Result of FASTA (omim) for
pF1KB7789
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7789, 458 aa
1>>>pF1KB7789 458 - 458 aa - 458 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8665+/-0.000336; mu= 12.3326+/- 0.021
mean_var=130.0073+/-25.801, 0's: 0 Z-trim(118.8): 40 B-trim: 0 in 0/57
Lambda= 0.112484
statistics sampled from 32074 (32114) to 32074 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.377), width: 16
Scan time: 5.540
The best scores are: opt bits E(85289)
NP_115564 (OMIM: 609912) histone acetyltransferase ( 458) 3114 516.4 6.2e-146
NP_892003 (OMIM: 609912) histone acetyltransferase ( 467) 2966 492.4 1.1e-138
XP_011544272 (OMIM: 609912) PREDICTED: histone ace ( 300) 2066 346.2 7e-95
XP_011544273 (OMIM: 609912) PREDICTED: histone ace ( 300) 2066 346.2 7e-95
NP_001186087 (OMIM: 609880) histone acetyltransfer ( 442) 1164 200.0 1.1e-50
NP_001186085 (OMIM: 609880) histone acetyltransfer ( 472) 1164 200.0 1.2e-50
NP_001186086 (OMIM: 609880) histone acetyltransfer ( 501) 1164 200.0 1.2e-50
NP_001186084 (OMIM: 609880) histone acetyltransfer ( 581) 1164 200.1 1.4e-50
NP_008998 (OMIM: 609880) histone acetyltransferase ( 611) 1164 200.1 1.4e-50
XP_011522537 (OMIM: 609880) PREDICTED: histone ace ( 328) 1153 198.1 3e-50
NP_874368 (OMIM: 601409) histone acetyltransferase ( 461) 1077 185.9 2e-46
NP_001193762 (OMIM: 601409) histone acetyltransfer ( 494) 1077 185.9 2.1e-46
NP_006379 (OMIM: 601409) histone acetyltransferase ( 513) 1077 185.9 2.2e-46
XP_006718484 (OMIM: 601409) PREDICTED: histone ace ( 522) 1077 185.9 2.2e-46
NP_874369 (OMIM: 601409) histone acetyltransferase ( 546) 1077 185.9 2.3e-46
NP_001292807 (OMIM: 601408,616268) histone acetylt ( 815) 1049 181.5 7.3e-45
NP_006757 (OMIM: 601408,616268) histone acetyltran (2004) 1049 181.8 1.5e-44
XP_016869353 (OMIM: 601408,616268) PREDICTED: hist (2004) 1049 181.8 1.5e-44
XP_016869352 (OMIM: 601408,616268) PREDICTED: hist (2004) 1049 181.8 1.5e-44
XP_011542961 (OMIM: 601408,616268) PREDICTED: hist (2041) 1049 181.8 1.5e-44
XP_011542959 (OMIM: 601408,616268) PREDICTED: hist (2048) 1049 181.8 1.5e-44
XP_011542958 (OMIM: 601408,616268) PREDICTED: hist (2048) 1049 181.8 1.5e-44
XP_011542960 (OMIM: 601408,616268) PREDICTED: hist (2048) 1049 181.8 1.5e-44
NP_001243398 (OMIM: 603736,605880,606170) histone (1781) 970 168.9 9.6e-41
XP_016871496 (OMIM: 603736,605880,606170) PREDICTE (1781) 970 168.9 9.6e-41
XP_016871497 (OMIM: 603736,605880,606170) PREDICTE (1781) 970 168.9 9.6e-41
XP_016871495 (OMIM: 603736,605880,606170) PREDICTE (1781) 970 168.9 9.6e-41
NP_001243397 (OMIM: 603736,605880,606170) histone (1890) 970 169.0 1e-40
XP_016871494 (OMIM: 603736,605880,606170) PREDICTE (1890) 970 169.0 1e-40
XP_005269721 (OMIM: 603736,605880,606170) PREDICTE (2073) 970 169.0 1.1e-40
XP_016871489 (OMIM: 603736,605880,606170) PREDICTE (2073) 970 169.0 1.1e-40
XP_016871491 (OMIM: 603736,605880,606170) PREDICTE (2073) 970 169.0 1.1e-40
NP_036462 (OMIM: 603736,605880,606170) histone ace (2073) 970 169.0 1.1e-40
XP_016871490 (OMIM: 603736,605880,606170) PREDICTE (2073) 970 169.0 1.1e-40
XP_016871492 (OMIM: 603736,605880,606170) PREDICTE (2073) 970 169.0 1.1e-40
XP_016871498 (OMIM: 603736,605880,606170) PREDICTE (1727) 288 58.3 1.9e-07
XP_016871493 (OMIM: 603736,605880,606170) PREDICTE (2019) 288 58.3 2.2e-07
>>NP_115564 (OMIM: 609912) histone acetyltransferase KAT (458 aa)
initn: 3114 init1: 3114 opt: 3114 Z-score: 2741.0 bits: 516.4 E(85289): 6.2e-146
Smith-Waterman score: 3114; 100.0% identity (100.0% similar) in 458 aa overlap (1-458:1-458)
10 20 30 40 50 60
pF1KB7 MAAQGAAAAVAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MAAQGAAAAVAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 YLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 YLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 KIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 YRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 YRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 YFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 YFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 YRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 YRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPK
