Result of FASTA (omim) for
pF1KB8288
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8288, 407 aa
1>>>pF1KB8288 407 - 407 aa - 407 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.2181+/-0.000362; mu= -6.6845+/- 0.022
mean_var=224.1123+/-45.766, 0's: 0 Z-trim(120.8): 141 B-trim: 0 in 0/59
Lambda= 0.085672
statistics sampled from 36411 (36559) to 36411 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.429), width: 16
Scan time: 8.720
The best scores are: opt bits E(85289)
XP_006719338 (OMIM: 600247) PREDICTED: ETS domain- ( 407) 2642 339.2 1.1e-92
NP_005221 (OMIM: 600247) ETS domain-containing pro ( 407) 2642 339.2 1.1e-92
XP_005245007 (OMIM: 600246) PREDICTED: ETS domain- ( 431) 753 105.7 2.3e-22
NP_001964 (OMIM: 600246) ETS domain-containing pro ( 431) 753 105.7 2.3e-22
XP_005245008 (OMIM: 600246) PREDICTED: ETS domain- ( 431) 753 105.7 2.3e-22
XP_016856069 (OMIM: 600246) PREDICTED: ETS domain- ( 413) 751 105.5 2.6e-22
NP_068567 (OMIM: 600246) ETS domain-containing pro ( 405) 741 104.2 6e-22
NP_001290440 (OMIM: 600247) ETS domain-containing ( 83) 493 73.3 2.5e-13
NP_005220 (OMIM: 311040) ETS domain-containing pro ( 428) 495 73.8 8.9e-13
XP_016884828 (OMIM: 311040) PREDICTED: ETS domain- ( 428) 495 73.8 8.9e-13
NP_001107595 (OMIM: 311040) ETS domain-containing ( 428) 495 73.8 8.9e-13
NP_001244097 (OMIM: 311040) ETS domain-containing ( 95) 474 71.0 1.4e-12
NP_001248368 (OMIM: 600711) ETS translocation vari ( 207) 367 57.9 2.7e-08
XP_011522816 (OMIM: 600711) PREDICTED: ETS translo ( 221) 367 57.9 2.9e-08
NP_001248366 (OMIM: 600711) ETS translocation vari ( 445) 367 58.0 5.3e-08
NP_001248367 (OMIM: 600711) ETS translocation vari ( 445) 367 58.0 5.3e-08
XP_016879838 (OMIM: 600711) PREDICTED: ETS translo ( 479) 367 58.0 5.7e-08
NP_001977 (OMIM: 600711) ETS translocation variant ( 484) 367 58.0 5.7e-08
NP_001073143 (OMIM: 600711) ETS translocation vari ( 484) 367 58.0 5.7e-08
NP_001257941 (OMIM: 193067) Friend leukemia integr ( 259) 360 57.0 6e-08
NP_001257939 (OMIM: 193067) Friend leukemia integr ( 386) 360 57.1 8.6e-08
XP_011541004 (OMIM: 193067) PREDICTED: Friend leuk ( 410) 360 57.1 9e-08
XP_011541003 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 360 57.1 9.2e-08
XP_016872895 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 360 57.1 9.2e-08
NP_001161153 (OMIM: 193067) Friend leukemia integr ( 419) 360 57.1 9.2e-08
XP_016872894 (OMIM: 193067) PREDICTED: Friend leuk ( 419) 360 57.1 9.2e-08
NP_002008 (OMIM: 193067) Friend leukemia integrati ( 452) 360 57.1 9.8e-08
NP_004445 (OMIM: 601600) ETS translocation variant ( 510) 361 57.3 1e-07
NP_001156624 (OMIM: 600541) ETS translocation vari ( 374) 354 56.4 1.4e-07
NP_001230358 (OMIM: 165080) transcriptional regula ( 363) 353 56.2 1.5e-07
NP_001156623 (OMIM: 600541) ETS translocation vari ( 419) 354 56.4 1.5e-07
NP_001129627 (OMIM: 165080) transcriptional regula ( 387) 353 56.3 1.6e-07
NP_001156622 (OMIM: 600541) ETS translocation vari ( 437) 354 56.4 1.6e-07
NP_001156619 (OMIM: 600541) ETS translocation vari ( 454) 354 56.4 1.7e-07
NP_001156621 (OMIM: 600541) ETS translocation vari ( 459) 354 56.4 1.7e-07
NP_001156620 (OMIM: 600541) ETS translocation vari ( 459) 354 56.4 1.7e-07
XP_011513472 (OMIM: 600541) PREDICTED: ETS translo ( 472) 354 56.4 1.7e-07
XP_016883778 (OMIM: 165080) PREDICTED: transcripti ( 428) 353 56.3 1.7e-07
