Result of FASTA (omim) for
pF1KB8326
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8326, 366 aa
1>>>pF1KB8326 366 - 366 aa - 366 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.0290+/-0.00044; mu= -16.9410+/- 0.027
mean_var=552.0474+/-117.965, 0's: 0 Z-trim(125.2): 87 B-trim: 2518 in 2/58
Lambda= 0.054587
statistics sampled from 48194 (48309) to 48194 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.827), E-opt: 0.2 (0.566), width: 16
Scan time: 7.910
The best scores are: opt bits E(85289)
NP_057512 (OMIM: 606363) ABI gene family member 3 ( 366) 2497 210.6 4.6e-54
XP_016880210 (OMIM: 606363) PREDICTED: ABI gene fa ( 365) 2472 208.6 1.8e-53
XP_005257486 (OMIM: 606363) PREDICTED: ABI gene fa ( 373) 2465 208.1 2.7e-53
XP_011523175 (OMIM: 606363) PREDICTED: ABI gene fa ( 372) 2448 206.8 6.7e-53
NP_001128658 (OMIM: 606363) ABI gene family member ( 360) 2440 206.1 1e-52
NP_001171595 (OMIM: 603050) abl interactor 1 isofo ( 388) 753 73.3 1.1e-12
XP_005252389 (OMIM: 603050) PREDICTED: abl interac ( 503) 720 70.8 7.7e-12
XP_016858634 (OMIM: 606442) PREDICTED: abl interac ( 396) 692 68.5 3e-11
XP_006717424 (OMIM: 603050) PREDICTED: abl interac ( 447) 686 68.1 4.5e-11
NP_001012770 (OMIM: 603050) abl interactor 1 isofo ( 476) 686 68.1 4.7e-11
NP_001171592 (OMIM: 603050) abl interactor 1 isofo ( 446) 684 67.9 5e-11
XP_005252390 (OMIM: 603050) PREDICTED: abl interac ( 475) 684 67.9 5.2e-11
XP_016858635 (OMIM: 606442) PREDICTED: abl interac ( 396) 671 66.8 9.4e-11
XP_006712249 (OMIM: 606442) PREDICTED: abl interac ( 397) 671 66.8 9.4e-11
NP_001171594 (OMIM: 603050) abl interactor 1 isofo ( 393) 661 66.0 1.6e-10
NP_001269855 (OMIM: 606442) abl interactor 2 isofo ( 507) 661 66.2 1.9e-10
XP_005246275 (OMIM: 606442) PREDICTED: abl interac ( 536) 661 66.2 2e-10
XP_016858630 (OMIM: 606442) PREDICTED: abl interac ( 426) 654 65.5 2.5e-10
XP_016858631 (OMIM: 606442) PREDICTED: abl interac ( 425) 653 65.4 2.6e-10
XP_016858615 (OMIM: 606442) PREDICTED: abl interac ( 473) 648 65.1 3.7e-10
XP_016858613 (OMIM: 606442) PREDICTED: abl interac ( 474) 647 65.0 3.9e-10
NP_005750 (OMIM: 606442) abl interactor 2 isoform ( 475) 647 65.0 4e-10
XP_016858633 (OMIM: 606442) PREDICTED: abl interac ( 403) 643 64.6 4.4e-10
XP_016858627 (OMIM: 606442) PREDICTED: abl interac ( 431) 640 64.4 5.4e-10
XP_016858623 (OMIM: 606442) PREDICTED: abl interac ( 445) 639 64.4 5.8e-10
XP_005246283 (OMIM: 606442) PREDICTED: abl interac ( 446) 639 64.4 5.9e-10
XP_016858616 (OMIM: 606442) PREDICTED: abl interac ( 473) 637 64.2 6.8e-10
XP_016858614 (OMIM: 606442) PREDICTED: abl interac ( 474) 637 64.2 6.8e-10
XP_011517591 (OMIM: 603050) PREDICTED: abl interac ( 302) 628 63.3 8.1e-10
XP_016858625 (OMIM: 606442) PREDICTED: abl interac ( 444) 631 63.7 9e-10
XP_016858624 (OMIM: 606442) PREDICTED: abl interac ( 445) 631 63.7 9e-10
XP_016870947 (OMIM: 603050) PREDICTED: abl interac ( 478) 628 63.5 1.1e-09
XP_006717423 (OMIM: 603050) PREDICTED: abl interac ( 479) 628 63.5 1.1e-09
XP_005246282 (OMIM: 606442) PREDICTED: abl interac ( 458) 627 63.4 1.1e-09
