Result of FASTA (omim) for
pF1KB8385
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8385, 423 aa
1>>>pF1KB8385 423 - 423 aa - 423 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9491+/-0.000393; mu= 8.9587+/- 0.025
mean_var=262.3473+/-53.256, 0's: 0 Z-trim(122.2): 399 B-trim: 648 in 1/54
Lambda= 0.079184
statistics sampled from 39581 (39994) to 39581 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.774), E-opt: 0.2 (0.469), width: 16
Scan time: 10.110
The best scores are: opt bits E(85289)
NP_005645 (OMIM: 132890,615722) COUP transcription ( 423) 2937 348.4 2.1e-95
NP_066285 (OMIM: 107773,615779) COUP transcription ( 414) 2459 293.8 5.5e-79
XP_016865286 (OMIM: 132890,615722) PREDICTED: COUP ( 273) 1796 217.8 2.7e-56
NP_001138627 (OMIM: 107773,615779) COUP transcript ( 281) 1713 208.3 2e-53
NP_001138629 (OMIM: 107773,615779) COUP transcript ( 261) 1672 203.6 4.8e-52
NP_001138628 (OMIM: 107773,615779) COUP transcript ( 261) 1672 203.6 4.8e-52
NP_005225 (OMIM: 132880) nuclear receptor subfamil ( 404) 1243 154.8 3.6e-37
NP_008848 (OMIM: 180247) retinoic acid receptor RX ( 463) 976 124.4 5.9e-28
NP_068811 (OMIM: 180246) retinoic acid receptor RX ( 533) 976 124.5 6.5e-28
XP_016866665 (OMIM: 180246) PREDICTED: retinoic ac ( 414) 973 124.0 7e-28
NP_001278849 (OMIM: 180245) retinoic acid receptor ( 435) 972 123.9 7.8e-28
NP_002948 (OMIM: 180245) retinoic acid receptor RX ( 462) 972 123.9 8.1e-28
NP_001257330 (OMIM: 180246) retinoic acid receptor ( 537) 973 124.1 8.3e-28
XP_011513098 (OMIM: 180246) PREDICTED: retinoic ac ( 420) 969 123.6 9.7e-28
NP_001278850 (OMIM: 180245) retinoic acid receptor ( 365) 964 122.9 1.3e-27
NP_001243500 (OMIM: 180247) retinoic acid receptor ( 340) 953 121.6 3e-27
NP_001243499 (OMIM: 180247) retinoic acid receptor ( 340) 953 121.6 3e-27
XP_005249335 (OMIM: 180246) PREDICTED: retinoic ac ( 441) 947 121.1 5.7e-27
NP_001278918 (OMIM: 180246) retinoic acid receptor ( 347) 922 118.1 3.6e-26
NP_001274111 (OMIM: 125850,125853,600281,616026) h ( 439) 796 103.8 8.9e-22
NP_001274112 (OMIM: 125850,125853,600281,616026) h ( 449) 796 103.8 9e-22
NP_001245284 (OMIM: 125850,125853,600281,616026) h ( 467) 787 102.8 1.9e-21
XP_005260464 (OMIM: 125850,125853,600281,616026) P ( 513) 787 102.9 2e-21
NP_849180 (OMIM: 125850,125853,600281,616026) hepa ( 464) 786 102.7 2e-21
NP_000448 (OMIM: 125850,125853,600281,616026) hepa ( 474) 786 102.7 2.1e-21
NP_001025174 (OMIM: 125850,125853,600281,616026) h ( 442) 785 102.6 2.1e-21
NP_001274113 (OMIM: 125850,125853,600281,616026) h ( 392) 784 102.4 2.1e-21
NP_787110 (OMIM: 125850,125853,600281,616026) hepa ( 452) 785 102.6 2.2e-21
NP_849181 (OMIM: 125850,125853,600281,616026) hepa ( 417) 774 101.3 4.9e-21
NP_001025175 (OMIM: 125850,125853,600281,616026) h ( 395) 773 101.1 5.1e-21
XP_016868863 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 764 100.1 1.1e-20
XP_016868865 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 764 100.1 1.1e-20
XP_016868862 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 764 100.1 1.1e-20
XP_016868864 (OMIM: 605966) PREDICTED: hepatocyte ( 408) 764 100.1 1.1e-20
NP_001317490 (OMIM: 605966) hepatocyte nuclear fac ( 408) 764 100.1 1.1e-20
NP_004124 (OMIM: 605966) hepatocyte nuclear factor ( 445) 764 100.2 1.1e-20
XP_016876575 (OMIM: 602167,608565) PREDICTED: ster ( 508) 675 90.1 1.4e-17
NP_004443 (OMIM: 602167,608565) steroid hormone re ( 508) 675 90.1 1.4e-17
XP_011534856 (OMIM: 602167,608565) PREDICTED: ster ( 529) 675 90.1 1.4e-17
XP_011534855 (OMIM: 602167,608565) PREDICTED: ster ( 531) 675 90.1 1.5e-17
XP_016876574 (OMIM: 602167,608565) PREDICTED: ster ( 552) 675 90.1 1.5e-17
XP_011534852 (OMIM: 602167,608565) PREDICTED: ster ( 552) 675 90.1 1.5e-17
XP_011534849 (OMIM: 602167,608565) PREDICTED: ster ( 573) 675 90.1 1.5e-17
NP_001230448 (OMIM: 602969) estrogen-related recep ( 435) 672 89.6 1.6e-17
