Result of FASTA (omim) for
pF1KB8352
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8352, 693 aa
1>>>pF1KB8352 693 - 693 aa - 693 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.9604+/-0.000429; mu= -13.8744+/- 0.027
mean_var=607.8393+/-133.160, 0's: 0 Z-trim(123.8): 97 B-trim: 0 in 0/61
Lambda= 0.052021
statistics sampled from 44050 (44179) to 44050 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.796), E-opt: 0.2 (0.518), width: 16
Scan time: 12.650
The best scores are: opt bits E(85289)
XP_005274725 (OMIM: 300283) PREDICTED: interleukin ( 708) 3471 275.8 3.8e-73
NP_001020413 (OMIM: 300283) interleukin-1 receptor ( 682) 2933 235.5 5.3e-61
NP_001560 (OMIM: 300283) interleukin-1 receptor-as ( 712) 2933 235.5 5.5e-61
NP_001020414 (OMIM: 300283) interleukin-1 receptor ( 633) 2665 215.3 5.8e-55
XP_011529460 (OMIM: 300283) PREDICTED: interleukin ( 603) 2663 215.1 6.2e-55
NP_001561 (OMIM: 603304) interleukin-1 receptor-as ( 625) 705 68.2 1.1e-10
NP_001135995 (OMIM: 604459,611064) interleukin-1 r ( 535) 586 59.2 4.8e-08
NP_009130 (OMIM: 604459,611064) interleukin-1 rece ( 596) 586 59.2 5.2e-08
NP_057207 (OMIM: 606883,607676,610799) interleukin ( 460) 475 50.8 1.4e-05
XP_005269002 (OMIM: 606883,607676,610799) PREDICTE ( 460) 475 50.8 1.4e-05
NP_001107654 (OMIM: 606883,607676,610799) interleu ( 460) 475 50.8 1.4e-05
XP_011536734 (OMIM: 606883,607676,610799) PREDICTE ( 460) 475 50.8 1.4e-05
XP_011536735 (OMIM: 606883,607676,610799) PREDICTE ( 460) 475 50.8 1.4e-05
XP_011536733 (OMIM: 606883,607676,610799) PREDICTE ( 460) 475 50.8 1.4e-05
XP_006719501 (OMIM: 606883,607676,610799) PREDICTE ( 460) 475 50.8 1.4e-05
XP_016874879 (OMIM: 606883,607676,610799) PREDICTE ( 460) 475 50.8 1.4e-05
XP_005269000 (OMIM: 606883,607676,610799) PREDICTE ( 460) 475 50.8 1.4e-05
XP_005269001 (OMIM: 606883,607676,610799) PREDICTE ( 460) 475 50.8 1.4e-05
XP_016874880 (OMIM: 606883,607676,610799) PREDICTE ( 336) 463 49.7 2.1e-05
XP_005269004 (OMIM: 606883,607676,610799) PREDICTE ( 336) 463 49.7 2.1e-05
XP_005269006 (OMIM: 606883,607676,610799) PREDICTE ( 336) 463 49.7 2.1e-05
XP_005269005 (OMIM: 606883,607676,610799) PREDICTE ( 336) 463 49.7 2.1e-05
NP_001138728 (OMIM: 606883,607676,610799) interleu ( 336) 463 49.7 2.1e-05
NP_001138730 (OMIM: 606883,607676,610799) interleu ( 336) 463 49.7 2.1e-05
NP_001138729 (OMIM: 606883,607676,610799) interleu ( 336) 463 49.7 2.1e-05
XP_006719502 (OMIM: 606883,607676,610799) PREDICTE ( 336) 463 49.7 2.1e-05
XP_006719505 (OMIM: 606883,607676,610799) PREDICTE ( 257) 449 48.6 3.6e-05
XP_006719504 (OMIM: 606883,607676,610799) PREDICTE ( 257) 449 48.6 3.6e-05
XP_006719503 (OMIM: 606883,607676,610799) PREDICTE ( 257) 449 48.6 3.6e-05
XP_006719506 (OMIM: 606883,607676,610799) PREDICTE ( 257) 449 48.6 3.6e-05
>>XP_005274725 (OMIM: 300283) PREDICTED: interleukin-1 r (708 aa)
initn: 3471 init1: 3471 opt: 3471 Z-score: 1434.1 bits: 275.8 E(85289): 3.8e-73
Smith-Waterman score: 4721; 97.9% identity (97.9% similar) in 708 aa overlap (1-693:1-708)
10 20 30 40 50 60
pF1KB8 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LAPTPDAPRPAAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAPTPDAPRPAAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQS
430 440 450 460 470 480
490 500 510 520
pF1KB8 TLQAGLAADAWAAPIAMQIYKKHL---------------GQLACCCLHRRAKRRPPMTQE
:::::::::::::::::::::::: :::::::::::::::::::::
XP_005 TLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQE
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB8 NSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHL
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB8 TPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINP
610 620 630 640 650 660
650 660 670 680 690
pF1KB8 ARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
