Result of FASTA (omim) for
pF1KB7821
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7821, 536 aa
1>>>pF1KB7821 536 - 536 aa - 536 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0091+/-0.000424; mu= 5.3882+/- 0.026
mean_var=131.8578+/-25.757, 0's: 0 Z-trim(114.4): 39 B-trim: 70 in 1/56
Lambda= 0.111692
statistics sampled from 24156 (24185) to 24156 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.639), E-opt: 0.2 (0.284), width: 16
Scan time: 10.890
The best scores are: opt bits E(85289)
NP_004497 (OMIM: 140581) heat shock factor protein ( 536) 3453 568.2 2.2e-161
NP_001129036 (OMIM: 140581) heat shock factor prot ( 518) 2554 423.3 8.6e-118
NP_001230023 (OMIM: 140581) heat shock factor prot ( 230) 1477 249.7 7.3e-66
XP_016868866 (OMIM: 140580) PREDICTED: heat shock ( 489) 837 146.7 1.6e-34
XP_005272373 (OMIM: 140580) PREDICTED: heat shock ( 517) 837 146.7 1.7e-34
NP_005517 (OMIM: 140580) heat shock factor protein ( 529) 837 146.7 1.7e-34
XP_005272372 (OMIM: 140580) PREDICTED: heat shock ( 557) 837 146.7 1.8e-34
XP_005272374 (OMIM: 140580) PREDICTED: heat shock ( 310) 827 145.0 3.2e-34
NP_001035757 (OMIM: 116800,602438) heat shock fact ( 492) 670 119.8 2e-26
NP_001529 (OMIM: 116800,602438) heat shock factor ( 462) 649 116.4 2e-25
XP_011515308 (OMIM: 140580) PREDICTED: heat shock ( 272) 183 41.2 0.005
XP_011515306 (OMIM: 140580) PREDICTED: heat shock ( 346) 183 41.2 0.0061
>>NP_004497 (OMIM: 140581) heat shock factor protein 2 i (536 aa)
initn: 3453 init1: 3453 opt: 3453 Z-score: 3018.4 bits: 568.2 E(85289): 2.2e-161
Smith-Waterman score: 3453; 100.0% identity (100.0% similar) in 536 aa overlap (1-536:1-536)
10 20 30 40 50 60
pF1KB7 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 RISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 SGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 LDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDLFTSSVQMNPTDYINNTKSENKGLETTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDLFTSSVQMNPTDYINNTKSENKGLETTK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 NNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKP
430 440 450 460 470 480
490 500 510 520 530
pF1KB7 IEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS
490 500 510 520 530
>>NP_001129036 (OMIM: 140581) heat shock factor protein (518 aa)
initn: 3324 init1: 2548 opt: 2554 Z-score: 2235.7 bits: 423.3 E(85289): 8.6e-118
Smith-Waterman score: 3292; 96.6% identity (96.6% similar) in 536 aa overlap (1-536:1-518)
10 20 30 40 50 60
pF1KB7 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 RISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 SGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTMMDSILNDNINLLGKVEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 LDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDLFTSSVQMNPTDYINNTKSENKGLETTK
:::::::::::::::::::::::::::::::: ::::::::::
NP_001 LDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVD------------------SENKGLETTK
370 380 390 400
430 440 450 460 470 480
pF1KB7 NNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKP
410 420 430 440 450 460
490 500 510 520 530
pF1KB7 IEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS
470 480 490 500 510
>>NP_001230023 (OMIM: 140581) heat shock factor protein (230 aa)
initn: 1477 init1: 1477 opt: 1477 Z-score: 1303.5 bits: 249.7 E(85289): 7.3e-66
Smith-Waterman score: 1477; 100.0% identity (100.0% similar) in 228 aa overlap (1-228:1-228)
10 20 30 40 50 60
pF1KB7 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKYFKHNNMAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVRQLNMYGFRKVVHIDSGIVKQERDGPVEFQHPYFKQGQDDLLENIKRKVSSSKPEENK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHAQQQQVIRKIVQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVPHSRTEGLKPRE
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIVTLVQNNQLVSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKVIF
190 200 210 220 230
250 260 270 280 290 300
pF1KB7 RISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVEDDNEDEYAPVIQ
>>XP_016868866 (OMIM: 140580) PREDICTED: heat shock fact (489 aa)
initn: 657 init1: 493 opt: 837 Z-score: 740.9 bits: 146.7 E(85289): 1.6e-34
Smith-Waterman score: 967; 38.8% identity (64.3% similar) in 487 aa overlap (5-462:13-489)
10 20 30 40 50
pF1KB7 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKY
:::::::.:::::: . :. .: :: .:.:: :.:. .::::.::::
XP_016 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 FKHNNMASFVRQLNMYGFRKVVHIDSG-IVKQERDGPVEFQHPYFKQGQDDLLENIKRKV
::::::::::::::::::::::::..: .:: ::: .::::: : .::..:::::::::
XP_016 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDD-TEFQHPCFLRGQEQLLENIKRKV
70 80 90 100 110
120 130 140 150 160
pF1KB7 SSS---KPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKH
.: : :. ::::...::.....: .. ::: ..:.: .: :::.::.::. :: ::
XP_016 TSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 AQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAQK---KNLFQHIVKEPTDNHH
::::.:. :..::...:::.:.....::: ::.:: .:. . : : ... .