XP_016856132 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 672 89.6 1.6e-17
XP_016856138 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 672 89.6 1.6e-17
XP_016856130 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 672 89.6 1.6e-17
XP_016856127 (OMIM: 602969) PREDICTED: estrogen-re ( 435) 672 89.6 1.6e-17
NP_001230444 (OMIM: 602969) estrogen-related recep ( 435) 672 89.6 1.6e-17
NP_001230442 (OMIM: 602969) estrogen-related recep ( 435) 672 89.6 1.6e-17
>>NP_005645 (OMIM: 132890,615722) COUP transcription fac (423 aa)
initn: 2937 init1: 2937 opt: 2937 Z-score: 1834.0 bits: 348.4 E(85289): 2.1e-95
Smith-Waterman score: 2937; 100.0% identity (100.0% similar) in 423 aa overlap (1-423:1-423)
10 20 30 40 50 60
pF1KB8 MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSI
370 380 390 400 410 420
pF1KB8 QCS
:::
NP_005 QCS
>>NP_066285 (OMIM: 107773,615779) COUP transcription fac (414 aa)
initn: 2271 init1: 2271 opt: 2459 Z-score: 1539.0 bits: 293.8 E(85289): 5.5e-79
Smith-Waterman score: 2459; 85.9% identity (90.8% similar) in 426 aa overlap (1-421:1-414)
10 20 30 40 50 60
pF1KB8 MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGA
::::::.::::::.: ::. . :. : : ::::::::::: :
NP_066 MAMVVSTWRDPQDEV----PGSQGSQASQAPPVPGPP--------PGAPHTPQTPGQGGP
10 20 30 40
70 80 90 100 110
pF1KB8 PATPGTAGDKGQGPPGSG-----QSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVR
.::. .. ::: ::. :.:::::::::::::::::::::::::::::::::::
NP_066 ASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB8 RNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTN
:::.:::::::::::::::::::::::::::::::::::::::::::::::. ::.::::
NP_066 RNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTN
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB8 GDPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWAR
::::: : :::::::::::::::::::.::::::::::::::::::::::.:::::::::
NP_066 GDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWAR
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB8 NIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAF
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::
NP_066 NIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAF
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB8 MDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEY
::::::::::::::::::::::::::::::::::::::::::.::.::::::::::::::
NP_066 MDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEY
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB8 VRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNW
:::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 VRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNW
350 360 370 380 390 400
420
pF1KB8 PYMSIQCS
:::.::
NP_066 PYMAIQ
410
>>XP_016865286 (OMIM: 132890,615722) PREDICTED: COUP tra (273 aa)
initn: 1796 init1: 1796 opt: 1796 Z-score: 1131.7 bits: 217.8 E(85289): 2.7e-56
Smith-Waterman score: 1796; 99.6% identity (100.0% similar) in 269 aa overlap (155-423:5-273)
130 140 150 160 170 180
pF1KB8 NRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCY
.:::::::::::::::::::::::::::::
XP_016 MFGYSVQRGRMPPTQPNPGQYALTNGDPLNGHCY
10 20 30
190 200 210 220 230 240
pF1KB8 LSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQ
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB8 ITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQE
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB8 QVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQP
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB8 SRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS
220 230 240 250 260 270
>>NP_001138627 (OMIM: 107773,615779) COUP transcription (281 aa)
initn: 1711 init1: 1711 opt: 1713 Z-score: 1080.3 bits: 208.3 E(85289): 2e-53
Smith-Waterman score: 1713; 93.5% identity (97.1% similar) in 275 aa overlap (147-421:7-281)
120 130 140 150 160 170
pF1KB8 NLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNG
:. : ::::::::::::. ::.:::::
