Result of FASTA (omim) for
pF1KB7894
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7894, 656 aa
1>>>pF1KB7894 656 - 656 aa - 656 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4406+/-0.000334; mu= 6.6967+/- 0.021
mean_var=212.3587+/-42.279, 0's: 0 Z-trim(122.1): 165 B-trim: 473 in 1/58
Lambda= 0.088011
statistics sampled from 39594 (39771) to 39594 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.466), width: 16
Scan time: 10.320
The best scores are: opt bits E(85289)
XP_016881207 (OMIM: 609150) PREDICTED: CXXC-type z ( 656) 4677 606.7 8.5e-173
NP_055408 (OMIM: 609150) CXXC-type zinc finger pro ( 656) 4677 606.7 8.5e-173
NP_001095124 (OMIM: 609150) CXXC-type zinc finger ( 660) 4659 604.4 4.2e-172
XP_011524242 (OMIM: 609150) PREDICTED: CXXC-type z ( 660) 4659 604.4 4.2e-172
XP_016881208 (OMIM: 609150) PREDICTED: CXXC-type z ( 531) 3566 465.6 2.1e-130
XP_011524243 (OMIM: 609150) PREDICTED: CXXC-type z ( 535) 3548 463.3 1e-129
NP_001310878 (OMIM: 156535) methyl-CpG-binding dom ( 461) 305 51.4 8.4e-06
XP_011524304 (OMIM: 156535) PREDICTED: methyl-CpG- ( 584) 305 51.5 1e-05
XP_016881253 (OMIM: 156535) PREDICTED: methyl-CpG- ( 584) 305 51.5 1e-05
XP_011524305 (OMIM: 156535) PREDICTED: methyl-CpG- ( 584) 305 51.5 1e-05
XP_016881250 (OMIM: 156535) PREDICTED: methyl-CpG- ( 596) 305 51.5 1e-05
XP_016881248 (OMIM: 156535) PREDICTED: methyl-CpG- ( 615) 305 51.5 1e-05
XP_016881246 (OMIM: 156535) PREDICTED: methyl-CpG- ( 615) 305 51.5 1e-05
XP_016881247 (OMIM: 156535) PREDICTED: methyl-CpG- ( 615) 305 51.5 1e-05
XP_016881245 (OMIM: 156535) PREDICTED: methyl-CpG- ( 616) 305 51.6 1e-05
XP_016881243 (OMIM: 156535) PREDICTED: methyl-CpG- ( 627) 305 51.6 1.1e-05
XP_011524296 (OMIM: 156535) PREDICTED: methyl-CpG- ( 630) 305 51.6 1.1e-05
NP_001191066 (OMIM: 156535) methyl-CpG-binding dom ( 630) 305 51.6 1.1e-05
XP_011524295 (OMIM: 156535) PREDICTED: methyl-CpG- ( 630) 305 51.6 1.1e-05
XP_011524293 (OMIM: 156535) PREDICTED: methyl-CpG- ( 634) 305 51.6 1.1e-05
XP_016881240 (OMIM: 156535) PREDICTED: methyl-CpG- ( 647) 305 51.6 1.1e-05
XP_006722519 (OMIM: 156535) PREDICTED: methyl-CpG- ( 662) 305 51.6 1.1e-05
NP_001310876 (OMIM: 156535) methyl-CpG-binding dom ( 665) 305 51.6 1.1e-05
NP_001310871 (OMIM: 156535) methyl-CpG-binding dom ( 680) 305 51.6 1.1e-05
NP_001191067 (OMIM: 156535) methyl-CpG-binding dom ( 629) 304 51.4 1.2e-05
NP_001310882 (OMIM: 156535) methyl-CpG-binding dom ( 379) 282 48.4 5.5e-05
NP_001191080 (OMIM: 156535) methyl-CpG-binding dom ( 536) 282 48.6 7.1e-05
NP_056670 (OMIM: 156535) methyl-CpG-binding domain ( 586) 282 48.6 7.6e-05
NP_001191071 (OMIM: 156535) methyl-CpG-binding dom ( 550) 272 47.3 0.00018
NP_056723 (OMIM: 156535) methyl-CpG-binding domain ( 556) 272 47.3 0.00018
XP_016881258 (OMIM: 156535) PREDICTED: methyl-CpG- ( 559) 272 47.3 0.00018
XP_011524309 (OMIM: 156535) PREDICTED: methyl-CpG- ( 559) 272 47.3 0.00018
XP_016881266 (OMIM: 156535) PREDICTED: methyl-CpG- ( 571) 272 47.3 0.00018
XP_016881251 (OMIM: 156535) PREDICTED: methyl-CpG- ( 590) 272 47.3 0.00018
NP_001310880 (OMIM: 156535) methyl-CpG-binding dom ( 602) 272 47.4 0.00019
NP_001191068 (OMIM: 156535) methyl-CpG-binding dom ( 605) 272 47.4 0.00019
XP_016881249 (OMIM: 156535) PREDICTED: methyl-CpG- ( 605) 272 47.4 0.00019
XP_005258328 (OMIM: 156535) PREDICTED: methyl-CpG- ( 605) 272 47.4 0.00019
NP_056671 (OMIM: 156535) methyl-CpG-binding domain ( 605) 272 47.4 0.00019
XP_011524301 (OMIM: 156535) PREDICTED: methyl-CpG- ( 609) 272 47.4 0.00019
XP_016881244 (OMIM: 156535) PREDICTED: methyl-CpG- ( 617) 272 47.4 0.00019
XP_016881242 (OMIM: 156535) PREDICTED: methyl-CpG- ( 637) 272 47.4 0.0002
XP_016881241 (OMIM: 156535) PREDICTED: methyl-CpG- ( 640) 272 47.4 0.0002
