FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8121, 320 aa 1>>>pF1KB8121 320 - 320 aa - 320 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7577+/-0.000548; mu= 12.5267+/- 0.035 mean_var=376.6809+/-82.735, 0's: 0 Z-trim(117.1): 199 B-trim: 1684 in 1/52 Lambda= 0.066083 statistics sampled from 28499 (28726) to 28499 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.337), width: 16 Scan time: 6.130 The best scores are: opt bits E(85289) NP_002127 (OMIM: 164017,615424,615426) heterogeneo ( 320) 2211 224.9 1.7e-58 NP_112420 (OMIM: 164017,615424,615426) heterogeneo ( 372) 1823 188.1 2.5e-47 XP_005268883 (OMIM: 164017,615424,615426) PREDICTE ( 372) 1823 188.1 2.5e-47 XP_016874740 (OMIM: 164017,615424,615426) PREDICTE ( 295) 1629 169.4 8.3e-42 NP_001317180 (OMIM: 605372) heterogeneous nuclear ( 331) 1626 169.2 1.1e-41 NP_001317179 (OMIM: 605372) heterogeneous nuclear ( 331) 1626 169.2 1.1e-41 NP_001317177 (OMIM: 605372) heterogeneous nuclear ( 356) 1512 158.4 2.1e-38 NP_001317176 (OMIM: 605372) heterogeneous nuclear ( 356) 1512 158.4 2.1e-38 NP_919223 (OMIM: 605372) heterogeneous nuclear rib ( 378) 1512 158.4 2.1e-38 NP_001317178 (OMIM: 605372) heterogeneous nuclear ( 378) 1512 158.4 2.1e-38 XP_016867598 (OMIM: 600124,615422) PREDICTED: hete ( 341) 1276 135.8 1.2e-31 NP_002128 (OMIM: 600124,615422) heterogeneous nucl ( 341) 1276 135.8 1.2e-31 XP_016867599 (OMIM: 600124,615422) PREDICTED: hete ( 341) 1276 135.8 1.2e-31 XP_005249786 (OMIM: 600124,615422) PREDICTED: hete ( 353) 1276 135.9 1.2e-31 NP_112533 (OMIM: 600124,615422) heterogeneous nucl ( 353) 1276 135.9 1.2e-31 NP_006796 (OMIM: 609409) heterogeneous nuclear rib ( 305) 1021 111.4 2.4e-24 NP_112737 (OMIM: 601324) heterogeneous nuclear rib ( 336) 658 76.9 6.5e-14 NP_112556 (OMIM: 602688) heterogeneous nuclear rib ( 332) 655 76.6 7.9e-14 NP_112738 (OMIM: 601324) heterogeneous nuclear rib ( 355) 651 76.3 1.1e-13 NP_112740 (OMIM: 607137,609115) heterogeneous nucl ( 420) 648 76.1 1.4e-13 NP_004490 (OMIM: 602688) heterogeneous nuclear rib ( 285) 590 70.3 5.4e-12 XP_005257071 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 577 69.2 1.4e-11 XP_005257072 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 577 69.2 1.4e-11 NP_001309179 (OMIM: 607897) RNA-binding protein Mu ( 324) 567 68.2 2.6e-11 NP_001003810 (OMIM: 601324) heterogeneous nuclear ( 287) 564 67.8 3e-11 NP_620412 (OMIM: 607897) RNA-binding protein Musas ( 328) 562 67.7 3.6e-11 NP_002129 (OMIM: 601324) heterogeneous nuclear rib ( 306) 557 67.2 4.9e-11 XP_011536664 (OMIM: 603328) PREDICTED: RNA-binding ( 343) 551 66.7 7.7e-11 NP_001193929 (OMIM: 607137,609115) heterogeneous n ( 363) 550 66.7 8.4e-11 XP_011536665 (OMIM: 603328) PREDICTED: RNA-binding ( 332) 548 66.4 9.2e-11 XP_006719466 (OMIM: 603328) PREDICTED: RNA-binding ( 351) 541 65.8 1.5e-10 XP_011536663 (OMIM: 603328) PREDICTED: RNA-binding ( 362) 541 65.8 1.5e-10 NP_002433 (OMIM: 603328) RNA-binding protein Musas ( 362) 541 65.8 1.5e-10 NP_001309180 (OMIM: 607897) RNA-binding protein Mu ( 255) 535 65.0 1.9e-10 XP_016879637 (OMIM: 607897) PREDICTED: RNA-binding ( 295) 535 65.1 2.1e-10 NP_733839 (OMIM: 607897) RNA-binding protein Musas ( 251) 531 64.6 2.5e-10 XP_011522588 (OMIM: 607897) PREDICTED: RNA-binding ( 242) 301 42.6 