NP_001 MQAVWDLEQGKYGFAVQRGRMPPTQPTHGQFALTNG
10 20 30
180 190 200 210 220 230
pF1KB8 DPLNGHCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARN
:::: : :::::::::::::::::::.::::::::::::::::::::::.::::::::::
NP_001 DPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARN
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB8 IPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFM
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFM
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB8 DHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYV
:::::::::::::::::::::::::::::::::::::::::.::.:::::::::::::::
NP_001 DHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYV
160 170 180 190 200 210
360 370 380 390 400 410
pF1KB8 RSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWP
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWP
220 230 240 250 260 270
420
pF1KB8 YMSIQCS
::.::
NP_001 YMAIQ
280
>>NP_001138629 (OMIM: 107773,615779) COUP transcription (261 aa)
initn: 1672 init1: 1672 opt: 1672 Z-score: 1055.3 bits: 203.6 E(85289): 4.8e-52
Smith-Waterman score: 1672; 95.4% identity (98.9% similar) in 261 aa overlap (161-421:1-261)
140 150 160 170 180 190
pF1KB8 DQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYIS
::::::. ::.::::::::: : :::::::
NP_001 MPPTQPTHGQFALTNGDPLNCHSYLSGYIS
10 20 30
200 210 220 230 240 250
pF1KB8 LLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVS
::::::::::::.::::::::::::::::::::::.:::::::::::::::::::::::.
NP_001 LLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVA
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB8 LLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLK
100 110 120 130 140 150
320 330 340 350 360 370
pF1KB8 ALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKL
:::::::::::::::::::::::::::.::.:::::::::::::::::::::::.:::::
NP_001 ALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKL
160 170 180 190 200 210
380 390 400 410 420
pF1KB8 LLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS
::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 LLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
220 230 240 250 260
>>NP_001138628 (OMIM: 107773,615779) COUP transcription (261 aa)
initn: 1672 init1: 1672 opt: 1672 Z-score: 1055.3 bits: 203.6 E(85289): 4.8e-52
Smith-Waterman score: 1672; 95.4% identity (98.9% similar) in 261 aa overlap (161-421:1-261)
140 150 160 170 180 190
pF1KB8 DQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNGHCYLSGYIS
::::::. ::.::::::::: : :::::::
NP_001 MPPTQPTHGQFALTNGDPLNCHSYLSGYIS
10 20 30
200 210 220 230 240 250
pF1KB8 LLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVS
::::::::::::.::::::::::::::::::::::.:::::::::::::::::::::::.
NP_001 LLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVA
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB8 LLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLK
100 110 120 130 140 150
320 330 340 350 360 370
pF1KB8 ALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKL
:::::::::::::::::::::::::::.::.:::::::::::::::::::::::.:::::
NP_001 ALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKL
160 170 180 190 200 210
380 390 400 410 420
pF1KB8 LLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS
::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_001 LLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
220 230 240 250 260
>>NP_005225 (OMIM: 132880) nuclear receptor subfamily 2 (404 aa)
initn: 1698 init1: 1089 opt: 1243 Z-score: 788.3 bits: 154.8 E(85289): 3.6e-37
Smith-Waterman score: 1713; 64.2% identity (82.0% similar) in 405 aa overlap (32-421:9-404)
10 20 30 40 50
pF1KB8 AMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQ--TPGQPG
:: :: . ..:: : :.. . . . ::
NP_005 MAMVTGGWGGPGGDTNGVDKAG-GYPRAAEDDSASPPG
10 20 30
60 70 80 90 100 110
pF1KB8 APATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLT
: :. . ::. . :: ...:::::::::::::: :::::::::::::.::::.
