FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8213, 154 aa
  1>>>pF1KB8213 154 - 154 aa - 154 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4372+/-0.000297; mu= 10.8366+/- 0.018
 mean_var=60.0858+/-11.703, 0's: 0 Z-trim(116.7): 9  B-trim: 123 in 1/52
 Lambda= 0.165458
 statistics sampled from 28059 (28064) to 28059 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.329), width:  16
 Scan time:  4.370

The best scores are:                                      opt bits E(85289)
NP_000445 (OMIM: 105400,147450) superoxide dismuta ( 154) 1048 258.0 4.3e-69
NP_005116 (OMIM: 603864) copper chaperone for supe ( 274)  484 123.5 2.5e-28
NP_003093 (OMIM: 185490) extracellular superoxide  ( 240)  355 92.7 4.1e-19


>>NP_000445 (OMIM: 105400,147450) superoxide dismutase [  (154 aa)
 initn: 1048 init1: 1048 opt: 1048  Z-score: 1361.4  bits: 258.0 E(85289): 4.3e-69
Smith-Waterman score: 1048; 100.0% identity (100.0% similar) in 154 aa overlap (1-154:1-154)

               10        20        30        40        50        60
pF1KB8 MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 AGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVV
               70        80        90       100       110       120

              130       140       150    
pF1KB8 HEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
       ::::::::::::::::::::::::::::::::::
NP_000 HEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
              130       140       150    

>>NP_005116 (OMIM: 603864) copper chaperone for superoxi  (274 aa)
 initn: 497 init1: 298 opt: 484  Z-score: 629.7  bits: 123.5 E(85289): 2.5e-28
Smith-Waterman score: 484; 50.7% identity (69.9% similar) in 146 aa overlap (5-150:89-230)

                                         10        20        30    
pF1KB8                           MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWG
                                     :: .: : : :::.. : :   .  . . :
NP_005 SQEVQALLEGTGRQAVLKGMGSGQLQNLGAAVAILGGPGTVQGVVRFLQLTPERCL-IEG
       60        70        80        90       100       110        

           40        50        60        70        80        90    
pF1KB8 SIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDG
       .: ::  ::::.:::..:: : .:.: : :::: . .::::.: .:: :::::: :: ::
NP_005 TIDGLEPGLHGLHVHQYGDLTNNCNSCGNHFNPDGASHGGPQDSDRHRGDLGNVRADADG
       120       130       140       150       160       170       

          100       110       120       130       140       150    
pF1KB8 VADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
        :   .::  ...  :  .:::.:.. :  ::::.::.  :  :::.: :::::.:    
NP_005 RAIFRMEDEQLKV-WD--VIGRSLIIDEGEDDLGRGGHPLSKITGNSGERLACGIIARSA
       180       190          200       210       220       230    

NP_005 GLFQNPKQICSCDGLTIWEERGRPIAGKGRKESAQPPAHL
          240       250       260       270    

>>NP_003093 (OMIM: 185490) extracellular superoxide dism  (240 aa)
 initn: 366 init1: 205 opt: 355  Z-score: 464.2  bits: 92.7 E(85289): 4.1e-19
Smith-Waterman score: 355; 42.3% identity (66.9% similar) in 142 aa overlap (15-152:78-212)

                               10        20        30         40   
pF1KB8                 MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGL-TE--
                                     : :.. :.:    . . .. ...:. ::  
NP_003 EVMQRRDDDGALHAACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPN
        50        60        70        80        90       100       

               50        60        70        80        90       100
pF1KB8 -GLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSI
        . ...:::.::: . :: :.:::.:::.  :  :.    : ::.::  : .::      
NP_003 SSSRAIHVHQFGDLSQGCESTGPHYNPLAVPH--PQ----HPGDFGNF-AVRDGSLWRYR
       110       120       130         140            150       160

              110       120       130       140       150          
pF1KB8 EDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ      
          . ::.: : :.::..:::   ::::.:::. :...:::: :::: :.:.        
NP_003 AGLAASLAGPHSIVGRAVVVHAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWER
              170       180       190       200       210       220

NP_003 QAREHSERKKRRRESECKAA
              230       240




154 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 10:37:49 2016 done: Fri Nov  4 10:37:50 2016
 Total Scan time:  4.370 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]