NP_001191065 (OMIM: 156535) methyl-CpG-binding dom ( 655) 272 47.4 0.0002
NP_001191070 (OMIM: 156535) methyl-CpG-binding dom ( 567) 263 46.2 0.0004
XP_016881252 (OMIM: 156535) PREDICTED: methyl-CpG- ( 589) 263 46.2 0.00041
NP_001310879 (OMIM: 156535) methyl-CpG-binding dom ( 589) 263 46.2 0.00041
XP_011524300 (OMIM: 156535) PREDICTED: methyl-CpG- ( 616) 263 46.2 0.00042
XP_011526806 (OMIM: 604140) PREDICTED: death-induc (2276) 260 46.3 0.0014
XP_011526809 (OMIM: 604140) PREDICTED: death-induc (2276) 260 46.3 0.0014
>>XP_016881207 (OMIM: 609150) PREDICTED: CXXC-type zinc (656 aa)
initn: 4677 init1: 4677 opt: 4677 Z-score: 3223.2 bits: 606.7 E(85289): 8.5e-173
Smith-Waterman score: 4677; 100.0% identity (100.0% similar) in 656 aa overlap (1-656:1-656)
10 20 30 40 50 60
pF1KB7 MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQIKRSARMCGECEACRRTED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQIKRSARMCGECEACRRTED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 CGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKKKEERYKRHRQKQKHKDKWKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKKKEERYKRHRQKQKHKDKWKH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 PERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 IAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGDSDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGDSDDT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 DLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 YCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAE
550 560 570 580 590 600
610 620 630 640 650
pF1KB7 VDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR
610 620 630 640 650
>>NP_055408 (OMIM: 609150) CXXC-type zinc finger protein (656 aa)
initn: 4677 init1: 4677 opt: 4677 Z-score: 3223.2 bits: 606.7 E(85289): 8.5e-173
Smith-Waterman score: 4677; 100.0% identity (100.0% similar) in 656 aa overlap (1-656:1-656)
10 20 30 40 50 60
pF1KB7 MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQIKRSARMCGECEACRRTED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 RAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQIKRSARMCGECEACRRTED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 CGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 CGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKKKEERYKRHRQKQKHKDKWKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKKKEERYKRHRQKQKHKDKWKH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 PERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLAANRIYEILPQRIQQWQQSPC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 IAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGDSDDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGDSDDT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 DLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNPQSKT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 YCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKLRRAE
550 560 570 580 590 600
610 620 630 640 650
pF1KB7 VDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR
610 620 630 640 650
>>NP_001095124 (OMIM: 609150) CXXC-type zinc finger prot (660 aa)
initn: 2553 init1: 2481 opt: 4659 Z-score: 3210.9 bits: 604.4 E(85289): 4.2e-172
Smith-Waterman score: 4659; 99.4% identity (99.4% similar) in 660 aa overlap (1-656:1-660)
10 20 30 40 50 60
pF1KB7 MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQIKRSARMCGECEACRRTED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQIKRSARMCGECEACRRTED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 CGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFD
250 260 270 280 290 300
310 320 330 340 350
