Result of FASTA (ccds) for
pF1KB8108
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8108, 478 aa
1>>>pF1KB8108 478 - 478 aa - 478 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8467+/-0.000981; mu= 6.9709+/- 0.059
mean_var=157.1655+/-31.235, 0's: 0 Z-trim(110.3): 24 B-trim: 0 in 0/50
Lambda= 0.102305
statistics sampled from 11490 (11498) to 11490 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.353), width: 16
Scan time: 2.780
The best scores are: opt bits E(32554)
CCDS9052.1 METAP2 gene_id:10988|Hs108|chr12 ( 478) 3253 492.1 5.5e-139
CCDS81724.1 METAP2 gene_id:10988|Hs108|chr12 ( 477) 3236 489.6 3.1e-138
CCDS81725.1 METAP2 gene_id:10988|Hs108|chr12 ( 455) 2553 388.8 6.6e-108
CCDS81723.1 METAP2 gene_id:10988|Hs108|chr12 ( 455) 2374 362.3 6e-100
CCDS8902.1 PA2G4 gene_id:5036|Hs108|chr12 ( 394) 385 68.7 1.3e-11
>>CCDS9052.1 METAP2 gene_id:10988|Hs108|chr12 (478 aa)
initn: 3253 init1: 3253 opt: 3253 Z-score: 2608.7 bits: 492.1 E(32554): 5.5e-139
Smith-Waterman score: 3253; 100.0% identity (100.0% similar) in 478 aa overlap (1-478:1-478)
10 20 30 40 50 60
pF1KB8 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
370 380 390 400 410 420
430 440 450 460 470
pF1KB8 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS90 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
430 440 450 460 470
>>CCDS81724.1 METAP2 gene_id:10988|Hs108|chr12 (477 aa)
initn: 3001 init1: 3001 opt: 3236 Z-score: 2595.2 bits: 489.6 E(32554): 3.1e-138
Smith-Waterman score: 3236; 99.8% identity (99.8% similar) in 478 aa overlap (1-478:1-477)
10 20 30 40 50 60
pF1KB8 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
CCDS81 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSA-GEQEPDKES
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB8 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB8 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB8 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
360 370 380 390 400 410
430 440 450 460 470
pF1KB8 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
420 430 440 450 460 470
>>CCDS81725.1 METAP2 gene_id:10988|Hs108|chr12 (455 aa)
initn: 2904 init1: 2546 opt: 2553 Z-score: 2050.7 bits: 388.8 E(32554): 6.6e-108
Smith-Waterman score: 3020; 95.0% identity (95.0% similar) in 478 aa overlap (1-478:1-455)
10 20 30 40 50 60
pF1KB8 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
CCDS81 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSA-GEQEPDKES
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
:::::::::::::::::::::::::: :::::::::::
CCDS81 GASVDEVARQLERSALEDKERDEDDE----------------------AKVQTDPPSVPI
60 70 80 90
130 140 150 160 170 180
pF1KB8 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB8 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB8 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
340 350 360 370 380 390
430 440 450 460 470
pF1KB8 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
400 410 420 430 440 450
>>CCDS81723.1 METAP2 gene_id:10988|Hs108|chr12 (455 aa)
initn: 2374 init1: 2374 opt: 2374 Z-score: 1907.9 bits: 362.3 E(32554): 6e-100
Smith-Waterman score: 3012; 95.0% identity (95.0% similar) in 478 aa overlap (1-478:1-455)
10 20 30 40 50 60
pF1KB8 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MAGVEEVAASGSHLNGDLDPDDREEGAASTAEEAAKKKRRKKKKSKGPSAAGEQEPDKES
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGPKVQTDPPSVPI
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GASVDEVARQLERSALEDKERDEDDEDGDGDGDGATGKKKKKKKKKRGR-----------
70 80 90 100
130 140 150 160 170 180
pF1KB8 CDLYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 ------------QECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVR
110 120 130 140 150
190 200 210 220 230 240
pF1KB8 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 KYVMSWIKPGMTMIEICEKLEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAGDTT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB8 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVKDATNTGIKCAGIDVRLCDV
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB8 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTVPIVKGGEATRMEEGEV
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB8 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 YAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINENFGTLAFCRRWL
340 350 360 370 380 390
430 440 450 460 470
pF1KB8 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCKEVVSRGDDY
400 410 420 430 440 450
>>CCDS8902.1 PA2G4 gene_id:5036|Hs108|chr12 (394 aa)
initn: 141 init1: 108 opt: 385 Z-score: 322.2 bits: 68.7 E(32554): 1.3e-11
Smith-Waterman score: 385; 23.8% identity (59.8% similar) in 336 aa overlap (153-475:5-336)
130 140 150 160 170 180
pF1KB8 LYPNGVFPKGQECEYPPTQDGRTAAWRTTSEEKKALDQASEEIWNDFREAAEAHRQVRKY
.:.. : . . . .. ... .: .
CCDS89 MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRS
10 20 30
190 200 210 220 230
pF1KB8 VMSWIKPGMTMIEICEK-----LEDCSRKLIKENGLNAGLAFPTGCSLNNCAAHYTPNAG
.. . :.... .::: .:. .. . ::. .. :.::::. :.:::. :..: .
CCDS89 LVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKS
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB8 DTT-VLQYDDICKIDFGTHISGRIIDCAFTVTFNPKYDTLLKAVK-DATNTGIKCAGIDV
: .:. :. :::.:.:..: : . : : . . : . . : :. ... :: .
CCDS89 DQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAAL
100 110 120 130 140 150
300 310 320 330 340
pF1KB8 RLCDVGEAIQEVMESYEVEIDGKTYQVKPIRNLNGHSIGQYRIHAGKTV---PI---VKG
:: :. .: :... .. ..... ::... .:.. :. : . ::. : :
CCDS89 RLVKPGNQNTQVTEAWN-KV-AHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKD
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB8 GEATRMEEGEVYAIETFGSTGKGVVHDDMECSHYMKNFDVGHVPIRLPRTKHLLNVINEN
: ...: ::::.... :.:.: ..: . . .: . ... .. ... ...
CCDS89 HEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERR
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB8 FGTLAFCRRWLDRLGESKYLMALKNLCDLGIVDPYPPLCDIKGSYTAQFEHTILLRPTCK
: .. : : .. :.: :.. . ...:. : . .: ..:::. :.:: :.
CCDS89 FDAMPFTLRAFE--DEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGP
280 290 300 310 320 330
470
pF1KB8 EVVSRGDDY
.. :
CCDS89 MRITSGPFEPDLYKSEMEVQDAELKALLQSSASRKTQKKKKKKASKTAENATSGETLEEN
340 350 360 370 380 390
478 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:33:54 2016 done: Fri Nov 4 09:33:55 2016
Total Scan time: 2.780 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]