Result of FASTA (omim) for
pF1KB8311
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8311, 117 aa
1>>>pF1KB8311 117 - 117 aa - 117 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7557+/-0.000318; mu= 12.8108+/- 0.020
mean_var=53.0782+/-10.617, 0's: 0 Z-trim(113.6): 17 B-trim: 0 in 0/57
Lambda= 0.176042
statistics sampled from 23010 (23027) to 23010 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.67), E-opt: 0.2 (0.27), width: 16
Scan time: 3.360
The best scores are: opt bits E(85289)
NP_009216 (OMIM: 607452) gamma-aminobutyric acid r ( 117) 776 204.5 3.1e-53
NP_113600 (OMIM: 607420) gamma-aminobutyric acid r ( 117) 479 129.1 1.6e-30
NP_009209 (OMIM: 605125) gamma-aminobutyric acid r ( 117) 462 124.8 3.2e-29
XP_005253401 (OMIM: 607420) PREDICTED: gamma-amino ( 146) 405 110.4 8.7e-25
NP_115903 (OMIM: 601242) microtubule-associated pr ( 121) 332 91.8 2.8e-19
XP_011527387 (OMIM: 601242) PREDICTED: microtubule ( 182) 332 91.9 4e-19
XP_011527385 (OMIM: 601242) PREDICTED: microtubule ( 223) 332 91.9 4.7e-19
XP_011527386 (OMIM: 601242) PREDICTED: microtubule ( 223) 332 91.9 4.7e-19
NP_852610 (OMIM: 601242) microtubule-associated pr ( 125) 314 87.2 6.9e-18
NP_073729 (OMIM: 609604) microtubule-associated pr ( 125) 307 85.4 2.4e-17
NP_001004343 (OMIM: 609605) microtubule-associated ( 147) 306 85.2 3.2e-17
XP_005273196 (OMIM: 609605) PREDICTED: microtubule ( 147) 306 85.2 3.2e-17
>>NP_009216 (OMIM: 607452) gamma-aminobutyric acid recep (117 aa)
initn: 776 init1: 776 opt: 776 Z-score: 1076.7 bits: 204.5 E(85289): 3.1e-53
Smith-Waterman score: 776; 100.0% identity (100.0% similar) in 117 aa overlap (1-117:1-117)
10 20 30 40 50 60
pF1KB8 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQF
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 MWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF
70 80 90 100 110
>>NP_113600 (OMIM: 607420) gamma-aminobutyric acid recep (117 aa)
initn: 514 init1: 479 opt: 479 Z-score: 669.0 bits: 129.1 E(85289): 1.6e-30
Smith-Waterman score: 479; 61.2% identity (86.2% similar) in 116 aa overlap (1-116:1-116)
10 20 30 40 50 60
pF1KB8 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQF
::...:::: .:.: :. ::: ::::::::::::. ... :.::::::::::.::.::
NP_113 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQF
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 MWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF
...:::::.: : :.:.::..:.: .: ::::::: ...:: ::::::: :...:
NP_113 YFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK
70 80 90 100 110
>>NP_009209 (OMIM: 605125) gamma-aminobutyric acid recep (117 aa)
initn: 483 init1: 462 opt: 462 Z-score: 645.7 bits: 124.8 E(85289): 3.2e-29
Smith-Waterman score: 462; 57.3% identity (88.0% similar) in 117 aa overlap (1-117:1-117)
10 20 30 40 50 60
pF1KB8 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQF
::...::.: .:.: :. ::: ::::::::::::. ..: :.::.:::::::.::.::
NP_009 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQF
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 MWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF
...:::::.: .: :.:.::....: .: ::::::.....:: :::.::: :...:.
NP_009 YFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
70 80 90 100 110
>>XP_005253401 (OMIM: 607420) PREDICTED: gamma-aminobuty (146 aa)
initn: 405 init1: 405 opt: 405 Z-score: 566.0 bits: 110.4 E(85289): 8.7e-25
Smith-Waterman score: 405; 62.5% identity (86.5% similar) in 96 aa overlap (1-96:1-96)
10 20 30 40 50 60
pF1KB8 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQF
::...:::: .:.: :. ::: ::::::::::::. ... :.::::::::::.::.::
XP_005 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQF
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 MWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF
...:::::.: : :.:.::..:.: .: :::::::
XP_005 YFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEVMVLVAQYWMPSSAVWHPLALVLD
70 80 90 100 110 120
XP_005 ALITHLRSGAEGVIYPDPLTYGSVRL
130 140
>>NP_115903 (OMIM: 601242) microtubule-associated protei (121 aa)
initn: 328 init1: 127 opt: 332 Z-score: 467.0 bits: 91.8 E(85289): 2.8e-19
Smith-Waterman score: 332; 41.7% identity (80.9% similar) in 115 aa overlap (5-117:7-121)
10 20 30 40 50
pF1KB8 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSG-SQIVDIDKRKYLVPSDITV
::. .:. :: : .:: ..:...:::.:. .: .:. .:: :.:::. ...