670 680 690 700
>>NP_001020413 (OMIM: 300283) interleukin-1 receptor-ass (682 aa)
initn: 3268 init1: 2929 opt: 2933 Z-score: 1216.1 bits: 235.5 E(85289): 5.3e-61
Smith-Waterman score: 4470; 94.2% identity (94.2% similar) in 708 aa overlap (1-693:1-682)
10 20 30 40 50 60
pF1KB8 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGL
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQF---------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 LAPTPDAPRPAAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----------AALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
50 60 70 80 90
130 140 150 160 170 180
pF1KB8 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB8 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB8 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQS
400 410 420 430 440 450
490 500 510 520
pF1KB8 TLQAGLAADAWAAPIAMQIYKKHL---------------GQLACCCLHRRAKRRPPMTQE
:::::::::::::::::::::::: :::::::::::::::::::::
NP_001 TLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQE
460 470 480 490 500 510
530 540 550 560 570 580
pF1KB8 NSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHL
520 530 540 550 560 570
590 600 610 620 630 640
pF1KB8 TPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINP
580 590 600 610 620 630
650 660 670 680 690
pF1KB8 ARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
640 650 660 670 680
>>NP_001560 (OMIM: 300283) interleukin-1 receptor-associ (712 aa)
initn: 4411 init1: 2929 opt: 2933 Z-score: 1215.9 bits: 235.5 E(85289): 5.5e-61
Smith-Waterman score: 4309; 90.2% identity (90.2% similar) in 725 aa overlap (1-680:1-699)
10 20 30 40 50 60
pF1KB8 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGL
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQF---------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 LAPTPDAPRPAAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----------AALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
50 60 70 80 90
130 140 150 160 170 180
pF1KB8 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB8 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB8 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQS
400 410 420 430 440 450
490 500 510 520
pF1KB8 TLQAGLAADAWAAPIAMQIYKKHL---------------GQLACCCLHRRAKRRPPMTQ-
:::::::::::::::::::::::: ::::::::::::::::::::
NP_001 TLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQV
460 470 480 490 500 510
530 540 550
pF1KB8 -----------------------------ENSYVSSTGRAHSGAAPWQPLAAPSGASAQA
:::::::::::::::::::::::::::::::
NP_001 YERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQA
520 530 540 550 560 570
560 570 580 590 600 610
pF1KB8 AEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSG
580 590 600 610 620 630
620 630 640 650 660 670
pF1KB8 PGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPG
640 650 660 670 680 690
680 690
pF1KB8 LGLEQDRQGPEESDEFQS
:::::
NP_001 LGLEQDRQGPEESDEFQS
700 710
>>NP_001020414 (OMIM: 300283) interleukin-1 receptor-ass (633 aa)
initn: 4138 init1: 2656 opt: 2665 Z-score: 1107.8 bits: 215.3 E(85289): 5.8e-55
Smith-Waterman score: 4042; 88.7% identity (90.2% similar) in 693 aa overlap (1-693:1-633)
10 20 30 40 50 60
pF1KB8 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGL
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQF---------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 LAPTPDAPRPAAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----------AALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
50 60 70 80 90
130 140 150 160 170 180
pF1KB8 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB8 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB8 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQS
:::::::::::::::::::::::::::::::::::::::: : :. :.. :.
