Result of FASTA (omim) for
pF1KB8378
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8378, 558 aa
1>>>pF1KB8378 558 - 558 aa - 558 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2218+/-0.00039; mu= 13.4634+/- 0.024
mean_var=85.1151+/-17.380, 0's: 0 Z-trim(113.6): 163 B-trim: 270 in 2/54
Lambda= 0.139018
statistics sampled from 22879 (23085) to 22879 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.271), width: 16
Scan time: 9.770
The best scores are: opt bits E(85289)
NP_705900 (OMIM: 605689) copine-7 isoform a [Homo ( 558) 3761 764.7 0
XP_011521302 (OMIM: 605689) PREDICTED: copine-7 is ( 595) 3453 702.9 7.1e-202
XP_016878629 (OMIM: 605689) PREDICTED: copine-7 is ( 599) 3435 699.3 8.7e-201
NP_055242 (OMIM: 605689) copine-7 isoform b [Homo ( 633) 2953 602.7 1.2e-171
XP_016878628 (OMIM: 605689) PREDICTED: copine-7 is ( 637) 2953 602.7 1.2e-171
XP_011521303 (OMIM: 605689) PREDICTED: copine-7 is ( 527) 2645 540.8 3.9e-153
XP_016878627 (OMIM: 605689) PREDICTED: copine-7 is ( 670) 2645 540.9 4.8e-153
NP_570720 (OMIM: 604208) copine-4 isoform 2 [Homo ( 557) 2625 536.8 6.6e-152
NP_001276041 (OMIM: 604208) copine-4 isoform 1 [Ho ( 575) 2625 536.9 6.7e-152
XP_016861182 (OMIM: 604208) PREDICTED: copine-4 is ( 575) 2625 536.9 6.7e-152
NP_702907 (OMIM: 604208) copine-4 isoform 1 [Homo ( 575) 2625 536.9 6.7e-152
XP_005268273 (OMIM: 605688) PREDICTED: copine-6 is ( 557) 2432 498.1 2.9e-140
NP_006023 (OMIM: 605688) copine-6 isoform 2 [Homo ( 557) 2432 498.1 2.9e-140
NP_001267487 (OMIM: 605688) copine-6 isoform 1 [Ho ( 612) 2432 498.2 3.2e-140
XP_011510709 (OMIM: 604208) PREDICTED: copine-4 is ( 444) 2230 457.6 3.8e-128
XP_011510708 (OMIM: 604208) PREDICTED: copine-4 is ( 444) 2230 457.6 3.8e-128
XP_011510710 (OMIM: 604208) PREDICTED: copine-4 is ( 444) 2230 457.6 3.8e-128
XP_016861183 (OMIM: 604208) PREDICTED: copine-4 is ( 434) 2029 417.3 5.1e-116
XP_016869434 (OMIM: 604207) PREDICTED: copine-3 is ( 537) 2027 416.9 8.1e-116
XP_005251150 (OMIM: 604207) PREDICTED: copine-3 is ( 537) 2027 416.9 8.1e-116
NP_003900 (OMIM: 604207) copine-3 [Homo sapiens] ( 537) 2027 416.9 8.1e-116
NP_689940 (OMIM: 604206) copine-2 [Homo sapiens] ( 548) 2015 414.5 4.4e-115
NP_690902 (OMIM: 604205) copine-1 isoform a [Homo ( 537) 1860 383.4 9.8e-106
NP_690903 (OMIM: 604205) copine-1 isoform a [Homo ( 537) 1860 383.4 9.8e-106
NP_690904 (OMIM: 604205) copine-1 isoform a [Homo ( 537) 1860 383.4 9.8e-106
NP_690905 (OMIM: 604205) copine-1 isoform a [Homo ( 537) 1860 383.4 9.8e-106
NP_003906 (OMIM: 604205) copine-1 isoform b [Homo ( 542) 1860 383.4 9.8e-106
NP_001185792 (OMIM: 604205) copine-1 isoform c [Ho ( 536) 1841 379.6 1.4e-104
XP_005268274 (OMIM: 605688) PREDICTED: copine-6 is ( 382) 1810 373.3 7.6e-103
XP_016878630 (OMIM: 605689) PREDICTED: copine-7 is ( 344) 1765 364.3 3.6e-100
XP_016861184 (OMIM: 604208) PREDICTED: copine-4 is ( 417) 1718 354.9 2.9e-97
XP_016861185 (OMIM: 604208) PREDICTED: copine-4 is ( 306) 1570 325.1 1.9e-88
NP_065990 (OMIM: 604209) copine-5 isoform a [Homo ( 593) 1375 286.2 2e-76