XP_005249693 (OMIM: 600541) PREDICTED: ETS translo ( 477) 354 56.4 1.7e-07
XP_011513470 (OMIM: 600541) PREDICTED: ETS translo ( 477) 354 56.4 1.7e-07
NP_004947 (OMIM: 600541) ETS translocation variant ( 477) 354 56.4 1.7e-07
XP_005249692 (OMIM: 600541) PREDICTED: ETS translo ( 477) 354 56.4 1.7e-07
XP_011527788 (OMIM: 165080) PREDICTED: transcripti ( 435) 353 56.3 1.7e-07
XP_011513469 (OMIM: 600541) PREDICTED: ETS translo ( 491) 354 56.4 1.8e-07
NP_001317954 (OMIM: 165080) transcriptional regula ( 455) 353 56.3 1.8e-07
XP_016883776 (OMIM: 165080) PREDICTED: transcripti ( 459) 353 56.3 1.8e-07
NP_004440 (OMIM: 165080) transcriptional regulator ( 462) 353 56.3 1.8e-07
NP_891548 (OMIM: 165080) transcriptional regulator ( 479) 353 56.3 1.9e-07
NP_001230357 (OMIM: 165080) transcriptional regula ( 486) 353 56.3 1.9e-07
NP_001129626 (OMIM: 165080) transcriptional regula ( 486) 353 56.3 1.9e-07
>>XP_006719338 (OMIM: 600247) PREDICTED: ETS domain-cont (407 aa)
initn: 2642 init1: 2642 opt: 2642 Z-score: 1784.9 bits: 339.2 E(85289): 1.1e-92
Smith-Waterman score: 2642; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407)
10 20 30 40 50 60
pF1KB8 MESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAVEISRESLLLQDSDCKASPEGRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAVEISRESLLLQDSDCKASPEGRE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AHKHGLAALRSTSRNEYIHSGLYSSFTINSLQNPPDAFKAIKTEKLEEPPEDSPPVEEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AHKHGLAALRSTSRNEYIHSGLYSSFTINSLQNPPDAFKAIKTEKLEEPPEDSPPVEEVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 TVIRFVTNKTDKHVTRPVVSLPSTSEAAAASAFLASSVSAKISSLMLPNAASISSASPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVIRFVTNKTDKHVTRPVVSLPSTSEAAAASAFLASSVSAKISSLMLPNAASISSASPFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SRSPSLSPNSPLPSEHRSLFLEAACHDSDSLEPLNLSSGSKTKSPSLPPKAKKPKGLEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SRSPSLSPNSPLPSEHRSLFLEAACHDSDSLEPLNLSSGSKTKSPSLPPKAKKPKGLEIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 APPLVLSGTDIGSIALNSPALPSGSLTPAFFTAQTPNGLLLTPSPLLSSIHFWSSLSPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APPLVLSGTDIGSIALNSPALPSGSLTPAFFTAQTPNGLLLTPSPLLSSIHFWSSLSPVA
310 320 330 340 350 360
370 380 390 400
pF1KB8 PLSPARLQGPSTLFQFPTLLNGHMPVPIPSLDRAASPVLLSSNSQKS
:::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLSPARLQGPSTLFQFPTLLNGHMPVPIPSLDRAASPVLLSSNSQKS
370 380 390 400
>>NP_005221 (OMIM: 600247) ETS domain-containing protein (407 aa)
initn: 2642 init1: 2642 opt: 2642 Z-score: 1784.9 bits: 339.2 E(85289): 1.1e-92
Smith-Waterman score: 2642; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407)
10 20 30 40 50 60
pF1KB8 MESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAVEISRESLLLQDSDCKASPEGRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAVEISRESLLLQDSDCKASPEGRE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AHKHGLAALRSTSRNEYIHSGLYSSFTINSLQNPPDAFKAIKTEKLEEPPEDSPPVEEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AHKHGLAALRSTSRNEYIHSGLYSSFTINSLQNPPDAFKAIKTEKLEEPPEDSPPVEEVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 TVIRFVTNKTDKHVTRPVVSLPSTSEAAAASAFLASSVSAKISSLMLPNAASISSASPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TVIRFVTNKTDKHVTRPVVSLPSTSEAAAASAFLASSVSAKISSLMLPNAASISSASPFS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SRSPSLSPNSPLPSEHRSLFLEAACHDSDSLEPLNLSSGSKTKSPSLPPKAKKPKGLEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SRSPSLSPNSPLPSEHRSLFLEAACHDSDSLEPLNLSSGSKTKSPSLPPKAKKPKGLEIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 APPLVLSGTDIGSIALNSPALPSGSLTPAFFTAQTPNGLLLTPSPLLSSIHFWSSLSPVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 APPLVLSGTDIGSIALNSPALPSGSLTPAFFTAQTPNGLLLTPSPLLSSIHFWSSLSPVA
