Result of FASTA (ccds) for
pF1KB8352
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8352, 693 aa
1>>>pF1KB8352 693 - 693 aa - 693 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.4827+/-0.00107; mu= -12.1215+/- 0.063
mean_var=471.3751+/-103.550, 0's: 0 Z-trim(116.1): 107 B-trim: 279 in 1/51
Lambda= 0.059073
statistics sampled from 16595 (16698) to 16595 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.513), width: 16
Scan time: 3.290
The best scores are: opt bits E(32554)
CCDS35444.1 IRAK1 gene_id:3654|Hs108|chrX ( 682) 2933 264.7 3.2e-70
CCDS14740.1 IRAK1 gene_id:3654|Hs108|chrX ( 712) 2933 264.7 3.3e-70
CCDS35443.1 IRAK1 gene_id:3654|Hs108|chrX ( 633) 2665 241.8 2.3e-63
CCDS33697.1 IRAK2 gene_id:3656|Hs108|chr3 ( 625) 705 74.8 4.3e-13
>>CCDS35444.1 IRAK1 gene_id:3654|Hs108|chrX (682 aa)
initn: 3268 init1: 2929 opt: 2933 Z-score: 1374.2 bits: 264.7 E(32554): 3.2e-70
Smith-Waterman score: 4470; 94.2% identity (94.2% similar) in 708 aa overlap (1-693:1-682)
10 20 30 40 50 60
pF1KB8 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGL
:::::::::::::::::::::::::::::::::::::::::::::
CCDS35 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQF---------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 LAPTPDAPRPAAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 -----------AALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
50 60 70 80 90
130 140 150 160 170 180
pF1KB8 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB8 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB8 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQS
400 410 420 430 440 450
490 500 510 520
pF1KB8 TLQAGLAADAWAAPIAMQIYKKHL---------------GQLACCCLHRRAKRRPPMTQE
:::::::::::::::::::::::: :::::::::::::::::::::
CCDS35 TLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQE
460 470 480 490 500 510
530 540 550 560 570 580
pF1KB8 NSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 NSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHL
520 530 540 550 560 570
590 600 610 620 630 640
pF1KB8 TPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 TPSCPLDPAPLREAGCPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINP
580 590 600 610 620 630
650 660 670 680 690
pF1KB8 ARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 ARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
640 650 660 670 680
>>CCDS14740.1 IRAK1 gene_id:3654|Hs108|chrX (712 aa)
initn: 4411 init1: 2929 opt: 2933 Z-score: 1373.9 bits: 264.7 E(32554): 3.3e-70
Smith-Waterman score: 4309; 90.2% identity (90.2% similar) in 725 aa overlap (1-680:1-699)
10 20 30 40 50 60
pF1KB8 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGL
:::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQF---------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 LAPTPDAPRPAAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 -----------AALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
50 60 70 80 90
130 140 150 160 170 180
pF1KB8 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB8 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB8 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQS
400 410 420 430 440 450
