FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8315, 254 aa
  1>>>pF1KB8315 254 - 254 aa - 254 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.3997+/-0.000315; mu= 10.0804+/- 0.020
 mean_var=101.5258+/-20.569, 0's: 0 Z-trim(118.8): 8  B-trim: 537 in 1/52
 Lambda= 0.127288
 statistics sampled from 32071 (32079) to 32071 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.741), E-opt: 0.2 (0.376), width:  16
 Scan time:  6.750

The best scores are:                                      opt bits E(85289)
NP_000108 (OMIM: 300384,310300) emerin [Homo sapie ( 254) 1690 320.2 2.2e-87
XP_005269189 (OMIM: 188380,613740) PREDICTED: thym ( 382)  220 50.4 5.7e-06


>>NP_000108 (OMIM: 300384,310300) emerin [Homo sapiens]   (254 aa)
 initn: 1690 init1: 1690 opt: 1690  Z-score: 1689.7  bits: 320.2 E(85289): 2.2e-87
Smith-Waterman score: 1690; 100.0% identity (100.0% similar) in 254 aa overlap (1-254:1-254)

               10        20        30        40        50        60
pF1KB8 MDNYADLSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIFEYETQRRRLSPPSSSAASSYS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MDNYADLSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIFEYETQRRRLSPPSSSAASSYS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 FSDLNSTRGDADMYDLPKKEDALLYQSKGYNDDYYEESYFTTRTYGEPESAGPSRAVRQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FSDLNSTRGDADMYDLPKKEDALLYQSKGYNDDYYEESYFTTRTYGEPESAGPSRAVRQS
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 VTSFPDADAFHHQVHDDDLLSSSEEECKDRERPMYGRDSAYQSITHYRPVSASRSSLDLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VTSFPDADAFHHQVHDDDLLSSSEEECKDRERPMYGRDSAYQSITHYRPVSASRSSLDLS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 YYPTSSSTSFMSSSSSSSSWLTRRAIRPENRAPGAGLGQDRQVPLWGQLLLFLVFVIVLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YYPTSSSTSFMSSSSSSSSWLTRRAIRPENRAPGAGLGQDRQVPLWGQLLLFLVFVIVLF
              190       200       210       220       230       240

              250    
pF1KB8 FIYHFMQAEEGNPF
       ::::::::::::::
NP_000 FIYHFMQAEEGNPF
              250    

>>XP_005269189 (OMIM: 188380,613740) PREDICTED: thymopoi  (382 aa)
 initn: 225 init1: 120 opt: 220  Z-score: 228.2  bits: 50.4 E(85289): 5.7e-06
Smith-Waterman score: 228; 24.6% identity (55.4% similar) in 276 aa overlap (3-254:111-370)

                                           10        20        30  
pF1KB8                             MDNYADLSDTELTTLLRRYNIPHGPVVGSTRR
                                     . ..:.. .:   : .:..  ::.::.::.
XP_005 AAAAGRSRAAVGRKATKKTDKPRQEDKDDLDVTELTNEDLLDQLVKYGVNPGPIVGTTRK
               90       100       110       120       130       140

             40          50        60        70        80          
pF1KB8 LYEKKIFEYETQ--RRRLSPPSSSAASSYSFSDLNSTRGDADMYDLPKKEDALLYQS---
       :::::... . :  . : : :  . .::   .  :.. .:.: :.  ..::. .  .   
XP_005 LYEKKLLKLREQGTESRSSTPLPTISSSAENTRQNGS-NDSDRYS-DNEEDSKIELKLEK
              150       160       170        180        190        

            90              100       110       120         130    
pF1KB8 ----KGY-------NDDYYEESYFTTRTYGEPESAGPSRAVRQSVTSFPDAD--AFHHQV
           ::        ..   :..  ..:. :. . :.:       .: : :    : .. .
XP_005 REPLKGRAKTPVTLKQRRVEHNQVVNRVTGNFKHASPI----LPITEFSDIPRRAPKKPL
      200       210       220       230           240       250    

          140       150         160          170        180        
pF1KB8 HDDDLLSSSEEECKDRE--RPMYGRDSAYQ---SITHYRPVS-ASRSSLDLSYYPTSSST
          ..  ..::.  .:.  . :.  ...     : .  ::.. :.   :.::        
XP_005 TRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELS--------
          260       270       280       290       300              

      190       200       210       220       230       240        
pF1KB8 SFMSSSSSSSSWLTRRAIRPENRAPGAGLGQDRQVPLWGQLLLFLVFVIVLFFIYHFMQA
       .:    : ::... . .  :   . .    . :..:.: ..:::.: .. ::..:. :..
XP_005 DFRMEESFSSKYVPKYV--PLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMET
        310       320         330       340       350       360    

      250                
pF1KB8 EEGNPF            
       .. :::            
XP_005 NQVNPFSNFLHVDPRKSN
          370       380  




254 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 11:40:53 2016 done: Fri Nov  4 11:40:54 2016
 Total Scan time:  6.750 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]