XP_005249304 (OMIM: 604209) PREDICTED: copine-5 is ( 610) 1366 284.4 7.3e-76
XP_011513071 (OMIM: 604209) PREDICTED: copine-5 is ( 653) 1269 264.9 5.6e-70
XP_016866628 (OMIM: 604209) PREDICTED: copine-5 is ( 522) 1260 263.1 1.6e-69
XP_011513072 (OMIM: 604209) PREDICTED: copine-5 is ( 632) 1260 263.1 1.9e-69
XP_011513073 (OMIM: 604209) PREDICTED: copine-5 is ( 632) 1260 263.1 1.9e-69
XP_011513070 (OMIM: 604209) PREDICTED: copine-5 is ( 670) 1260 263.1 2e-69
XP_011513075 (OMIM: 604209) PREDICTED: copine-5 is ( 473) 1235 258.0 4.7e-68
XP_011513074 (OMIM: 604209) PREDICTED: copine-5 is ( 543) 1095 230.0 1.5e-59
NP_001300947 (OMIM: 604209) copine-5 isoform c [Ho ( 301) 975 205.8 1.6e-52
XP_011513077 (OMIM: 604209) PREDICTED: copine-5 is ( 361) 869 184.6 4.7e-46
NP_001300948 (OMIM: 604209) copine-5 isoform d [Ho ( 243) 759 162.4 1.5e-39
NP_001300949 (OMIM: 604209) copine-5 isoform d [Ho ( 243) 759 162.4 1.5e-39
NP_001300946 (OMIM: 604209) copine-5 isoform b [Ho ( 140) 335 77.3 3.6e-14
NP_002730 (OMIM: 176980,605361) protein kinase C g ( 697) 183 47.1 0.00022
NP_001303258 (OMIM: 176980,605361) protein kinase ( 710) 183 47.1 0.00022
NP_997700 (OMIM: 176970) protein kinase C beta typ ( 671) 176 45.7 0.00056
NP_002729 (OMIM: 176970) protein kinase C beta typ ( 673) 176 45.7 0.00056
>>NP_705900 (OMIM: 605689) copine-7 isoform a [Homo sapi (558 aa)
initn: 3761 init1: 3761 opt: 3761 Z-score: 4079.6 bits: 764.7 E(85289): 0
Smith-Waterman score: 3761; 100.0% identity (100.0% similar) in 558 aa overlap (1-558:1-558)
10 20 30 40 50 60
pF1KB8 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 VAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 LYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 FIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 FIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 MGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 MGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 LGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 ARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 ARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDM
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 QVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 QVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGL
490 500 510 520 530 540
550
pF1KB8 PPRSLGVPAGEASPGCTP
::::::::::::::::::
NP_705 PPRSLGVPAGEASPGCTP
550
>>XP_011521302 (OMIM: 605689) PREDICTED: copine-7 isofor (595 aa)
initn: 3551 init1: 3453 opt: 3453 Z-score: 3745.3 bits: 702.9 E(85289): 7.1e-202
Smith-Waterman score: 3463; 91.6% identity (92.9% similar) in 580 aa overlap (1-556:1-578)
10 20 30 40 50 60
pF1KB8 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 FIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 MGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 ARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDM
430 440 450 460 470 480
490 500 510 520
pF1KB8 QVLDGDDGVLRSPRGEPALRDIVQFVPFRELKN-------------ASPAALAKCVLAE-
::::::::::::::::::::::::::::::::: :::.: : :.