XP_016 AQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 HKVP---HSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYP
...: .: . : :. :: :.: : :. : .. : :. :
XP_016 YSAPSPAYSSSSLYAPDAVASSGPIISDIT------ELAPASPMASPGGSIDERPLSSSP
240 250 260 270 280 290
290 300 310 320 330
pF1KB7 DIVIVEDDNEDEYAPVIQSGEQNEPAR-ESLSSGS---DG----SSPLMSSAVQLNGSSS
. . :. .: .. . ..:. ..: : . :. : : .:.. :. . .
XP_016 LVRVKEEPPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARG
300 310 320 330 340 350
340 350 360 370 380
pF1KB7 LT-------SEDPVTMMDSILNDNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDP
: : :.. .. : .. : : :: :.::..: .:...:.:::.. ::.:
XP_016 HTDTEGRPPSPPPTSTPEKCL--SVACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDT
360 370 380 390 400 410
390 400 410 420 430 440
pF1KB7 DLLVDLFTSSVQMNPTDYINNTKSENKGLETTKNNVVQPVSEEGRKSKSKPDKQLIQYTA
. :.:::. :: . : . . : ... . : :...:. : . .:
XP_016 SALLDLFSPSVTV-PDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSAGALHSAAA
420 430 440 450 460 470
450 460 470 480 490 500
pF1KB7 FPLLAFLDGN----PASSVEQASTTASSEVLSSVDKPIEVDELLDSSLDPEPTQSKLVRL
: : :. ::..:
XP_016 VPAGPRLRGHREQRPAGAV
480
>>XP_005272373 (OMIM: 140580) PREDICTED: heat shock fact (517 aa)
initn: 976 init1: 493 opt: 837 Z-score: 740.5 bits: 146.7 E(85289): 1.7e-34
Smith-Waterman score: 918; 37.2% identity (61.6% similar) in 513 aa overlap (5-462:13-517)
10 20 30 40 50
pF1KB7 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKY
:::::::.:::::: . :. .: :: .:.:: :.:. .::::.::::
XP_005 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 FKHNNMASFVRQLNMYGFRKVVHIDSG-IVKQERDGPVEFQHPYFKQGQDDLLENIKRKV
::::::::::::::::::::::::..: .:: ::: .::::: : .::..:::::::::
XP_005 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDD-TEFQHPCFLRGQEQLLENIKRKV
70 80 90 100 110
120 130 140 150 160
pF1KB7 SSS---KPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKH
.: : :. ::::...::.....: .. ::: ..:.: .: :::.::.::. :: ::
XP_005 TSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 AQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAQK---KNLFQHIVKEPTDNHH
::::.:. :..::...:::.:.....::: ::.:: .:. . : : ... .
XP_005 AQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 HKVP---HSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYP
...: .: . : :. :: :.: : :. : .. : :. :
XP_005 YSAPSPAYSSSSLYAPDAVASSGPIISDIT------ELAPASPMASPGGSIDERPLSSSP
240 250 260 270 280 290
290 300 310 320 330
pF1KB7 DIVIVEDDNEDEYAPVIQSGEQNEPAR-ESLSSGS---DG----SSPLMSSAVQLNGSSS
. . :. .: .. . ..:. ..: : . :. : : .:.. :. . .
XP_005 LVRVKEEPPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARG
300 310 320 330 340 350
340 350 360
pF1KB7 LT-------SEDPVTMMDSILN----DNINLL------------------GKV----ELL
: : :.. .. :. ::. :.: ::
XP_005 HTDTEGRPPSPPPTSTPEKCLSVACLDNLARTPQMSRVARLFPCPSSSPHGQVQPGNELS
360 370 380 390 400 410
370 380 390 400 410 420
pF1KB7 DYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDLFTSSVQMNPTDYINNTKSENKGLETTKN
:.::..: .:...:.:::.. ::.: . :.:::. :: . : . . : ... .