NP_115 MPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 AQFMWIIRKRIQLPSEKAIFLFVDK-TVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFG
.... :::.:.:: .:.::.:.. .. . : ....::.:::::::::..:....:::
NP_115 SELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFG
70 80 90 100 110 120
pF1KB8 F
:
NP_115 F
>>XP_011527387 (OMIM: 601242) PREDICTED: microtubule-ass (182 aa)
initn: 328 init1: 127 opt: 332 Z-score: 464.4 bits: 91.9 E(85289): 4e-19
Smith-Waterman score: 332; 41.7% identity (80.9% similar) in 115 aa overlap (5-117:68-182)
10 20 30
pF1KB8 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVE
::. .:. :: : .:: ..:...:::.:
XP_011 RSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIE
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB8 KVSG-SQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDK-TVPQSSLTMG
. .: .:. .:: :.:::. ....... :::.:.:: .:.::.:.. .. . : ..
XP_011 RYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIA
100 110 120 130 140 150
100 110
pF1KB8 QLYEKEKDEDGFLYVAYSGENTFGF
..::.:::::::::..:....::::
XP_011 DIYEQEKDEDGFLYMVYASQETFGF
160 170 180
>>XP_011527385 (OMIM: 601242) PREDICTED: microtubule-ass (223 aa)
initn: 328 init1: 127 opt: 332 Z-score: 463.0 bits: 91.9 E(85289): 4.7e-19
Smith-Waterman score: 332; 41.7% identity (80.9% similar) in 115 aa overlap (5-117:109-223)
10 20 30
pF1KB8 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVE
::. .:. :: : .:: ..:...:::.:
XP_011 RSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIE
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB8 KVSG-SQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDK-TVPQSSLTMG
. .: .:. .:: :.:::. ....... :::.:.:: .:.::.:.. .. . : ..
XP_011 RYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIA
140 150 160 170 180 190
100 110
pF1KB8 QLYEKEKDEDGFLYVAYSGENTFGF
..::.:::::::::..:....::::
XP_011 DIYEQEKDEDGFLYMVYASQETFGF
200 210 220
>>XP_011527386 (OMIM: 601242) PREDICTED: microtubule-ass (223 aa)
initn: 328 init1: 127 opt: 332 Z-score: 463.0 bits: 91.9 E(85289): 4.7e-19
Smith-Waterman score: 332; 41.7% identity (80.9% similar) in 115 aa overlap (5-117:109-223)
10 20 30
pF1KB8 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVE
::. .:. :: : .:: ..:...:::.:
XP_011 RSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIE
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB8 KVSG-SQIVDIDKRKYLVPSDITVAQFMWIIRKRIQLPSEKAIFLFVDK-TVPQSSLTMG
. .: .:. .:: :.:::. ....... :::.:.:: .:.::.:.. .. . : ..
XP_011 RYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIA
140 150 160 170 180 190
100 110
pF1KB8 QLYEKEKDEDGFLYVAYSGENTFGF
..::.:::::::::..:....::::
XP_011 DIYEQEKDEDGFLYMVYASQETFGF
200 210 220
>>NP_852610 (OMIM: 601242) microtubule-associated protei (125 aa)
initn: 310 init1: 127 opt: 314 Z-score: 442.1 bits: 87.2 E(85289): 6.9e-18
Smith-Waterman score: 314; 42.5% identity (82.1% similar) in 106 aa overlap (14-117:20-125)
10 20 30 40 50
pF1KB8 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSG-SQIVDIDKRKYLVPS
:: : .:: ..:...:::.:. .: .:. .:: :.:::.
NP_852 MKMRFFSSPCGKAAVDPADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 DITVAQFMWIIRKRIQLPSEKAIFLFVDK-TVPQSSLTMGQLYEKEKDEDGFLYVAYSGE
....... :::.:.:: .:.::.:.. .. . : ....::.:::::::::..:...
NP_852 HVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQ
70 80 90 100 110 120
pF1KB8 NTFGF
.::::
NP_852 ETFGF
>>NP_073729 (OMIM: 609604) microtubule-associated protei (125 aa)
initn: 303 init1: 118 opt: 307 Z-score: 432.5 bits: 85.4 E(85289): 2.4e-17
Smith-Waterman score: 307; 39.5% identity (81.6% similar) in 114 aa overlap (5-116:7-120)
10 20 30 40 50
pF1KB8 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSG-SQIVDIDKRKYLVPSDITV
::. ...:.: . :: ..: ..:::.:. .: .:. .:: :.:::. ...
NP_073 MPSEKTFKQRRTFEQRVEDVRLIREQHPTKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 AQFMWIIRKRIQLPSEKAIFLFVD-KTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFG
.... :::.:.:: ...:.::.:. ... . : ....::.:::::::::..:....:::
NP_073 SELIKIIRRRLQLNANQAFFLLVNGHSMVSVSTPISEVYESEKDEDGFLYMVYASQETFG
70 80 90 100 110 120
pF1KB8 F
NP_073 MKLSV
117 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:37:43 2016 done: Fri Nov 4 11:37:43 2016
Total Scan time: 3.360 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]