Result of FASTA (ccds) for pF1KB8108
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8108, 478 aa
  1>>>pF1KB8108 478 - 478 aa - 478 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.8467+/-0.000981; mu= 6.9709+/- 0.059
 mean_var=157.1655+/-31.235, 0's: 0 Z-trim(110.3): 24  B-trim: 0 in 0/50
 Lambda= 0.102305
 statistics sampled from 11490 (11498) to 11490 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.353), width:  16
 Scan time:  2.780

The best scores are:                                      opt bits E(32554)
CCDS9052.1 METAP2 gene_id:10988|Hs108|chr12        ( 478) 3253 492.1 5.5e-139
CCDS81724.1 METAP2 gene_id:10988|Hs108|chr12       ( 477) 3236 489.6 3.1e-138
CCDS81725.1 METAP2 gene_id:10988|Hs108|chr12       ( 455) 2553 388.8 6.6e-108
CCDS81723.1 METAP2 gene_id:10988|Hs108|chr12       ( 455) 2374 362.3  6e-100
CCDS8902.1 PA2G4 gene_id:5036|Hs108|chr12          ( 394)  385 68.7 1.3e-11


>>CCDS9052.1 METAP2 gene_id:10988|Hs108|chr12             (478 aa)
 initn: 3253 init1: 3253 opt: 3253  Z-score: 2608.7  bits: 492.1 E(32554): 5.5e-139
Smith-Waterman score: 3253; 100.0% identity (100.0% similar) in 478 aa overlap (1-478:1-478)

               10        20        30        40        50        60
pF1KB8 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
              370       380       390       400       410       420

              430       440       450       460       470        
pF1KB8 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
              430       440       450       460       470        

>>CCDS81724.1 METAP2 gene_id:10988|Hs108|chr12            (477 aa)
 initn: 3001 init1: 3001 opt: 3236  Z-score: 2595.2  bits: 489.6 E(32554): 3.1e-138
Smith-Waterman score: 3236; 99.8% identity (99.8% similar) in 478 aa overlap (1-478:1-477)

               10        20        30        40        50        60
pF1KB8 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
       :::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
CCDS81 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSA-GEQEPDKES
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KB8 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB8 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KB8 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KB8 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KB8 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
     300       310       320       330       340       350         

              370       380       390       400       410       420
pF1KB8 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
     360       370       380       390       400       410         

              430       440       450       460       470        
pF1KB8 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
     420       430       440       450       460       470       

>>CCDS81725.1 METAP2 gene_id:10988|Hs108|chr12            (455 aa)
 initn: 2904 init1: 2546 opt: 2553  Z-score: 2050.7  bits: 388.8 E(32554): 6.6e-108
Smith-Waterman score: 3020; 95.0% identity (95.0% similar) in 478 aa overlap (1-478:1-455)

               10        20        30        40        50        60
pF1KB8 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
       :::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
CCDS81 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSA-GEQEPDKES
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KB8 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
       ::::::::::::::::::::::::::                       :::::::::::
CCDS81 GASVDEVARQLERSALEDKERDEDDE----------------------AKVQTDPPSVPI
      60        70        80                              90       

              130       140       150       160       170       180
pF1KB8 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
       100       110       120       130       140       150       

              190       200       210       220       230       240
pF1KB8 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
       160       170       180       190       200       210       

              250       260       270       280       290       300
pF1KB8 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
       220       230       240       250       260       270       

              310       320       330       340       350       360
pF1KB8 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
       280       290       300       310       320       330       

              370       380       390       400       410       420
pF1KB8 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
       340       350       360       370       380       390       

              430       440       450       460       470        
pF1KB8 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
       400       410       420       430       440       450     

>>CCDS81723.1 METAP2 gene_id:10988|Hs108|chr12            (455 aa)
 initn: 2374 init1: 2374 opt: 2374  Z-score: 1907.9  bits: 362.3 E(32554): 6e-100
Smith-Waterman score: 3012; 95.0% identity (95.0% similar) in 478 aa overlap (1-478:1-455)

               10        20        30        40        50        60
pF1KB8 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
       ::::::::::::::::::::::::::::::::::::::::::::::::            
CCDS81 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGR-----------
               70        80        90       100                    

              130       140       150       160       170       180
pF1KB8 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
                   ::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 ------------QECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
                 110       120       130       140       150       

              190       200       210       220       230       240
pF1KB8 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
       160       170       180       190       200       210       

              250       260       270       280       290       300
pF1KB8 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
       220       230       240       250       260       270       

              310       320       330       340       350       360
pF1KB8 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
       280       290       300       310       320       330       

              370       380       390       400       410       420
pF1KB8 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
       340       350       360       370       380       390       

              430       440       450       460       470        
pF1KB8 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
       400       410       420       430       440       450     

>>CCDS8902.1 PA2G4 gene_id:5036|Hs108|chr12               (394 aa)
 initn: 141 init1: 108 opt: 385  Z-score: 322.2  bits: 68.7 E(32554): 1.3e-11
Smith-Waterman score: 385; 23.8% identity (59.8% similar) in 336 aa overlap (153-475:5-336)

            130       140       150       160       170       180  
pF1KB8 LYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKY
                                     .:..    : . . . .. ...   .: . 
CCDS89                           MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRS
                                         10        20        30    

            190            200       210       220       230       
pF1KB8 VMSWIKPGMTMIEICEK-----LEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAG
       ..   . :.... .:::     .:. .. . ::. .. :.::::. :.:::. :..:  .
CCDS89 LVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKS
           40        50        60        70        80        90    

       240        250       260       270       280        290     
pF1KB8 DTT-VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVK-DATNTGIKCAGIDV
       :   .:.  :. :::.:.:..: : . : : . .    : . . : :. ...  ::   .
CCDS89 DQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAAL
          100       110       120       130       140       150    

         300       310       320       330       340               
pF1KB8 RLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTV---PI---VKG
       ::   :.   .: :... .. .....  ::... .:.. :. : . ::.   :     : 
CCDS89 RLVKPGNQNTQVTEAWN-KV-AHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKD
          160       170         180       190       200       210  

     350       360       370       380       390       400         
pF1KB8 GEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN
        : ...:  ::::.... :.:.: ..:  . .  .:     .  ...  .. ... ... 
CCDS89 HEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERR
            220       230       240       250       260       270  

     410       420       430       440       450       460         
pF1KB8 FGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCK
       : .. :  : ..   :.:  :.. .     ...:.  : . .: ..:::. :.:: :.  
CCDS89 FDAMPFTLRAFE--DEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGP
            280         290       300       310       320       330

     470                                                           
pF1KB8 EVVSRGDDY                                                   
         .. :                                                      
CCDS89 MRITSGPFEPDLYKSEMEVQDAELKALLQSSASRKTQKKKKKKASKTAENATSGETLEEN
              340       350       360       370       380       390




478 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 09:33:54 2016 done: Fri Nov  4 09:33:55 2016
 Total Scan time:  2.780 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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