Result of FASTA (omim) for
pF1KB8344
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8344, 301 aa
1>>>pF1KB8344 301 - 301 aa - 301 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2927+/-0.000353; mu= 7.1066+/- 0.022
mean_var=146.9395+/-29.266, 0's: 0 Z-trim(118.1): 19 B-trim: 0 in 0/54
Lambda= 0.105805
statistics sampled from 30670 (30685) to 30670 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.36), width: 16
Scan time: 8.140
The best scores are: opt bits E(85289)
NP_005379 (OMIM: 604421) phosducin-like protein [H ( 301) 1980 313.6 3.1e-85
XP_016870274 (OMIM: 604421) PREDICTED: phosducin-l ( 236) 1201 194.6 1.6e-49
NP_072098 (OMIM: 171490) phosducin isoform b [Homo ( 194) 641 109.0 7.5e-24
XP_011507905 (OMIM: 171490) PREDICTED: phosducin i ( 246) 641 109.1 9e-24
NP_002588 (OMIM: 171490) phosducin isoform a [Homo ( 246) 641 109.1 9e-24
NP_689614 (OMIM: 611676) phosducin-like protein 2 ( 241) 271 52.6 8.9e-07
XP_011532676 (OMIM: 611676) PREDICTED: phosducin-l ( 209) 265 51.7 1.5e-06
NP_076970 (OMIM: 611678) phosducin-like protein 3 ( 239) 257 50.5 3.9e-06
XP_016860379 (OMIM: 611678) PREDICTED: phosducin-l ( 189) 232 46.6 4.6e-05
>>NP_005379 (OMIM: 604421) phosducin-like protein [Homo (301 aa)
initn: 1980 init1: 1980 opt: 1980 Z-score: 1651.2 bits: 313.6 E(85289): 3.1e-85
Smith-Waterman score: 1980; 99.7% identity (100.0% similar) in 301 aa overlap (1-301:1-301)
10 20 30 40 50 60
pF1KB8 MTTLDDKLLGEKLQYYYSSSEDEDSDHEDKDRGRCAPASSSVPAEAELAGEGISVNTGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MTTLDDKLLGEKLQYYYSSSEDEDSDHEDKDRGRCAPASSSVPAEAELAGEGISVNTGPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GVINDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GVINDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVESSVIGASSQFTRNALPALLIYK
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
NP_005 IVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVKSSVIGASSQFTRNALPALLIYK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 GGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEI
250 260 270 280 290 300
pF1KB8 D
:
NP_005 D
>>XP_016870274 (OMIM: 604421) PREDICTED: phosducin-like (236 aa)
initn: 1199 init1: 1199 opt: 1201 Z-score: 1010.0 bits: 194.6 E(85289): 1.6e-49
Smith-Waterman score: 1201; 82.9% identity (88.6% similar) in 228 aa overlap (81-301:9-236)
60 70 80 90 100
pF1KB8 EGISVNTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQ----
: .. ..: :.. . . :
XP_016 MISCWGRNCSTTIAAVRMRTVTTRTRTEADVPQPAVLC
10 20 30
110 120 130 140 150 160
pF1KB8 -KQKDLQEKISG--KMTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFE
.. . : : : .:::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQRLSWQAKASQLTQMTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFE
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 ISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVESSVIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::
XP_016 ISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVKSSVIG
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB8 ASSQFTRNALPALLIYKGGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLLPEKEVLVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASSQFTRNALPALLIYKGGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLLPEKEVLVLT
160 170 180 190 200 210
290 300
pF1KB8 SVRNSATCHSEDSDLEID
::::::::::::::::::
XP_016 SVRNSATCHSEDSDLEID
220 230
>>NP_072098 (OMIM: 171490) phosducin isoform b [Homo sap (194 aa)
initn: 660 init1: 640 opt: 641 Z-score: 549.2 bits: 109.0 E(85289): 7.5e-24
Smith-Waterman score: 641; 48.6% identity (84.2% similar) in 183 aa overlap (104-286:5-187)
80 90 100 110 120 130
pF1KB8 TEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNEDQDD
.... :: .:..: ::...:. .......:
NP_072 MSSPQSRNGKDSKERVSRKMSIQEYELIHKEKED
10 20 30
140 150 160 170 180 190
pF1KB8 EEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIP
:. :..::.: :..:.:.: ::.. :.:. .:. ::. :.:: : .:.::::::::
NP_072 ENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYEDGIK
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB8 GTEAMNGCMICLAAEYPAVKFCKVESSVIGASSQFTRNALPALLIYKGGELIGNFVRVTD
: .:.:. . ::::::: :::::...: ::...:. ..::.::::::::::.::. :..