490 500 510 520
pF1KB8 TLQAGLAADAWAAPIAMQIYKKHL---------------GQLACCCLHRRAKRRPPMTQ-
:::::::::::::::::::::::: ::::::::::::::::::::
CCDS14 TLQAGLAADAWAAPIAMQIYKKHLDPRPGPCPPELGLGLGQLACCCLHRRAKRRPPMTQV
460 470 480 490 500 510
530 540 550
pF1KB8 -----------------------------ENSYVSSTGRAHSGAAPWQPLAAPSGASAQA
:::::::::::::::::::::::::::::::
CCDS14 YERLEKLQAVVAGVPGHSEAASCIPPSPQENSYVSSTGRAHSGAAPWQPLAAPSGASAQA
520 530 540 550 560 570
560 570 580 590 600 610
pF1KB8 AEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 AEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGESSWGSG
580 590 600 610 620 630
620 630 640 650 660 670
pF1KB8 PGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 PGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPG
640 650 660 670 680 690
680 690
pF1KB8 LGLEQDRQGPEESDEFQS
:::::
CCDS14 LGLEQDRQGPEESDEFQS
700 710
>>CCDS35443.1 IRAK1 gene_id:3654|Hs108|chrX (633 aa)
initn: 4138 init1: 2656 opt: 2665 Z-score: 1251.2 bits: 241.8 E(32554): 2.3e-63
Smith-Waterman score: 4042; 88.7% identity (90.2% similar) in 693 aa overlap (1-693:1-633)
10 20 30 40 50 60
pF1KB8 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGL
:::::::::::::::::::::::::::::::::::::::::::::
CCDS35 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQF---------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 LAPTPDAPRPAAALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 -----------AALIVRDQTELRLCERSGQRTASVLWPWINRNARVADLVHILTHLQLLR
50 60 70 80 90
130 140 150 160 170 180
pF1KB8 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 ARDIITAWHPPAPLPSPGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFLSPAFPGSQTHS
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 GPELGLVPSPASLWPPPPSPAPSSTKPGPESSVSLLQGARPFPFCWPLCEISRGTHNFSE
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 ELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSFLTEVEQLSRFRHPNIVDF
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 AGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRLDILLGTARAIQFLHQDSP
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB8 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 SLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSSMVARTQTVRGTLAYLPEE
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB8 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKDLVEEEAEEAGVALRSTQS
:::::::::::::::::::::::::::::::::::::::: : :. :.. :.
CCDS35 YIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYL---VYER-------LEKLQA
400 410 420 430 440
490 500 510 520 530 540
pF1KB8 TLQAGLAADAWAAPIAMQIYKKHLGQLACCCLHRRAKRRPPMTQENSYVSSTGRAHSGAA
.. ::. . . :: :. :: :::::::::::::::::
CCDS35 VV-AGVPGHSEAAS----------------CI-------PPSPQENSYVSSTGRAHSGAA
450 460 470 480
550 560 570 580 590 600
pF1KB8 PWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 PWQPLAAPSGASAQAAEQLQRGPNQPVESDESLGGLSAALRSWHLTPSCPLDPAPLREAG
490 500 510 520 530 540
610 620 630 640 650 660
pF1KB8 CPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS35 CPQGDTAGESSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQKMVQKLALYEDG
550 560 570 580 590 600
670 680 690
pF1KB8 ALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