XP_006717422 (OMIM: 603050) PREDICTED: abl interac ( 507) 628 63.6 1.2e-09
NP_005461 (OMIM: 603050) abl interactor 1 isoform ( 508) 628 63.6 1.2e-09
XP_005246278 (OMIM: 606442) PREDICTED: abl interac ( 487) 627 63.5 1.2e-09
XP_016858620 (OMIM: 606442) PREDICTED: abl interac ( 457) 626 63.4 1.2e-09
XP_016858612 (OMIM: 606442) PREDICTED: abl interac ( 486) 626 63.4 1.3e-09
NP_001171593 (OMIM: 603050) abl interactor 1 isofo ( 422) 617 62.6 1.9e-09
XP_016858618 (OMIM: 606442) PREDICTED: abl interac ( 464) 618 62.7 1.9e-09
XP_016858611 (OMIM: 606442) PREDICTED: abl interac ( 491) 618 62.8 2e-09
XP_006712242 (OMIM: 606442) PREDICTED: abl interac ( 493) 618 62.8 2e-09
XP_016858619 (OMIM: 606442) PREDICTED: abl interac ( 463) 616 62.6 2.1e-09
XP_011508774 (OMIM: 606442) PREDICTED: abl interac ( 492) 616 62.6 2.2e-09
XP_016870948 (OMIM: 603050) PREDICTED: abl interac ( 290) 596 60.8 4.5e-09
NP_001171591 (OMIM: 603050) abl interactor 1 isofo ( 451) 596 61.0 6.2e-09
NP_001012769 (OMIM: 603050) abl interactor 1 isofo ( 452) 596 61.0 6.2e-09
NP_001171590 (OMIM: 603050) abl interactor 1 isofo ( 480) 596 61.0 6.4e-09
NP_001012768 (OMIM: 603050) abl interactor 1 isofo ( 481) 596 61.0 6.5e-09
>>NP_057512 (OMIM: 606363) ABI gene family member 3 isof (366 aa)
initn: 2497 init1: 2497 opt: 2497 Z-score: 1091.7 bits: 210.6 E(85289): 4.6e-54
Smith-Waterman score: 2497; 99.7% identity (100.0% similar) in 366 aa overlap (1-366:1-366)
10 20 30 40 50 60
pF1KB8 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKQKALEETMAFTTQALAS
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_057 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 LDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGN
310 320 330 340 350 360
pF1KB8 YVEPSC
::::::
NP_057 YVEPSC
>>XP_016880210 (OMIM: 606363) PREDICTED: ABI gene family (365 aa)
initn: 1477 init1: 1477 opt: 2472 Z-score: 1081.0 bits: 208.6 E(85289): 1.8e-53
Smith-Waterman score: 2472; 99.2% identity (99.5% similar) in 366 aa overlap (1-366:1-365)
10 20 30 40 50 60
pF1KB8 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKQKALEETMAFTTQALAS
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
XP_016 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS
:::::::::::::::::::::::::::: :::::: ::::::::::::::::::::::::
XP_016 TLGRPPRIPEPVHLPVVPDGRLSAASSAFSLASAG-AEGVGGAPTPKGQAAPPAPPLPSS
190 200 210 220 230
250 260 270 280 290 300
pF1KB8 LDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPD
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB8 EPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGN
300 310 320 330 340 350
pF1KB8 YVEPSC
::::::
XP_016 YVEPSC
360
>>XP_005257486 (OMIM: 606363) PREDICTED: ABI gene family (373 aa)
initn: 1803 init1: 1760 opt: 2465 Z-score: 1077.9 bits: 208.1 E(85289): 2.7e-53
Smith-Waterman score: 2465; 97.6% identity (97.9% similar) in 373 aa overlap (1-366:1-373)
10 20 30 40 50 60
pF1KB8 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKQKALEETMAFTTQALAS
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
