Result of FASTA (omim) for
pF1KB8201
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8201, 203 aa
1>>>pF1KB8201 203 - 203 aa - 203 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1917+/-0.000424; mu= 14.9726+/- 0.027
mean_var=97.5693+/-19.185, 0's: 0 Z-trim(113.2): 456 B-trim: 0 in 0/54
Lambda= 0.129843
statistics sampled from 21910 (22437) to 21910 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.263), width: 16
Scan time: 4.140
The best scores are: opt bits E(85289)
NP_002861 (OMIM: 602672) ras-related protein Rab-1 ( 203) 1320 257.4 1.2e-68
NP_057614 (OMIM: 613532) ras-related protein Rab-8 ( 207) 880 175.0 7.6e-44
NP_005361 (OMIM: 165040) ras-related protein Rab-8 ( 207) 857 170.7 1.5e-42
XP_011526322 (OMIM: 165040) PREDICTED: ras-related ( 215) 841 167.7 1.2e-41
NP_057215 (OMIM: 612672) ras-related protein Rab-1 ( 200) 819 163.5 2.1e-40
XP_016857448 (OMIM: 602672) PREDICTED: ras-related ( 122) 795 158.8 3.3e-39
NP_001258967 (OMIM: 602672) ras-related protein Ra ( 122) 795 158.8 3.3e-39
NP_004152 (OMIM: 179508) ras-related protein Rab-1 ( 205) 713 143.7 2e-34
NP_112243 (OMIM: 612565) ras-related protein Rab-1 ( 201) 704 142.0 6.3e-34
NP_006852 (OMIM: 604199) ras-related protein Rab-3 ( 201) 654 132.6 4.2e-31
NP_055168 (OMIM: 605455) ras-related protein Rab-2 ( 256) 625 127.3 2.1e-29
NP_001304844 (OMIM: 612829) ras-related protein Ra ( 225) 615 125.4 7.1e-29
NP_612462 (OMIM: 612829) ras-related protein Rab-3 ( 227) 615 125.4 7.1e-29
NP_002857 (OMIM: 179490) ras-related protein Rab-3 ( 220) 611 124.6 1.2e-28
XP_011526466 (OMIM: 179490) PREDICTED: ras-related ( 220) 611 124.6 1.2e-28
NP_004274 (OMIM: 604350) ras-related protein Rab-3 ( 219) 607 123.9 2e-28
NP_001006639 (OMIM: 609956) ras-related protein Ra ( 223) 606 123.7 2.3e-28
NP_002858 (OMIM: 179510) ras-related protein Rab-3 ( 219) 604 123.3 2.9e-28
XP_016857447 (OMIM: 179510) PREDICTED: ras-related ( 219) 604 123.3 2.9e-28
NP_001294982 (OMIM: 605455) ras-related protein Ra ( 190) 600 122.5 4.4e-28
NP_001317400 (OMIM: 609956) ras-related protein Ra ( 196) 597 121.9 6.7e-28
NP_001157461 (OMIM: 609956) ras-related protein Ra ( 228) 597 122.0 7.4e-28
XP_016873867 (OMIM: 612565) PREDICTED: ras-related ( 237) 597 122.0 7.6e-28
NP_116235 (OMIM: 607466) ras-related protein Rab-2 ( 216) 593 121.2 1.2e-27
NP_002856 (OMIM: 179509) ras-related protein Rab-2 ( 212) 592 121.0 1.3e-27
NP_001020471 (OMIM: 616448) ras-related protein Ra ( 244) 588 120.4 2.5e-27
NP_783865 (OMIM: 609956) ras-related protein Rab-3 ( 216) 571 117.1 2.1e-26
NP_741995 (OMIM: 300774) ras-related protein Rab-3 ( 213) 567 116.4 3.5e-26
NP_004654 (OMIM: 605570) ras-related protein Rab-1 ( 216) 557 114.5 1.3e-25
NP_004209 (OMIM: 604198) ras-related protein Rab-1 ( 218) 555 114.1 1.7e-25