NP_001 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYL---VYER-------LEKLQA
400 410 420 430 440
490 500 510 520 530 540
pF1KB8 TLQAGLAADAWAAPIAMQIYKKHLGQLACCCLHRRAKRRPPMTQENSYVSSTGRAHSGAA
.. ::. . . :: :. :: :::::::::::::::::
NP_001 VV-AGVPGHSEAAS----------------CI-------PPSPQENSYVSSTGRAHSGAA
450 460 470 480
550 560 570 580 590 600
pF1KB8 PWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAG
490 500 510 520 530 540
610 620 630 640 650 660
pF1KB8 CPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDG
550 560 570 580 590 600
670 680 690
pF1KB8 ALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
:::::::::::::::::::::::::::::::::
NP_001 ALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
610 620 630
>>XP_011529460 (OMIM: 300283) PREDICTED: interleukin-1 r (603 aa)
initn: 3066 init1: 2659 opt: 2663 Z-score: 1107.2 bits: 215.1 E(85289): 6.2e-55
Smith-Waterman score: 3942; 87.0% identity (87.0% similar) in 693 aa overlap (1-693:1-603)
10 20 30 40 50 60
pF1KB8 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGL
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQF---------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 LAPTPDAPRPAAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -----------AALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
50 60 70 80 90
130 140 150 160 170 180
pF1KB8 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB8 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB8 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQS
::::::::::::::::::::::::::::::::::::::::
XP_011 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYL--------------------
400 410 420 430
490 500 510 520 530 540
pF1KB8 TLQAGLAADAWAAPIAMQIYKKHLGQLACCCLHRRAKRRPPMTQENSYVSSTGRAHSGAA
::::::::::::::::
XP_011 --------------------------------------------ENSYVSSTGRAHSGAA
440 450
550 560 570 580 590 600
pF1KB8 PWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAG
460 470 480 490 500 510
610 620 630 640 650 660
pF1KB8 CPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDG
520 530 540 550 560 570
670 680 690
pF1KB8 ALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
:::::::::::::::::::::::::::::::::
XP_011 ALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
580 590 600
>>NP_001561 (OMIM: 603304) interleukin-1 receptor-associ (625 aa)
initn: 648 init1: 194 opt: 705 Z-score: 312.9 bits: 68.2 E(85289): 1.1e-10
Smith-Waterman score: 787; 28.4% identity (55.3% similar) in 682 aa overlap (18-668:4-623)
10 20 30 40 50 60
pF1KB8 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGL
..:..: ::. . . :::: :: .:
NP_001 MACYIYQLPSWVLDDLCRNMDALSEWDWMEF---------------
10 20 30
70 80 90 100 110
pF1KB8 LAPTPDAPRPAAALIVRDQTELRLCERSGQRTASV------LWPWINRNARVADLVHILT
:. .. : :.:: .: .:. .: :: : :.: : .:: .:
NP_001 -----------ASYVITDLTQLRKI-KSMERVQGVSITRELLWWWGMRQATVQQLVDLLC
40 50 60 70
120 130 140 150 160
pF1KB8 HLQLLRARDIITAWHP-PA---PLPS-PGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFL
.:.: :: .:: :.: : :.:. : .. :. . .:: . . : .::
NP_001 RLELYRAAQIILNWKPAPEIRCPIPAFPDSVKPEKPLAASVRKAEDEQEEGQPVRMATFP
80 90 100 110 120 130
170 180 190 200 210 220
pF1KB8 SPAFPGSQTHSGPELGLVP---SPASLWPPPPSPAPS----STKPGPESSVSLLQGARPF
.:. ...:. : . : .: :: :. . : .. : :. .:: : :
NP_001 GPGSSPARAHQ-PAFLQPPEEDAPHSLRSDLPTSSDSKDFSTSIPKQEKLLSL-AGDSLF
140 150 160 170 180 190
230 240 250 260 270 280
pF1KB8 PFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSF
: .. ..: .:... ::..: :. :::. .. .. :.:.:.: .... :
NP_001 ---WSEADVVQATDDFNQNRKISQGTFADVYRGHRHGKPFVFKKLRETACSSPGSIERFF
200 210 220 230 240 250
290 300 310 320 330 340
pF1KB8 LTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRL
.:.. : :::.. :.:: :. ..: .. ::::.:::. : . :: ::::.
