Result of FASTA (omim) for
pF1KB8220
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8220, 432 aa
1>>>pF1KB8220 432 - 432 aa - 432 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.0913+/-0.000599; mu= -9.7846+/- 0.037
mean_var=441.4222+/-90.304, 0's: 0 Z-trim(117.5): 179 B-trim: 339 in 1/55
Lambda= 0.061045
statistics sampled from 29340 (29527) to 29340 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.346), width: 16
Scan time: 9.280
The best scores are: opt bits E(85289)
NP_002046 (OMIM: 137780,203450) glial fibrillary a ( 432) 2701 252.7 1.4e-66
NP_001124491 (OMIM: 137780,203450) glial fibrillar ( 431) 2450 230.6 6.2e-60
XP_016879940 (OMIM: 137780,203450) PREDICTED: glia ( 472) 2450 230.6 6.6e-60
NP_001229305 (OMIM: 137780,203450) glial fibrillar ( 438) 2447 230.3 7.5e-60
XP_006717563 (OMIM: 116300,193060) PREDICTED: vime ( 466) 1608 156.5 1.4e-37
NP_003371 (OMIM: 116300,193060) vimentin [Homo sap ( 466) 1608 156.5 1.4e-37
NP_001918 (OMIM: 125660,181400,601419,602067,60476 ( 470) 1580 154.0 7.6e-37
NP_006253 (OMIM: 105400,170710) peripherin [Homo s ( 470) 1438 141.5 4.4e-33
XP_005269082 (OMIM: 105400,170710) PREDICTED: peri ( 471) 1426 140.4 9.2e-33
NP_116116 (OMIM: 605338) alpha-internexin [Homo sa ( 499) 1097 111.5 5.1e-24
NP_006149 (OMIM: 162280,607684,607734) neurofilame ( 543) 1045 106.9 1.3e-22
NP_005373 (OMIM: 162250) neurofilament medium poly ( 916) 1024 105.3 6.6e-22
XP_011528502 (OMIM: 105400,162230,616924) PREDICTE ( 924) 881 92.7 4.1e-18
NP_066554 (OMIM: 105400,162230,616924) neurofilame (1020) 881 92.8 4.4e-18
NP_001243222 (OMIM: 148060) keratin, type II cytos ( 483) 754 81.3 6.1e-15
NP_002264 (OMIM: 148060) keratin, type II cytoskel ( 483) 754 81.3 6.1e-15
XP_011536627 (OMIM: 148059) PREDICTED: keratin, ty ( 445) 753 81.1 6.2e-15
NP_001243211 (OMIM: 148060) keratin, type II cytos ( 511) 754 81.3 6.4e-15
NP_005547 (OMIM: 148059) keratin, type II cytoskel ( 469) 751 81.0 7.2e-15
NP_004684 (OMIM: 609025,612318) keratin, type II c ( 551) 725 78.8 3.9e-14
NP_000415 (OMIM: 131760,131800,131900,131960,14804 ( 590) 708 77.3 1.2e-13
XP_016874785 (OMIM: 158000,601928) PREDICTED: kera ( 486) 703 76.8 1.4e-13
NP_001307127 (OMIM: 158000,601928) keratin, type I ( 486) 703 76.8 1.4e-13
NP_775109 (OMIM: 612315,615735) keratin, type II c ( 564) 704 76.9 1.4e-13
XP_005268923 (OMIM: 158000,601928) PREDICTED: kera ( 563) 703 76.8 1.5e-13
NP_002273 (OMIM: 158000,602765) keratin, type II c ( 493) 701 76.6 1.6e-13
NP_005546 (OMIM: 148042,615728) keratin, type II c ( 564) 700 76.6 1.8e-13
NP_476429 (OMIM: 122100,148043) keratin, type II c ( 628) 700 76.6 2e-13
NP_149034 (OMIM: 602766) keratin, type II cuticula ( 600) 696 76.3 2.5e-13