NP_005 A-ASDAEPGDEER--PG-----LQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLS
40 50 60 70 80
120 130 140 150 160 170
pF1KB8 YTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPN---------PGQ
::::.::.: :::::::::::::::::..::::.:::::::.: . :. ::.
NP_005 YTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGS
90 100 110 120 130 140
180 190 200 210 220
pF1KB8 Y--ALTNGDPLNGHCYLSGYISLLLRAEPYPTS--RYGSQCMQPNNIMGIENICELAARL
:...: : .: :. ::::::::.. :.:. . ..::.:.:::::::
NP_005 ALAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARL
150 160 170 180 190 200
230 240 250 260 270 280
pF1KB8 LFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASP
:::.:::::. ::::.: ..:::.::::.::::::::::: ..:::.:::::::::::.:
NP_005 LFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAP
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB8 MSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQE
:.:.:.:::::..: :::::.:: :.::::::.:::::.::: ::::::: ::.:::::
NP_005 MAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQE
270 280 290 300 310 320
350 360 370 380 390 400
pF1KB8 KSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDM
:.: :: ::::.:::.::.:::.::::::.::.: .:.: ::::.:::::::::::::::
NP_005 KAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDM
330 340 350 360 370 380
410 420
pF1KB8 LLSGSSFNWPYMSIQCS
:::::.::::: : :
NP_005 LLSGSTFNWPYGSGQ
390 400
>>NP_008848 (OMIM: 180247) retinoic acid receptor RXR-ga (463 aa)
initn: 793 init1: 392 opt: 976 Z-score: 622.8 bits: 124.4 E(85289): 5.9e-28
Smith-Waterman score: 976; 40.0% identity (67.3% similar) in 413 aa overlap (11-407:53-456)
10 20 30
pF1KB8 MAMVVSSWRDPQDDVAGGNP----GGPNPAAQAARGGGGG
:. : :.: :.: . .: : .:
NP_008 GSTSMSPSAALSTGKPMDSHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPPSG
30 40 50 60 70 80
40 50 60 70 80
pF1KB8 AGEQQQQAGSGAPHTPQ------TPGQPGAPATPGTAGDKGQGPPGS--GQSQQHIECVV
: . :: . : . .. :: : ... :.. :. .:: :..
NP_008 ALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHI-CAI
90 100 110 120 130 140
90 100 110 120 130 140
pF1KB8 CGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLK
:::.::::::: ..:::::.::::..:..: :::: :..: ::...::.::::: .:::
NP_008 CGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLV
150 160 170 180 190 200
150 160 170 180 190 200
pF1KB8 VGMRREAVQ--RGRMPPTQPNPGQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSRYGSQ
.::.::::: : : . .. : .. . . . : . ... :: : ::..
NP_008 MGMKREAVQEERQRSRERAESEAECATSGHEDMPVERILEAELAV----EP-KTESYGDM
210 220 230 240 250
210 220 230 240 250 260
pF1KB8 CMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQ
:. .. . :::. : . ::. ::::. :: : :: . ::: ::: :.::.. . ..
NP_008 NMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSH
260 270 280 290 300 310
270 280 290 300 310 320
pF1KB8 CSMPLHVAPLLAAAGLHASPMSADR--VVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKA
:. .. . :::. :::. :: : ...: :.. : : :.: ...:..: .::.:
NP_008 RSVSVQDGILLAT-GLHVHRSSAHSAGVGSIFD--RVLTELVSKMKDMQMDKSELGCLRA
320 330 340 350 360 370
330 340 350 360 370 380
pF1KB8 IVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSV
::::. :: :::. ...:.:.:: .:: :....::.::.::.:::::::.::... .