310 320 330 340 350 360
370 380 390 400
pF1KB8 PLSPARLQGPSTLFQFPTLLNGHMPVPIPSLDRAASPVLLSSNSQKS
:::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PLSPARLQGPSTLFQFPTLLNGHMPVPIPSLDRAASPVLLSSNSQKS
370 380 390 400
>>XP_005245007 (OMIM: 600246) PREDICTED: ETS domain-cont (431 aa)
initn: 1139 init1: 533 opt: 753 Z-score: 522.7 bits: 105.7 E(85289): 2.3e-22
Smith-Waterman score: 1199; 50.9% identity (71.6% similar) in 436 aa overlap (1-407:1-431)
10 20 30 40 50 60
pF1KB8 MESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLS
:.::::::::::::: ...:.::::::::.::::.:::::.:::.:::: ::::::::
XP_005 MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLS
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 RALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAV---EISRESLLLQD-SDCKASP
::::::: ::::::: ::::::::::.::::.::: .: : . ::: ... :. . .
XP_005 RALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMTVGRIEGDCESLNFSEVSSSSKDV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 EGREAHKHGLAALRSTSRNEYIHSGLYSSFTINSLQNPP-DAFKAIKTEK-LEEPPEDSP
:. : . ...:::.:::::::::::.:::.. :: ::::. :. : .
XP_005 ENGGKDKPPQPGAKTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKTENPAEKLAEKKS
130 140 150 160 170 180
180 190 200 210 220
pF1KB8 PVEEVRTVIRFVTNKTDKHVTRPV---VSL-PSTSEAAAASA-FLASSVSAKISSLMLPN
: : . .::.:::. . : ..:: .:. :: : .. . : . :: :. :: :.
XP_005 PQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSSEETIQALETLVSPKLPSLEAPT
190 200 210 220 230 240
230 240 250 260 270
pF1KB8 AAS-----ISSASPFSS----RSPSLSPNSPLPSEHRSLFLEAACHDSDSLE-PLNLSSG
.:: .... :.:: . : .:. :: : : .. . :. .: : :::
XP_005 SASNVMTAFATTPPISSIPPLQEPPRTPSPPLSS-HPDIDTDIDSVASQPMELPENLSLE
250 260 270 280 290
280 290 300 310 320 330
pF1KB8 SKTKSPSLPPK--------AKKPKGLEISAPPLVLSGTDIGSIALNSPALPSGSLTPAFF
: .. : : .:::::::. :: ::....: . ... ::.::..:::::::
XP_005 PKDQDSVLLEKDKVNNSSRSKKPKGLEL-APTLVITSSDPSPLGILSPSLPTASLTPAFF
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB8 TAQTPNGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPSTLFQFPTLLNGHMPVPIPSL
. ::: ..::::::::::::::.:::::::::::::: .::::::..::.: : . .:
XP_005 S-QTP--IILTPSPLLSSIHFWSTLSPVAPLSPARLQGANTLFQFPSVLNSHGPFTLSGL
360 370 380 390 400 410
400
pF1KB8 DRAASPVLLSSNSQKS
: ..: .: . ::.
XP_005 DGPSTPGPFSPDLQKT
420 430
>>NP_001964 (OMIM: 600246) ETS domain-containing protein (431 aa)
initn: 1139 init1: 533 opt: 753 Z-score: 522.7 bits: 105.7 E(85289): 2.3e-22
Smith-Waterman score: 1199; 50.9% identity (71.6% similar) in 436 aa overlap (1-407:1-431)
10 20 30 40 50 60
pF1KB8 MESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLS
:.::::::::::::: ...:.::::::::.::::.:::::.:::.:::: ::::::::
NP_001 MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLS
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 RALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAV---EISRESLLLQD-SDCKASP
::::::: ::::::: ::::::::::.::::.::: .: : . ::: ... :. . .