XP_011536637 (OMIM: 602766) PREDICTED: keratin, ty ( 600) 696 76.3 2.5e-13
NP_002272 (OMIM: 158000,602153) keratin, type II c ( 505) 692 75.8 2.8e-13
NP_000413 (OMIM: 148069,167210,184500) keratin, ty ( 432) 689 75.5 3e-13
NP_056932 (OMIM: 616671) keratin, type II cytoskel ( 638) 691 75.8 3.5e-13
NP_005545 (OMIM: 148041,615726) keratin, type II c ( 564) 688 75.5 3.8e-13
NP_000517 (OMIM: 125595,131760,131800,131900,14806 ( 472) 686 75.3 3.8e-13
NP_002274 (OMIM: 602032,602767) keratin, type II c ( 507) 685 75.2 4.3e-13
NP_000414 (OMIM: 146800,600194) keratin, type II c ( 639) 687 75.5 4.4e-13
NP_149022 (OMIM: 601078) keratin, type II cuticula ( 513) 681 74.9 5.5e-13
NP_002263 (OMIM: 123940,193900) keratin, type II c ( 520) 676 74.4 7.5e-13
NP_006112 (OMIM: 113800,139350,144200,146590,60096 ( 644) 677 74.6 8.2e-13
XP_016874238 (OMIM: 608245,615896) PREDICTED: kera ( 441) 667 73.6 1.2e-12
NP_778238 (OMIM: 608247) keratin, type II cytoskel ( 540) 669 73.8 1.2e-12
NP_705694 (OMIM: 148065,615785) keratin, type I cy ( 458) 666 73.5 1.3e-12
NP_258259 (OMIM: 608245,615896) keratin, type II c ( 523) 667 73.6 1.3e-12
NP_002266 (OMIM: 148030) keratin, type I cytoskele ( 456) 663 73.2 1.5e-12
NP_002265 (OMIM: 148065,615785) keratin, type I cy ( 420) 656 72.6 2.2e-12
NP_005548 (OMIM: 148067,167200,613000) keratin, ty ( 473) 657 72.7 2.3e-12
NP_778223 (OMIM: 194300,608248,613981,614929) kera ( 529) 658 72.9 2.3e-12
NP_787028 (OMIM: 611160) keratin, type II cytoskel ( 535) 654 72.5 2.9e-12
NP_778253 (OMIM: 611158) keratin, type II cytoskel ( 578) 651 72.3 3.7e-12
>>NP_002046 (OMIM: 137780,203450) glial fibrillary acidi (432 aa)
initn: 2701 init1: 2701 opt: 2701 Z-score: 1316.5 bits: 252.7 E(85289): 1.4e-66
Smith-Waterman score: 2701; 100.0% identity (100.0% similar) in 432 aa overlap (1-432:1-432)
10 20 30 40 50 60
pF1KB8 MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 QYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 IEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEV
370 380 390 400 410 420
430
pF1KB8 IKESKQEHKDVM
::::::::::::
NP_002 IKESKQEHKDVM
430
>>NP_001124491 (OMIM: 137780,203450) glial fibrillary ac (431 aa)
initn: 2442 init1: 2442 opt: 2450 Z-score: 1197.0 bits: 230.6 E(85289): 6.2e-60
Smith-Waterman score: 2450; 92.4% identity (97.2% similar) in 423 aa overlap (1-421:1-423)
10 20 30 40 50 60
pF1KB8 MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 QYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALD
310 320 330 340 350 360
370 380 390 400 410
pF1KB8 IEIATYRKLLEGEENRITIPVQTFSNLQIR--ETSLDTKSVSEGHLKRNIVVKTVEMRDG
:::::::::::::::::::::::::::::: ... : .. . . ........ ..
NP_001 IEIATYRKLLEGEENRITIPVQTFSNLQIRGGKSTKDGENHKVTRYLKSLTIRVIPIQAH
370 380 390 400 410 420
420 430
pF1KB8 EVIKESKQEHKDVM
...
