Result of FASTA (omim) for
pF1KB8243
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8243, 216 aa
1>>>pF1KB8243 216 - 216 aa - 216 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0059+/-0.000418; mu= 15.3026+/- 0.026
mean_var=79.0847+/-15.497, 0's: 0 Z-trim(112.9): 408 B-trim: 573 in 1/54
Lambda= 0.144221
statistics sampled from 21535 (22023) to 21535 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.258), width: 16
Scan time: 3.700
The best scores are: opt bits E(85289)
NP_006316 (OMIM: 601179) GTP-binding nuclear prote ( 216) 1462 313.7 1.5e-85
XP_016875261 (OMIM: 601179) PREDICTED: GTP-binding ( 222) 1377 296.0 3.1e-80
NP_001287725 (OMIM: 601179) GTP-binding nuclear pr ( 128) 866 189.5 2.1e-48
NP_001287726 (OMIM: 601179) GTP-binding nuclear pr ( 128) 866 189.5 2.1e-48
XP_016875262 (OMIM: 601179) PREDICTED: GTP-binding ( 134) 781 171.8 4.7e-43
NP_001272988 (OMIM: 605693) ras-related protein Ra ( 203) 359 84.2 1.7e-16
NP_001272990 (OMIM: 605693) ras-related protein Ra ( 203) 359 84.2 1.7e-16
NP_001272989 (OMIM: 605693) ras-related protein Ra ( 203) 359 84.2 1.7e-16
NP_055303 (OMIM: 605693) ras-related protein Rab-3 ( 203) 359 84.2 1.7e-16
NP_057215 (OMIM: 612672) ras-related protein Rab-1 ( 200) 356 83.6 2.6e-16
NP_004628 (OMIM: 600882,602298) ras-related protei ( 207) 352 82.7 4.7e-16
XP_011523393 (OMIM: 604037) PREDICTED: ras-related ( 216) 344 81.1 1.5e-15
NP_004574 (OMIM: 604037) ras-related protein Rab-5 ( 216) 344 81.1 1.5e-15
XP_011523392 (OMIM: 604037) PREDICTED: ras-related ( 216) 344 81.1 1.5e-15
NP_958842 (OMIM: 604037) ras-related protein Rab-5 ( 216) 344 81.1 1.5e-15
NP_001238968 (OMIM: 604037) ras-related protein Ra ( 249) 344 81.1 1.7e-15
NP_004569 (OMIM: 179511) ras-related protein Rab-4 ( 218) 343 80.9 1.8e-15
NP_004153 (OMIM: 179512) ras-related protein Rab-5 ( 215) 341 80.5 2.4e-15
NP_002861 (OMIM: 602672) ras-related protein Rab-1 ( 203) 339 80.0 3e-15
NP_067075 (OMIM: 602207,614222) ras-related protei ( 206) 338 79.8 3.6e-15
NP_002859 (OMIM: 179514) ras-related protein Rab-5 ( 215) 337 79.6 4.2e-15
XP_005269108 (OMIM: 179514) PREDICTED: ras-related ( 215) 337 79.6 4.2e-15
NP_001238965 (OMIM: 179514) ras-related protein Ra ( 215) 337 79.6 4.2e-15
XP_005269109 (OMIM: 179514) PREDICTED: ras-related ( 215) 337 79.6 4.2e-15
NP_057361 (OMIM: 201000,606144) ras-related protei ( 237) 337 79.7 4.5e-15
NP_001265597 (OMIM: 201000,606144) ras-related pro ( 237) 337 79.7 4.5e-15
NP_001265596 (OMIM: 201000,606144) ras-related pro ( 237) 337 79.7 4.5e-15
NP_001265595 (OMIM: 201000,606144) ras-related pro ( 237) 337 79.7 4.5e-15
NP_899050 (OMIM: 201000,606144) ras-related protei ( 237) 337 79.7 4.5e-15
XP_016885453 (OMIM: 300284) PREDICTED: ras-related ( 201) 336 79.4 4.7e-15
NP_001182257 (OMIM: 300284) ras-related protein Ra ( 201) 336 79.4 4.7e-15
NP_004242 (OMIM: 300284) ras-related protein Rab-9 ( 201) 336 79.4 4.7e-15
NP_006852 (OMIM: 604199) ras-related protein Rab-3 ( 201) 334 79.0 6.2e-15
NP_057454 (OMIM: 300285) ras-related protein Rab-9 ( 201) 333 78.8 7.2e-15
NP_112243 (OMIM: 612565) ras-related protein Rab-1 ( 201) 332 78.6 8.3e-15
NP_004152 (OMIM: 179508) ras-related protein Rab-1 ( 205) 327 77.5 1.7e-14
NP_057238 (OMIM: 612945) ras-related protein Rab-4 ( 213) 326 77.3 2.1e-14
NP_005361 (OMIM: 165040) ras-related protein Rab-8 ( 207) 321 76.3 4.1e-14
NP_057614 (OMIM: 613532) ras-related protein Rab-8 ( 207) 320 76.1 4.8e-14
XP_011526322 (OMIM: 165040) PREDICTED: ras-related ( 215) 320 76.1 4.9e-14
NP_004209 (OMIM: 604198) ras-related protein Rab-1 ( 218) 318 75.7 6.6e-14
NP_055814 (OMIM: 612398) ras-related protein Rab-2 ( 225) 315 75.1 1e-13
XP_016858700 (OMIM: 605412) PREDICTED: rab-like pr ( 235) 313 74.7 1.4e-13
XP_016858699 (OMIM: 605412) PREDICTED: rab-like pr ( 235) 313 74.7 1.4e-13
XP_016884039 (OMIM: 605413) PREDICTED: rab-like pr ( 235) 313 74.7 1.4e-13
XP_011528975 (OMIM: 605413) PREDICTED: rab-like pr ( 235) 313 74.7 1.4e-13
NP_057661 (OMIM: 615852) ras-related protein Rab-6 ( 208) 312 74.4 1.5e-13
NP_001304844 (OMIM: 612829) ras-related protein Ra ( 225) 312 74.4 1.6e-13