NP_072 GCDALNSSLTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFISVAE
100 110 120 130 140 150
260 270 280 290 300
pF1KB8 QLGDDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID
:....::: :.:.::.:.:::::.:: :: ..
NP_072 QFAEEFFAGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE
160 170 180 190
>>XP_011507905 (OMIM: 171490) PREDICTED: phosducin isofo (246 aa)
initn: 753 init1: 640 opt: 641 Z-score: 547.8 bits: 109.1 E(85289): 9e-24
Smith-Waterman score: 733; 45.3% identity (79.2% similar) in 236 aa overlap (51-286:14-239)
30 40 50 60 70 80
pF1KB8 EDEDSDHEDKDRGRCAPASSSVPAEAELAGEGISVNTGPKGVINDWRRFKQLETEQREEQ
:: ...:::::::::::.:: ::... .
XP_011 MEEAKSQSLEEDFEGQATHTGPKGVINDWRKFK-LESQDSDSI
10 20 30 40
90 100 110 120 130 140
pF1KB8 CREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNEDQDDEEFLQQY
.......: .... :: .:..: ::...:. .......::. :..:
XP_011 PPSKKEILRQMS---------SPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKY
50 60 70 80 90
150 160 170 180 190 200
pF1KB8 RKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNG
:.: :..:.:.: ::.. :.:. .:. ::. :.:: : .:.:::::::: : .:.:.
XP_011 RRQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNS
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB8 CMICLAAEYPAVKFCKVESSVIGASSQFTRNALPALLIYKGGELIGNFVRVTDQLGDDFF
. ::::::: :::::...: ::...:. ..::.::::::::::.::. :..:....::
XP_011 SLTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFF
160 170 180 190 200 210
270 280 290 300
pF1KB8 AVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID
: :.:.::.:.:::::.:: :: ..
XP_011 AGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE
220 230 240
>>NP_002588 (OMIM: 171490) phosducin isoform a [Homo sap (246 aa)
initn: 753 init1: 640 opt: 641 Z-score: 547.8 bits: 109.1 E(85289): 9e-24
Smith-Waterman score: 733; 45.3% identity (79.2% similar) in 236 aa overlap (51-286:14-239)
30 40 50 60 70 80
pF1KB8 EDEDSDHEDKDRGRCAPASSSVPAEAELAGEGISVNTGPKGVINDWRRFKQLETEQREEQ
:: ...:::::::::::.:: ::... .
NP_002 MEEAKSQSLEEDFEGQATHTGPKGVINDWRKFK-LESQDSDSI
10 20 30 40
90 100 110 120 130 140
pF1KB8 CREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNEDQDDEEFLQQY
.......: .... :: .:..: ::...:. .......::. :..:
NP_002 PPSKKEILRQMS---------SPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKY
50 60 70 80 90
150 160 170 180 190 200
pF1KB8 RKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNG
:.: :..:.:.: ::.. :.:. .:. ::. :.:: : .:.:::::::: : .:.:.