XP_011 QVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNQRTAQGAPGIHHAASPVAANLCDPARH
490 500 510 520 530 540
530 540 550
pF1KB8 -----VPKQVVEYYSHRGLPPRSLGV-----PAGEASPGCTP
.: . . . :: : . :: :: : .:::
XP_011 AQHTRIPCGAGQVRAGRG-PEAGGGVLQPQRPAPE-KPGCPCRRGQPRLHTVKMWRA
550 560 570 580 590
>>XP_016878629 (OMIM: 605689) PREDICTED: copine-7 isofor (599 aa)
initn: 3492 init1: 3066 opt: 3435 Z-score: 3725.7 bits: 699.3 E(85289): 8.7e-201
Smith-Waterman score: 3445; 90.9% identity (92.3% similar) in 584 aa overlap (1-556:1-582)
10 20 30 40 50
pF1KB8 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQV-
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 ---GRTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQVGRTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 LGQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSD
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 PFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 GKHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSF
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 LDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDK
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 RFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPI
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 ISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNAD
430 440 450 460 470 480
480 490 500 510 520
pF1KB8 FTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKN-------------ASPAALAKCV
::::::::::::::::::::::::::::::::::::: :::.: :
XP_016 FTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNQRTAQGAPGIHHAASPVAANLCD
490 500 510 520 530 540
530 540 550
pF1KB8 LAE------VPKQVVEYYSHRGLPPRSLGV-----PAGEASPGCTP
:. .: . . . :: : . :: :: : .:::
XP_016 PARHAQHTRIPCGAGQVRAGRG-PEAGGGVLQPQRPAPE-KPGCPCRRGQPRLHTVKMWR
550 560 570 580 590
XP_016 A
>>NP_055242 (OMIM: 605689) copine-7 isoform b [Homo sapi (633 aa)
initn: 2953 init1: 2953 opt: 2953 Z-score: 3202.9 bits: 602.7 E(85289): 1.2e-171
Smith-Waterman score: 3310; 87.3% identity (87.3% similar) in 590 aa overlap (44-558:44-633)
20 30 40 50 60 70
pF1KB8 GGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVF
::::::::::::::::::::::::::::::
NP_055 GGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVF
20 30 40 50 60 70
80 90 100 110
pF1KB8 SKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ--------------
::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQPAQKWLLQVVMRVS
80 90 100 110 120 130
pF1KB8 ------------------------------------------------------------
NP_055 VDVLGPAGHCAKHFLCCTESSHLARTGPSFLLRYDDLCLPWATAGAVRWWTCRGGHTQGW
140 150 160 170 180 190
120 130 140 150 160 170
pF1KB8 -IVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF
200 210 220 230 240 250
180 190 200 210 220 230
pF1KB8 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK
260 270 280 290 300 310
240 250 260 270 280 290
pF1KB8 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD
320 330 340 350 360 370
300 310 320 330 340 350
pF1KB8 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF
380 390 400 410 420 430
360 370 380 390 400 410
pF1KB8 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS
440 450 460 470 480 490
420 430 440 450 460 470
pF1KB8 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT
500 510 520 530 540 550
480 490 500 510 520 530
pF1KB8 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR
560 570 580 590 600 610
540 550
pF1KB8 GLPPRSLGVPAGEASPGCTP
::::::::::::::::::::
NP_055 GLPPRSLGVPAGEASPGCTP
620 630
>--
initn: 291 init1: 291 opt: 291 Z-score: 317.5 bits: 68.8 E(85289): 6e-11
Smith-Waterman score: 291; 100.0% identity (100.0% similar) in 43 aa overlap (1-43:1-43)
10 20 30 40 50 60
pF1KB8 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG
:::::::::::::::::::::::::::::::::::::::::::
NP_055 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQI
NP_055 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQP
70 80 90 100 110 120
>>XP_016878628 (OMIM: 605689) PREDICTED: copine-7 isofor (637 aa)
initn: 3338 init1: 2953 opt: 2953 Z-score: 3202.9 bits: 602.7 E(85289): 1.2e-171
Smith-Waterman score: 3267; 86.6% identity (86.6% similar) in 590 aa overlap (48-558:48-637)
20 30 40 50 60 70
pF1KB8 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQV----GRTEVVRSSLHPVF
:::::::::::: ::::::::::::::
XP_016 APCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVHLQVGRTEVVRSSLHPVF
20 30 40 50 60 70
80 90 100 110
pF1KB8 SKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQPAQKWLLQVVMRVS
80 90 100 110 120 130
pF1KB8 ------------------------------------------------------------
XP_016 VDVLGPAGHCAKHFLCCTESSHLARTGPSFLLRYDDLCLPWATAGAVRWWTCRGGHTQGW
140 150 160 170 180 190
120 130 140 150 160 170
pF1KB8 -IVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF
200 210 220 230 240 250
180 190 200 210 220 230
pF1KB8 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK
260 270 280 290 300 310
240 250 260 270 280 290
pF1KB8 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD
320 330 340 350 360 370
300 310 320 330 340 350
pF1KB8 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF
380 390 400 410 420 430
360 370 380 390 400 410
pF1KB8 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS
440 450 460 470 480 490
420 430 440 450 460 470
pF1KB8 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT
500 510 520 530 540 550
480 490 500 510 520 530
pF1KB8 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHR
560 570 580 590 600 610
540 550
pF1KB8 GLPPRSLGVPAGEASPGCTP
::::::::::::::::::::
XP_016 GLPPRSLGVPAGEASPGCTP
620 630
>--
initn: 316 init1: 316 opt: 316 Z-score: 344.6 bits: 73.8 E(85289): 1.9e-12
Smith-Waterman score: 316; 100.0% identity (100.0% similar) in 47 aa overlap (1-47:1-47)
10 20 30 40 50 60
pF1KB8 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQI
XP_016 LQVGRTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECT
70 80 90 100 110 120
>>XP_011521303 (OMIM: 605689) PREDICTED: copine-7 isofor (527 aa)
initn: 2743 init1: 2645 opt: 2645 Z-score: 2870.3 bits: 540.8 E(85289): 3.9e-153
Smith-Waterman score: 2655; 89.4% identity (91.1% similar) in 462 aa overlap (119-556:51-510)
90 100 110 120 130 140
pF1KB8 LRFEVYDTHGPSGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGRNAGKSTITVIAE
::::::::::::::::::::::::::::::
XP_011 WGRYDDLCLPWATAGAVRWWTCRGGHTQGWQIVAQKKVTRPLLLKFGRNAGKSTITVIAE
30 40 50 60 70 80
150 160 170 180 190 200
pF1KB8 DISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWE
90 100 110 120 130 140
210 220 230 240 250 260
pF1KB8 AFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQWDCVNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQWDCVNP
150 160 170 180 190 200
270 280 290 300 310 320
pF1KB8 KYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLH
210 220 230 240 250 260
330 340 350 360 370 380
pF1KB8 YINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDEC
270 280 290 300 310 320
390 400 410 420 430 440
pF1KB8 EGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQYYILLILTDGVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQYYILLILTDGVVT
330 340 350 360 370 380
450 460 470 480 490 500
pF1KB8 DMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPF
390 400 410 420 430 440
510 520 530 540
pF1KB8 RELKN-------------ASPAALAKCVLAE------VPKQVVEYYSHRGLPPRSLGV--
::::: :::.: : :. .: . . . :: : . ::
XP_011 RELKNQRTAQGAPGIHHAASPVAANLCDPARHAQHTRIPCGAGQVRAGRG-PEAGGGVLQ
450 460 470 480 490
550
pF1KB8 ---PAGEASPGCTP
:: : .:::
XP_011 PQRPAPE-KPGCPCRRGQPRLHTVKMWRA
500 510 520
>>XP_016878627 (OMIM: 605689) PREDICTED: copine-7 isofor (670 aa)
initn: 3446 init1: 2645 opt: 2645 Z-score: 2868.7 bits: 540.9 E(85289): 4.8e-153
Smith-Waterman score: 3012; 79.7% identity (81.0% similar) in 612 aa overlap (44-556:44-653)
20 30 40 50 60 70
pF1KB8 GGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVF
::::::::::::::::::::::::::::::
XP_016 GGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVF
20 30 40 50 60 70
80 90 100 110
pF1KB8 SKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQ--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQPAQKWLLQVVMRVS
80 90 100 110 120 130
pF1KB8 ------------------------------------------------------------
XP_016 VDVLGPAGHCAKHFLCCTESSHLARTGPSFLLRYDDLCLPWATAGAVRWWTCRGGHTQGW
140 150 160 170 180 190
120 130 140 150 160 170
pF1KB8 -IVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPF
200 210 220 230 240 250
180 190 200 210 220 230
pF1KB8 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGK
260 270 280 290 300 310
240 250 260 270 280 290
pF1KB8 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLD
320 330 340 350 360 370
300 310 320 330 340 350
pF1KB8 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRF
380 390 400 410 420 430
360 370 380 390 400 410
pF1KB8 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIIS
440 450 460 470 480 490
420 430 440 450 460 470
pF1KB8 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFT
500 510 520 530 540 550
480 490 500 510 520
pF1KB8 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKN-------------ASPAALAKCVLA
::::::::::::::::::::::::::::::::::: :::.: : :
XP_016 DMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNQRTAQGAPGIHHAASPVAANLCDPA
560 570 580 590 600 610
530 540 550
pF1KB8 E------VPKQVVEYYSHRGLPPRSLGV-----PAGEASPGCTP
. .: . . . :: : . :: :: : .:::
XP_016 RHAQHTRIPCGAGQVRAGRG-PEAGGGVLQPQRPAPE-KPGCPCRRGQPRLHTVKMWRA
620 630 640 650 660 670
>--
initn: 291 init1: 291 opt: 291 Z-score: 317.1 bits: 68.8 E(85289): 6.3e-11
Smith-Waterman score: 291; 100.0% identity (100.0% similar) in 43 aa overlap (1-43:1-43)
10 20 30 40 50 60
pF1KB8 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG
:::::::::::::::::::::::::::::::::::::::::::
XP_016 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQI
XP_016 RTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQP
70 80 90 100 110 120
>>NP_570720 (OMIM: 604208) copine-4 isoform 2 [Homo sapi (557 aa)
initn: 2636 init1: 2159 opt: 2625 Z-score: 2848.2 bits: 536.8 E(85289): 6.6e-152
Smith-Waterman score: 2625; 70.5% identity (89.6% similar) in 536 aa overlap (9-543:11-543)
10 20 30 40 50
pF1KB8 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQ
:: : : . .:: .:::::..:. . ::: :.: :: : : .:..::: .