NP_612462 (OMIM: 612829) ras-related protein Rab-3 ( 227) 312 74.4 1.6e-13
XP_016884040 (OMIM: 605413) PREDICTED: rab-like pr ( 234) 312 74.5 1.7e-13
>>NP_006316 (OMIM: 601179) GTP-binding nuclear protein R (216 aa)
initn: 1462 init1: 1462 opt: 1462 Z-score: 1657.1 bits: 313.7 E(85289): 1.5e-85
Smith-Waterman score: 1462; 100.0% identity (100.0% similar) in 216 aa overlap (1-216:1-216)
10 20 30 40 50 60
pF1KB8 MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMP
130 140 150 160 170 180
190 200 210
pF1KB8 ALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
::::::::::::::::::::::::::::::::::::
NP_006 ALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
190 200 210
>>XP_016875261 (OMIM: 601179) PREDICTED: GTP-binding nuc (222 aa)
initn: 1377 init1: 1377 opt: 1377 Z-score: 1561.4 bits: 296.0 E(85289): 3.1e-80
Smith-Waterman score: 1377; 100.0% identity (100.0% similar) in 203 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KB8 MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 GNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMP
130 140 150 160 170 180
190 200 210
pF1KB8 ALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
:::::::::::::::::::::::
XP_016 ALAPPEVVMDPALAAQYEHDLEVLWPLCCSDCSVWLVYSWQF
190 200 210 220
>>NP_001287725 (OMIM: 601179) GTP-binding nuclear protei (128 aa)
initn: 866 init1: 866 opt: 866 Z-score: 989.8 bits: 189.5 E(85289): 2.1e-48
Smith-Waterman score: 866; 100.0% identity (100.0% similar) in 128 aa overlap (89-216:1-128)
60 70 80 90 100 110
pF1KB8 IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIV
::::::::::::::::::::::::::::::
NP_001 MFDVTSRVTYKNVPNWHRDLVRVCENIPIV
10 20 30
120 130 140 150 160 170
pF1KB8 LCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVA
40 50 60 70 80 90
180 190 200 210
pF1KB8 MPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
::::::::::::::::::::::::::::::::::::::
NP_001 MPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
100 110 120
>>NP_001287726 (OMIM: 601179) GTP-binding nuclear protei (128 aa)
initn: 866 init1: 866 opt: 866 Z-score: 989.8 bits: 189.5 E(85289): 2.1e-48
Smith-Waterman score: 866; 100.0% identity (100.0% similar) in 128 aa overlap (89-216:1-128)
60 70 80 90 100 110
pF1KB8 IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIV
::::::::::::::::::::::::::::::
NP_001 MFDVTSRVTYKNVPNWHRDLVRVCENIPIV
10 20 30
120 130 140 150 160 170
pF1KB8 LCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVA
40 50 60 70 80 90
180 190 200 210
pF1KB8 MPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
::::::::::::::::::::::::::::::::::::::
NP_001 MPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
100 110 120
>>XP_016875262 (OMIM: 601179) PREDICTED: GTP-binding nuc (134 aa)
initn: 781 init1: 781 opt: 781 Z-score: 894.0 bits: 171.8 E(85289): 4.7e-43
Smith-Waterman score: 781; 100.0% identity (100.0% similar) in 115 aa overlap (89-203:1-115)
60 70 80 90 100 110
pF1KB8 IKFNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIV
::::::::::::::::::::::::::::::
XP_016 MFDVTSRVTYKNVPNWHRDLVRVCENIPIV
10 20 30
120 130 140 150 160 170
pF1KB8 LCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVA
40 50 60 70 80 90
180 190 200 210
pF1KB8 MPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
:::::::::::::::::::::::::
XP_016 MPALAPPEVVMDPALAAQYEHDLEVLWPLCCSDCSVWLVYSWQF
100 110 120 130
>>NP_001272988 (OMIM: 605693) ras-related protein Rab-30 (203 aa)
initn: 339 init1: 256 opt: 359 Z-score: 417.1 bits: 84.2 E(85289): 1.7e-16
Smith-Waterman score: 359; 35.4% identity (66.5% similar) in 164 aa overlap (11-171:10-173)
10 20 30 40 50 60
pF1KB8 MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK
::.::.:..:.::: .:.: : : ::.::. . . : .:
NP_001 MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVK
10 20 30 40 50
70 80 90 100 110
pF1KB8 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCEN-IPIVL
...:::::::.: .. ..:: .:. :. .:.: . ... .:.: :.. . : . ::
NP_001 LQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 CGNKVDIKDRK--VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFV
:::.:. .:. . .. : . ... : . ::: . : :: :: :: .::..