NP_057238 (OMIM: 612945) ras-related protein Rab-4 ( 213) 543 111.9 7.8e-25
NP_001272990 (OMIM: 605693) ras-related protein Ra ( 203) 542 111.6 8.6e-25
NP_001272989 (OMIM: 605693) ras-related protein Ra ( 203) 542 111.6 8.6e-25
NP_055303 (OMIM: 605693) ras-related protein Rab-3 ( 203) 542 111.6 8.6e-25
NP_001272988 (OMIM: 605693) ras-related protein Ra ( 203) 542 111.6 8.6e-25
NP_004569 (OMIM: 179511) ras-related protein Rab-4 ( 218) 541 111.5 1e-24
NP_057406 (OMIM: 612673) ras-related protein Rab-1 ( 215) 527 108.9 6.3e-24
NP_067075 (OMIM: 602207,614222) ras-related protei ( 206) 525 108.5 7.9e-24
NP_001161078 (OMIM: 604199) ras-related protein Ra ( 152) 519 107.2 1.4e-23
XP_011520750 (OMIM: 605455) PREDICTED: ras-related ( 231) 520 107.6 1.6e-23
NP_065120 (OMIM: 612942) ras-related protein Rab-2 ( 213) 501 104.0 1.8e-22
NP_004153 (OMIM: 179512) ras-related protein Rab-5 ( 215) 494 102.7 4.6e-22
XP_011519339 (OMIM: 614178) PREDICTED: EF-hand cal ( 493) 498 103.8 4.8e-22
XP_011519340 (OMIM: 614178) PREDICTED: EF-hand cal ( 493) 498 103.8 4.8e-22
NP_001138430 (OMIM: 614178) EF-hand calcium-bindin ( 731) 498 104.0 6.2e-22
XP_006719084 (OMIM: 614178) PREDICTED: EF-hand cal ( 732) 498 104.0 6.2e-22
XP_011519338 (OMIM: 614178) PREDICTED: EF-hand cal ( 732) 498 104.0 6.2e-22
XP_011519336 (OMIM: 614178) PREDICTED: EF-hand cal ( 732) 498 104.0 6.2e-22
XP_006722363 (OMIM: 616448) PREDICTED: ras-related ( 212) 491 102.1 6.7e-22
NP_001027004 (OMIM: 300405) ras-related protein Ra ( 278) 492 102.4 7.1e-22
>>NP_002861 (OMIM: 602672) ras-related protein Rab-13 is (203 aa)
initn: 1320 init1: 1320 opt: 1320 Z-score: 1353.7 bits: 257.4 E(85289): 1.2e-68
Smith-Waterman score: 1320; 100.0% identity (100.0% similar) in 203 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KB8 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 NKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGN
130 140 150 160 170 180
190 200
pF1KB8 GNKPPSTDLKTCDKKNTNKCSLG
:::::::::::::::::::::::
NP_002 GNKPPSTDLKTCDKKNTNKCSLG
190 200
>>NP_057614 (OMIM: 613532) ras-related protein Rab-8B [H (207 aa)
initn: 872 init1: 872 opt: 880 Z-score: 908.1 bits: 175.0 E(85289): 7.6e-44
Smith-Waterman score: 880; 63.6% identity (88.8% similar) in 206 aa overlap (1-202:1-206)
10 20 30 40 50 60
pF1KB8 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQ
:::.::.:::::::::::::::::..::.:: ::.:.::::::::::::....:::::::
NP_057 MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLG
.:::::::::.:::::::::::::.::::::.::::.::.::...:.:.::. :::..::
NP_057 IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 NKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGN
:::::. ::.:.::...::: ..::.:.::::::: ::.::: .:::::. : . . . .