370 380 390 400 410 420
430 440 450
pF1KB7 LVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK
::::::::::::::::::::::::::::::::::::::
NP_115 LVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK
430 440 450
>>NP_892003 (OMIM: 609912) histone acetyltransferase KAT (467 aa)
initn: 2965 init1: 2965 opt: 2966 Z-score: 2611.1 bits: 492.4 E(85289): 1.1e-138
Smith-Waterman score: 2966; 98.0% identity (98.4% similar) in 449 aa overlap (1-445:1-449)
10 20 30 40 50 60
pF1KB7 MAAQGAAAAVAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 MAAQGAAAAVAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 YLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 YLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 KNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 KIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 KIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 YRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 YRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 YFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 YFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 YRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_892 YRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPK
370 380 390 400 410 420
430 440 450
pF1KB7 LVEEHLKSAQYKKPPITVD---SVCL-KWAPPKHKQVKLSKK
::::::::::::::::: .:: .:
NP_892 LVEEHLKSAQYKKPPITGGWGAAVCRGRWGSVSIWTGRSQGLLIAVT
430 440 450 460
>>XP_011544272 (OMIM: 609912) PREDICTED: histone acetylt (300 aa)
initn: 2066 init1: 2066 opt: 2066 Z-score: 1824.4 bits: 346.2 E(85289): 7e-95
Smith-Waterman score: 2066; 100.0% identity (100.0% similar) in 300 aa overlap (159-458:1-300)
130 140 150 160 170 180
pF1KB7 ELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYE
::::::::::::::::::::::::::::::
XP_011 MDPTTAALEKEHEAITKVKYVDKIHIGNYE
10 20 30
190 200 210 220 230 240
pF1KB7 IDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISV
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB7 YEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKES
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB7 PDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWV
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB7 LLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKS
220 230 240 250 260 270
430 440 450
pF1KB7 AQYKKPPITVDSVCLKWAPPKHKQVKLSKK
::::::::::::::::::::::::::::::
XP_011 AQYKKPPITVDSVCLKWAPPKHKQVKLSKK
280 290 300
>>XP_011544273 (OMIM: 609912) PREDICTED: histone acetylt (300 aa)
initn: 2066 init1: 2066 opt: 2066 Z-score: 1824.4 bits: 346.2 E(85289): 7e-95
Smith-Waterman score: 2066; 100.0% identity (100.0% similar) in 300 aa overlap (159-458:1-300)
130 140 150 160 170 180
pF1KB7 ELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYE
::::::::::::::::::::::::::::::
XP_011 MDPTTAALEKEHEAITKVKYVDKIHIGNYE
10 20 30
190 200 210 220 230 240
pF1KB7 IDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISV
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB7 YEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKES
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB7 PDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWV
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB7 LLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKS
220 230 240 250 260 270
430 440 450
pF1KB7 AQYKKPPITVDSVCLKWAPPKHKQVKLSKK
::::::::::::::::::::::::::::::
XP_011 AQYKKPPITVDSVCLKWAPPKHKQVKLSKK
280 290 300
>>NP_001186087 (OMIM: 609880) histone acetyltransferase (442 aa)
initn: 1143 init1: 924 opt: 1164 Z-score: 1031.0 bits: 200.0 E(85289): 1.1e-50
Smith-Waterman score: 1165; 45.5% identity (70.0% similar) in 404 aa overlap (64-449:38-440)
40 50 60 70 80 90
pF1KB7 TAPSPGRVSPPTPARGEPEVTVEIGETYLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHY
: : ::.. :: . :..: .