NP_570 MKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALSKPDPCVILKMQSHGQWFE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 VGRTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYD-THGPSGFSCQEDDFLGGMECTL
: ::::.:. ..::.::.::::.::::::::::::.: . . .:. .: ::::::::::
NP_570 VDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNHNGL--KEADFLGGMECTL
70 80 90 100 110
120 130 140 150 160 170
pF1KB8 GQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDP
::::.:.:... :: : : .::::.::::::..:::. ::::.: ::::::::.::::::
NP_570 GQIVSQRKLSKSLL-KHGNTAGKSSITVIAEELSGNDDYVELAFNARKLDDKDFFSKSDP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 FLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRG
:::..:.::: :::.::::: :::.:.:..::::..:::: . : :::.:::.:: :
NP_570 FLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCSGDPDRRLKCIVWDWDSNG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 KHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFL
::::::::..::.::. :.: :.::.:.::::: :...:::::.:.: :.:...:::
NP_570 KHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKNSGTVILNLCKIHKMHSFL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 DYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKR
:::::::::.:::::::::::::::::::::::.::::::::::::.::::::::::::
NP_570 DYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYLKALVAVGEICQDYDSDKM
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB8 FSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPII
: :.::::::::.: :::::::::: .. :: ::::::::::.:::..:::::::.::::
NP_570 FPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQSCLPKLQLYGPTNIAPII
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB8 SKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADF
.:::. :. : .: .::::.:::::::::.:::::::::::.::.::::.::::::::::
NP_570 QKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVHASHLPMSVIIVGVGNADF
420 430 440 450 460 470
480 490 500 510 520 530
pF1KB8 TDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSH
.:::.::::::.::::.:::.:::::::::::..:.:::::::: ::::::.:::.::.
NP_570 SDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAALAKSVLAEVPNQVVDYYNG
480 490 500 510 520 530
540 550
pF1KB8 RGLPPRSLGVPAGEASPGCTP
.:. :.
NP_570 KGIKPKCSSEMYESSRTLAP
540 550
>>NP_001276041 (OMIM: 604208) copine-4 isoform 1 [Homo s (575 aa)
initn: 2636 init1: 2159 opt: 2625 Z-score: 2848.0 bits: 536.9 E(85289): 6.7e-152
Smith-Waterman score: 2625; 70.5% identity (89.6% similar) in 536 aa overlap (9-543:29-561)
10 20 30 40
pF1KB8 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLT
:: : : . .:: .:::::..:. . ::: :.
NP_001 MAVEPSSSESIKRRAGRRMKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALS
10 20 30 40 50 60
50 60 70 80 90
pF1KB8 KSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYD-THGP
: :: : : .:..::: .: ::::.:. ..::.::.::::.::::::::::::.: . .
NP_001 KPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 SGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVEL
.:. .: ::::::::::::::.:.:... :: : : .::::.::::::..:::. ::::
NP_001 NGL--KEADFLGGMECTLGQIVSQRKLSKSLL-KHGNTAGKSSITVIAEELSGNDDYVEL
130 140 150 160 170
160 170 180 190 200 210
pF1KB8 SFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCS
.: ::::::::.:::::::::..:.::: :::.::::: :::.:.:..::::..::::
NP_001 AFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCS
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB8 CEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKN
. : :::.:::.:: :::::::::..::.::. :.: :.::.:.::::: :...:::
NP_001 GDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKN
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB8 SGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYL
::.:.: :.:...::::::::::::.:::::::::::::::::::::::.::::::::
NP_001 SGTVILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYL
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB8 KALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQ
::::.:::::::::::: : :.::::::::.: :::::::::: .. :: ::::::::::
NP_001 KALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQ
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB8 NCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVR
.:::..:::::::.::::.:::. :. : .: .::::.:::::::::.:::::::::::.