pF1KB7 DHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKK----KEERYKRHRQKQKHKD
:::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
NP_001 DHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKKVMERKEERYKRHRQKQKHKD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 KWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLAANRIYEILPQRIQQWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLAANRIYEILPQRIQQWQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB7 QSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGD
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB7 SDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB7 QSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB7 RRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR
610 620 630 640 650 660
>>XP_011524242 (OMIM: 609150) PREDICTED: CXXC-type zinc (660 aa)
initn: 2553 init1: 2481 opt: 4659 Z-score: 3210.9 bits: 604.4 E(85289): 4.2e-172
Smith-Waterman score: 4659; 99.4% identity (99.4% similar) in 660 aa overlap (1-656:1-660)
10 20 30 40 50 60
pF1KB7 MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMIGCDNCNEWFHGDCIRITEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 MAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAKAIREWYCRECREKDPKLEIRYRHKKSRERDGNERDSSEPRDEGGGRKRPVPDPDLQR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQIKRSARMCGECEACRRTED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAGSGTGVGAMLARGSASPHKSSPQPLVATPSQHHQQQQQQIKRSARMCGECEACRRTED
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 CGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFPSSLSPVTPSESLPRPRRPLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 TQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLSDEDLPLDPDLYQDFCAGAFD
250 260 270 280 290 300
310 320 330 340 350
pF1KB7 DHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKK----KEERYKRHRQKQKHKD
:::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_011 DHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKKVMERKEERYKRHRQKQKHKD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 KWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLAANRIYEILPQRIQQWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLAANRIYEILPQRIQQWQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB7 QSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILRAKQQAVREDEESNEGD
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB7 SDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYPTRIEGATRLFCDVYNP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB7 QSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFCRLPKRQCNRHYCWEKL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB7 RRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQTIQHDPLTTDLRSSADR
610 620 630 640 650 660
>>XP_016881208 (OMIM: 609150) PREDICTED: CXXC-type zinc (531 aa)
initn: 3564 init1: 3564 opt: 3566 Z-score: 2462.1 bits: 465.6 E(85289): 2.1e-130
Smith-Waterman score: 3566; 96.6% identity (97.9% similar) in 526 aa overlap (135-656:6-531)
110 120 130 140 150 160
pF1KB7 EGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSASPH-KSSPQPL---VATPSQHHQQQQQ
:.:: . :.: .. ..:::::::
XP_016 MSGSMGTASGSLRRWPRPSGSGTVGSAEHHQQQQQ
10 20 30
170 180 190 200 210 220
pF1KB7 QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFP
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB7 SSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLS
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB7 DEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKK
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB7 KEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCGMKLA
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB7 ANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEAIILR
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB7 AKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFGSMYP
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB7 TRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELTGDFC
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB7 RLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALMLHQT
460 470 480 490 500 510
650
pF1KB7 IQHDPLTTDLRSSADR
::::::::::::::::
XP_016 IQHDPLTTDLRSSADR
520 530
>>XP_011524243 (OMIM: 609150) PREDICTED: CXXC-type zinc (535 aa)
initn: 2330 init1: 2253 opt: 3548 Z-score: 2449.7 bits: 463.3 E(85289): 1e-129
Smith-Waterman score: 3548; 95.8% identity (97.2% similar) in 530 aa overlap (135-656:6-535)
110 120 130 140 150 160
pF1KB7 EGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSASPH-KSSPQPL---VATPSQHHQQQQQ
:.:: . :.: .. ..:::::::
XP_011 MSGSMGTASGSLRRWPRPSGSGTVGSAEHHQQQQQ
10 20 30
170 180 190 200 210 220
pF1KB7 QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARESYKYFP
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB7 SSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSTVKEPPEATATPEPLS
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB7 DEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRREKKSEKK
160 170 180 190 200 210
350 360 370 380 390
pF1KB7 ----KEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMERKEERYKRHRQKQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSDDCG
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB7 MKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHELEA
280 290 300 310 320 330
460 470 480 490 500 510
pF1KB7 IILRAKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IILRAKQQAVREDEESNEGDSDDTDLQIFCVSCGHPINPRVALRHMERCYAKYESQTSFG
340 350 360 370 380 390
520 530 540 550 560 570
pF1KB7 SMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMYPTRIEGATRLFCDVYNPQSKTYCKRLQVLCPEHSRDPKVPADEVCGCPLVRDVFELT
400 410 420 430 440 450
580 590 600 610 620 630
pF1KB7 GDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDFCRLPKRQCNRHYCWEKLRRAEVDLERVRVWYKLDELFEQERNVRTAMTNRAGLLALM
460 470 480 490 500 510
640 650
pF1KB7 LHQTIQHDPLTTDLRSSADR
::::::::::::::::::::
XP_011 LHQTIQHDPLTTDLRSSADR
520 530
>>NP_001310878 (OMIM: 156535) methyl-CpG-binding domain (461 aa)
initn: 271 init1: 237 opt: 305 Z-score: 225.1 bits: 51.4 E(85289): 8.4e-06
Smith-Waterman score: 330; 26.3% identity (46.3% similar) in 391 aa overlap (27-394:37-399)
10 20 30 40 50
pF1KB7 MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMI-----GCDNC-NEWF
..: :.. :. : :: : .
NP_001 CGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERR--RCLRIVERSRGCGVCRGCQT
10 20 30 40 50 60
60 70 80 90 100
pF1KB7 HGDC----IRITEKMAKAIREWYC--RECREKDPKLEIRYRHKKSRERDGNERDSSEPRD
. :: : . :.: : :.: .. . ..: ::.. ..: . . :
NP_001 QEDCGHCPICLRPPRPGLRRQWKCVQRRCLRHLAH-RLRRRHQRCQRR--TPLAVAPPTG
70 80 90 100 110 120
110 120 130 140 150
pF1KB7 EGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPS----------QH
. . :: . :: .. . : ::. . :.: . .:: ..
NP_001 KHARRKGGCDSKMAARRRPGAQPLPP--PPPSQSPEPTEPHPRALAPSPPAEFIYYCVDE
130 140 150 160 170
160 170 180 190 200 210
pF1KB7 HQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARE
. : .:. : :: : :: : :::.:::: : :::: :. ::::: :::
NP_001 DELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQC------
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB7 SYKYFPSSLSPVTPSESLPRPRRPLPTQQQPQPSQKLGRIREDEGAVASSTVKEPPEATA
.. . : : . ::: : : ... .::. .: :. : :.: : ::
NP_001 -LQFAMKRLLPSVWSESEDGAGSPPPYRRRKRPSS--AR-RHHLGP----TLK-PTLATR
240 250 260 270 280
280 290 300 310 320 330
pF1KB7 TPEPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKVKHVKRRE
: .: . . : . : : .. . :: :. :.... . ..