NP_057 NKCDMNDKRQVSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMNDS
130 140 150 160 170 180
190 200
pF1KB8 GNKPPSTDLKTCDKKNTN----KCSLG
.. . .: .... . .:::
NP_057 NSAGAGGPVKITENRSKKTSFFRCSLL
190 200
>>NP_005361 (OMIM: 165040) ras-related protein Rab-8A [H (207 aa)
initn: 853 init1: 853 opt: 857 Z-score: 884.8 bits: 170.7 E(85289): 1.5e-42
Smith-Waterman score: 857; 62.1% identity (88.3% similar) in 206 aa overlap (1-202:1-206)
10 20 30 40 50 60
pF1KB8 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQ
:::.::.::::::::::::::::...::.:: ::.:.::::::::::::....::.::::
NP_005 MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLG
.:::::::::.:::::::::::::.::::::.::::.::.::...:.:.::: ::...::
NP_005 IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 NKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGN
::::.. ::.:.::...::: ..::.:.:::::...::..:: .::::: : . ::
NP_005 NKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLEGN
130 140 150 160 170 180
190 200
pF1KB8 GNKPPSTDLK-TCDKKNTN---KCSLG
. . . .: : :... . .: :
NP_005 SPQGSNQGVKITPDQQKRSSFFRCVLL
190 200
>>XP_011526322 (OMIM: 165040) PREDICTED: ras-related pro (215 aa)
initn: 840 init1: 840 opt: 841 Z-score: 868.4 bits: 167.7 E(85289): 1.2e-41
Smith-Waterman score: 841; 70.3% identity (95.9% similar) in 172 aa overlap (1-172:1-172)
10 20 30 40 50 60
pF1KB8 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQ
:::.::.::::::::::::::::...::.:: ::.:.::::::::::::....::.::::
XP_011 MAKTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLG
.:::::::::.:::::::::::::.::::::.::::.::.::...:.:.::: ::...::
XP_011 IWDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 NKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGN
::::.. ::.:.::...::: ..::.:.:::::...::..:: .::::: :
XP_011 NKCDVNDKRQVSKERGEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDKKLGQK
130 140 150 160 170 180
190 200
pF1KB8 GNKPPSTDLKTCDKKNTNKCSLG
XP_011 DNMVCKDREPWLGEKLPRSLGQGQGWCLITAGSSS
190 200 210
>>NP_057215 (OMIM: 612672) ras-related protein Rab-10 [H (200 aa)
initn: 833 init1: 812 opt: 819 Z-score: 846.5 bits: 163.5 E(85289): 2.1e-40
Smith-Waterman score: 819; 66.7% identity (91.1% similar) in 180 aa overlap (3-182:4-183)
10 20 30 40 50
pF1KB8 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKL
:.:: ::::::::::::::::...::..: ::.:.::::::::::.::...::::::
NP_057 MAKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 QVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLL
:.:::::::::.::::.::::::::.::::::. ::::::..:...: :.:. :::.::
NP_057 QIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 GNKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSG
::::::. :: : : .....::::::::::::::...:...:: .::.::: :. .. .
NP_057 GNKCDMDDKRVVPKGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPN
130 140 150 160 170 180
180 190 200
pF1KB8 NGNKPPSTDLKTCDKKNTNKCSLG
. :
NP_057 SENVDISSGGGVTGWKSKCC
190 200
>>XP_016857448 (OMIM: 602672) PREDICTED: ras-related pro (122 aa)
initn: 795 init1: 795 opt: 795 Z-score: 824.8 bits: 158.8 E(85289): 3.3e-39
Smith-Waterman score: 795; 100.0% identity (100.0% similar) in 122 aa overlap (82-203:1-122)
60 70 80 90 100 110
pF1KB8 IEGKKIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENAS
::::::::::::::::::::::::::::::
XP_016 MGIILVYDITDEKSFENIQNWMKSIKENAS
10 20 30
120 130 140 150 160 170
pF1KB8 AGVERLLLGNKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGVERLLLGNKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILL
40 50 60 70 80 90
180 190 200
pF1KB8 KSGGRRSGNGNKPPSTDLKTCDKKNTNKCSLG
::::::::::::::::::::::::::::::::
XP_016 KSGGRRSGNGNKPPSTDLKTCDKKNTNKCSLG
100 110 120
>>NP_001258967 (OMIM: 602672) ras-related protein Rab-13 (122 aa)