NP_001 QIVNGTPPARG
430
>>XP_016879940 (OMIM: 137780,203450) PREDICTED: glial fi (472 aa)
initn: 2442 init1: 2442 opt: 2450 Z-score: 1196.5 bits: 230.6 E(85289): 6.6e-60
Smith-Waterman score: 2556; 91.4% identity (91.4% similar) in 464 aa overlap (1-424:1-464)
10 20 30 40 50 60
pF1KB8 MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 QYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALD
310 320 330 340 350 360
370 380 390
pF1KB8 IEIATYRKLLEGEENRITIPVQTFSNLQIR------------------------------
::::::::::::::::::::::::::::::
XP_016 IEIATYRKLLEGEENRITIPVQTFSNLQIRGGKSTKDGENHKVTRYLKSLTIRVIPIQAH
370 380 390 400 410 420
400 410 420 430
pF1KB8 ----------ETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
::::::::::::::::::::::::::::::::::
XP_016 QIVNGTPPARETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
430 440 450 460 470
>>NP_001229305 (OMIM: 137780,203450) glial fibrillary ac (438 aa)
initn: 2442 init1: 2442 opt: 2447 Z-score: 1195.5 bits: 230.3 E(85289): 7.5e-60
Smith-Waterman score: 2447; 97.5% identity (98.5% similar) in 403 aa overlap (1-403:1-401)
10 20 30 40 50 60
pF1KB8 MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDVAKPDLTAALKEIRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 QYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 IEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEV
:::::::::::::::::::::::::::::: . ... :::
NP_001 IEIATYRKLLEGEENRITIPVQTFSNLQIR--GQYSRASWEGHWSPAPSSRACRLLQTGT
370 380 390 400 410
430
pF1KB8 IKESKQEHKDVM
NP_001 EDQGKGIQLSLGAFVTLQRS
420 430
>>XP_006717563 (OMIM: 116300,193060) PREDICTED: vimentin (466 aa)
initn: 1693 init1: 1598 opt: 1608 Z-score: 795.8 bits: 156.5 E(85289): 1.4e-37
Smith-Waterman score: 1608; 58.1% identity (85.9% similar) in 427 aa overlap (8-431:47-465)
10 20 30
pF1KB8 MERRRITSAARRSYVSSGEMMVGGLAPGRRLG---PG
:..: :.:: . . . . :: ::
XP_006 GPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGVYATRSSAVRLRSSVPG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB8 TRLSLARMPPPLPTRVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQN
.:: : :::::: :.:. ::.::..:..:..:::::::.::.:::::::::
XP_006 VRL--------LQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQN
80 90 100 110 120
100 110 120 130 140 150
pF1KB8 KALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANSARLEVERDNLAQDLATVRQK
: : :::.::... ..:.:.:. :.:::: ..:::: ..::.::::::::.:. .:.:
XP_006 KILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB8 LQDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQ
::.: : ::::.: ..::..:.:.:::::::::.:::.::: ::.:.::::..::: :
XP_006 LQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQ
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB8 LARQQVHVELDVAKPDLTAALKEIRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAEL
. .:.:....::.::::::::...: :::..:..:..::::::.::::::..:: :: .
XP_006 IQEQHVQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB8 LRQAKHEANDYRRQLQSLTCDLESLRGTNESLERQMREQEERHVREAASYQEALARLEEE
:::::.:...::::.:::::....:.::::::::::::.:: . :::.::....::..:
XP_006 LRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB8 GQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSL
:..:.::::::.:::::::::.:::::::::::::::::.::..:. .::.:..:::.:
XP_006 IQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLNLRETNL
370 380 390 400 410 420
400 410 420 430
pF1KB8 DTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
:. . . : ::....:::: :::.::.:..:.: :.
XP_006 DSLPLVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE
430 440 450 460
>>NP_003371 (OMIM: 116300,193060) vimentin [Homo sapiens (466 aa)
initn: 1693 init1: 1598 opt: 1608 Z-score: 795.8 bits: 156.5 E(85289): 1.4e-37
Smith-Waterman score: 1608; 58.1% identity (85.9% similar) in 427 aa overlap (8-431:47-465)
10 20 30
pF1KB8 MERRRITSAARRSYVSSGEMMVGGLAPGRRLG---PG
:..: :.:: . . . . :: ::
NP_003 GPGTASRPSSSRSYVTTSTRTYSLGSALRPSTSRSLYASSPGGVYATRSSAVRLRSSVPG
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB8 TRLSLARMPPPLPTRVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQN
.:: : :::::: :.:. ::.::..:..:..:::::::.::.:::::::::
NP_003 VRL--------LQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQN
80 90 100 110 120
100 110 120 130 140 150
pF1KB8 KALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANSARLEVERDNLAQDLATVRQK
: : :::.::... ..:.:.:. :.:::: ..:::: ..::.::::::::.:. .:.:
NP_003 KILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB8 LQDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQ
::.: : ::::.: ..::..:.:.:::::::::.:::.::: ::.:.::::..::: :
NP_003 LQEEMLQREEAENTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHEEEIQELQAQ
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB8 LARQQVHVELDVAKPDLTAALKEIRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAEL
. .:.:....::.::::::::...: :::..:..:..::::::.::::::..:: :: .
