Result of FASTA (ccds) for
pF1KB8318
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8318, 247 aa
1>>>pF1KB8318 247 - 247 aa - 247 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1660+/-0.00066; mu= 15.4296+/- 0.040
mean_var=67.0719+/-13.214, 0's: 0 Z-trim(110.8): 20 B-trim: 0 in 0/51
Lambda= 0.156604
statistics sampled from 11892 (11909) to 11892 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.747), E-opt: 0.2 (0.366), width: 16
Scan time: 2.070
The best scores are: opt bits E(32554)
CCDS14767.1 CLIC2 gene_id:1193|Hs108|chrX ( 247) 1666 384.7 3.2e-107
CCDS256.1 CLIC4 gene_id:25932|Hs108|chr1 ( 253) 1090 254.5 4.8e-68
CCDS4914.1 CLIC5 gene_id:53405|Hs108|chr6 ( 251) 1086 253.6 9e-68
CCDS13638.1 CLIC6 gene_id:54102|Hs108|chr21 ( 686) 1090 254.8 1.1e-67
CCDS47438.1 CLIC5 gene_id:53405|Hs108|chr6 ( 410) 1080 252.4 3.4e-67
CCDS82669.1 CLIC6 gene_id:54102|Hs108|chr21 ( 704) 1071 250.5 2.2e-66
CCDS4719.1 CLIC1 gene_id:1192|Hs108|chr6 ( 241) 959 224.9 3.8e-59
CCDS59022.1 CLIC5 gene_id:53405|Hs108|chr6 ( 205) 839 197.8 4.8e-51
CCDS7021.1 CLIC3 gene_id:9022|Hs108|chr9 ( 236) 785 185.6 2.5e-47
>>CCDS14767.1 CLIC2 gene_id:1193|Hs108|chrX (247 aa)
initn: 1666 init1: 1666 opt: 1666 Z-score: 2038.5 bits: 384.7 E(32554): 3.2e-107
Smith-Waterman score: 1666; 100.0% identity (100.0% similar) in 247 aa overlap (1-247:1-247)
10 20 30 40 50 60
pF1KB8 MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 LKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 SAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 LADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYA
190 200 210 220 230 240
pF1KB8 NVAKQKS
:::::::
CCDS14 NVAKQKS
>>CCDS256.1 CLIC4 gene_id:25932|Hs108|chr1 (253 aa)
initn: 1094 init1: 1076 opt: 1090 Z-score: 1335.0 bits: 254.5 E(32554): 4.8e-68
Smith-Waterman score: 1090; 64.1% identity (86.9% similar) in 245 aa overlap (1-245:7-250)
10 20 30 40 50
pF1KB8 MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDM
..::. . .: ::::::::::::::::::: :::::::::::: :.:::::.
CCDS25 MALSMPLNGLKEEDK-EPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDL
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 TRKPEELKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGC
::: .:..:::::.:::...:.:.::: :::::::..: ::.: .::::. :: .:
CCDS25 KRKPADLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 NLFAKFSAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFL
..::::::::::.. :::. .:..::: ...::.:::.:: :::: .: :. : : ::
CCDS25 DIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPDEIDENSMEDIKFSTRKFL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 DGDQLTLADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKE
::...:::::.:::::.:.::.:::::.:::: :..:.:::: :::.:.:::.::: :::
CCDS25 DGNEMTLADCNLLPKLHIVKVVAKKYRNFDIPKEMTGIWRYLTNAYSRDEFTNTCPSDKE
180 190 200 210 220 230
240
pF1KB8 IENTYANVAKQKS
.: .:..:::.
CCDS25 VEIAYSDVAKRLTK
240 250
>>CCDS4914.1 CLIC5 gene_id:53405|Hs108|chr6 (251 aa)
initn: 1147 init1: 1082 opt: 1086 Z-score: 1330.2 bits: 253.6 E(32554): 9e-68
Smith-Waterman score: 1086; 65.6% identity (86.7% similar) in 241 aa overlap (7-247:9-249)
10 20 30 40 50
pF1KB8 MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKP
: . ::::::::::: :::::::::: :::::::::::: :::::::. :::
CCDS49 MTDSATANGDDRDPEIELFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 EELKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFA
.:..:::::.::::..: ..::: :::::::.::.: .::.:. :..:: .: ..:.
CCDS49 ADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 KFSAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQ
:::::::::... : .:..: : .:.::::::::: .::: .. : ::: :::::.
CCDS49 KFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 LTLADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENT
::::::.:::::...:..:::::..:::::..:.::::.:::::.:::.:: :.::: .