:::::::::::::::::::::::::::::::::
CCDS35 ALDSLQLLSSSSLPGLGLEQDRQGPEESDEFQS
610 620 630
>>CCDS33697.1 IRAK2 gene_id:3656|Hs108|chr3 (625 aa)
initn: 648 init1: 194 opt: 705 Z-score: 348.5 bits: 74.8 E(32554): 4.3e-13
Smith-Waterman score: 787; 28.4% identity (55.3% similar) in 682 aa overlap (18-668:4-623)
10 20 30 40 50 60
pF1KB8 MAGGPGPGEPAAPGAQHFLYEVPPWVMCRFYKVMDALEPADWCQFGGWRRAAGGREARGL
..:..: ::. . . :::: :: .:
CCDS33 MACYIYQLPSWVLDDLCRNMDALSEWDWMEF---------------
10 20 30
70 80 90 100 110
pF1KB8 LAPTPDAPRPAAALIVRDQTELRLCERSGQRTASV------LWPWINRNARVADLVHILT
:. .. : :.:: .: .:. .: :: : :.: : .:: .:
CCDS33 -----------ASYVITDLTQLRKI-KSMERVQGVSITRELLWWWGMRQATVQQLVDLLC
40 50 60 70
120 130 140 150 160
pF1KB8 HLQLLRARDIITAWHP-PA---PLPS-PGTTAPRPSSIPAPAEAEAWSPRKLPSSASTFL
.:.: :: .:: :.: : :.:. : .. :. . .:: . . : .::
CCDS33 RLELYRAAQIILNWKPAPEIRCPIPAFPDSVKPEKPLAASVRKAEDEQEEGQPVRMATFP
80 90 100 110 120 130
170 180 190 200 210 220
pF1KB8 SPAFPGSQTHSGPELGLVP---SPASLWPPPPSPAPS----STKPGPESSVSLLQGARPF
.:. ...:. : . : .: :: :. . : .. : :. .:: : :
CCDS33 GPGSSPARAHQ-PAFLQPPEEDAPHSLRSDLPTSSDSKDFSTSIPKQEKLLSL-AGDSLF
140 150 160 170 180 190
230 240 250 260 270 280
pF1KB8 PFCWPLCEISRGTHNFSEELKIGEGGFGCVYRAVMRNTVYAVKRLKENADLEWTAVKQSF
: .. ..: .:... ::..: :. :::. .. .. :.:.:.: .... :
CCDS33 ---WSEADVVQATDDFNQNRKISQGTFADVYRGHRHGKPFVFKKLRETACSSPGSIERFF
200 210 220 230 240 250
290 300 310 320 330 340
pF1KB8 LTEVEQLSRFRHPNIVDFAGYCAQNGFYCLVYGFLPNGSLEDRLHCQTQACPPLSWPQRL
.:.. : :::.. :.:: :. ..: .. ::::.:::. : . :: ::::.
CCDS33 QAELQICLRCCHPNVLPVLGFCAARQFHSFIYPYMANGSLQDRLQGQG-GSDPLPWPQRV
260 270 280 290 300 310
350 360 370 380 390 400
pF1KB8 DILLGTARAIQFLHQDSPSLIHGDIKSSNVLLDERLTPKLGDFGLARFSRFAGSSPSQSS
.: : :...:: . .::...::::::::. :::::. .:.. .. :. .
CCDS33 SICSGLLCAVEYLH--GLEIIHSNVKSSNVLLDQNLTPKLAH-PMAHLCPV--NKRSKYT
320 330 340 350 360
410 420 430 440 450 460
pF1KB8 MVARTQTVRGTLAYLPEEYIKTGRLAVDTDTFSFGVVVLETLAGQRAVKTHGARTKYLKD
:. .:. .: . :::::..:..:.:. .: :: :.:. :.:.: :. .. . . ::::
CCDS33 MM-KTHLLRTSAAYLPEDFIRVGQLTKRVDIFSCGIVLAEVLTGIPAMDNNRSPV-YLKD
370 380 390 400 410 420
470 480 490 500 510
pF1KB8 LVEEEAEEAGVALRSTQSTLQAGLAADAWAAPIAMQIYKKHLGQL-----------ACCC
:. . . ..: : .. .. .: . : .. .: :.: :: :
CCDS33 LLLSDIPSSTASLCSRKTGVENVMAKE-----ICQKYLEKGAGRLPEDCAEALATAACLC
430 440 450 460 470 480
520 530 540 550 560 570
pF1KB8 LHRRAKRRPPMTQENSYVSSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVESDE
:.:: . . : :.. ::. :. .:.:... :. . :. ....
CCDS33 LRRRNTSLQEVCGSVAAVEERLRGRETLLPWSGLSEGTGSSSNTPEETDDVDNSSLDASS
490 500 510 520 530 540
580 590 600 610 620
pF1KB8 SLGGLSAALRSWHLTPSCPLDPAP--LREAGCPQGDTAGESSWGSGPGSRPTAVEGLALG
: .:.: . :: : . . :: ..:...:. : : : :
CCDS33 S---MSVAPWAGAATPLLPTENGEGRLRVIVGREADSSSEACVGLEP---PQDV------
550 560 570 580
630 640 650 660 670 680
pF1KB8 SSASSSSEPPQIIINPARQKMVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESD
. :: :: :..:..... ::.. .::..:.
CCDS33 -----TETSWQIEINEAKRKLMENILLYKEEKVDSIELFGP
590 600 610 620
690
pF1KB8 EFQS
693 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:00:10 2016 done: Fri Nov 4 12:00:10 2016
Total Scan time: 3.290 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]