NP_001 VGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTL
120 130 140 150 160 170
180 190 200 210
pF1KB8 AMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
NP_001 VNNVSSPLPGEGKSISYLTCCNFN
180 190 200
>>NP_001272990 (OMIM: 605693) ras-related protein Rab-30 (203 aa)
initn: 339 init1: 256 opt: 359 Z-score: 417.1 bits: 84.2 E(85289): 1.7e-16
Smith-Waterman score: 359; 35.4% identity (66.5% similar) in 164 aa overlap (11-171:10-173)
10 20 30 40 50 60
pF1KB8 MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK
::.::.:..:.::: .:.: : : ::.::. . . : .:
NP_001 MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVK
10 20 30 40 50
70 80 90 100 110
pF1KB8 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCEN-IPIVL
...:::::::.: .. ..:: .:. :. .:.: . ... .:.: :.. . : . ::
NP_001 LQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 CGNKVDIKDRK--VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFV
:::.:. .:. . .. : . ... : . ::: . : :: :: :: .::..
NP_001 VGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTL
120 130 140 150 160 170
180 190 200 210
pF1KB8 AMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
NP_001 VNNVSSPLPGEGKSISYLTCCNFN
180 190 200
>>NP_001272989 (OMIM: 605693) ras-related protein Rab-30 (203 aa)
initn: 339 init1: 256 opt: 359 Z-score: 417.1 bits: 84.2 E(85289): 1.7e-16
Smith-Waterman score: 359; 35.4% identity (66.5% similar) in 164 aa overlap (11-171:10-173)
10 20 30 40 50 60
pF1KB8 MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK
::.::.:..:.::: .:.: : : ::.::. . . : .:
NP_001 MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVK
10 20 30 40 50
70 80 90 100 110
pF1KB8 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCEN-IPIVL
...:::::::.: .. ..:: .:. :. .:.: . ... .:.: :.. . : . ::
NP_001 LQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 CGNKVDIKDRK--VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFV
:::.:. .:. . .. : . ... : . ::: . : :: :: :: .::..
NP_001 VGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTL
120 130 140 150 160 170
180 190 200 210
pF1KB8 AMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
NP_001 VNNVSSPLPGEGKSISYLTCCNFN
180 190 200
>>NP_055303 (OMIM: 605693) ras-related protein Rab-30 [H (203 aa)
initn: 339 init1: 256 opt: 359 Z-score: 417.1 bits: 84.2 E(85289): 1.7e-16
Smith-Waterman score: 359; 35.4% identity (66.5% similar) in 164 aa overlap (11-171:10-173)
10 20 30 40 50 60
pF1KB8 MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK
::.::.:..:.::: .:.: : : ::.::. . . : .:
NP_055 MSMEDYDFLFKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVK
10 20 30 40 50
70 80 90 100 110
pF1KB8 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCEN-IPIVL
...:::::::.: .. ..:: .:. :. .:.: . ... .:.: :.. . : . ::
NP_055 LQIWDTAGQERFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 CGNKVDIKDRK--VKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFV
:::.:. .:. . .. : . ... : . ::: . : :: :: :: .::..
NP_055 VGNKIDLAERREVSQQRAEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTL
120 130 140 150 160 170
180 190 200 210
pF1KB8 AMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
NP_055 VNNVSSPLPGEGKSISYLTCCNFN
180 190 200
>>NP_057215 (OMIM: 612672) ras-related protein Rab-10 [H (200 aa)
initn: 267 init1: 181 opt: 356 Z-score: 413.8 bits: 83.6 E(85289): 2.6e-16
Smith-Waterman score: 356; 34.3% identity (68.0% similar) in 175 aa overlap (11-177:10-184)
10 20 30 40 50 60
pF1KB8 MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK
:::.:.::.:.::: . : :. ...:.:.. . . . . ::
NP_057 MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIK
10 20 30 40 50
70 80 90 100 110
pF1KB8 FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDL-VRVCENIPIVL
...:::::::.: . .:: :. ....:.:. ...:. .: :.. .. :.. .:
NP_057 LQIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERML
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 CGNKVDIKDRKV--KAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLA----RKL-IGDP
::: :. :..: :.:. . :........ :::.: :.:: :: :: :: . .:
NP_057 LGNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEP
120 130 140 150 160 170
180 190 200 210
pF1KB8 NLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
: : :
NP_057 NSENVDISSGGGVTGWKSKCC
180 190 200
216 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:55:37 2016 done: Fri Nov 4 10:55:38 2016
Total Scan time: 3.700 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]