XP_005 DHLDAMDSNLDNLQTMLSSHGFSVDTSALLDLFSPSVTV-PDMSLPDLDSSLASIQELLS
420 430 440 450 460 470
430 440 450 460 470
pF1KB7 NVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGN----PASSVEQASTTASSEVLSSV
: :...:. : . .: : : :. ::..:
XP_005 PQEPPRPPEAENSSPDSAGALHSAAAVPAGPRLRGHREQRPAGAV
480 490 500 510
480 490 500 510 520 530
pF1KB7 DKPIEVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS
>>NP_005517 (OMIM: 140580) heat shock factor protein 1 [ (529 aa)
initn: 706 init1: 493 opt: 837 Z-score: 740.3 bits: 146.7 E(85289): 1.7e-34
Smith-Waterman score: 1009; 39.7% identity (65.7% similar) in 478 aa overlap (5-457:13-480)
10 20 30 40 50
pF1KB7 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKY
:::::::.:::::: . :. .: :: .:.:: :.:. .::::.::::
NP_005 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 FKHNNMASFVRQLNMYGFRKVVHIDSG-IVKQERDGPVEFQHPYFKQGQDDLLENIKRKV
::::::::::::::::::::::::..: .:: ::: .::::: : .::..:::::::::
NP_005 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDD-TEFQHPCFLRGQEQLLENIKRKV
70 80 90 100 110
120 130 140 150 160
pF1KB7 SSS---KPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKH
.: : :. ::::...::.....: .. ::: ..:.: .: :::.::.::. :: ::
NP_005 TSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 AQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAQK---KNLFQHIVKEPTDNHH
::::.:. :..::...:::.:.....::: ::.:: .:. . : : ... .
NP_005 AQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 HKVP---HSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYP
...: .: . : :. :: :.: : :. : .. : :. :
NP_005 YSAPSPAYSSSSLYAPDAVASSGPIISDIT------ELAPASPMASPGGSIDERPLSSSP
240 250 260 270 280 290
290 300 310 320 330
pF1KB7 DIVIVEDDNEDEYAPVIQSGEQNEPAR-ESLSSGS---DG----SSPLMSSAVQLNGSSS
. . :. .: .. . ..:. ..: : . :. : : .:.. :. . .
NP_005 LVRVKEEPPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARG
300 310 320 330 340 350
340 350 360 370 380
pF1KB7 LT-------SEDPVTMMDSILNDNINLLGKVELLDYLDSIDCSLEDFQAMLSGRQFSIDP
: : :.. .. : .. : : :: :.::..: .:...:.:::.. ::.:
NP_005 HTDTEGRPPSPPPTSTPEKCL--SVACLDKNELSDHLDAMDSNLDNLQTMLSSHGFSVDT
360 370 380 390 400 410
390 400 410 420 430 440
pF1KB7 DLLVDLFTSSVQMNPTDYINNTKSENKGLETTKNNVVQPVSEEGRKSKSKPDKQLIQYTA
. :.:::. :: . : . . : ... . : :...:. :::..:::
NP_005 SALLDLFSPSVTV-PDMSLPDLDSSLASIQELLSPQEPPRPPEAENSSPDSGKQLVHYTA
420 430 440 450 460 470
450 460 470 480 490 500
pF1KB7 FPLLAFLDGNPASSVEQASTTASSEVLSSVDKPIEVDELLDSSLDPEPTQSKLVRLEPLT
::. . :.
NP_005 QPLFLLDPGSVDTGSNDLPVLFELGEGSYFSEGDGFAEDPTISLLTGSEPPKAKDPTVS
480 490 500 510 520
>>XP_005272372 (OMIM: 140580) PREDICTED: heat shock fact (557 aa)
initn: 1025 init1: 493 opt: 837 Z-score: 739.9 bits: 146.7 E(85289): 1.8e-34
Smith-Waterman score: 960; 38.1% identity (62.9% similar) in 504 aa overlap (5-457:13-508)
10 20 30 40 50
pF1KB7 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKY
:::::::.:::::: . :. .: :: .:.:: :.:. .::::.::::
XP_005 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 FKHNNMASFVRQLNMYGFRKVVHIDSG-IVKQERDGPVEFQHPYFKQGQDDLLENIKRKV
::::::::::::::::::::::::..: .:: ::: .::::: : .::..:::::::::
XP_005 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDD-TEFQHPCFLRGQEQLLENIKRKV
70 80 90 100 110
120 130 140 150 160
pF1KB7 SSS---KPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKH
.: : :. ::::...::.....: .. ::: ..:.: .: :::.::.::. :: ::
XP_005 TSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 AQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAQK---KNLFQHIVKEPTDNHH
::::.:. :..::...:::.:.....::: ::.:: .:. . : : ... .
