FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8291, 472 aa
  1>>>pF1KB8291 472 - 472 aa - 472 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.3974+/-0.000829; mu= 6.1220+/- 0.051
 mean_var=181.8947+/-36.448, 0's: 0 Z-trim(114.2): 42  B-trim: 89 in 1/52
 Lambda= 0.095096
 statistics sampled from 14763 (14804) to 14763 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.455), width:  16
 Scan time:  1.880

The best scores are:                                      opt bits E(32554)
CCDS41730.1 PKNOX2 gene_id:63876|Hs108|chr11       ( 472) 3133 441.6 8.2e-124
CCDS68211.1 PKNOX1 gene_id:5316|Hs108|chr21        ( 319)  951 142.2 7.9e-34
CCDS13692.1 PKNOX1 gene_id:5316|Hs108|chr21        ( 436)  794 120.7 3.1e-27


>>CCDS41730.1 PKNOX2 gene_id:63876|Hs108|chr11            (472 aa)
 initn: 3133 init1: 3133 opt: 3133  Z-score: 2336.3  bits: 441.6 E(32554): 8.2e-124
Smith-Waterman score: 3133; 100.0% identity (100.0% similar) in 472 aa overlap (1-472:1-472)

               10        20        30        40        50        60
pF1KB8 MMQHASPAPALTMMATQNVPPPPYQDSPQMTATAQPPSKAQAVHISAPSAAASTPVPSAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MMQHASPAPALTMMATQNVPPPPYQDSPQMTATAQPPSKAQAVHISAPSAAASTPVPSAP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 IDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 IDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 KPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 KPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 GGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 GGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 GALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 GALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHAT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 NIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 NIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 KAKKIKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDSATMAMQQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 KAKKIKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDSATMAMQQA
              370       380       390       400       410       420

              430       440       450       460       470  
pF1KB8 MMAAHDDSLDGTEEEDEDEMEEEEEEELEEEVDELQTTNVSDLGLEHSDSLE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MMAAHDDSLDGTEEEDEDEMEEEEEEELEEEVDELQTTNVSDLGLEHSDSLE
              430       440       450       460       470  

>>CCDS68211.1 PKNOX1 gene_id:5316|Hs108|chr21             (319 aa)
 initn: 1110 init1: 457 opt: 951  Z-score: 720.8  bits: 142.2 E(32554): 7.9e-34
Smith-Waterman score: 1209; 58.5% identity (79.0% similar) in 352 aa overlap (134-472:1-319)

           110       120       130       140       150       160   
pF1KB8 SFDVDIENFVHQQEQEHKPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYI
                                     ::::::::::::::::::::::::::.:::
CCDS68                               MVKAIQVLRIHLLELEKVNELCKDFCSRYI
                                             10        20        30

           170       180       190       200       210       220   
pF1KB8 TCLKTKMHSDNLLRNDLGGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASAL
       .::::::.:..:: .. :.:::: :      ::..     ....: . .:::::::::::
CCDS68 ACLKTKMNSETLLSGEPGSPYSPVQ------SQQI----QSAITG-TISPQGIVVPASAL
               40        50                  60         70         

           230       240       250       260       270          280
pF1KB8 QQGNIAMTTVNSQVVSGGALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLT---SL
       ::::.::.::     .::..:::::.:: :::::::..  :.:.:::.:..:.:.   :.
CCDS68 QQGNVAMATV-----AGGTVYQPVTVVTPQGQVVTQTLSPGTIRIQNSQLQLQLNQDLSI
      80             90       100       110       120       130    

              290       300       310       320       330       340
pF1KB8 LDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFI
       : ..: .::::::::::::::.::::::::. :::::::::.::::::::::::::::::
CCDS68 LHQDDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFI
          140       150       160       170       180       190    

              350       360       370       380               390  
pF1KB8 NARRRILQPMLDASNPDPAPKAKKIKSQHRPTQRFWPNSIAAGVLQ--------QQGGAP
       ::::::::::::.:  . .::.::  .:.::.:::::.:::.:: :        ..:.. 
CCDS68 NARRRILQPMLDSSCSE-TPKTKKKTAQNRPVQRFWPDSIASGVAQPPPSELTMSEGAVV
          200       210        220       230       240       250   