NP_001 QAELQICLRCCHPNVLPVLGFCAARQFHSFIYPYMANGSLQDRLQGQG-GSDPLPWPQRV
260 270 280 290 300 310
350 360 370 380 390 400
pF1KB8 DILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSS
.: : :...:: . .::...::::::::. :::::. .:.. .. :. .
NP_001 SICSGLLCAVEYLH--GLEIIHSNVKSSNVLLDQNLTPKLAH-PMAHLCPV--NKRSKYT
320 330 340 350 360
410 420 430 440 450 460
pF1KB8 MVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKD
:. .:. .: . :::::..:..:.:. .: :: :.:. :.:.: :. .. . . ::::
NP_001 MM-KTHLLRTSAAYLPEDFIRVGQLTKRVDIFSCGIVLAEVLTGIPAMDNNRSPV-YLKD
370 380 390 400 410 420
470 480 490 500 510
pF1KB8 LVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLGQL-----------ACCC
:. . . ..: : .. .. .: . : .. .: :.: :: :
NP_001 LLLSDIPSSTASLCSRKTGVENVMAKE-----ICQKYLEKGAGRLPEDCAEALATAACLC
430 440 450 460 470 480
520 530 540 550 560 570
pF1KB8 LHRRAKRRPPMTQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDE
:.:: . . : :.. ::. :. .:.:... :. . :. ....
NP_001 LRRRNTSLQEVCGSVAAVEERLRGRETLLPWSGLSEGTGSSSNTPEETDDVDNSSLDASS
490 500 510 520 530 540
580 590 600 610 620
pF1KB8 SLGGLSAALRSWHLTPSCPLDPAP--LREAGCPQGDTAGESSWGSGPGSRPTAVEGLALG
: .:.: . :: : . . :: ..:...:. : : : :
NP_001 S---MSVAPWAGAATPLLPTENGEGRLRVIVGREADSSSEACVGLEP---PQDV------
550 560 570 580
630 640 650 660 670 680
pF1KB8 SSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESD
. :: :: :..:..... ::.. .::..:.
NP_001 -----TETSWQIEINEAKRKLMENILLYKEEKVDSIELFGP
590 600 610 620
690
pF1KB8 EFQS
>>NP_001135995 (OMIM: 604459,611064) interleukin-1 recep (535 aa)
initn: 542 init1: 321 opt: 586 Z-score: 265.4 bits: 59.2 E(85289): 4.8e-08
Smith-Waterman score: 640; 33.7% identity (59.7% similar) in 419 aa overlap (231-643:97-488)
210 220 230 240 250 260
pF1KB8 APSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNT
: .::.:: ... :::: . :::. ..:
NP_001 ETANVTVDNVLIPEHNEKGILLKSSISFQNIIEGTRNFHKDFLIGEGEIFEVYRVEIQNL
70 80 90 100 110 120
270 280 290 300 310 320
pF1KB8 VYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNG
.:::: .:.. .. . ::.:.: : :.::::...:.: ... .::.: .. ::
NP_001 TYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNG
130 140 150 160 170 180
330 340 350 360 370
pF1KB8 SLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP-SLIHGDIKSSNVLLDERLT
.: :::.: .. : : : :. ::.: ..::..::. .: :.: :.:.:.:.:::...