NP_001 RALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMTVGRIEGDCESLNFSEVSSSSKDV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 EGREAHKHGLAALRSTSRNEYIHSGLYSSFTINSLQNPP-DAFKAIKTEK-LEEPPEDSP
:. : . ...:::.:::::::::::.:::.. :: ::::. :. : .
NP_001 ENGGKDKPPQPGAKTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKTENPAEKLAEKKS
130 140 150 160 170 180
180 190 200 210 220
pF1KB8 PVEEVRTVIRFVTNKTDKHVTRPV---VSL-PSTSEAAAASA-FLASSVSAKISSLMLPN
: : . .::.:::. . : ..:: .:. :: : .. . : . :: :. :: :.
NP_001 PQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSSEETIQALETLVSPKLPSLEAPT
190 200 210 220 230 240
230 240 250 260 270
pF1KB8 AAS-----ISSASPFSS----RSPSLSPNSPLPSEHRSLFLEAACHDSDSLE-PLNLSSG
.:: .... :.:: . : .:. :: : : .. . :. .: : :::
NP_001 SASNVMTAFATTPPISSIPPLQEPPRTPSPPLSS-HPDIDTDIDSVASQPMELPENLSLE
250 260 270 280 290
280 290 300 310 320 330
pF1KB8 SKTKSPSLPPK--------AKKPKGLEISAPPLVLSGTDIGSIALNSPALPSGSLTPAFF
: .. : : .:::::::. :: ::....: . ... ::.::..:::::::
NP_001 PKDQDSVLLEKDKVNNSSRSKKPKGLEL-APTLVITSSDPSPLGILSPSLPTASLTPAFF
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB8 TAQTPNGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPSTLFQFPTLLNGHMPVPIPSL
. ::: ..::::::::::::::.:::::::::::::: .::::::..::.: : . .:
NP_001 S-QTP--IILTPSPLLSSIHFWSTLSPVAPLSPARLQGANTLFQFPSVLNSHGPFTLSGL
360 370 380 390 400 410
400
pF1KB8 DRAASPVLLSSNSQKS
: ..: .: . ::.
NP_001 DGPSTPGPFSPDLQKT
420 430
>>XP_005245008 (OMIM: 600246) PREDICTED: ETS domain-cont (431 aa)
initn: 1139 init1: 533 opt: 753 Z-score: 522.7 bits: 105.7 E(85289): 2.3e-22
Smith-Waterman score: 1199; 50.9% identity (71.6% similar) in 436 aa overlap (1-407:1-431)
10 20 30 40 50 60
pF1KB8 MESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLS
:.::::::::::::: ...:.::::::::.::::.:::::.:::.:::: ::::::::
XP_005 MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLS
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 RALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAV---EISRESLLLQD-SDCKASP
::::::: ::::::: ::::::::::.::::.::: .: : . ::: ... :. . .
XP_005 RALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMTVGRIEGDCESLNFSEVSSSSKDV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 EGREAHKHGLAALRSTSRNEYIHSGLYSSFTINSLQNPP-DAFKAIKTEK-LEEPPEDSP
:. : . ...:::.:::::::::::.:::.. :: ::::. :. : .
XP_005 ENGGKDKPPQPGAKTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKTENPAEKLAEKKS
130 140 150 160 170 180
180 190 200 210 220
pF1KB8 PVEEVRTVIRFVTNKTDKHVTRPV---VSL-PSTSEAAAASA-FLASSVSAKISSLMLPN
: : . .::.:::. . : ..:: .:. :: : .. . : . :: :. :: :.