NP_002 RRQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNS
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB8 CMICLAAEYPAVKFCKVESSVIGASSQFTRNALPALLIYKGGELIGNFVRVTDQLGDDFF
. ::::::: :::::...: ::...:. ..::.::::::::::.::. :..:....::
NP_002 SLTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFF
160 170 180 190 200 210
270 280 290 300
pF1KB8 AVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID
: :.:.::.:.:::::.:: :: ..
NP_002 AGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE
220 230 240
>>NP_689614 (OMIM: 611676) phosducin-like protein 2 [Hom (241 aa)
initn: 203 init1: 122 opt: 271 Z-score: 242.7 bits: 52.6 E(85289): 8.9e-07
Smith-Waterman score: 271; 29.6% identity (62.9% similar) in 213 aa overlap (100-297:28-232)
70 80 90 100 110 120
pF1KB8 KQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQ--QKQKDLQEKISGKMTLKEFAIM
:: ::. . ::. . : :::: ..
NP_689 MQDPNEDTEWNDILRDFGILPPKEESKDEIEEMVLRLQKEAMVKPFEKMTLAQLK-E
10 20 30 40 50
130 140 150 160 170 180
pF1KB8 NEDQDDEEFLQQ---YRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSIVIM
::. ::: .: :::.:..: . :.: .: .. ::: :. ... . . .... ..
NP_689 AEDEFDEEDMQAVETYRKKRLQEWKA-LKKKQKFGELREIS-GNQYVNEVTNAEEDVWVI
60 70 80 90 100 110
190 200 210 220 230 240
pF1KB8 VHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVESSVIGASSQ-FTRNALPALLIYKGGE
.:.:...:: .: . :: ..: .:: : ..... : . : ::....::.:.
NP_689 IHLYRSSIPMCLLVNQHLSLLARKFPETKFVK---AIVNSCIQHYHDNCLPTIFVYKNGQ
120 130 140 150 160 170
250 260 270 280 290
pF1KB8 LIGNFVRVTDQLGDDFFAVDLEAFLQEFGLL-------PEKEV--LVLTSVRNSATCHSE
. ..:. . . : .. .:: : : : . :.:.. ....:.::.. : .
NP_689 IEAKFIGIIECGGINLKLEELEWKLAEVGAIQTDLEENPRKDMVDMMVSSIRNTSI-H-D
180 190 200 210 220
300
pF1KB8 DSDLEID
:::
NP_689 DSDSSNSDNDTK
230 240
>>XP_011532676 (OMIM: 611676) PREDICTED: phosducin-like (209 aa)
initn: 219 init1: 119 opt: 265 Z-score: 238.6 bits: 51.7 E(85289): 1.5e-06
Smith-Waterman score: 265; 29.1% identity (63.1% similar) in 203 aa overlap (108-297:6-200)
80 90 100 110 120 130
pF1KB8 EEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNEDQDDEEFL
::. . : :::: .. ::. ::: .
XP_011 MVLRLQKEAMVKPFEKMTLAQLK-EAEDEFDEEDM
10 20 30
140 150 160 170 180 190
pF1KB8 QQ---YRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIPG
: :::.:..: . :.: .: .. ::: :. ... . . .... ...:.:...::
XP_011 QAVETYRKKRLQEWKA-LKKKQKFGELREIS-GNQYVNEVTNAEEDVWVIIHLYRSSIPM
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB8 TEAMNGCMICLAAEYPAVKFCKVESSVIGASSQ-FTRNALPALLIYKGGELIGNFVRVTD
.: . :: ..: .:: : ..... : . : ::....::.:.. ..:. . .