NP_001 TLFDRLQCVGDTAP-LPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQ
190 200 210 220 230 240
380 390 400 410 420 430
pF1KB8 PKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVV
::: ::..:.: :: . :.. : :.:::::. :.:.. ::..:::.:
NP_001 PKLTDFAMAHFRSHL---EHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIV
250 260 270 280 290 300
440 450 460 470 480 490
pF1KB8 VLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQI
..:.:.: :.: . :.::..: :. : : : : :. . : .
NP_001 IMEVLTGCRVV-LDDPKHIQLRDLLRELMEKRG--LDSCLSFLDKKV-------PPCPRN
310 320 330 340 350
500 510 520 530 540 550
pF1KB8 YKKHLGQLACCCLHRRAKRRPPMTQE-NSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQ
.. .: :: : ::: :: : . :. :. . . . : : . : :.
NP_001 FSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLEN
360 370 380 390 400 410
560 570 580 590 600 610
pF1KB8 LQRGPNQPVESDES----LGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGS
. :. :::.::: : . .:: ..: . :.. : :... : .
NP_001 V---PSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFE--------CSQSEVM-FLSLDK
420 430 440 450 460
620 630 640 650 660 670
pF1KB8 GPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLP
: :. . :. . ::. : :. :.
NP_001 KPESKRNE-EACNMPSSSCEESWFPKYIVPSQDLRPYKVNIDPSSEAPGHSCRSRPVESS
470 480 490 500 510
>>NP_009130 (OMIM: 604459,611064) interleukin-1 receptor (596 aa)
initn: 611 init1: 321 opt: 586 Z-score: 264.8 bits: 59.2 E(85289): 5.2e-08
Smith-Waterman score: 654; 29.1% identity (53.5% similar) in 650 aa overlap (1-643:1-549)
10 20 30 40 50 60
pF1KB8 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGL
:::. : .: .:. .:...:: .. .. :.:. . : ::: ::
NP_009 MAGNCGA--RGALSAHTLLFDLPPALLGELCAVLDSCDGAL-----GWR---------GL
10 20 30 40
70 80 90 100 110
pF1KB8 LAPTPDAPRPAAA-LIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLL
: : ... : :: . .:: : .:: : ..: ..::...: ..
NP_009 ------AERLSSSWLDVRHIEKYVDQGKSGTRE--LLWSWAQKNKTIGDLLQVLQEMGHR
50 60 70 80 90
120 130 140 150 160 170
pF1KB8 RARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTH
:: .:: . ... .:.: ... .::. .
NP_009 RAIHLITNY----------------GAVLSPSE-------------KSYQEGGFPNILFK
100 110 120
180 190 200 210 220 230
pF1KB8 SGPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFS
: . : : : .. : ::... : .: .::.::
NP_009 ---ETANVTVDNVL-------IPEHNEKGI-----LLKSSISFQ------NIIEGTRNFH
130 140 150 160
240 250 260 270 280 290
pF1KB8 EELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVD
... :::: . :::. ..: .:::: .:.. .. . ::.:.: : :.::::..
NP_009 KDFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILE
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB8 FAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDS
.:.: ... .::.: .. ::.: :::.: . :: : :. ::.: ..::..::. .