NP_003 IQEQHVQIDVDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB8 LRQAKHEANDYRRQLQSLTCDLESLRGTNESLERQMREQEERHVREAASYQEALARLEEE
:::::.:...::::.:::::....:.::::::::::::.:: . :::.::....::..:
NP_003 LRQAKQESTEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAVEAANYQDTIGRLQDE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB8 GQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSL
:..:.::::::.:::::::::.:::::::::::::::::.::..:. .::.:..:::.:
NP_003 IQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLNLRETNL
370 380 390 400 410 420
400 410 420 430
pF1KB8 DTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
:. . . : ::....:::: :::.::.:..:.: :.
NP_003 DSLPLVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE
430 440 450 460
>>NP_001918 (OMIM: 125660,181400,601419,602067,604765,61 (470 aa)
initn: 1559 init1: 1455 opt: 1580 Z-score: 782.5 bits: 154.0 E(85289): 7.6e-37
Smith-Waterman score: 1580; 58.0% identity (84.1% similar) in 429 aa overlap (7-432:47-470)
10 20 30
pF1KB8 MERRRITSAARRSY-VSSGEMMVGGLAPGRRLGPGT
.:.. : : :: .:::. : ..
NP_001 TFGGAPGFPLGSPLSSPVFPRAGFGSKGSSSSVTSRVYQVSRTSGGAGGLGSLR----AS
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB8 RLSLARMPPPLPTR--VDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQ
::. .: : . .::::: :.: : ::..:..:..:::::::.:::::::::::
NP_001 RLGTTRTPSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQ
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB8 NKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANSARLEVERDNLAQDLATVRQ
: :::::.:.:...:::..:..:. :::::: ... :: . ::..:::::: .:: ..
NP_001 NAALAAEVNRLKGREPTRVAELYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKA
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB8 KLQDETNLRLEAENNLAAYRQEADEATLARLDLERKIESLEEEIRFLRKIHEEEVRELQE
:::.: .:. ::::::::.: ..: :::::.::::.::::.::: ::.:.::::.::::
NP_001 KLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQA
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB8 QLARQQVHVELDVAKPDLTAALKEIRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAE
:: .:::.::.:..::::::::..::.:::..:..:. ::::::.:: .:::.:: .: .
NP_001 QLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNND
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB8 LLRQAKHEANDYRRQLQSLTCDLESLRGTNESLERQMREQEERHVREAASYQEALARLEE
:::::.: .::.:.:: ::....:.:::.:: ::::: :.: . ::..::. .:::::
NP_001 ALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEE
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB8 EGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETS
: . :::::::::.:::::::::.:::.:::::::::::::.::..:.::.: :..::::
NP_001 EIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQTYSALNFRETS
380 390 400 410 420 430
400 410 420 430
pF1KB8 LDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
. .. :: : :.....::.: :::::..:. :....:.