XP_005 PQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSSEETIQALETLVSPKLPSLEAPT
190 200 210 220 230 240
230 240 250 260 270
pF1KB8 AAS-----ISSASPFSS----RSPSLSPNSPLPSEHRSLFLEAACHDSDSLE-PLNLSSG
.:: .... :.:: . : .:. :: : : .. . :. .: : :::
XP_005 SASNVMTAFATTPPISSIPPLQEPPRTPSPPLSS-HPDIDTDIDSVASQPMELPENLSLE
250 260 270 280 290
280 290 300 310 320 330
pF1KB8 SKTKSPSLPPK--------AKKPKGLEISAPPLVLSGTDIGSIALNSPALPSGSLTPAFF
: .. : : .:::::::. :: ::....: . ... ::.::..:::::::
XP_005 PKDQDSVLLEKDKVNNSSRSKKPKGLEL-APTLVITSSDPSPLGILSPSLPTASLTPAFF
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB8 TAQTPNGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPSTLFQFPTLLNGHMPVPIPSL
. ::: ..::::::::::::::.:::::::::::::: .::::::..::.: : . .:
XP_005 S-QTP--IILTPSPLLSSIHFWSTLSPVAPLSPARLQGANTLFQFPSVLNSHGPFTLSGL
360 370 380 390 400 410
400
pF1KB8 DRAASPVLLSSNSQKS
: ..: .: . ::.
XP_005 DGPSTPGPFSPDLQKT
420 430
>>XP_016856069 (OMIM: 600246) PREDICTED: ETS domain-cont (413 aa)
initn: 1058 init1: 533 opt: 751 Z-score: 521.6 bits: 105.5 E(85289): 2.6e-22
Smith-Waterman score: 1118; 51.7% identity (71.7% similar) in 406 aa overlap (1-378:1-402)
10 20 30 40 50 60
pF1KB8 MESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLS
:.::::::::::::: ...:.::::::::.::::.:::::.:::.:::: ::::::::
XP_016 MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLS
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 RALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAV---EISRESLLLQD-SDCKASP
::::::: ::::::: ::::::::::.::::.::: .: : . ::: ... :. . .
XP_016 RALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMTVGRIEGDCESLNFSEVSSSSKDV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 EGREAHKHGLAALRSTSRNEYIHSGLYSSFTINSLQNPP-DAFKAIKTEK-LEEPPEDSP
:. : . ...:::.:::::::::::.:::.. :: ::::. :. : .
XP_016 ENGGKDKPPQPGAKTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKTENPAEKLAEKKS
130 140 150 160 170 180
180 190 200 210 220
pF1KB8 PVEEVRTVIRFVTNKTDKHVTRPV---VSL-PSTSEAAAASA-FLASSVSAKISSLMLPN
: : . .::.:::. . : ..:: .:. :: : .. . : . :: :. :: :.
XP_016 PQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSSEETIQALETLVSPKLPSLEAPT
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB8 AAS-----ISSASPFSSRSP-SLSPNSPLP--SEHRSLFLEAACHDSDSLE-PLNLSSGS
.:: .... :.:: : . : .: : : : .. . :. .: : :::
XP_016 SASNVMTAFATTPPISSIPPLQEPPRTPSPPLSSHPDIDTDIDSVASQPMELPENLSLEP
250 260 270 280 290 300
290 300 310 320 330
pF1KB8 KTKSPSLPPK--------AKKPKGLEISAPPLVLSGTDIGSIALNSPALPSGSLTPAFFT
: .. : : .:::::::. :: ::....: . ... ::.::..:::::::.
XP_016 KDQDSVLLEKDKVNNSSRSKKPKGLEL-APTLVITSSDPSPLGILSPSLPTASLTPAFFS
310 320 330 340 350
340 350 360 370 380 390
pF1KB8 AQTPNGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPSTLFQFPTLLNGHMPVPIPSLD
::: ..::::::::::::::.:::::::::::::: .::::. .
XP_016 -QTP--IILTPSPLLSSIHFWSTLSPVAPLSPARLQGANTLFQMESSPCHPGWSAVA
360 370 380 390 400 410
400
pF1KB8 RAASPVLLSSNSQKS
>>NP_068567 (OMIM: 600246) ETS domain-containing protein (405 aa)
initn: 850 init1: 533 opt: 741 Z-score: 515.1 bits: 104.2 E(85289): 6e-22
Smith-Waterman score: 921; 48.4% identity (69.6% similar) in 378 aa overlap (1-350:1-375)
10 20 30 40 50 60
pF1KB8 MESAITLWQFLLQLLLDQKHEHLICWTSNDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLS
:.::::::::::::: ...:.::::::::.::::.:::::.:::.:::: ::::::::
NP_068 MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLS
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 RALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMDPHAV---EISRESLLLQD-SDCKASP
::::::: ::::::: ::::::::::.::::.::: .: : . ::: ... :. . .