XP_005 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_005 TLGRPPRIPEPVHLPVVPDGRLSAASSAFSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS
190 200 210 220 230 240
250 260 270 280 290
pF1KB8 LDPPPPPAAVEVFQRPPTLEELSPPPP-------DEELPLPLDLPPPPPLDGDELGLPPP
::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_005 LDPPPPPAAVEVFQRPPTLEELSPPPPAFLLFPQDEELPLPLDLPPPPPLDGDELGLPPP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 PPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEG
310 320 330 340 350 360
360
pF1KB8 TGFFPGNYVEPSC
:::::::::::::
XP_005 TGFFPGNYVEPSC
370
>>XP_011523175 (OMIM: 606363) PREDICTED: ABI gene family (372 aa)
initn: 1822 init1: 1460 opt: 2448 Z-score: 1070.7 bits: 206.8 E(85289): 6.7e-53
Smith-Waterman score: 2448; 97.3% identity (97.6% similar) in 373 aa overlap (1-366:1-372)
10 20 30 40 50 60
pF1KB8 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKQKALEETMAFTTQALAS
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
XP_011 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS
:::::::::::::::::::::::::::: :::::: ::::::::::::::::::::::::
XP_011 TLGRPPRIPEPVHLPVVPDGRLSAASSAFSLASAG-AEGVGGAPTPKGQAAPPAPPLPSS
190 200 210 220 230
250 260 270 280 290
pF1KB8 LDPPPPPAAVEVFQRPPTLEELSPPPP-------DEELPLPLDLPPPPPLDGDELGLPPP
::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_011 LDPPPPPAAVEVFQRPPTLEELSPPPPAFLLFPQDEELPLPLDLPPPPPLDGDELGLPPP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 PPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEG
300 310 320 330 340 350
360
pF1KB8 TGFFPGNYVEPSC
:::::::::::::
XP_011 TGFFPGNYVEPSC
360 370
>>NP_001128658 (OMIM: 606363) ABI gene family member 3 i (360 aa)
initn: 1907 init1: 1907 opt: 2440 Z-score: 1067.5 bits: 206.1 E(85289): 1e-52
Smith-Waterman score: 2440; 98.1% identity (98.4% similar) in 366 aa overlap (1-366:1-360)
10 20 30 40 50 60
pF1KB8 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKQKALEETMAFTTQALAS
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_001 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
::::::::::::::::::::::::::::: :::::::::::::::::::::::::
NP_001 VAYQVGNLAGHTLRMLDLQGAALRQVEAR------MVNMHMEKVARREIGTLATVQRLPP
70 80 90 100 110
130 140 150 160 170 180
pF1KB8 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB8 LDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPPPPPGFGPD
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB8 EPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGN
300 310 320 330 340 350
pF1KB8 YVEPSC
::::::
NP_001 YVEPSC
360
>>NP_001171595 (OMIM: 603050) abl interactor 1 isoform k (388 aa)
initn: 884 init1: 606 opt: 753 Z-score: 349.1 bits: 73.3 E(85289): 1.1e-12
Smith-Waterman score: 1009; 42.9% identity (68.6% similar) in 385 aa overlap (1-363:1-381)
10 20 30 40 50 60
pF1KB8 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKQKALEETMAFTTQALAS
:::::.: : :::.:..:: ... : :::::::.::.:::::.:::::: :.:::.:::
NP_001 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
::::.. ::...:..::.:.. ::..:. .. ..: :..: ::::::::: :.: .
