Result of FASTA (omim) for
pF1KB8228
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8228, 409 aa
1>>>pF1KB8228 409 - 409 aa - 409 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0243+/-0.0003; mu= 10.8848+/- 0.019
mean_var=149.0731+/-30.568, 0's: 0 Z-trim(120.9): 27 B-trim: 246 in 1/53
Lambda= 0.105045
statistics sampled from 36773 (36807) to 36773 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.432), width: 16
Scan time: 9.630
The best scores are: opt bits E(85289)
NP_057358 (OMIM: 608335) pleckstrin homology domai ( 409) 2698 420.2 4.5e-117
NP_001291651 (OMIM: 608335) pleckstrin homology do ( 237) 1540 244.5 2e-64
NP_001291652 (OMIM: 608335) pleckstrin homology do ( 237) 1540 244.5 2e-64
XP_016856909 (OMIM: 608335) PREDICTED: pleckstrin ( 237) 1540 244.5 2e-64
NP_001291653 (OMIM: 608335) pleckstrin homology do ( 226) 1477 235.0 1.5e-61
>>NP_057358 (OMIM: 608335) pleckstrin homology domain-co (409 aa)
initn: 2698 init1: 2698 opt: 2698 Z-score: 2222.8 bits: 420.2 E(85289): 4.5e-117
Smith-Waterman score: 2698; 100.0% identity (100.0% similar) in 409 aa overlap (1-409:1-409)
10 20 30 40 50 60
pF1KB8 MMKKNNSAKRGPQDGNQQPAPPEKVGWVRKFCGKGIFREIWKNRYVVLKGDQLYISEKEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MMKKNNSAKRGPQDGNQQPAPPEKVGWVRKFCGKGIFREIWKNRYVVLKGDQLYISEKEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 KDEKNIQEVFDLSDYEKCEELRKSKSRSKKNHSKFTLAHSKQPGNTAPNLIFLAVSPEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KDEKNIQEVFDLSDYEKCEELRKSKSRSKKNHSKFTLAHSKQPGNTAPNLIFLAVSPEEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ESWINALNSAITRAKNRILDEVTVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ESWINALNSAITRAKNRILDEVTVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTST
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 SDGMLTLDLIQEEDPSPEEPTSCAESFRVDLDKSVAQLAGSRRRADSDRIQPSADRASSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SDGMLTLDLIQEEDPSPEEPTSCAESFRVDLDKSVAQLAGSRRRADSDRIQPSADRASSL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SRPWEKTDKGATYTPQAPKKLTPTEKGRCASLEEILSQRDAASARTLQLRAEEPPTPALP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SRPWEKTDKGATYTPQAPKKLTPTEKGRCASLEEILSQRDAASARTLQLRAEEPPTPALP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NPGQLSRIQDLVARKLEETQELLAEVQGLGDGKRKAKDPPRSPPDSESEQLLLETERLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NPGQLSRIQDLVARKLEETQELLAEVQGLGDGKRKAKDPPRSPPDSESEQLLLETERLLG
310 320 330 340 350 360
370 380 390 400
pF1KB8 EASSNWSQAKRVLQEVRELRDLYRQMDLQTPDSHLRQTTPHSQYRKSLM
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EASSNWSQAKRVLQEVRELRDLYRQMDLQTPDSHLRQTTPHSQYRKSLM
370 380 390 400
>>NP_001291651 (OMIM: 608335) pleckstrin homology domain (237 aa)
initn: 1540 init1: 1540 opt: 1540 Z-score: 1277.5 bits: 244.5 E(85289): 2e-64
Smith-Waterman score: 1540; 100.0% identity (100.0% similar) in 237 aa overlap (173-409:1-237)
150 160 170 180 190 200
pF1KB8 TVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDPSPEEPTS
::::::::::::::::::::::::::::::
NP_001 MAVASTSTSDGMLTLDLIQEEDPSPEEPTS
10 20 30
210 220 230 240 250 260
pF1KB8 CAESFRVDLDKSVAQLAGSRRRADSDRIQPSADRASSLSRPWEKTDKGATYTPQAPKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAESFRVDLDKSVAQLAGSRRRADSDRIQPSADRASSLSRPWEKTDKGATYTPQAPKKLT
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB8 PTEKGRCASLEEILSQRDAASARTLQLRAEEPPTPALPNPGQLSRIQDLVARKLEETQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTEKGRCASLEEILSQRDAASARTLQLRAEEPPTPALPNPGQLSRIQDLVARKLEETQEL
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB8 LAEVQGLGDGKRKAKDPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAEVQGLGDGKRKAKDPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDL
160 170 180 190 200 210
390 400
pF1KB8 YRQMDLQTPDSHLRQTTPHSQYRKSLM
:::::::::::::::::::::::::::