NP_008 IVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKC
380 390 400 410 420 430
390 400 410 420
pF1KB8 IEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQCS
.:.::: .:.: :::.:.. .::
NP_008 LEHLFFFKLIGDTPIDTFLMEMLETPLQIT
440 450 460
>>NP_068811 (OMIM: 180246) retinoic acid receptor RXR-be (533 aa)
initn: 744 init1: 651 opt: 976 Z-score: 622.1 bits: 124.5 E(85289): 6.5e-28
Smith-Waterman score: 976; 39.6% identity (68.4% similar) in 396 aa overlap (18-407:141-526)
10 20 30 40
pF1KB8 MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSG
:.:: : :: : .: .. : .. .
NP_068 PSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPP---GFSGPVSSPQINSTVS
120 130 140 150 160
50 60 70 80 90 100
pF1KB8 APHTPQTPGQPGAPATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCK
: . : . : . :. : . :::. . ... :..:::.::::::: ..:::::
NP_068 LPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRL-CAICGDRSSGKHYGVYSCEGCK
170 180 190 200 210 220
110 120 130 140 150 160
pF1KB8 SFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRM-PPTQP
.::::..:..:::.:: :..: .:...::.::::: .::: .::.:::::. :. .
NP_068 GFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKD
230 240 250 260 270 280
170 180 190 200 210 220
pF1KB8 NPGQYALTNGDPLNGHCYLSGYISLLLRAEPY---PTSRYGSQCMQPNNIMGIENICELA
. :. : . . : . ... ... : . :: .::. . :::. :
NP_068 GDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGS-SPND--PVTNICQAA
290 300 310 320 330 340
230 240 250 260 270 280
pF1KB8 ARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLH
. ::. ::::. :: : .: . ::: ::: :.::.. . .. :. .. . :::. :::
NP_068 DKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLAT-GLH
350 360 370 380 390 400
290 300 310 320 330 340
pF1KB8 ASPMSADR--VVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHI
. :: : :..: :.. : : :.. ...:..: .::.::.::. :: :::. ...
NP_068 VHRNSAHSAGVGAIFD--RVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEV
410 420 430 440 450 460
350 360 370 380 390 400
pF1KB8 ESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIET
: :.:: .:: : ...::.: .::.:::::::.::... . .:.::: .:.: :::.:
NP_068 EVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT
470 480 490 500 510 520
410 420
pF1KB8 LIRDMLLSGSSFNWPYMSIQCS
.. .::
NP_068 FLMEMLEAPHQLA
530
>>XP_016866665 (OMIM: 180246) PREDICTED: retinoic acid r (414 aa)
initn: 928 init1: 426 opt: 973 Z-score: 621.5 bits: 124.0 E(85289): 7e-28
Smith-Waterman score: 973; 39.4% identity (68.3% similar) in 398 aa overlap (18-407:18-407)
10 20 30 40 50 60
pF1KB8 MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGA
:.:: : :: : .: .. : .. . : . : .
XP_016 MPPPPLGSPFPVISSSMGSPGLPPPAPP---GFSGPVSSPQINSTVSLPGGGSGPPEDVK
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 PATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTY
: . :. : . :::. . ... :..:::.::::::: ..:::::.::::..:..:::
XP_016 PPVLGVRGLHCPPPPGGPGAGKRL-CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTY
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 TCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRM-PPTQPNPGQYALTNGDPL
.:: :..: .:...::.::::: .::: .::.:::::. :. . . :. : . .
XP_016 SCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEM
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 NGHCYLSGYISLLLRAEPY---PTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARN
: . ... ... : . :: .::. . :::. : . ::. ::::.
XP_016 PVDRILEAELAVEQKSDQGVEGPGGTGGSGS-SPND--PVTNICQAADKQLFTLVEWAKR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 IPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADR--VVA
:: : .: . ::: ::: :.::.. . .. :. .. . :::. :::. :: : :
XP_016 IPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLAT-GLHVHRNSAHSAGVGA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 FMDHI--RIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCAL
..:. :.. : : :.. ...:..: .::.::.::. :: :::. ...: :.:: .:
XP_016 IFDRSLSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASL
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB8 EEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSS
: : ...::.: .::.:::::::.::... . .:.::: .:.: :::.:.. .::
XP_016 ETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQ
360 370 380 390 400 410
420
pF1KB8 FNWPYMSIQCS
XP_016 LA
423 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:27:13 2016 done: Fri Nov 4 12:27:14 2016
Total Scan time: 10.110 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]