NP_001 TAQP-DHTQAPTKQEAGGGFVLPP-PGTDLVFLREGASSPVQVPG--PVAASTEALLQEA
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB7 KKSEKKKEERYKRHRQ-KQKHKDKWKHPERADAKDPASLPQCLGPGCVRPAQPSSKYCSD
. : . . .: : .:.: : : .:. .: : . . : :. :: :
NP_001 QCSGLSWVVALPQVKQEKADTQDEWT-PGTAVLTSPVLVPGCPSKA-VDPGLPSVKQEPP
350 360 370 380 390
400 410 420 430 440 450
pF1KB7 DCGMKLAANRIYEILPQRIQQWQQSPCIAEEHGKKLLERIRREQQSARTRLQEMERRFHE
:
NP_001 DPEEDKEENKDDSASKLAPEEEAGGAGTPVITEIFSLGGTRFRDTAVWLPRSKDLKKPGA
400 410 420 430 440 450
>>XP_011524304 (OMIM: 156535) PREDICTED: methyl-CpG-bind (584 aa)
initn: 237 init1: 237 opt: 305 Z-score: 223.8 bits: 51.5 E(85289): 1e-05
Smith-Waterman score: 314; 27.5% identity (47.5% similar) in 284 aa overlap (27-281:206-480)
10 20 30 40 50
pF1KB7 MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMI-----GCDNC-NEWF
..: :.. :. : :: : .
XP_011 CGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERR--RCLRIVERSRGCGVCRGCQT
180 190 200 210 220 230
60 70 80 90 100
pF1KB7 HGDC----IRITEKMAKAIREWYC--RECREKDPKLEIRYRHKKSRERDGNERDSSEPRD
. :: : . :.: : :.: .. . ..: ::.. ..: . . :
XP_011 QEDCGHCPICLRPPRPGLRRQWKCVQRRCLRHLAH-RLRRRHQRCQRR--TPLAVAPPTG
240 250 260 270 280 290
110 120 130 140 150
pF1KB7 EGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPS----------QH
. . :: . :: .. . : ::. . :.: . .:: ..
XP_011 KHARRKGGCDSKMAARRRPGAQPLPP--PPPSQSPEPTEPHPRALAPSPPAEFIYYCVDE
300 310 320 330 340
160 170 180 190 200 210
pF1KB7 HQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARE
. : .:. : :: : :: : :::.:::: : :::: :. ::::: ::: : .
XP_011 DELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMK
350 360 370 380 390 400
220 230 240 250 260
pF1KB7 SYKYFPSSLSPVTPSESLPRP--RRPLPTQQQPQ---PSQK--LGRIREDEGAVASSTVK
. .:: : . . : : :: :.. . . :. : :. . . . : .
XP_011 --RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQ
410 420 430 440 450 460
270 280 290 300 310 320
pF1KB7 EPPEATATPEPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKV
: . . : : .:
XP_011 EAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEED
470 480 490 500 510 520
>>XP_016881253 (OMIM: 156535) PREDICTED: methyl-CpG-bind (584 aa)
initn: 237 init1: 237 opt: 305 Z-score: 223.8 bits: 51.5 E(85289): 1e-05
Smith-Waterman score: 314; 27.5% identity (47.5% similar) in 284 aa overlap (27-281:206-480)
10 20 30 40 50
pF1KB7 MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMI-----GCDNC-NEWF
..: :.. :. : :: : .
XP_016 CGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERR--RCLRIVERSRGCGVCRGCQT
180 190 200 210 220 230
60 70 80 90 100
pF1KB7 HGDC----IRITEKMAKAIREWYC--RECREKDPKLEIRYRHKKSRERDGNERDSSEPRD
. :: : . :.: : :.: .. . ..: ::.. ..: . . :
XP_016 QEDCGHCPICLRPPRPGLRRQWKCVQRRCLRHLAH-RLRRRHQRCQRR--TPLAVAPPTG
240 250 260 270 280 290
110 120 130 140 150
pF1KB7 EGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPS----------QH
. . :: . :: .. . : ::. . :.: . .:: ..