NP_001 SCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVH
420 430 440 450 460 470
460 470 480 490 500 510
pF1KB8 ASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAAL
::.::::.::::::::::.:::.::::::.::::.:::.:::::::::::..:.::::::
NP_001 ASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAAL
480 490 500 510 520 530
520 530 540 550
pF1KB8 AKCVLAEVPKQVVEYYSHRGLPPRSLGVPAGEASPGCTP
:: ::::::.:::.::. .:. :.
NP_001 AKSVLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
540 550 560 570
>>XP_016861182 (OMIM: 604208) PREDICTED: copine-4 isofor (575 aa)
initn: 2636 init1: 2159 opt: 2625 Z-score: 2848.0 bits: 536.9 E(85289): 6.7e-152
Smith-Waterman score: 2625; 70.5% identity (89.6% similar) in 536 aa overlap (9-543:29-561)
10 20 30 40
pF1KB8 MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLT
:: : : . .:: .:::::..:. . ::: :.
XP_016 MAVEPSSSESIKRRAGRRMKKMSNIYESAANTLGIFNSPCLTKVELRVACKGISDRDALS
10 20 30 40 50 60
50 60 70 80 90
pF1KB8 KSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYD-THGP
: :: : : .:..::: .: ::::.:. ..::.::.::::.::::::::::::.: . .
XP_016 KPDPCVILKMQSHGQWFEVDRTEVIRTCINPVYSKLFTVDFYFEEVQRLRFEVHDISSNH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 SGFSCQEDDFLGGMECTLGQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVEL
.:. .: ::::::::::::::.:.:... :: : : .::::.::::::..:::. ::::
XP_016 NGL--KEADFLGGMECTLGQIVSQRKLSKSLL-KHGNTAGKSSITVIAEELSGNDDYVEL
130 140 150 160 170
160 170 180 190 200 210
pF1KB8 SFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCS
.: ::::::::.:::::::::..:.::: :::.::::: :::.:.:..::::..::::
XP_016 AFNARKLDDKDFFSKSDPFLEIFRMNDDATQQLVHRTEVVMNNLSPAWKSFKVSVNSLCS
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB8 CEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKN
. : :::.:::.:: :::::::::..::.::. :.: :.::.:.::::: :...:::
XP_016 GDPDRRLKCIVWDWDSNGKHDFIGEFTSTFKEMRGAMEGKQVQWECINPKYKAKKKNYKN
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB8 SGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYL
::.:.: :.:...::::::::::::.:::::::::::::::::::::::.::::::::
XP_016 SGTVILNLCKIHKMHSFLDYIMGGCQIQFTVAIDFTASNGDPRNSCSLHYIHPYQPNEYL
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB8 KALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQ
::::.:::::::::::: : :.::::::::.: :::::::::: .. :: ::::::::::
XP_016 KALVAVGEICQDYDSDKMFPAFGFGARIPPEYTVSHDFAINFNEDNPECAGIQGVVEAYQ
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB8 NCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVR
.:::..:::::::.::::.:::. :. : .: .::::.:::::::::.:::::::::::.
XP_016 SCLPKLQLYGPTNIAPIIQKVAKSASEETNTKEASQYFILLILTDGVITDMADTREAIVH
420 430 440 450 460 470
460 470 480 490 500 510
pF1KB8 ASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAAL
::.::::.::::::::::.:::.::::::.::::.:::.:::::::::::..:.::::::
XP_016 ASHLPMSVIIVGVGNADFSDMQMLDGDDGILRSPKGEPVLRDIVQFVPFRNFKHASPAAL
480 490 500 510 520 530
520 530 540 550
pF1KB8 AKCVLAEVPKQVVEYYSHRGLPPRSLGVPAGEASPGCTP
:: ::::::.:::.::. .:. :.
XP_016 AKSVLAEVPNQVVDYYNGKGIKPKCSSEMYESSRTLAP
540 550 560 570
558 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:23:55 2016 done: Fri Nov 4 12:23:57 2016
Total Scan time: 9.770 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]