Result of FASTA (omim) for
pF1KB8006
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8006, 773 aa
1>>>pF1KB8006 773 - 773 aa - 773 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7124+/-0.000306; mu= 15.9172+/- 0.019
mean_var=132.2176+/-27.403, 0's: 0 Z-trim(120.2): 46 B-trim: 586 in 1/54
Lambda= 0.111540
statistics sampled from 35055 (35130) to 35055 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.75), E-opt: 0.2 (0.412), width: 16
Scan time: 13.650
The best scores are: opt bits E(85289)
NP_073557 (OMIM: 192430,609030) microprocessor com ( 773) 5195 847.5 0
NP_001177255 (OMIM: 192430,609030) microprocessor ( 740) 3640 597.3 7.7e-170
XP_006724331 (OMIM: 192430,609030) PREDICTED: micr ( 416) 2750 453.9 6.5e-127
>>NP_073557 (OMIM: 192430,609030) microprocessor complex (773 aa)
initn: 5195 init1: 5195 opt: 5195 Z-score: 4522.2 bits: 847.5 E(85289): 0
Smith-Waterman score: 5195; 100.0% identity (100.0% similar) in 773 aa overlap (1-773:1-773)
10 20 30 40 50 60
pF1KB8 METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LPAEDPFNFYGASLLSKGSFSKGRLLIDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 LPAEDPFNFYGASLLSKGSFSKGRLLIDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVGDGVGIGGESAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 SVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVGDGVGIGGESAD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 KKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 DDFDNDVDALLEEGLCAPKKRRTEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 DDFDNDVDALLEEGLCAPKKRRTEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 EPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 NEEREQSSDLTPSGDVSPVKPLSRSAELEFPLDEPDSMGADPGPPDEKDPLGAEAAPGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 NEEREQSSDLTPSGDVSPVKPLSRSAELEFPLDEPDSMGADPGPPDEKDPLGAEAAPGAL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 GQVKAKVEVCKDESVDLEEFRSYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 GQVKAKVEVCKDESVDLEEFRSYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESER
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 PILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 PILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 PFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPKDSEELEYFNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 PFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPKDSEELEYFNH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 ISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 ISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKH
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 TVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 TVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQ
670 680 690 700 710 720
730 740 750 760 770
pF1KB8 YAKKNKPNLHILSKLQEEMKRLAEEREETRKKPKMSIVASAQPGGEPLCTVDV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 YAKKNKPNLHILSKLQEEMKRLAEEREETRKKPKMSIVASAQPGGEPLCTVDV
730 740 750 760 770
>>NP_001177255 (OMIM: 192430,609030) microprocessor comp (740 aa)
initn: 4975 init1: 3640 opt: 3640 Z-score: 3170.1 bits: 597.3 E(85289): 7.7e-170
Smith-Waterman score: 4913; 95.7% identity (95.7% similar) in 773 aa overlap (1-773:1-740)
10 20 30 40 50 60
pF1KB8 METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 METDESPSPLPCGPAGEAVMESRARPFQALPREQSPPPPLQTSSGAEVMDVGSGGDGQSE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LPAEDPFNFYGASLLSKGSFSKGRLLIDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPAEDPFNFYGASLLSKGSFSKGRLLIDPNCSGHSPRTARHAPAVRKFSPDLKLLKDVKI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVGDGVGIGGESAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVSFTESCRSKDRKVLYTGAERDVRAECGLLLSPVSGDVHACPFGGSVGDGVGIGGESAD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 KKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKDEENELDQEKRVEYAVLDELEDFTDNLELDEEGAGGFTAKAIVQRDRVDEEALNFPYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 DDFDNDVDALLEEGLCAPKKRRTEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDFDNDVDALLEEGLCAPKKRRTEEKYGGDSDHPSDGETSVQPMMTKIKTVLKSRGRPPT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPLPDGWIMTFHNSGVPVYLHRESRVVTWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 NEEREQSSDLTPSGDVSPVKPLSRSAELEFPLDEPDSMGADPGPPDEKDPLGAEAAPGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEEREQSSDLTPSGDVSPVKPLSRSAELEFPLDEPDSMGADPGPPDEKDPLGAEAAPGAL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 GQVKAKVEVCKDESVDLEEFRSYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQVKAKVEVCKDESVDLEEFRSYLEKRFDFEQVTVKKFRTWAERRQFNREMKRKQAESER
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 PILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFECENPSE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PILPANQKLITLSVQDAPTKKEFVINPNGKSEVCILHEYMQRVLKVRPVYNFFEC-----
490 500 510 520 530
550 560 570 580 590 600
pF1KB8 PFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPKDSEELEYFNH
::::::::::::::::::::::::::::::::
NP_001 ----------------------------ARATLEILIPDFVKQTSEEKPKDSEELEYFNH
540 550 560
610 620 630 640 650 660
pF1KB8 ISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISIEDSRVYELTSKAGLLSPYQILHECLKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKH
570 580 590 600 610 620
670 680 690 700 710 720
pF1KB8 TVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVRGWCKNKRVGKQLASQKILQLLHPHVKNWGSLLRMYGRESSKMVKQETSDKSVIELQQ
630 640 650 660 670 680
730 740 750 760 770
pF1KB8 YAKKNKPNLHILSKLQEEMKRLAEEREETRKKPKMSIVASAQPGGEPLCTVDV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAKKNKPNLHILSKLQEEMKRLAEEREETRKKPKMSIVASAQPGGEPLCTVDV
690 700 710 720 730 740
>>XP_006724331 (OMIM: 192430,609030) PREDICTED: micropro (416 aa)
initn: 2750 init1: 2750 opt: 2750 Z-score: 2399.5 bits: 453.9 E(85289): 6.5e-127
Smith-Waterman score: 2750; 100.0% identity (100.0% similar) in 416 aa overlap (358-773:1-416)
330 340 350 360 370 380
pF1KB8 TWSRPYFLGTGSIRKHDPPLSSIPCLHYKKMKDNEEREQSSDLTPSGDVSPVKPLSRSAE
::::::::::::::::::::::::::::::
XP_006 MKDNEEREQSSDLTPSGDVSPVKPLSRSAE
10 20 30
390 400 410 420 430 440
pF1KB8 LEFPLDEPDSMGADPGPPDEKDPLGAEAAPGALGQVKAKVEVCKDESVDLEEFRSYLEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LEFPLDEPDSMGADPGPPDEKDPLGAEAAPGALGQVKAKVEVCKDESVDLEEFRSYLEKR
40 50 60 70 80 90
450 460 470 480 490 500
pF1KB8 FDFEQVTVKKFRTWAERRQFNREMKRKQAESERPILPANQKLITLSVQDAPTKKEFVINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FDFEQVTVKKFRTWAERRQFNREMKRKQAESERPILPANQKLITLSVQDAPTKKEFVINP
100 110 120 130 140 150
510 520 530 540 550 560
pF1KB8 NGKSEVCILHEYMQRVLKVRPVYNFFECENPSEPFGASVTIDGVTYGSGTASSKKLAKNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NGKSEVCILHEYMQRVLKVRPVYNFFECENPSEPFGASVTIDGVTYGSGTASSKKLAKNK
160 170 180 190 200 210
570 580 590 600 610 620
pF1KB8 AARATLEILIPDFVKQTSEEKPKDSEELEYFNHISIEDSRVYELTSKAGLLSPYQILHEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AARATLEILIPDFVKQTSEEKPKDSEELEYFNHISIEDSRVYELTSKAGLLSPYQILHEC
220 230 240 250 260 270
630 640 650 660 670 680
pF1KB8 LKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKHTVRGWCKNKRVGKQLASQKILQLLHPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKRNHGMGDTSIKFEVVPGKNQKSEYVMACGKHTVRGWCKNKRVGKQLASQKILQLLHPH
280 290 300 310 320 330
690 700 710 720 730 740
pF1KB8 VKNWGSLLRMYGRESSKMVKQETSDKSVIELQQYAKKNKPNLHILSKLQEEMKRLAEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKNWGSLLRMYGRESSKMVKQETSDKSVIELQQYAKKNKPNLHILSKLQEEMKRLAEERE
340 350 360 370 380 390
750 760 770
pF1KB8 ETRKKPKMSIVASAQPGGEPLCTVDV
::::::::::::::::::::::::::
XP_006 ETRKKPKMSIVASAQPGGEPLCTVDV
400 410
773 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:14:09 2016 done: Wed Nov 2 23:14:11 2016
Total Scan time: 13.650 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]