NP_068 RALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMTVGRIEGDCESLNFSEVSSSSKDV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 EGREAHKHGLAALRSTSRNEYIHSGLYSSFTINSLQNPP-DAFKAIKTEK-LEEPPEDSP
:. : . ...:::.:::::::::::.:::.. :: ::::. :. : .
NP_068 ENGGKDKPPQPGAKTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKTENPAEKLAEKKS
130 140 150 160 170 180
180 190 200 210 220
pF1KB8 PVEEVRTVIRFVTNKTDKHVTRPV---VSL-PSTSEAAAASA-FLASSVSAKISSLMLPN
: : . .::.:::. . : ..:: .:. :: : .. . : . :: :. :: :.
NP_068 PQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSSEETIQALETLVSPKLPSLEAPT
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB8 AAS-----ISSASPFSSRSP-SLSPNSPLP--SEHRSLFLEAACHDSDSLE-PLNLSSGS
.:: .... :.:: : . : .: : : : .. . :. .: : :::
NP_068 SASNVMTAFATTPPISSIPPLQEPPRTPSPPLSSHPDIDTDIDSVASQPMELPENLSLEP
250 260 270 280 290 300
290 300 310 320 330
pF1KB8 KTKSPSLPPK--------AKKPKGLEISAPPLVLSGTDIGSIALNSPALPSGSLTPAFFT
: .. : : .:::::::. :: ::....: . ... ::.::..:::::::.
NP_068 KDQDSVLLEKDKVNNSSRSKKPKGLEL-APTLVITSSDPSPLGILSPSLPTASLTPAFFS
310 320 330 340 350
340 350 360 370 380 390
pF1KB8 AQTPNGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPSTLFQFPTLLNGHMPVPIPSLD
:. .:... ::::: :
NP_068 -QVACSLFMV-SPLLSFICPFKQIQNLYTQVCFLLLRFVLERLCVTVM
360 370 380 390 400
>>NP_001290440 (OMIM: 600247) ETS domain-containing prot (83 aa)
initn: 493 init1: 493 opt: 493 Z-score: 360.2 bits: 73.3 E(85289): 2.5e-13
Smith-Waterman score: 493; 97.4% identity (98.7% similar) in 76 aa overlap (332-407:8-83)
310 320 330 340 350 360
pF1KB8 PPLVLSGTDIGSIALNSPALPSGSLTPAFFTAQTPNGLLLTPSPLLSSIHFWSSLSPVAP
. ::::::::::::::::::::::::::::
NP_001 MRKAQDTSKQTPNGLLLTPSPLLSSIHFWSSLSPVAP
10 20 30
370 380 390 400
pF1KB8 LSPARLQGPSTLFQFPTLLNGHMPVPIPSLDRAASPVLLSSNSQKS
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSPARLQGPSTLFQFPTLLNGHMPVPIPSLDRAASPVLLSSNSQKS
40 50 60 70 80
>>NP_005220 (OMIM: 311040) ETS domain-containing protein (428 aa)
initn: 699 init1: 362 opt: 495 Z-score: 350.4 bits: 73.8 E(85289): 8.9e-13
Smith-Waterman score: 824; 38.6% identity (59.4% similar) in 438 aa overlap (1-406:1-427)
10 20 30 40 50
pF1KB8 MESAITLWQFLLQLLLDQKHEHLICWTSNDG-EFKLLKAEEVAKLWGLRKNKTNMNYDKL
:. ..:::::::::: .: . :.: ::: :: ::::. :::::.::::::::::::::::
NP_005 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 SRALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMD----PHAVEISRESLL--LQDSDCK
:::::::::::::.:: ::::::::::.::. . : :.: : . . . .
NP_005 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH
70 80 90 100 110 120
120 130 140 150 160
pF1KB8 ASPEGREAHKHGL---------AALRSTSRNEYIHSGLYSSFTINSLQN--PPDAFKAIK
:.: . : : ..: .:::::..:::::.:::.::: :: :.
NP_005 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSLQPQPPPHPRPAVV
130 140 150 160 170 180
170 180 190 200 210
pF1KB8 TEKLEEPPEDSPPVEEVRTV---IRFVTNKTDKHVTRPVVSLPST-----SEAAAASAFL
. .:: : .. . . . :. : :: . :
NP_005 LPSAAPAGAAAPPSGSRSTSPSPLEACLEAEEAGLPLQVILTPPEAPNLKSEELNVEPGL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB8 ASSVSAKISSLMLPNAASISSASPFSSRSPSLSPNSPLPSEHRSLFLEAACHDSDSLEPL
. .. ... . ... : .. . :. : :.: : :. :. .
