTVRLIIRRYSSEKHYGR
.:.: : .:.. .. : . .:: . : . . .. : .:: . .. . : . :
XP_011 ERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKT-R
430 440 450 460 470 480
360 370 380 390 400
pF1KB8 ESRQCPIPSH------VIQKLGTGNYDVMTP------MVDILMKLFRNMVNVKMPFHLTL
: . : . ..: . :. : .. . .. : : . : . ..
XP_011 ASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEEDRKHQ-QRSI
490 500 510 520 530 540
410 420 430 440 450
pF1KB8 LSVCFCNLKALN----TAKKGLIDYYLMPSLSTTSRS--GKHSFKMKDTHMEDFPKDKET
.. . .::. : .: : .. : . ..: :. . : .:.. : . .
XP_011 IGFLQAGNQALSATECTLEKTDKDKFVKPLEMSHKKSFFDKKRSERKWSHQDTFKCEAVN
550 560 570 580 590 600
460 470 480 490 500 510
pF1KB8 NRDFLPSGRIESTRTRESP-LDTTNFSKEKDINEFPLCSLPEGVDQEVSKQLPVDIQEEI
...: : .. . . . :. .. : . .: :.: .: . . . :: :
XP_011 KQSFQTSQPFQVLKKKMNENLEISENSDDCQILTCPVCFRAQGCISLEALNKHVD---EC
610 620 630 640 650 660
520 530 540 550 560 570
pF1KB8 LSGKS-REKFQ--GKGSVSCPLHASRGVLSFFSKKQMQDIPINPRDHLSSSKQVSSVSPC
:.: : :.:. . . :: .. . : . :: .:. :..:::. :
XP_011 LDGPSISENFKMFSCSHVSATKVNKKENVPASSLCEKQDYEAHPK-----IKEISSVD-C
670 680 690 700 710
580 590 600 610 620 630
pF1KB8 EPGTSGFNSSSSSYMSSQKDYSYYLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFHSFP
.. ...::.. . :.:. . :. :. :. ..:.. . . :. :.
XP_011 IALVDTIDNSSKA------ESIDALSNKHSKEECSSLPS--KSFNIEHCHQNSSSTVSLE
720 730 740 750 760
640 650 660 670 680 690
pF1KB8 NLQSEQLFSRNHTTDSHKQTVATDSHEGLTENREPDSVDEKITFPSDIDPQVFYELPEAV
:
XP_011 NEDVGSFRQEYRQPYLCEVKTGQALVCPVCNVEQKTSDLTLFNVHVDVCLNKSFIQELRK
770 780 790 800 810 820
715 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:38:05 2016 done: Fri Nov 4 12:38:06 2016
Total Scan time: 11.730 Total Display time: 0.170
Function used was FASTA [36.3.4 Apr, 2011]