XP_005 AQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 HKVP---HSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYP
...: .: . : :. :: :.: : :. : .. : :. :
XP_005 YSAPSPAYSSSSLYAPDAVASSGPIISDIT------ELAPASPMASPGGSIDERPLSSSP
240 250 260 270 280 290
290 300 310 320 330
pF1KB7 DIVIVEDDNEDEYAPVIQSGEQNEPAR-ESLSSGS---DG----SSPLMSSAVQLNGSSS
. . :. .: .. . ..:. ..: : . :. : : .:.. :. . .
XP_005 LVRVKEEPPSPPQSPRVEEASPGRPSSVDTLLSPTALIDSILRESEPAPASVTALTDARG
300 310 320 330 340 350
340 350 360
pF1KB7 LT-------SEDPVTMMDSILN----DNINLL------------------GKV----ELL
: : :.. .. :. ::. :.: ::
XP_005 HTDTEGRPPSPPPTSTPEKCLSVACLDNLARTPQMSRVARLFPCPSSSPHGQVQPGNELS
360 370 380 390 400 410
370 380 390 400 410 420
pF1KB7 DYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDLFTSSVQMNPTDYINNTKSENKGLETTKN
:.::..: .:...:.:::.. ::.: . :.:::. :: . : . . : ... .
XP_005 DHLDAMDSNLDNLQTMLSSHGFSVDTSALLDLFSPSVTV-PDMSLPDLDSSLASIQELLS
420 430 440 450 460 470
430 440 450 460 470 480
pF1KB7 NVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASSVEQASTTASSEVLSSVDKPI
: :...:. :::..::: ::. . :.
XP_005 PQEPPRPPEAENSSPDSGKQLVHYTAQPLFLLDPGSVDTGSNDLPVLFELGEGSYFSEGD
480 490 500 510 520 530
490 500 510 520 530
pF1KB7 EVDELLDSSLDPEPTQSKLVRLEPLTEAEASEATLFYLCELAPAPLDSDMPLLDS
XP_005 GFAEDPTISLLTGSEPPKAKDPTVS
540 550
>>XP_005272374 (OMIM: 140580) PREDICTED: heat shock fact (310 aa)
initn: 821 init1: 493 opt: 827 Z-score: 735.3 bits: 145.0 E(85289): 3.2e-34
Smith-Waterman score: 830; 51.7% identity (76.8% similar) in 259 aa overlap (5-253:13-270)
10 20 30 40 50
pF1KB7 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILPKY
:::::::.:::::: . :. .: :: .:.:: :.:. .::::.::::
XP_005 MDLPVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 FKHNNMASFVRQLNMYGFRKVVHIDSG-IVKQERDGPVEFQHPYFKQGQDDLLENIKRKV
::::::::::::::::::::::::..: .:: ::: .::::: : .::..:::::::::
XP_005 FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDD-TEFQHPCFLRGQEQLLENIKRKV
70 80 90 100 110
120 130 140 150 160
pF1KB7 SSS---KPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKH
.: : :. ::::...::.....: .. ::: ..:.: .: :::.::.::. :: ::
XP_005 TSVSTLKSEDIKIRQDSVTKLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 AQQQQVIRKIVQFIVTLVQNNQLVSLKRKRPLLLNTNGAQK---KNLFQHIVKEPTDNHH
::::.:. :..::...:::.:.....::: ::.:: .:. . : : ... .
XP_005 AQQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLNDSGSAHSMPKYSRQFSLEHVHGSGP
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 HKVP---HSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYP
...: .: . : :. :: :.:.
XP_005 YSAPSPAYSSSSLYAPDAVASSGPIISDITELAPASPMASPGGSIDESPHGRQGPHGHRG
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 DIVIVEDDNEDEYAPVIQSGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVT
XP_005 PASLPPAHLHP
300 310
>>NP_001035757 (OMIM: 116800,602438) heat shock factor p (492 aa)
initn: 674 init1: 625 opt: 670 Z-score: 595.4 bits: 119.8 E(85289): 2e-26
Smith-Waterman score: 670; 34.4% identity (63.1% similar) in 404 aa overlap (5-399:15-403)
10 20 30 40 50
pF1KB7 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILP
: :::::.:::.:: . :...: :: .: :::: :..:::::.::
NP_001 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
10 20 30 40 50 60
60 70 80 90 100
pF1KB7 KYFKHNNMASFVRQLNMYGFRKVVHIDSG-IVKQERDGPVEFQHPYFKQGQDDLLENIKR
.::::.:::::::::::::::::: :..: ... ::: :::::: : .:...::: ..:
NP_001 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDH-VEFQHPSFVRGREQLLERVRR
70 80 90 100 110
110 120 130 140 150 160
pF1KB7 KVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHA
:: . . .... : ::: .... .: .. ::. :.:: ::...:: ::.:: :: .:.