NP_001 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRK---SIKAPATP
.:.::: :. . : :.:... :::.:::.: ..: .::::::: . : :. :
NP_001 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKHGNNQPARTGTLSRTNPPTQKPPSPP
130 140 150 160 170 180
180 190 200 210 220
pF1KB8 ASA--TLGR--PPRIPEPVHLPVVPDGRLSAASSASSLASAG----------SAEGVGGA
:. :::: : . :::. :.::. ... . .: : : . : .:.
NP_001 MSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB8 PTPKGQAAPPAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPP-
. ... . .: .. : ::. : . : :::: ...:. : :::::
NP_001 SGSRENSGSSSIGIPIAVPTPSPPTIGPVADSPTP----PPPPPPDDIPMFDDSPPPPPP
250 260 270 280 290
290 300 310 320 330
pF1KB8 ----LDGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVT
. .: .. .. .:.:.: .:.::::..: ::..::.:::: ::..: :
NP_001 PPVDYEDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVI
300 310 320 330 340 350
340 350 360
pF1KB8 RRYSDGWCEGVSSEGTGFFPGNYVEPSC
.. .::: ::: .. ::.:::::::
NP_001 KKNDDGWYEGVCNRVTGLFPGNYVESIMHYTD
360 370 380
>>XP_005252389 (OMIM: 603050) PREDICTED: abl interactor (503 aa)
initn: 882 init1: 606 opt: 720 Z-score: 333.6 bits: 70.8 E(85289): 7.7e-12
Smith-Waterman score: 729; 43.1% identity (68.6% similar) in 306 aa overlap (1-296:1-303)
10 20 30 40 50 60
pF1KB8 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKQKALEETMAFTTQALAS
:::::.: : :::.:..:: ... : :::::::.::.:::::.:::::: :.:::.:::
XP_005 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
::::.. ::...:..::.:.. ::..:. .. ..: :..: ::::::::: :.: .
XP_005 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRK---SIKAPATP
.:.::: :. . : :.:... :::.:::.: ..: .::::::: . : :. :
XP_005 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKHGNNQPARTGTLSRTNPPTQKPPSPP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 ASA--TLGR--PPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAP-TPKGQAAP
:. :::: : . :::. :.::. ... . .: : : . ... : : .:...
XP_005 MSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 PAPPLPSSLDPPPPPAAVEVFQRPPTL--EELSPPPPDEELPLPLDLPPPPPLDGDELGL
. :. . : :: . :::. :..: :::. : : : : :.. ..
XP_005 SGSRENSGSSSIGIPIAVPT-PSPPTIGPENISVPPPSGAPPAP-PLAPLLPVS-TVIAA
250 260 270 280 290
300 310 320 330 340 350
pF1KB8 PPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVS
: ::
XP_005 PGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVTAQFSAQPHVNGGPLYSQNSISI
300 310 320 330 340 350
>--
initn: 290 init1: 290 opt: 388 Z-score: 192.3 bits: 44.7 E(85289): 0.00057
Smith-Waterman score: 388; 33.8% identity (59.5% similar) in 210 aa overlap (161-363:304-496)
140 150 160 170 180 190
pF1KB8 PPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPE
:. ::..:. . .: .:.. : : :
XP_005 PPPSGAPPAPPLAPLLPVSTVIAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPS
280 290 300 310 320 330
200 210 220 230 240
pF1KB8 PVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAA-
..: ::. ...: . .. . ::: ::.:. : : : ..
XP_005 -----------VTAQFSAQPHVNGGPLYSQNSI-----SIAPPPPPMPQ-LTPQIPLTGF
340 350 360 370
250 260 270 280 290 300
pF1KB8 -VEVFQRPPTLEELSPPPPDEELPLPLDLPPPPP-----LDGDELGLPPPPPGFGPDEPS
..: . :::: ...:. : ::::: . .: .. .. .:.