NP_005 GRALPPEVKVEGPKEELEVAGERGFVPETTKAEPEVP-PQEGVPARLPAVVMDTAGQ---
250 260 270 280 290
280 290 300 310 320
pF1KB8 NLSSGSKTKSP--SLPPKAKKPKGLEISAPPLVLSGTDI----GSIALNSPALPSGSLTP
..: ..:: : : :..::. ::. : .:.: :: . .. :. .:::
NP_005 --AGGHAASSPEISQPQKGRKPRDLELPLSPSLLGGPGPERTPGSGSGSGLQAPGPALTP
300 310 320 330 340 350
330 340 350 360 370 380
pF1KB8 AFFTAQTPNGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPSTLFQFPTLLNGHMPVPI
... ..: . .::::: : ::::::.:::.:: :::.:. ::::. .... .:
NP_005 SLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLS-----FQFPSSGSAQVHIPS
360 370 380 390 400
390 400
pF1KB8 PSLDRAASPVLLSSNSQKS
:.: ..::.:: . ::
NP_005 ISVDGLSTPVVLSPGPQKP
410 420
>>XP_016884828 (OMIM: 311040) PREDICTED: ETS domain-cont (428 aa)
initn: 699 init1: 362 opt: 495 Z-score: 350.4 bits: 73.8 E(85289): 8.9e-13
Smith-Waterman score: 824; 38.6% identity (59.4% similar) in 438 aa overlap (1-406:1-427)
10 20 30 40 50
pF1KB8 MESAITLWQFLLQLLLDQKHEHLICWTSNDG-EFKLLKAEEVAKLWGLRKNKTNMNYDKL
:. ..:::::::::: .: . :.: ::: :: ::::. :::::.::::::::::::::::
XP_016 MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 SRALRYYYDKNIIKKVIGQKFVYKFVSFPEILKMD----PHAVEISRESLL--LQDSDCK
:::::::::::::.:: ::::::::::.::. . : :.: : . . . .
XP_016 SRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIH
70 80 90 100 110 120
120 130 140 150 160
pF1KB8 ASPEGREAHKHGL---------AALRSTSRNEYIHSGLYSSFTINSLQN--PPDAFKAIK
:.: . : : ..: .:::::..:::::.:::.::: :: :.
XP_016 AAPGDTVSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQSLQPQPPPHPRPAVV
130 140 150 160 170 180
170 180 190 200 210
pF1KB8 TEKLEEPPEDSPPVEEVRTV---IRFVTNKTDKHVTRPVVSLPST-----SEAAAASAFL
. .:: : .. . . . :. : :: . :
XP_016 LPSAAPAGAAAPPSGSRSTSPSPLEACLEAEEAGLPLQVILTPPEAPNLKSEELNVEPGL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB8 ASSVSAKISSLMLPNAASISSASPFSSRSPSLSPNSPLPSEHRSLFLEAACHDSDSLEPL
. .. ... . ... : .. . :. : :.: : :. :. .
XP_016 GRALPPEVKVEGPKEELEVAGERGFVPETTKAEPEVP-PQEGVPARLPAVVMDTAGQ---
250 260 270 280 290
280 290 300 310 320
pF1KB8 NLSSGSKTKSP--SLPPKAKKPKGLEISAPPLVLSGTDI----GSIALNSPALPSGSLTP
..: ..:: : : :..::. ::. : .:.: :: . .. :. .:::
XP_016 --AGGHAASSPEISQPQKGRKPRDLELPLSPSLLGGPGPERTPGSGSGSGLQAPGPALTP
300 310 320 330 340 350
330 340 350 360 370 380
pF1KB8 AFFTAQTPNGLLLTPSPLLSSIHFWSSLSPVAPLSPARLQGPSTLFQFPTLLNGHMPVPI
... ..: . .::::: : ::::::.:::.:: :::.:. ::::. .... .:
XP_016 SLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLS-----FQFPSSGSAQVHIPS
360 370 380 390 400
390 400
pF1KB8 PSLDRAASPVLLSSNSQKS
:.: ..::.:: . ::
XP_016 ISVDGLSTPVVLSPGPQKP
410 420
407 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:25:17 2016 done: Fri Nov 4 11:25:19 2016
Total Scan time: 8.720 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]