NP_001 AGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQGHLTGKHERHFSI
10 20 30 40 50 60
100 110 120 130 140
pF1KB7 VGFNRRLDEWVDKNRLALTKTV--KDAVQKNSEKYLSELA-EQPERKITRNQ---KRKHD
: . .:. . . . :. : . .: : :. :: :. . . : . ..
NP_001 SGCPLYHNLSADECKAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREP
70 80 90 100 110 120
150 160 170 180 190
pF1KB7 EINHVQKTYAEMDPTTAALEKEHEAITKVK----------YVDKIHIGNYEIDAWYFSPF
.... . : ..: : . : . :.. .. : .: ::.:.:: ::.
NP_001 LLENLTSEY-DLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPY
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB7 PEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHK
::.:.. .:..::.:::::: . : :...: :..::: :::::..:::.::::: .:
NP_001 PEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNK
190 200 210 220 230 240
260 270 280 290 300 310
pF1KB7 IYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACI
::::::::::::::::::::.:::::.::..::.: : :..:::::::.: . ::.::
NP_001 IYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCI
250 260 270 280 290 300
320 330 340 350 360 370
pF1KB7 LTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFR
::.: :.:.::::.:: ::: :::.: :::::.:::::: .::::::. :::. :..:.
NP_001 LTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQ
310 320 330 340 350 360
380 390 400 410 420 430
pF1KB7 GT-LSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHL-KSAQYKKPP
: .:::..:: :... ::.::::.:.:.:::::.:.. :..: . : :. ..
NP_001 GKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSN
370 380 390 400 410 420
440 450
pF1KB7 ITVDSVCLKWAPPKHKQVKLSKK
:.: ::::.:::
NP_001 KTMDPSCLKWTPPKGT
430 440
>>NP_001186085 (OMIM: 609880) histone acetyltransferase (472 aa)
initn: 1121 init1: 924 opt: 1164 Z-score: 1030.6 bits: 200.0 E(85289): 1.2e-50
Smith-Waterman score: 1165; 46.7% identity (70.1% similar) in 398 aa overlap (77-449:86-470)
50 60 70 80 90 100
pF1KB7 ARGEPEVTVEIGETYLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDK
::: :.. .:.. : : : :.
NP_001 HLTGKHERHFSISGCPLYHNLSADECKVRAQSR--DKQIEERMLSH------RQD---DN
60 70 80 90 100
110 120 130 140 150 160
pF1KB7 NRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAAL
:: : . . : .. ..:: .. . ....::.:. : : : .: :
NP_001 NRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYME--HRQTYGNTREPLLENL
110 120 130 140 150 160
170 180 190 200
pF1KB7 EKEH-------------EAITKVK----------YVDKIHIGNYEIDAWYFSPFPEDYGK
.:. : . :.. .. : .: ::.:.:: ::.::.:..
NP_001 TSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYAR
170 180 190 200 210 220
210 220 230 240 250 260
pF1KB7 QPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNL
.:..::.:::::: . : :...: :..::: :::::..:::.::::: .:::::::
NP_001 LGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNL
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB7 CLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPY
::::::::::::::.:::::.::..::.: : :..:::::::.: . ::.::::.: :
NP_001 CLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQY
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB7 QRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRGT-LSI
.:.::::.:: ::: :::.: :::::.:::::: .::::::. :::. :..:.: .::
NP_001 MRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISI
350 360 370 380 390 400
390 400 410 420 430 440
pF1KB7 KDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHL-KSAQYKKPPITVDSV
:..:: :... ::.::::.:.:.:::::.:.. :..: . : :. .. :.:
NP_001 KEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPS
410 420 430 440 450 460
450
pF1KB7 CLKWAPPKHKQVKLSKK
::::.:::
NP_001 CLKWTPPKGT
470
>>NP_001186086 (OMIM: 609880) histone acetyltransferase (501 aa)
initn: 1121 init1: 924 opt: 1164 Z-score: 1030.2 bits: 200.0 E(85289): 1.2e-50
Smith-Waterman score: 1164; 48.0% identity (75.3% similar) in 356 aa overlap (96-449:150-499)
70 80 90 100 110 120
pF1KB7 PDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQKNSEK
..... : : .:.: :. ... .