CCDS49 LTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWRYLKNAYARDEFTNTCAADSEIELA
190 200 210 220 230 240
240
pF1KB8 YANVAKQKS
::.:::. :
CCDS49 YADVAKRLSRS
250
>>CCDS13638.1 CLIC6 gene_id:54102|Hs108|chr21 (686 aa)
initn: 1131 init1: 1084 opt: 1090 Z-score: 1328.7 bits: 254.8 E(32554): 1.1e-67
Smith-Waterman score: 1090; 67.4% identity (89.3% similar) in 233 aa overlap (13-245:452-684)
10 20 30 40
pF1KB8 MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWL
.: :::::: :::::::::: :::::::::
CCDS13 PAEGSGEAARVNGRREDGEASEPRALGQEHDITLFVKAGYDGESIGNCPFSQRLFMILWL
430 440 450 460 470 480
50 60 70 80 90 100
pF1KB8 KGVKFNVTTVDMTRKPEELKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHL
::: :::::::. ::: .:..:::::::::.... :.::: :::::::. :::::::.:
CCDS13 KGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKL
490 500 510 520 530 540
110 120 130 140 150 160
pF1KB8 SPKYKESFDVGCNLFAKFSAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDS
. .. :: ..: ..::::::.::::.:.::. ::.::: ...::.:::.:: :::: :
CCDS13 GTQHPESNSAGNDVFAKFSAFIKNTKKDANEIHEKNLLKALRKLDNYLNSPLPDEIDAYS
550 560 570 580 590 600
170 180 190 200 210 220
pF1KB8 AEEPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAR
.:. :: : :::::.::::::.:::::.:::..:::::::..:.:..:.::::.:::::
CCDS13 TEDVTVSGRKFLDGDELTLADCNLLPKLHIIKIVAKKYRDFEFPSEMTGIWRYLNNAYAR
610 620 630 640 650 660
230 240
pF1KB8 EEFTHTCPEDKEIENTYANVAKQKS
.:::.::: :.:::..:..:::.
CCDS13 DEFTNTCPADQEIEHAYSDVAKRMK
670 680
>>CCDS47438.1 CLIC5 gene_id:53405|Hs108|chr6 (410 aa)
initn: 1131 init1: 1066 opt: 1080 Z-score: 1319.8 bits: 252.4 E(32554): 3.4e-67
Smith-Waterman score: 1080; 64.2% identity (86.8% similar) in 243 aa overlap (5-247:166-408)
10 20 30
pF1KB8 MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQ
. :....::: :::::: :::::::::: :
CCDS47 PSPSSFTIQHSKAFSTTKYSCYSDAEGLEEKEGAHMNPEIYLFVKAGIDGESIGNCPFSQ
140 150 160 170 180 190
40 50 60 70 80 90
pF1KB8 RLFMILWLKGVKFNVTTVDMTRKPEELKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTL
::::::::::: :::::::. ::: .:..:::::.::::..: ..::: :::::::.::
CCDS47 RLFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETL
200 210 220 230 240 250
100 110 120 130 140 150
pF1KB8 APPRYPHLSPKYKESFDVGCNLFAKFSAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPL
.: .::.:. :..:: .: ..:.:::::::::... : .:..: : .:.:::::::::
CCDS47 TPEKYPKLAAKHRESNTAGIDIFSKFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPL
260 270 280 290 300 310
160 170 180 190 200 210
pF1KB8 LDEIDPDSAEEPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWR
.::: .. : ::: :::::.::::::.:::::...:..:::::..:::::..:.::
CCDS47 PEEIDANTCGEDKGSRRKFLDGDELTLADCNLLPKLHVVKIVAKKYRNYDIPAEMTGLWR
320 330 340 350 360 370
220 230 240
pF1KB8 YLHNAYAREEFTHTCPEDKEIENTYANVAKQKS
::.:::::.:::.:: :.::: .::.:::. :
CCDS47 YLKNAYARDEFTNTCAADSEIELAYADVAKRLSRS
380 390 400 410
>>CCDS82669.1 CLIC6 gene_id:54102|Hs108|chr21 (704 aa)
initn: 1107 init1: 1060 opt: 1071 Z-score: 1305.4 bits: 250.5 E(32554): 2.2e-66
Smith-Waterman score: 1071; 65.9% identity (89.2% similar) in 232 aa overlap (14-245:471-702)
10 20 30 40
pF1KB8 MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLK
:. ...:: :::::::::: ::::::::::
CCDS82 ASEPRALGQEHDITLFVKVKLTALGCSRIAIKKYLRAGYDGESIGNCPFSQRLFMILWLK
450 460 470 480 490 500
50 60 70 80 90 100
pF1KB8 GVKFNVTTVDMTRKPEELKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLS
:: :::::::. ::: .:..:::::::::.... :.::: :::::::. :::::::.:.
CCDS82 GVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGEVKTDVNKIEEFLEEKLAPPRYPKLG
510 520 530 540 550 560
110 120 130 140 150 160
pF1KB8 PKYKESFDVGCNLFAKFSAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSA
.. :: ..: ..::::::.::::.:.::. ::.::: ...::.:::.:: :::: :.
CCDS82 TQHPESNSAGNDVFAKFSAFIKNTKKDANEIHEKNLLKALRKLDNYLNSPLPDEIDAYST
570 580 590 600 610 620
170 180 190 200 210 220
pF1KB8 EEPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYARE
:. :: : :::::.::::::.:::::.:::..:::::::..:.:..:.::::.:::::.