NP_001 PEQRG-SEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL
440 450 460 470
>>NP_006253 (OMIM: 105400,170710) peripherin [Homo sapie (470 aa)
initn: 1497 init1: 823 opt: 1438 Z-score: 714.9 bits: 141.5 E(85289): 4.4e-33
Smith-Waterman score: 1438; 56.2% identity (85.1% similar) in 402 aa overlap (30-429:64-459)
10 20 30 40 50
pF1KB8 MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALN
: : : .: :.: :.:::.: :::
NP_006 YSSSSRFSSSRLLGSASPSSSVRLGSFRSPRAGAG---ALLRLPS---ERLDFSMAEALN
40 50 60 70 80
60 70 80 90 100 110
pF1KB8 AGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAE
: ::..:. :..:::::::..::::::::::: :: .::.: :..::.. .. : :
NP_006 QEFLATRSNEKQELQELNDRFANFIEKVRFLEQQNAALRGELSQARGQEPARADQLCQQE
90 100 110 120 130 140
120 130 140 150 160 170
pF1KB8 LRELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEA
::::: .:. : . :..::::.::.:::...:.:..:: : .::.::. .:...:.:
NP_006 LRELRRELELLGRERDRVQVERDGLAEDLAALKQRLEEETRKREDAEHNLVLFRKDVDDA
150 160 170 180 190 200
180 190 200 210 220 230
pF1KB8 TLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVH-VELDVA-KPDLTAALKE
::.::.:::::::: .::.::.:.::::.:.:: .. :::. ::.... ::.:::::..
NP_006 TLSRLELERKIESLMDEIEFLKKLHEEELRDLQVSVESQQVQQVEVEATVKPELTAALRD
210 220 230 240 250 260
240 250 260 270 280 290
pF1KB8 IRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLE
::.:::..:..:..::::::.::.:::.::: :: : :::::.: :. :::.:::::...
NP_006 IRAQYESIAAKNLQEAEEWYKSKYADLSDAANRNHEALRQAKQEMNESRRQIQSLTCEVD
270 280 290 300 310 320
300 310 320 330 340 350
pF1KB8 SLRGTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKL
.::::::.: ::.:: ::. . ::..:: . :::::: ..::.::::::.:::.:::::.
NP_006 GLRGTNEALLRQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLREYQELLNVKM
330 340 350 360 370 380
360 370 380 390 400 410
pF1KB8 ALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRD
:::::::::::::::::.::..::..:..:.:. : ... ...: ......::.: :.
NP_006 ALDIEIATYRKLLEGEESRISVPVHSFASLNIKTTVPEVEPPQDSHSRKTVLIKTIETRN
390 400 410 420 430 440
420 430
pF1KB8 GEVIKESKQEHKDVM
:::. ::..:..
NP_006 GEVVTESQKEQRSELDKSSAHSY
450 460 470
>>XP_005269082 (OMIM: 105400,170710) PREDICTED: peripher (471 aa)
initn: 1465 init1: 791 opt: 1426 Z-score: 709.2 bits: 140.4 E(85289): 9.2e-33
Smith-Waterman score: 1426; 56.1% identity (84.9% similar) in 403 aa overlap (30-429:64-460)
10 20 30 40 50
pF1KB8 MERRRITSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALN
: : : .: :.: :.:::.: :::
XP_005 YSSSSRFSSSRLLGSASPSSSVRLGSFRSPRAGAG---ALLRLPS---ERLDFSMAEALN
40 50 60 70 80
60 70 80 90 100 110
pF1KB8 AGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAE
: ::..:. :..:::::::..::::::::::: :: .::.: :..::.. .. : :
XP_005 QEFLATRSNEKQELQELNDRFANFIEKVRFLEQQNAALRGELSQARGQEPARADQLCQQE
90 100 110 120 130 140
120 130 140 150 160 170
pF1KB8 LRELRLRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEA
::::: .:. : . :..::::.::.:::...:.:..:: : .::.::. .:...:.:
XP_005 LRELRRELELLGRERDRVQVERDGLAEDLAALKQRLEEETRKREDAEHNLVLFRKDVDDA
150 160 170 180 190 200
180 190 200 210 220 230
pF1KB8 TLARLDLERKIESLEEEIRFLRKIHEEEVRELQEQLARQQVH-VELDVA-KPDLTAALKE
::.::.:::::::: .::.::.:.::::.:.:: .. :::. ::.... ::.:::::..
XP_005 TLSRLELERKIESLMDEIEFLKKLHEEELRDLQVSVESQQVQQVEVEATVKPELTAALRD
210 220 230 240 250 260
240 250 260 270 280 290
pF1KB8 IRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLE
::.:::..:..:..::::::.::.:::.::: :: : :::::.: :. :::.:::::...