0.00098 XP_016879638 (OMIM: 607897) PREDICTED: RNA-binding ( 259) 301 42.7 0.001 XP_016880670 (OMIM: 601574,612237) PREDICTED: TATA ( 323) 301 42.8 0.0011 XP_011523617 (OMIM: 601574,612237) PREDICTED: TATA ( 501) 301 43.2 0.0014 NP_003478 (OMIM: 601574,612237) TATA-binding prote ( 589) 301 43.3 0.0015 NP_631961 (OMIM: 601574,612237) TATA-binding prote ( 592) 301 43.3 0.0015 XP_016882071 (OMIM: 607430) PREDICTED: DAZ-associa ( 327) 293 42.1 0.0019 XP_011526209 (OMIM: 607430) PREDICTED: DAZ-associa ( 548) 294 42.6 0.0023 XP_011526208 (OMIM: 607430) PREDICTED: DAZ-associa ( 549) 294 42.6 0.0023 XP_011526210 (OMIM: 607430) PREDICTED: DAZ-associa ( 521) 293 42.5 0.0024 XP_011526211 (OMIM: 607430) PREDICTED: DAZ-associa ( 521) 293 42.5 0.0024 XP_011526207 (OMIM: 607430) PREDICTED: DAZ-associa ( 549) 293 42.5 0.0024 XP_011526206 (OMIM: 607430) PREDICTED: DAZ-associa ( 550) 293 42.5 0.0024 XP_016879636 (OMIM: 607897) PREDICTED: RNA-binding ( 315) 289 41.7 0.0024 >>NP_002127 (OMIM: 164017,615424,615426) heterogeneous n (320 aa) initn: 2211 init1: 2211 opt: 2211 Z-score: 1171.2 bits: 224.9 E(85289): 1.7e-58 Smith-Waterman score: 2211; 100.0% identity (100.0% similar) in 320 aa overlap (1-320:1-320) 10 20 30 40 50 60 pF1KB8 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPR 250 260 270 280 290 300 310 320 pF1KB8 NQGGYGGSSSSSSYGSGRRF :::::::::::::::::::: NP_002 NQGGYGGSSSSSSYGSGRRF 310 320 >>NP_112420 (OMIM: 164017,615424,615426) heterogeneous n (372 aa) initn: 2277 init1: 1752 opt: 1823 Z-score: 970.7 bits: 188.1 E(85289): 2.5e-47 Smith-Waterman score: 1962; 85.2% identity (85.2% similar) in 352 aa overlap (1-300:1-352) 10 20 30 40 50 60 pF1KB8 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS 190 200 210 220 230 240 250 pF1KB8 GDGYNGFGNDG------------------------------------------------- ::::::::::: NP_112 GDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGG 250 260 270 280 290 300 260 270 280 290 300 pF1KB8 ---SNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGS ::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 GSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGS 310 320 330 340 350 360 310 320 pF1KB8 SSSSSYGSGRRF NP_112 SSSSSYGSGRRF 370 >>XP_005268883 (OMIM: 164017,615424,615426) PREDICTED: h (372 aa) initn: 2277 init1: 1752 opt: 1823 Z-score: 970.7 bits: 188.1 E(85289): 2.5e-47 Smith-Waterman score: 1962; 85.2% identity (85.2% similar) in 352 aa overlap (1-300:1-352) 10 20 30 40 50 60 pF1KB8 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS 190 200 210 220 230 240 250 pF1KB8 GDGYNGFGNDG------------------------------------------------- ::::::::::: XP_005 GDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGG 250 260 270 280 290 300 260 270 280 290 300 pF1KB8 ---SNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGS ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGS 310 320 330 340 350 360 310 320 pF1KB8 SSSSSYGSGRRF XP_005 SSSSSYGSGRRF 370 >>XP_016874740 (OMIM: 164017,615424,615426) PREDICTED: h (295 aa) initn: 1857 init1: 1554 opt: 1629 Z-score: 871.6 bits: 169.4 E(85289): 8.3e-42 Smith-Waterman score: 1960; 92.2% identity (92.2% similar) in 320 aa overlap (1-320:1-295) 10 20 30 40 50 60 pF1KB8 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS :::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRG-------------- 190 200 210 220 250 260 270 280 290 300 pF1KB8 GDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPR ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -----------SNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPR 230 240 250 260 270 310 320 pF1KB8 NQGGYGGSSSSSSYGSGRRF :::::::::::::::::::: XP_016 NQGGYGGSSSSSSYGSGRRF 280 290 >>NP_001317180 (OMIM: 605372) heterogeneous nuclear ribo (331 aa) initn: 1451 init1: 1296 opt: 1626 Z-score: 869.6 bits: 169.2 E(85289): 1.1e-41 Smith-Waterman score: 1629; 76.9% identity (89.5% similar) in 324 aa overlap (3-320:24-331) 10 20 30 pF1KB8 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGT ....:::::::::::::::::::::.::: :::.::: NP_001 MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 LTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPG ::::::::::.::::::::::::. :::::::: :::::::::::::::::::::: .:: NP_001 LTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 AHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSV :::::::::::::::::::..::::::.:::::.::.: :: ::::::::::::::::.: NP_001 AHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB8 DKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSG-SGNFGGGRGGGFGGND-NFG ::::.:::::.:::::::.:::::::: ::.: ::::.: :::: : :::.:::. ::: NP_001 DKIVVQKYHTINGHNCEVKKALSKQEMQSAGS-QRGRGGGSGNFMG-RGGNFGGGGGNFG 190 200 210 220 230 220 230 240 250 260 270 pF1KB8 RGGNFSGRGGFGGSRGG--GGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQS-SNFG :::::.::::.::. :: :.:::. ::::::.:: :.::::.:::::::..:. ::.: NP_001 RGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDG-NYGGGGNYNDFGNYSGQQQSNYG 240 250 260 270 280 290 280 290 300 310 320 pF1KB8 PMKGGNFGGRSSG-PYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF :::::.::::::: ::::: ::....:..::: ::: NP_001 PMKGGSFGGRSSGSPYGGG------------YGSGGGSGGYGS-RRF 300 310 320 330 >>NP_001317179 (OMIM: 605372) heterogeneous nuclear ribo (331 aa) initn: 1451 init1: 1296 opt: 1626 Z-score: 869.6 bits: 169.2 E(85289): 1.1e-41 Smith-Waterman score: 1629; 76.9% identity (89.5% similar) in 324 aa overlap (3-320:24-331) 10 20 30 pF1KB8 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGT ....:::::::::::::::::::::.::: :::.::: NP_001 MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 LTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPG ::::::::::.::::::::::::. :::::::: :::::::::::::::::::::: .:: NP_001 LTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 AHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSV :::::::::::::::::::..::::::.:::::.::.: :: ::::::::::::::::.: NP_001 AHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB8 DKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSG-SGNFGGGRGGGFGGND-NFG ::::.:::::.:::::::.:::::::: ::.: ::::.: :::: : :::.:::. ::: NP_001 DKIVVQKYHTINGHNCEVKKALSKQEMQSAGS-QRGRGGGSGNFMG-RGGNFGGGGGNFG 190 200 210 220 230 220 230 240 250 260 270 pF1KB8 RGGNFSGRGGFGGSRGG--GGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQS-SNFG :::::.::::.::. :: :.:::. ::::::.:: :.::::.:::::::..:. ::.: NP_001 RGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDG-NYGGGGNYNDFGNYSGQQQSNYG 240 250 260 270 280 290 280 290 300 310 320 pF1KB8 PMKGGNFGGRSSG-PYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF :::::.::::::: ::::: ::....:..::: ::: NP_001 PMKGGSFGGRSSGSPYGGG------------YGSGGGSGGYGS-RRF 300 310 320 330 >>NP_001317177 (OMIM: 605372) heterogeneous nuclear ribo (356 aa) initn: 1463 init1: 1288 opt: 1512 Z-score: 810.6 bits: 158.4 E(85289): 2.1e-38 Smith-Waterman score: 1536; 69.9% identity (83.8% similar) in 345 aa overlap (3-317:2-341) 10 20 30 40 50 60 pF1KB8 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV ....:::::::::::::::::::::.::: :::.:::::::::::::.:::::::::: NP_001 MEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFV 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH ::. :::::::: :::::::::::::::::::::: .:::::::::::::::::::::.. NP_001 TYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA ::::::.:::::.::.: :: ::::::::::::::::.:::::.:::::.:::::::.:: NP_001 LRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKA 120 130 140 150 160 170 190 200 210 220 230 pF1KB8 LSKQEMASASSSQRGRSG-SGNFGGGRGGGFGGND-NFGRGGNFSGRGGFGGSRGG--GG :::::: ::.: ::::.: :::: : :::.:::. ::::::::.::::.::. :: :. NP_001 LSKQEMQSAGS-QRGRGGGSGNFMG-RGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGS 180 190 200 210 220 230 240 250 260 270 280 pF1KB8 YGGSGDGYNGFGNDGSNFGGGGSYNDFGNYN-------NQSSNFGP-------MKGGNFG :::. ::::::.::.:.::: .:.. :.:. ::....: .::::: NP_001 YGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFG 240 250 260 270 280 290 290 300 310 320 pF1KB8 GRSSGPYGGGGQY--FAK----------PRNQGGYGGSSSSSSYGSGRRF : : :::::.: :.. : . :..:: ::.: ::.: NP_001 G---GNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSR 300 310 320 330 340 350 NP_001 RF >>NP_001317176 (OMIM: 605372) heterogeneous nuclear ribo (356 aa) initn: 1463 init1: 1288 opt: 1512 Z-score: 810.6 bits: 158.4 E(85289): 2.1e-38 Smith-Waterman score: 1536; 69.9% identity (83.8% similar) in 345 aa overlap (3-317:2-341) 10 20 30 40 50 60 pF1KB8 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV ....:::::::::::::::::::::.::: :::.:::::::::::::.:::::::::: NP_001 MEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFV 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH ::. :::::::: :::::::::::::::::::::: .:::::::::::::::::::::.. NP_001 TYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA ::::::.:::::.::.: :: ::::::::::::::::.:::::.:::::.:::::::.:: NP_001 LRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKA 120 130 140 150 160 170 190 200 210 220 230 pF1KB8 LSKQEMASASSSQRGRSG-SGNFGGGRGGGFGGND-NFGRGGNFSGRGGFGGSRGG--GG :::::: ::.: ::::.: :::: : :::.:::. ::::::::.::::.::. :: :. NP_001 LSKQEMQSAGS-QRGRGGGSGNFMG-RGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGS 180 190 200 210 220 230 240 250 260 270 280 pF1KB8 YGGSGDGYNGFGNDGSNFGGGGSYNDFGNYN-------NQSSNFGP-------MKGGNFG :::. ::::::.::.:.::: .:.. :.:. ::....: .::::: NP_001 YGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFG 240 250 260 270 280 290 290 300 310 320 pF1KB8 GRSSGPYGGGGQY--FAK----------PRNQGGYGGSSSSSSYGSGRRF : : :::::.: :.. : . :..:: ::.: ::.: NP_001 G---GNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGGYGSR 300 310 320 330 340 350 NP_001 RF >>NP_919223 (OMIM: 605372) heterogeneous nuclear ribonuc (378 aa) initn: 1463 init1: 1288 opt: 1512 Z-score: 810.4 bits: 158.4 E(85289): 2.1e-38 Smith-Waterman score: 1536; 69.9% identity (83.8% similar) in 345 aa overlap (3-317:24-363) 10 20 30 pF1KB8 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGT ....:::::::::::::::::::::.::: :::.::: NP_919 MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 LTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPG ::::::::::.::::::::::::. :::::::: :::::::::::::::::::::: .:: NP_919 LTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 AHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSV :::::::::::::::::::..::::::.:::::.::.: :: ::::::::::::::::.: NP_919 AHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB8 DKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSG-SGNFGGGRGGGFGGND-NFG ::::.:::::.:::::::.:::::::: ::.: ::::.: :::: : :::.:::. ::: NP_919 DKIVVQKYHTINGHNCEVKKALSKQEMQSAGS-QRGRGGGSGNFMG-RGGNFGGGGGNFG 190 200 210 220 230 220 230 240 250 260 pF1KB8 RGGNFSGRGGFGGSRGG--GGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYN-------N :::::.::::.::. :: :.:::. ::::::.::.:.::: .:.. :.:. : NP_919 RGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGN 240 250 260 270 280 290 270 280 290 300 pF1KB8 QSSNFGP-------MKGGNFGGRSSGPYGGGGQY--FAK----------PRNQGGYGGSS :....: .:::::: : :::::.: :.. : . :..:: : NP_919 QGGGYGGGGGYDGYNEGGNFGG---GNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRS 300 310 320 330 340 350 310 320 pF1KB8 SSSSYGSGRRF :.: ::.: NP_919 SGSPYGGGYGSGGGSGGYGSRRF 360 370 >>NP_001317178 (OMIM: 605372) heterogeneous nuclear ribo (378 aa) initn: 1463 init1: 1288 opt: 1512 Z-score: 810.4 bits: 158.4 E(85289): 2.1e-38 Smith-Waterman score: 1536; 69.9% identity (83.8% similar) in 345 aa overlap (3-317:24-363) 10 20 30 pF1KB8 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGT ....:::::::::::::::::::::.::: :::.::: NP_001 MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGT 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 LTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPG ::::::::::.::::::::::::. :::::::: :::::::::::::::::::::: .:: NP_001 LTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPG 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 AHLTVKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSV :::::::::::::::::::..::::::.:::::.::.: :: ::::::::::::::::.: NP_001 AHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTV 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB8 DKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSG-SGNFGGGRGGGFGGND-NFG ::::.:::::.:::::::.:::::::: ::.: ::::.: :::: : :::.:::. ::: NP_001 DKIVVQKYHTINGHNCEVKKALSKQEMQSAGS-QRGRGGGSGNFMG-RGGNFGGGGGNFG 190 200 210 220 230 220 230 240 250 260 pF1KB8 RGGNFSGRGGFGGSRGG--GGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYN-------N :::::.::::.::. :: :.:::. ::::::.::.:.::: .:.. :.:. : NP_001 RGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGN 240 250 260 270 280 290 270 280 290 300 pF1KB8 QSSNFGP-------MKGGNFGGRSSGPYGGGGQY--FAK----------PRNQGGYGGSS :....: .:::::: : :::::.: :.. : . :..:: : NP_001 QGGGYGGGGGYDGYNEGGNFGG---GNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRS 300 310 320 330 340 350 310 320 pF1KB8 SSSSYGSGRRF :.: ::.: NP_001 SGSPYGGGYGSGGGSGGYGSRRF 360 370 320 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 09:43:04 2016 done: Fri Nov 4 09:43:06 2016 Total Scan time: 6.130 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]