CCDS82 EDVTVSGRKFLDGDELTLADCNLLPKLHIIKIVAKKYRDFEFPSEMTGIWRYLNNAYARD
630 640 650 660 670 680
230 240
pF1KB8 EFTHTCPEDKEIENTYANVAKQKS
:::.::: :.:::..:..:::.
CCDS82 EFTNTCPADQEIEHAYSDVAKRMK
690 700
>>CCDS4719.1 CLIC1 gene_id:1192|Hs108|chr6 (241 aa)
initn: 959 init1: 959 opt: 959 Z-score: 1175.4 bits: 224.9 E(32554): 3.8e-59
Smith-Waterman score: 959; 62.2% identity (80.3% similar) in 233 aa overlap (12-244:6-238)
10 20 30 40 50 60
pF1KB8 MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEE
:..:::::::::: .:::::: :::::.:::::: ::::::: :. :
CCDS47 MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTET
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 LKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKF
.. : :: . :::.:. :..:: ::::::: .: :::::.:. :: .: ..::::
CCDS47 VQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 SAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQLT
::::::.. : :.::.::: .: ::.::..:: .:.: :::. ::.: ::::..::
CCDS47 SAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELT
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 LADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENTYA
::::.:::::.:..:. :::: : :: : :: ::: ::::::::. :::.:.::: .:
CCDS47 LADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYE
180 190 200 210 220 230
pF1KB8 NVAKQKS
.:::
CCDS47 QVAKALK
240
>>CCDS59022.1 CLIC5 gene_id:53405|Hs108|chr6 (205 aa)
initn: 869 init1: 835 opt: 839 Z-score: 1029.9 bits: 197.8 E(32554): 4.8e-51
Smith-Waterman score: 839; 65.4% identity (85.1% similar) in 188 aa overlap (7-194:9-196)
10 20 30 40 50
pF1KB8 MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKP
: . ::::::::::: :::::::::: :::::::::::: :::::::. :::
CCDS59 MTDSATANGDDRDPEIELFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 EELKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFA
.:..:::::.::::..: ..::: :::::::.::.: .::.:. :..:: .: ..:.
CCDS59 ADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPKLAAKHRESNTAGIDIFS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 KFSAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPVSRRLFLDGDQ
:::::::::... : .:..: : .:.::::::::: .::: .. : ::: :::::.
CCDS59 KFSAYIKNTKQQNNAALERGLTKALKKLDDYLNTPLPEEIDANTCGEDKGSRRKFLDGDE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 LTLADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENT
::::::.:::::...:
CCDS59 LTLADCNLLPKLHVVKEQVPLKGMI
190 200
>>CCDS7021.1 CLIC3 gene_id:9022|Hs108|chr9 (236 aa)
initn: 779 init1: 530 opt: 785 Z-score: 963.1 bits: 185.6 E(32554): 2.5e-47
Smith-Waterman score: 785; 51.5% identity (77.9% similar) in 231 aa overlap (11-239:3-229)
10 20 30 40 50 60
pF1KB8 MSGLRPGTQVDPEIELFVKAGSDGESIGNCPFCQRLFMILWLKGVKFNVTTVDMTRKPEE
. ...:::::. ::::.:.:: ::::::.: :::: :..:::: :.:.
CCDS70 MAETKLQLFVKASEDGESVGHCPSCQRLFMVLLLKGVPFTLTTVDTRRSPDV
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 LKDLAPGTNPPFLVYNKELKTDFIKIEEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKF
:::.:::.. :.:.:... ::: ..::.:::.::.:: .: :.:.:.:: .: ..: ::
CCDS70 LKDFAPGSQLPILLYDSDAKTDTLQIEDFLEETLGPPDFPSLAPRYRESNTAGNDVFHKF
60 70 80 90 100 110
130 140 150 160 170
pF1KB8 SAYIKNTQKEANKNFEKSLLKEFKRLDDYLNTPLLDEIDPDSAEEPPV--SRRLFLDGDQ
::.::: .. . ..::. . :::.:: .:: :. : :: . ::: :::::.
CCDS70 SAFIKNPVPAQDEALYQQLLRALARLDSYLRAPLEHEL----AGEPQLRESRRRFLDGDR
120 130 140 150 160
180 190 200 210 220 230
pF1KB8 LTLADCSLLPKLNIIKVAAKKYRDFDIPAEFSGVWRYLHNAYAREEFTHTCPEDKEIENT
::::::::::::.:. .. ..:. ::::. :: ::: .:. ..:: .:::.. :: .
CCDS70 LTLADCSLLPKLHIVDTVCAHFRQAPIPAELRGVRRYLDSAMQEKEFKYTCPHSAEILAA
170 180 190 200 210 220
240
pF1KB8 YANVAKQKS
:
CCDS70 YRPAVHPR
230
247 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:42:15 2016 done: Fri Nov 4 11:42:15 2016
Total Scan time: 2.070 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]