XP_005 IRAQYESIAAKNLQEAEEWYKSKYADLSDAANRNHEALRQAKQEMNESRRQIQSLTCEVD
270 280 290 300 310 320
300 310 320 330 340 350
pF1KB8 SLRGTNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKL
.::::::.: ::.:: ::. . ::..:: . :::::: ..::.::::::.:::.:::::.
XP_005 GLRGTNEALLRQLRELEEQFALEAGGYQAGAARLEEELRQLKEEMARHLREYQELLNVKM
330 340 350 360 370 380
360 370 380 390 400 410
pF1KB8 ALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRD
:::::::::::::::::.::..::..:..:.:. : ... ...: ......::.: :.
XP_005 ALDIEIATYRKLLEGEESRISVPVHSFASLNIKTTVPEVEPPQDSHSRKTVLIKTIETRN
390 400 410 420 430 440
420 430
pF1KB8 GE-VIKESKQEHKDVM
:: :. ::..:..
XP_005 GEQVVTESQKEQRSELDKSSAHSY
450 460 470
>>NP_116116 (OMIM: 605338) alpha-internexin [Homo sapien (499 aa)
initn: 1108 init1: 631 opt: 1097 Z-score: 552.3 bits: 111.5 E(85289): 5.1e-24
Smith-Waterman score: 1097; 50.3% identity (79.8% similar) in 356 aa overlap (37-387:62-417)
10 20 30 40 50 60
pF1KB8 TSAARRSYVSSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNAGFKETR
:.:: :: .:.: :.: . .: :
NP_116 AGGAGGFRSQSLSRSNVASSAACSSASSLGLGLAYRRPPASDGLDLSQAAARTNEYKIIR
40 50 60 70 80 90
70 80 90 100 110 120
pF1KB8 ASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAK--EPTKLADVYQAELRELR
..:. ... :::::: .::::. :: ::.:: ::: :: . ::.......: :::.::
NP_116 TNEKEQLQGLNDRFAVFIEKVHQLETQNRALEAELAALRQRHAEPSRVGELFQRELRDLR
100 110 120 130 140 150
130 140 150 160 170 180
pF1KB8 LRLDQLTANSARLEVERDNLAQDLATVRQKLQDETNLRLEAENNLAAYRQEADEATLARL
.:.. .. .. .:::.::... .: . ..:. : :: : : ....: ::::::
NP_116 AQLEEASSARSQALLERDGLAEEVQRLRARCEEESRGREGAERALKAQQRDVDGATLARL
160 170 180 190 200 210
190 200 210 220 230 240
pF1KB8 DLERKIESLEEEIRFLRKIHEEEVRELQEQL-ARQQVHVELDV--AKPDLTAALKEIRTQ
:::.:.::: .:. :.:..:.::: :: : : .:. .:.:: ::::::.::.:::.:
NP_116 DLEKKVESLLDELAFVRQVHDEEVAELLATLQASSQAAAEVDVTVAKPDLTSALREIRAQ
220 230 240 250 260 270
250 260 270 280 290 300
pF1KB8 YEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLRG
::..:..:.. :::::.::::.:.. :::..: .: ...: ..::::::. : ..:.:::
NP_116 YESLAAKNLQSAEEWYKSKFANLNEQAARSTEAIRASREEIHEYRRQLQARTIEIEGLRG
280 290 300 310 320 330
310 320 330 340 350 360
pF1KB8 TNESLERQMREQEERHVREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDI
.:::::::. : :::: :.:.::.....::.. .. :.::::::.:::::::::.::::
NP_116 ANESLERQILELEERHSAEVAGYQDSIGQLENDLRNTKSEMARHLREYQDLLNVKMALDI
340 350 360 370 380 390
370 380 390 400 410 420
pF1KB8 EIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVI
:::.:::::::::.:.. ..:.:
NP_116 EIAAYRKLLEGEETRFSTSGLSISGLNPLPNPSYLLPPRILSATTSKVSSTGLSLKKEEE
400 410 420 430 440 450
432 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:41:07 2016 done: Fri Nov 4 10:41:09 2016
Total Scan time: 9.280 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]