XP_005 VARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPA
380 390 400 410 420 430
310 320 330 340 350 360
pF1KB8 WVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE
:.: .:.::::..: ::..::.:::: ::..: : .. .::: ::: .. ::.:::::::
XP_005 WAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE
440 450 460 470 480 490
pF1KB8 PSC
XP_005 SIMHYTD
500
>>XP_016858634 (OMIM: 606442) PREDICTED: abl interactor (396 aa)
initn: 823 init1: 547 opt: 692 Z-score: 323.0 bits: 68.5 E(85289): 3e-11
Smith-Waterman score: 923; 42.1% identity (65.2% similar) in 397 aa overlap (1-363:1-389)
10 20 30 40 50 60
pF1KB8 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKQKALEETMAFTTQALAS
:::::.: : ::: ::.:: ... : :::::::.::.:..:::.::::: :.:::.:::
XP_016 MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
::: ...::...:.:::.:.. ::..:. .. ..: :..: ::::::::: :.: .
XP_016 VAYLINTLANNVLQMLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASA
.:.::: :: . : :.:... :::::::.: .::: . : : : .:: .
XP_016 THKIIAPANLERPVRYIRKPIDYTILDDIGHGVK-VSTQNMKMGGLPR------TTPPTQ
130 140 150 160 170
190 200 210 220 230
pF1KB8 TLGRPPRIPEPVHLPVVPDGRLSAASSASSLASAGSAE-GVGGA-PTPKGQAAPPAPPL-
:: . . : .: .: .:: ..::. :: : :::. .. :. :.
XP_016 KPPSPPMSGKGT-LGSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHPVQ
180 190 200 210 220 230
240 250 260 270 280
pF1KB8 ------PSSLDPPPPPAAVEVFQRPPTL-------EELSPPPPDEELPLPLDLPPPPPLD
:.: :: .. ..:::.. .... : . :. :::::..
XP_016 FYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSDTPPPPPPVE
240 250 260 270 280 290
290 300 310 320
pF1KB8 G---DELGLPPPPP---------------GFGPDEPSWVPASYLEKVVTLYPYTSQKDNE
:: ::::: .. ..: :.: :::::::..: ::..:..:
XP_016 EPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKVVAIYDYTKDKEDE
300 310 320 330 340 350
330 340 350 360
pF1KB8 LSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC
:::.::..: : .. .::: ::: . ::.:::::::
XP_016 LSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVESIMHYSE
360 370 380 390
>>XP_006717424 (OMIM: 603050) PREDICTED: abl interactor (447 aa)
initn: 920 init1: 606 opt: 686 Z-score: 319.8 bits: 68.1 E(85289): 4.5e-11
Smith-Waterman score: 753; 38.3% identity (60.2% similar) in 397 aa overlap (1-320:1-397)
10 20 30 40 50 60
pF1KB8 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKQKALEETMAFTTQALAS
:::::.: : :::.:..:: ... : :::::::.::.:::::.:::::: :.:::.:::
XP_006 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
::::.. ::...:..::.:.. ::..:. .. ..: :..: ::::::::: :.: .
XP_006 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRK---SIKAPATP
.:.::: :. . : :.:... :::.:::.: ..: .::::::: . : :. :
XP_006 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKHGNNQPARTGTLSRTNPPTQKPPSPP
130 140 150 160 170 180
180 190 200 210
pF1KB8 ASA--TLGR--PPRIPEPVHLPVVPD------GRLSAASSASSLAS--------AGSAEG
:. :::: : . :::. :.::. .::.. : . :: .::. :
XP_006 MSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGG
190 200 210 220 230 240
220 230 240
pF1KB8 VGG--------------APTPK----GQAAPPAPP----------------LPSSLDPP-
:. .:::. : ::: . : :: .