XP_016 KHARRKGGCDSKMAARRRPGAQPLPP--PPPSQSPEPTEPHPRALAPSPPAEFIYYCVDE
300 310 320 330 340
160 170 180 190 200 210
pF1KB7 HQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARE
. : .:. : :: : :: : :::.:::: : :::: :. ::::: ::: : .
XP_016 DELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMK
350 360 370 380 390 400
220 230 240 250 260
pF1KB7 SYKYFPSSLSPVTPSESLPRP--RRPLPTQQQPQ---PSQK--LGRIREDEGAVASSTVK
. .:: : . . : : :: :.. . . :. : :. . . . : .
XP_016 --RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQ
410 420 430 440 450 460
270 280 290 300 310 320
pF1KB7 EPPEATATPEPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKV
: . . : : .:
XP_016 EAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEED
470 480 490 500 510 520
>>XP_011524305 (OMIM: 156535) PREDICTED: methyl-CpG-bind (584 aa)
initn: 237 init1: 237 opt: 305 Z-score: 223.8 bits: 51.5 E(85289): 1e-05
Smith-Waterman score: 314; 27.5% identity (47.5% similar) in 284 aa overlap (27-281:206-480)
10 20 30 40 50
pF1KB7 MEGDGSDPEPPDAGEDSKSENGENAPIYCICRKPDINCFMI-----GCDNC-NEWF
..: :.. :. : :: : .
XP_011 CGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERR--RCLRIVERSRGCGVCRGCQT
180 190 200 210 220 230
60 70 80 90 100
pF1KB7 HGDC----IRITEKMAKAIREWYC--RECREKDPKLEIRYRHKKSRERDGNERDSSEPRD
. :: : . :.: : :.: .. . ..: ::.. ..: . . :
XP_011 QEDCGHCPICLRPPRPGLRRQWKCVQRRCLRHLAH-RLRRRHQRCQRR--TPLAVAPPTG
240 250 260 270 280 290
110 120 130 140 150
pF1KB7 EGGGRKRPVPDPDLQRRAGSGTGVGAMLARGSASPHKSSPQPLVATPS----------QH
. . :: . :: .. . : ::. . :.: . .:: ..
XP_011 KHARRKGGCDSKMAARRRPGAQPLPP--PPPSQSPEPTEPHPRALAPSPPAEFIYYCVDE
300 310 320 330 340
160 170 180 190 200 210
pF1KB7 HQQQQQQIKRSARMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARE
. : .:. : :: : :: : :::.:::: : :::: :. ::::: ::: : .
XP_011 DELQPYTNRRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMK
350 360 370 380 390 400
220 230 240 250 260
pF1KB7 SYKYFPSSLSPVTPSESLPRP--RRPLPTQQQPQ---PSQK--LGRIREDEGAVASSTVK
. .:: : . . : : :: :.. . . :. : :. . . . : .
XP_011 --RLLPSVWSESEDGAGSPPPYRRRKRPSSARRHHLGPTLKPTLATRTAQPDHTQAPTKQ
410 420 430 440 450 460
270 280 290 300 310 320
pF1KB7 EPPEATATPEPLSDEDLPLDPDLYQDFCAGAFDDHGLPWMSDTEESPFLDPALRKRAVKV
: . . : : .:
XP_011 EAGGGFVLPPPGTDLVFLREGASSPVQVPGPVAASTEALLQAVDPGLPSVKQEPPDPEED
470 480 490 500 510 520
656 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 10:01:18 2016 done: Sat Nov 5 10:01:20 2016
Total Scan time: 10.320 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]