XP_011 CLLVNQHLSLLARKFPETKFVK---AIVNSCIQHYHDNCLPTIFVYKNGQIEAKFIGIIE
100 110 120 130 140
260 270 280 290 300
pF1KB8 QLGDDFFAVDLEAFLQEFGLL-------PEKEV--LVLTSVRNSATCHSEDSDLEID
: .. .:: : : : . :.:.. ....:.::. . : .:::
XP_011 CGGINLKLEELEWKLAEVGAIQTDLEENPRKDMVDMMVSSIRNT-SIH-DDSDSSNSDND
150 160 170 180 190 200
XP_011 TK
>>NP_076970 (OMIM: 611678) phosducin-like protein 3 [Hom (239 aa)
initn: 247 init1: 117 opt: 257 Z-score: 231.2 bits: 50.5 E(85289): 3.9e-06
Smith-Waterman score: 257; 29.3% identity (61.9% similar) in 215 aa overlap (101-301:30-239)
80 90 100 110 120
pF1KB8 QLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGK---MTLKEFAIM
::: ...:. ::... :::.:.
NP_076 MQDPNADTEWNDILRKKGILPPKESLKELEEEAEEEQRILQQSVVKTYEDMTLEELEDH
10 20 30 40 50
130 140 150 160 170 180
pF1KB8 NED--QDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSIVIMV
... ..::. ...::..:. : . :. .: .:.::: :. ... . : ... ...
NP_076 EDEFNEEDERAIEMYRRRRLAEWKATKLKN-KFGEVLEIS-GKDYVQEVTKAGEGLWVIL
60 70 80 90 100 110
190 200 210 220 230 240
pF1KB8 HIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVESSVIGASSQFTRNALPALLIYKGGELI
:.:..::: .: . :: ..: ::: :. :.. . :: ::....: :..
NP_076 HLYKQGIPLCALINQHLSGLARKFPDVKFIKAISTTC-IPNYPDRN-LPTIFVYLEGDIK
120 130 140 150 160 170
250 260 270 280 290
pF1KB8 GNFVRVTDQLGDDFFAVDLEAFLQEFGLL-------PEKEV--LVLTSVRNSATCHSEDS
..:. : .. .:: :.: : . :.: . ..:.::: :. ..::
NP_076 AQFIGPLVFGGMNLTRDELEWKLSESGAIMTDLEENPKKPIEDVLLSSVRRSVL-MKRDS
180 190 200 210 220 230
300
pF1KB8 DLEID
: : :
NP_076 DSEGD
>>XP_016860379 (OMIM: 611678) PREDICTED: phosducin-like (189 aa)
initn: 188 init1: 113 opt: 232 Z-score: 212.0 bits: 46.6 E(85289): 4.6e-05
Smith-Waterman score: 232; 29.4% identity (61.9% similar) in 194 aa overlap (119-301:1-189)
90 100 110 120 130 140
pF1KB8 KKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNED--QDDEEFLQQYRKQRME
:::.:. ... ..::. ...::..:.
XP_016 MTLEELEDHEDEFNEEDERAIEMYRRRRLA
10 20 30
150 160 170 180 190 200
pF1KB8 EMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLA
: . :. .: .:.::: :. ... . : ... ...:.:..::: .: . ::
XP_016 EWKATKLKN-KFGEVLEIS-GKDYVQEVTKAGEGLWVILHLYKQGIPLCALINQHLSGLA
40 50 60 70 80
210 220 230 240 250 260
pF1KB8 AEYPAVKFCKVESSVIGASSQFTRNALPALLIYKGGELIGNFVRVTDQLGDDFFAVDLEA
..: ::: :. :.. . :: ::....: :.. ..:. : .. .::
XP_016 RKFPDVKFIKAISTTC-IPNYPDRN-LPTIFVYLEGDIKAQFIGPLVFGGMNLTRDELEW
90 100 110 120 130 140
270 280 290 300
pF1KB8 FLQEFGLL-------PEKEV--LVLTSVRNSATCHSEDSDLEID
:.: : . :.: . ..:.::: :. ..::: : :
XP_016 KLSESGAIMTDLEENPKKPIEDVLLSSVRRSVL-MKRDSDSEGD
150 160 170 180
301 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:56:52 2016 done: Fri Nov 4 11:56:53 2016
Total Scan time: 8.140 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]