XP_006 SGSRENSGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGG
250 260 270 280 290 300
250 260 270 280
pF1KB8 ---PPPAAVEVFQRP-----PTLEELS--------PPPPDEELPLPLDLPPPPP-----L
: .... .: : . : :::: ...:. : :::::
XP_006 YRRTPSVTAQFSAQPHVNGGPLYSQNSIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDY
310 320 330 340 350 360
290 300 310 320 330 340
pF1KB8 DGDELGLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSD
. .: .. .. .:.:.: .:.::::..: ::
XP_006 EDEEAAVVQYNDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDD
370 380 390 400 410 420
350 360
pF1KB8 GWCEGVSSEGTGFFPGNYVEPSC
XP_006 GWYEGVCNRVTGLFPGNYVESIMHYTD
430 440
>>NP_001012770 (OMIM: 603050) abl interactor 1 isoform d (476 aa)
initn: 882 init1: 606 opt: 686 Z-score: 319.4 bits: 68.1 E(85289): 4.7e-11
Smith-Waterman score: 686; 44.1% identity (70.6% similar) in 272 aa overlap (1-264:1-271)
10 20 30 40 50 60
pF1KB8 MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKQKALEETMAFTTQALAS
:::::.: : :::.:..:: ... : :::::::.::.:::::.:::::: :.:::.:::
NP_001 MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPP
::::.. ::...:..::.:.. ::..:. .. ..: :..: ::::::::: :.: .
NP_001 VAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSR
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 GQKVIAPENLPPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRK---SIKAPATP
.:.::: :. . : :.:... :::.:::.: ..: .::::::: . : :. :
NP_001 THKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKHGNNQPARTGTLSRTNPPTQKPPSPP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 ASA--TLGR--PPRIPEPVHLPVVPDGRLSAASSASSLASAGSAEGVGGAP-TPKGQAAP
:. :::: : . :::. :.::. ... . .: : : . ... : : .:...
NP_001 MSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGG
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 PAPPLPSSLDPPPPPAAVEVFQRPPTLEELSPPPPDEELPLPLDLPPPPPLDGDELGLPP
. :. . : :: . :::. .:
NP_001 SGSRENSGSSSIGIPIAVPT-PSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSG
250 260 270 280 290
300 310 320 330 340 350
pF1KB8 PPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSE
NP_001 GYRRTPSVTAQFSAQPHVNGGPLYSQNSISIAPPPPPMPQLTPQIPLTGFVARVQENIAD
300 310 320 330 340 350
>--
initn: 290 init1: 290 opt: 388 Z-score: 192.6 bits: 44.6 E(85289): 0.00055
Smith-Waterman score: 388; 33.8% identity (59.5% similar) in 210 aa overlap (161-363:277-469)
140 150 160 170 180 190
pF1KB8 PPLTPYCRRPLNFGCLDDIGHGIKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPE
:. ::..:. . .: .:.. : : :
NP_001 SGSSSIGIPIAVPTPSPPTIGPAAPGSAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPS
250 260 270 280 290 300
200 210 220 230 240
pF1KB8 PVHLPVVPDGRLSAASSASSLASAGSAEGVGGAPTPKGQAAPPAPPLPSSLDPPPPPAA-
..: ::. ...: . .. . ::: ::.:. : : : ..
NP_001 -----------VTAQFSAQPHVNGGPLYSQNSI-----SIAPPPPPMPQ-LTPQIPLTGF
310 320 330 340
250 260 270 280 290 300
pF1KB8 -VEVFQRPPTLEELSPPPPDEELPLPLDLPPPPP-----LDGDELGLPPPPPGFGPDEPS
..: . :::: ...:. : ::::: . .: .. .. .:.
NP_001 VARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYNDPYADGDPA
350 360 370 380 390 400
310 320 330 340 350 360
pF1KB8 WVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVE
:.: .:.::::..: ::..::.:::: ::..: : .. .::: ::: .. ::.:::::::
NP_001 WAPKNYIEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPGNYVE
410 420 430 440 450 460
pF1KB8 PSC
NP_001 SIMHYTD
470
366 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:46:28 2016 done: Fri Nov 4 11:46:29 2016
Total Scan time: 7.910 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]