NP_009 LAAYFTETEKFCLIYPYMRNGTLFDRLQC-VGDTAPLPWHIRIGILIGISKAIHYLHNVQ
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB8 P-SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLP
: :.: :.:.:.:.:::... ::: ::..:.: . :: . :.. : :.:
NP_009 PCSVICGSISSANILLDDQFQPKLTDFAMAHFR---SHLEHQSCTINMTSSSSKHLWYMP
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB8 EEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRST
::::. :.:.. ::..:::.:..:.:.: :.: . :.::..: :. : : :
NP_009 EEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVV-LDDPKHIQLRDLLRELMEKRG--LDSC
350 360 370 380 390
480 490 500 510 520 530
pF1KB8 QSTLQAGLAADAWAAPIAMQIYKKHLGQLACCCLHRRAKRRPPMTQE-NSYVSSTGRAHS
: :. .: . .. .: :: : ::: :: : . :. :. . .
NP_009 LSFLDK-------KVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASLYF
400 410 420 430 440 450
540 550 560 570 580 590
pF1KB8 GAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDES----LGGLSAALRSWHLTPSCPLDP
. : : . : :.. :. :::.::: : . .:: ..: . :..
NP_009 AEDPPTSLKSFRCPSPLFLENV---PSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFE-
460 470 480 490 500
600 610 620 630 640 650
pF1KB8 APLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQK
: :... : . : :. . :. . ::. : :. :.
NP_009 -------CSQSEVM-FLSLDKKPESKRNE-EACNMPSSSCEESWFPKYIVPSQDLRPYKV
510 520 530 540 550
660 670 680 690
pF1KB8 LALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
NP_009 NIDPSSEAPGHSCRSRPVESSCSSKFSWDEYEQYKKE
560 570 580 590
>>NP_057207 (OMIM: 606883,607676,610799) interleukin-1 r (460 aa)
initn: 551 init1: 253 opt: 475 Z-score: 221.2 bits: 50.8 E(85289): 1.4e-05
Smith-Waterman score: 609; 30.2% identity (56.3% similar) in 503 aa overlap (32-524:21-449)
10 20 30 40 50 60
pF1KB8 AGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGLL
:. : ..: . ::.. : ..
NP_057 MNKPITPSTYVRCLNVGLIRKLSDFIDPQE-----GWKKLA-----VAIK
10 20 30 40
70 80 90 100 110 120
pF1KB8 APTPDAPRPAAALIVRDQTELRLCERSGQR-TASVLWPWINRNARVADLVHILTHLQLLR
:. : : : : .. :. .:. :. .:. : . : :.::: .:
NP_057 KPSGD-DRYNQFHIRRFEALLQ----TGKSPTSELLFDWGTTNCTVGDLVDLL-------
50 60 70 80
130 140 150 160 170
pF1KB8 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLP--SSASTFLSPAFPGSQT
: . . :: : : .. ...:. :: . . ...: .. :...:. :.
NP_057 ---IQNEFFAPASLLLPDAVPKTANTLPSK-EAITVQQKQMPFCDKDRTLMTPVQNLEQS
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB8 HSGPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNF
. :: : .: :.. .. .: : . :.. :.::
NP_057 YM---------------PPDSSSP-------ENKSLEVSDTRFHSFSF--YELKNVTNNF
150 160 170 180
240 250 260 270 280 290
pF1KB8 SEEL------KIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRF
.:. :.:::::: ::.. . ::. :::.: .:. .::.: :.. ...
NP_057 DERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKC
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB8 RHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAI
.: :.:.. :. ... :::: ..::::: ::: : .. ::::: .: : :.: .:
NP_057 QHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSC-LDGTPPLSWHMRCKIAQGAANGI
250 260 270 280 290
360 370 380 390 400 410
pF1KB8 QFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFS-RFAGSSPSQSSMVARTQTVR
.:::.. :: ::::.:.:::: .: :..:::::: : .:: :. :..: .