NP_001 KVPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 QQQQVIRKIVQFIVTLVQNNQL-VSLKRKRPLLLNTNGAQKKNLFQHIVKEP----TDNH
::..:: :..: . .: . .. ::: :.:. ... . : : .
NP_001 QQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPY
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 HHKVPHSRTE-GLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPD
. : .:. ::.:.. . :: :. .:. . :: .. .: :. .
NP_001 FIQSPLPETNLGLSPHR--ARGPIISDIPEDSPS-------PEGTR--LSPSSDGRREKG
240 250 260 270 280
290 300 310 320 330 340
pF1KB7 IVIVEDDNEDEYAPVIQSGEQNEPARESLSSGSDGSSPLMSSAVQLNGSSSLTSEDPVTM
....... . . ..: : . .. . :. . :.:..:.. : : .
NP_001 LALLKEEPASPGGDG-EAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSFSPEGPRNA
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB7 MDSILNDNINLLGKVELLDYLDSIDCSLEDF--QAMLSGRQFSIDPDLLVDLFTSSVQMN
.. .: .. . : :.: : : :.. .:. : :..: .:.. :.:
NP_001 QQPEPGDPREIPDRGPL--GLESGDRSPESLLPPMLLQPPQESVEPAGPLDVLGPSLQGR
350 360 370 380 390 400
410 420 430 440 450 460
pF1KB7 PTDYINNTKSENKGLETTKNNVVQPVSEEGRKSKSKPDKQLIQYTAFPLLAFLDGNPASS
NP_001 EWTLMDLDMELSLMQPLVPERGEPELAVKGLNSPSPGKDPTLGAPLLLDVQAALGGPALG
410 420 430 440 450 460
>>NP_001529 (OMIM: 116800,602438) heat shock factor prot (462 aa)
initn: 649 init1: 625 opt: 649 Z-score: 577.5 bits: 116.4 E(85289): 2e-25
Smith-Waterman score: 649; 50.7% identity (78.1% similar) in 201 aa overlap (5-203:15-214)
10 20 30 40 50
pF1KB7 MKQSSNVPAFLSKLWTLVEETHTNEFITWSQNGQSFLVLDEQRFAKEILP
: :::::.:::.:: . :...: :: .: :::: :..:::::.::
NP_001 MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
10 20 30 40 50 60
60 70 80 90 100
pF1KB7 KYFKHNNMASFVRQLNMYGFRKVVHIDSG-IVKQERDGPVEFQHPYFKQGQDDLLENIKR
.::::.:::::::::::::::::: :..: ... ::: :::::: : .:...::: ..:
NP_001 QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDH-VEFQHPSFVRGREQLLERVRR
70 80 90 100 110
110 120 130 140 150 160
pF1KB7 KVSSSKPEENKIRQEDLTKIISSAQKVQIKQETIESRLSELKSENESLWKEVSELRAKHA
:: . . .... : ::: .... .: .. ::. :.:: ::...:: ::.:: :: .:.
NP_001 KVPALRGDDGRWRPEDLGRLLGEVQALRGVQESTEARLRELRQQNEILWREVVTLRQSHG
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 QQQQVIRKIVQFIVTLVQNNQL-VSLKRKRPLLLNTNGAQKKNLFQHIVKEPTDNHHHKV
::..:: :..: . .: . .. ::: :.:.
NP_001 QQHRVIGKLIQCLFGPLQAGPSNAGGKRKLSLMLDEGSSCPTPAKFNTCPLPGALLQDPY
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 PHSRTEGLKPRERISDDIIIYDVTDDNADEENIPVIPETNEDVISDPSNCSQYPDIVIVE
NP_001 FIQSPSTYSLSQRQIWALALTGPGAPSSLTSQKTLHPLRGPGFLPPVMAGAPPPLPVAVV
240 250 260 270 280 290
536 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:26:25 2016 done: Fri Nov 4 22:26:27 2016
Total Scan time: 10.890 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]