initn: 795 init1: 795 opt: 795 Z-score: 824.8 bits: 158.8 E(85289): 3.3e-39
Smith-Waterman score: 795; 100.0% identity (100.0% similar) in 122 aa overlap (82-203:1-122)
60 70 80 90 100 110
pF1KB8 IEGKKIKLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENAS
::::::::::::::::::::::::::::::
NP_001 MGIILVYDITDEKSFENIQNWMKSIKENAS
10 20 30
120 130 140 150 160 170
pF1KB8 AGVERLLLGNKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGVERLLLGNKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILL
40 50 60 70 80 90
180 190 200
pF1KB8 KSGGRRSGNGNKPPSTDLKTCDKKNTNKCSLG
::::::::::::::::::::::::::::::::
NP_001 KSGGRRSGNGNKPPSTDLKTCDKKNTNKCSLG
100 110 120
>>NP_004152 (OMIM: 179508) ras-related protein Rab-1A is (205 aa)
initn: 695 init1: 695 opt: 713 Z-score: 739.1 bits: 143.7 E(85289): 2e-34
Smith-Waterman score: 713; 50.7% identity (81.6% similar) in 201 aa overlap (1-200:4-204)
10 20 30 40 50
pF1KB8 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKI
: ::.::::::::::::::.::..:::.:.....::::::.::::::....:: :
NP_004 MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 KLQVWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERL
:::.:::::::::.:::..::::: :::.:::.::..::.:...:.. : . :: .:..:
NP_004 KLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 LLGNKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRR
:.:::::. .:. :. : ..: :: :.:::::.. ::...: ..: .: . :
NP_004 LVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGA
130 140 150 160 170 180
180 190 200
pF1KB8 SGNGNKPPSTDLKTCD-KKNTNKCSLG
...: . .. ... :.. . :
NP_004 TAGGAEKSNVKIQSTPVKQSGGGCC
190 200
>>NP_112243 (OMIM: 612565) ras-related protein Rab-1B [H (201 aa)
initn: 682 init1: 682 opt: 704 Z-score: 730.1 bits: 142.0 E(85289): 6.3e-34
Smith-Waterman score: 704; 54.3% identity (84.2% similar) in 184 aa overlap (1-184:1-184)
10 20 30 40 50 60
pF1KB8 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQ
: ::.::::::::::::::.::..:::.:.....::::::.::::::....:: ::::
NP_112 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLG
.:::::::::.:::..::::: :::.:::.::..:. :...:.. : . :: .:..::.:
NP_112 IWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 NKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGN
:: :. .:. :.. : ..: :: :.:::::.. ::..:: ..: .: . : ...
NP_112 NKSDLTTKKVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKRMGPGAASG
130 140 150 160 170 180
190 200
pF1KB8 GNKPPSTDLKTCDKKNTNKCSLG
:..:
NP_112 GERPNLKIDSTPVKPAGGGCC
190 200
>>NP_006852 (OMIM: 604199) ras-related protein Rab-35 is (201 aa)
initn: 652 init1: 517 opt: 654 Z-score: 679.5 bits: 132.6 E(85289): 4.2e-31
Smith-Waterman score: 654; 48.5% identity (81.2% similar) in 202 aa overlap (1-200:1-200)
10 20 30 40 50 60
pF1KB8 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQ
::. ::::::::.::::::::. :..:::...:...::.:::.:::::::.:.:.:.:::
NP_006 MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VWDTAGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLG
.:::::::::.:::..::::. :.:.:::.:. .:: :.. :.. :..: . : :.:.:
NP_006 IWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCD-DVCRILVG
70 80 90 100 110
130 140 150 160 170 180
pF1KB8 NKCDMEAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGN
:: : .. :. :.: :.: . ::..:::::: ..::.: :. .. ...:.. ..
NP_006 NKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCIT-ELVLRAKKDNLAK
120 130 140 150 160 170
190 200
pF1KB8 GNKPPSTDLK--TCDKKNTNKCSLG
.. ..:. : ..: ..:
NP_006 QQQQQQNDVVKLTKNSKRKKRCC
180 190 200
203 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:30:32 2016 done: Fri Nov 4 10:30:33 2016
Total Scan time: 4.140 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]