NP_057 NFLHENHH--IHRDIKSANILLDEAFTAKISDFGLARASEKFA-----QTVMTSR---IV
300 310 320 330 340
420 430 440 450 460 470
pF1KB8 GTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEA
:: ::. : .. :... .: .:::::.:: ..: :: : . . : :. :: .:
NP_057 GTTAYMAPEALR-GEITPKSDIYSFGVVLLEIITGLPAVDEH-REPQLLLDIKEEIEDEE
350 360 370 380 390 400
480 490 500 510 520 530
pF1KB8 GVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLGQLACCCLHRRAKRRPPMTQENSYVSS
.. .. .. . :: .. . . . ..: :::.. ..:: . .
NP_057 ----KTIEDYIDKKMN-DADSTSV------EAMYSVASQCLHEKKNKRPDIKKVQQLLQE
410 420 430 440 450
540 550 560 570 580 590
pF1KB8 TGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPL
NP_057 MTAS
460
>>XP_005269002 (OMIM: 606883,607676,610799) PREDICTED: i (460 aa)
initn: 551 init1: 253 opt: 475 Z-score: 221.2 bits: 50.8 E(85289): 1.4e-05
Smith-Waterman score: 609; 30.2% identity (56.3% similar) in 503 aa overlap (32-524:21-449)
10 20 30 40 50 60
pF1KB8 AGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGLL
:. : ..: . ::.. : ..
XP_005 MNKPITPSTYVRCLNVGLIRKLSDFIDPQE-----GWKKLA-----VAIK
10 20 30 40
70 80 90 100 110 120
pF1KB8 APTPDAPRPAAALIVRDQTELRLCERSGQR-TASVLWPWINRNARVADLVHILTHLQLLR
:. : : : : .. :. .:. :. .:. : . : :.::: .:
XP_005 KPSGD-DRYNQFHIRRFEALLQ----TGKSPTSELLFDWGTTNCTVGDLVDLL-------
50 60 70 80
130 140 150 160 170
pF1KB8 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLP--SSASTFLSPAFPGSQT
: . . :: : : .. ...:. :: . . ...: .. :...:. :.
XP_005 ---IQNEFFAPASLLLPDAVPKTANTLPSK-EAITVQQKQMPFCDKDRTLMTPVQNLEQS
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB8 HSGPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNF
. :: : .: :.. .. .: : . :.. :.::
XP_005 YM---------------PPDSSSP-------ENKSLEVSDTRFHSFSF--YELKNVTNNF
150 160 170 180
240 250 260 270 280 290
pF1KB8 SEEL------KIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRF
.:. :.:::::: ::.. . ::. :::.: .:. .::.: :.. ...
XP_005 DERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKC
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB8 RHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAI
.: :.:.. :. ... :::: ..::::: ::: : .. ::::: .: : :.: .:
XP_005 QHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSC-LDGTPPLSWHMRCKIAQGAANGI
250 260 270 280 290
360 370 380 390 400 410
pF1KB8 QFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFS-RFAGSSPSQSSMVARTQTVR
.:::.. :: ::::.:.:::: .: :..:::::: : .:: :. :..: .
XP_005 NFLHENHH--IHRDIKSANILLDEAFTAKISDFGLARASEKFA-----QTVMTSR---IV
300 310 320 330 340
420 430 440 450 460 470
pF1KB8 GTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEA
:: ::. : .. :... .: .:::::.:: ..: :: : . . : :. :: .:
XP_005 GTTAYMAPEALR-GEITPKSDIYSFGVVLLEIITGLPAVDEH-REPQLLLDIKEEIEDEE
350 360 370 380 390 400
480 490 500 510 520 530
pF1KB8 GVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLGQLACCCLHRRAKRRPPMTQENSYVSS
.. .. .. . :: .. . . . ..: :::.. ..:: . .
XP_005 ----KTIEDYIDKKMN-DADSTSV------EAMYSVASQCLHEKKNKRPDIKKVQQLLQE
410 420 430 440 450
540 550 560 570 580 590
pF1KB8 TGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPL
XP_005 MTAS
460
693 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:00:11 2016 done: Fri Nov 4 12:00:12 2016
Total Scan time: 12.650 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]