NP_001 YRQMDLQTPDSHLRQTTPHSQYRKSLM
220 230
>>NP_001291652 (OMIM: 608335) pleckstrin homology domain (237 aa)
initn: 1540 init1: 1540 opt: 1540 Z-score: 1277.5 bits: 244.5 E(85289): 2e-64
Smith-Waterman score: 1540; 100.0% identity (100.0% similar) in 237 aa overlap (173-409:1-237)
150 160 170 180 190 200
pF1KB8 TVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDPSPEEPTS
::::::::::::::::::::::::::::::
NP_001 MAVASTSTSDGMLTLDLIQEEDPSPEEPTS
10 20 30
210 220 230 240 250 260
pF1KB8 CAESFRVDLDKSVAQLAGSRRRADSDRIQPSADRASSLSRPWEKTDKGATYTPQAPKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAESFRVDLDKSVAQLAGSRRRADSDRIQPSADRASSLSRPWEKTDKGATYTPQAPKKLT
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB8 PTEKGRCASLEEILSQRDAASARTLQLRAEEPPTPALPNPGQLSRIQDLVARKLEETQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTEKGRCASLEEILSQRDAASARTLQLRAEEPPTPALPNPGQLSRIQDLVARKLEETQEL
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB8 LAEVQGLGDGKRKAKDPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAEVQGLGDGKRKAKDPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDL
160 170 180 190 200 210
390 400
pF1KB8 YRQMDLQTPDSHLRQTTPHSQYRKSLM
:::::::::::::::::::::::::::
NP_001 YRQMDLQTPDSHLRQTTPHSQYRKSLM
220 230
>>XP_016856909 (OMIM: 608335) PREDICTED: pleckstrin homo (237 aa)
initn: 1540 init1: 1540 opt: 1540 Z-score: 1277.5 bits: 244.5 E(85289): 2e-64
Smith-Waterman score: 1540; 100.0% identity (100.0% similar) in 237 aa overlap (173-409:1-237)
150 160 170 180 190 200
pF1KB8 TVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDPSPEEPTS
::::::::::::::::::::::::::::::
XP_016 MAVASTSTSDGMLTLDLIQEEDPSPEEPTS
10 20 30
210 220 230 240 250 260
pF1KB8 CAESFRVDLDKSVAQLAGSRRRADSDRIQPSADRASSLSRPWEKTDKGATYTPQAPKKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CAESFRVDLDKSVAQLAGSRRRADSDRIQPSADRASSLSRPWEKTDKGATYTPQAPKKLT
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB8 PTEKGRCASLEEILSQRDAASARTLQLRAEEPPTPALPNPGQLSRIQDLVARKLEETQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTEKGRCASLEEILSQRDAASARTLQLRAEEPPTPALPNPGQLSRIQDLVARKLEETQEL
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB8 LAEVQGLGDGKRKAKDPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAEVQGLGDGKRKAKDPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDL
160 170 180 190 200 210
390 400
pF1KB8 YRQMDLQTPDSHLRQTTPHSQYRKSLM
:::::::::::::::::::::::::::
XP_016 YRQMDLQTPDSHLRQTTPHSQYRKSLM
220 230
>>NP_001291653 (OMIM: 608335) pleckstrin homology domain (226 aa)
initn: 1477 init1: 1477 opt: 1477 Z-score: 1226.2 bits: 235.0 E(85289): 1.5e-61
Smith-Waterman score: 1477; 100.0% identity (100.0% similar) in 226 aa overlap (184-409:1-226)
160 170 180 190 200 210
pF1KB8 TRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDPSPEEPTSCAESFRVDLDK
::::::::::::::::::::::::::::::
NP_001 MLTLDLIQEEDPSPEEPTSCAESFRVDLDK
10 20 30
220 230 240 250 260 270
pF1KB8 SVAQLAGSRRRADSDRIQPSADRASSLSRPWEKTDKGATYTPQAPKKLTPTEKGRCASLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVAQLAGSRRRADSDRIQPSADRASSLSRPWEKTDKGATYTPQAPKKLTPTEKGRCASLE
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB8 EILSQRDAASARTLQLRAEEPPTPALPNPGQLSRIQDLVARKLEETQELLAEVQGLGDGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EILSQRDAASARTLQLRAEEPPTPALPNPGQLSRIQDLVARKLEETQELLAEVQGLGDGK
100 110 120 130 140 150
340 350 360 370 380 390
pF1KB8 RKAKDPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDLYRQMDLQTPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKAKDPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDLYRQMDLQTPDS
160 170 180 190 200 210
400
pF1KB8 HLRQTTPHSQYRKSLM
::::::::::::::::
NP_001 HLRQTTPHSQYRKSLM
220
409 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:45:38 2016 done: Fri Nov 4 10:45:39 2016
Total Scan time: 9.630 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]