            400       410       420         430       440       450
pF1KB8 GTNPDGSINLDNLQSLSSDSATMAMQQAMMAAH--DDSLDGTEEEDEDEMEEEEEEELEE
         .   ..:.:.:::::::.::.:.::.:::..  :.:.:.:::                
CCDS68 TITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEE----------------
           260       270       280       290                       

              460       470  
pF1KB8 EVDELQTTNVSDLGLEHSDSLE
       ..  :  ...: : ::.::::.
CCDS68 DAGALAPAHISGLVLENSDSLQ
       300       310         

>>CCDS13692.1 PKNOX1 gene_id:5316|Hs108|chr21             (436 aa)
 initn: 1540 init1: 675 opt: 794  Z-score: 602.5  bits: 120.7 E(32554): 3.1e-27
Smith-Waterman score: 1650; 58.1% identity (79.1% similar) in 473 aa overlap (13-472:1-436)

               10        20        30        40        50        60
pF1KB8 MMQHASPAPALTMMATQNVPPPPYQDSPQMTATAQPPSKAQAVHISAPSAAASTPVPSAP
                   :::::..    :::. :: ....  .. :  . : :.: . .: :  :
CCDS13             MMATQTLSIDSYQDGQQMQVVTELKTE-QDPNCSEPDAEGVSP-P--P
                           10        20         30        40       

               70        80        90       100       110       120
pF1KB8 IDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEH
       .. :. ...::.:.:::::::::.::::::::.:::::  :::::::::::::..::.: 
CCDS13 VESQTPMDVDKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKEG
           50        60        70        80        90       100    

              130       140       150       160       170       180
pF1KB8 KPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDL
       :::: .::: :::::::::::::::::::::::::::::.:::.::::::.:..:: .. 
CCDS13 KPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEP
          110       120       130       140       150       160    

              190       200       210       220       230       240
pF1KB8 GGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSG
       :.:::: :      ::..     ....: . .:::::::::::::::.::.::     .:
CCDS13 GSPYSPVQ------SQQI----QSAITG-TISPQGIVVPASALQQGNVAMATV-----AG
          170                 180        190       200             

              250       260       270          280       290       
pF1KB8 GALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLT---SLLDNEDKKSKNKRGVLPK
       :..:::::.:: :::::::..  :.:.:::.:..:.:.   :.: ..: .::::::::::
CCDS13 GTVYQPVTVVTPQGQVVTQTLSPGTIRIQNSQLQLQLNQDLSILHQDDGSSKNKRGVLPK
      210       220       230       240       250       260        

       300       310       320       330       340       350       
pF1KB8 HATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPD
       ::::.::::::::. :::::::::.::::::::::::::::::::::::::::::.:  .
CCDS13 HATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSE
      270       280       290       300       310       320        

       360       370       380               390       400         
pF1KB8 PAPKAKKIKSQHRPTQRFWPNSIAAGVLQ--------QQGGAPGTNPDGSINLDNLQSLS
        .::.::  .:.::.:::::.:::.:: :        ..:..   .   ..:.:.:::::
CCDS13 -TPKTKKKTAQNRPVQRFWPDSIASGVAQPPPSELTMSEGAVVTITTPVNMNVDSLQSLS
       330       340       350       360       370       380       

     410       420         430       440       450       460       
pF1KB8 SDSATMAMQQAMMAAH--DDSLDGTEEEDEDEMEEEEEEELEEEVDELQTTNVSDLGLEH
       ::.::.:.::.:::..  :.:.:.:::.                .  :  ...: : ::.
CCDS13 SDGATLAVQQVMMAGQSEDESVDSTEED----------------AGALAPAHISGLVLEN
       390       400       410                       420       430 

       470  
pF1KB8 SDSLE
       ::::.
CCDS13 SDSLQ
            




472 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 11:26:26 2016 done: Fri Nov  4 11:26:27 2016
 Total Scan time:  1.880 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]