NP_001 HERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQT
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB7 YLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIG
: . ...: . .: ..: .. ... :. . :. . . ... : .:
NP_001 YGN--TREP---LLENLTSEYD-LDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFG
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB7 NYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSN
::.:.:: ::.::.:.. .:..::.:::::: . : :...: :..::: :::::..
NP_001 RYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGS
240 250 260 270 280 290
250 260 270 280 290 300
pF1KB7 ISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKE
:::.::::: .:::::::::::::::::::::.:::::.::..::.: : :..::::::
NP_001 ISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKE
300 310 320 330 340 350
310 320 330 340 350 360
pF1KB7 KESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYW
:.: . ::.::::.: :.:.::::.:: ::: :::.: :::::.:::::: .::::::
NP_001 KNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYW
360 370 380 390 400 410
370 380 390 400 410 420
pF1KB7 SWVLLEILRDFRGT-LSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEE
. :::. :..:.: .:::..:: :... ::.::::.:.:.:::::.:.. :..:
NP_001 KEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDE
420 430 440 450 460 470
430 440 450
pF1KB7 HL-KSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK
. : :. .. :.: ::::.:::
NP_001 WIAKEAKRSNSNKTMDPSCLKWTPPKGT
480 490 500
>>NP_001186084 (OMIM: 609880) histone acetyltransferase (581 aa)
initn: 1121 init1: 924 opt: 1164 Z-score: 1029.3 bits: 200.1 E(85289): 1.4e-50
Smith-Waterman score: 1164; 48.0% identity (75.3% similar) in 356 aa overlap (96-449:230-579)
70 80 90 100 110 120
pF1KB7 PDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQKNSEK
..... : : .:.: :. ... .
NP_001 HERHFSISGCPLYHNLSADECKAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQT
200 210 220 230 240 250
130 140 150 160 170 180
pF1KB7 YLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIG
: . ...: . .: ..: .. ... :. . :. . . ... : .:
NP_001 YGN--TREP---LLENLTSEYD-LDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFG
260 270 280 290 300 310
190 200 210 220 230 240
pF1KB7 NYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSN
::.:.:: ::.::.:.. .:..::.:::::: . : :...: :..::: :::::..
NP_001 RYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGS
320 330 340 350 360 370
250 260 270 280 290 300
pF1KB7 ISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKE
:::.::::: .:::::::::::::::::::::.:::::.::..::.: : :..::::::
NP_001 ISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKE
380 390 400 410 420 430
310 320 330 340 350 360
pF1KB7 KESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYW
:.: . ::.::::.: :.:.::::.:: ::: :::.: :::::.:::::: .::::::
NP_001 KNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYW
440 450 460 470 480 490
370 380 390 400 410 420
pF1KB7 SWVLLEILRDFRGT-LSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEE
. :::. :..:.: .:::..:: :... ::.::::.:.:.:::::.:.. :..:
NP_001 KEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDE
500 510 520 530 540 550
430 440 450
pF1KB7 HL-KSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK
. : :. .. :.: ::::.:::
NP_001 WIAKEAKRSNSNKTMDPSCLKWTPPKGT
560 570 580
>>NP_008998 (OMIM: 609880) histone acetyltransferase KAT (611 aa)
initn: 1121 init1: 924 opt: 1164 Z-score: 1029.0 bits: 200.1 E(85289): 1.4e-50
Smith-Waterman score: 1165; 46.7% identity (70.1% similar) in 398 aa overlap (77-449:225-609)
50 60 70 80 90 100
pF1KB7 ARGEPEVTVEIGETYLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDK
::: :.. .:.. : : : :.
NP_008 HLTGKHERHFSISGCPLYHNLSADECKVRAQSR--DKQIEERMLSH------RQD---DN
200 210 220 230 240
110 120 130 140 150 160
pF1KB7 NRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAAL
:: : . . : .. ..:: .. . ....::.:. : : : .: :
NP_008 NRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYME--HRQTYGNTREPLLENL
250 260 270 280 290 300
170 180 190 200
pF1KB7 EKEH-------------EAITKVK----------YVDKIHIGNYEIDAWYFSPFPEDYGK
.:. : . :.. .. : .: ::.:.:: ::.::.:..
NP_008 TSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYAR
310 320 330 340 350 360
210 220 230 240 250 260
pF1KB7 QPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNL
.:..::.:::::: . : :...: :..::: :::::..:::.::::: .:::::::
NP_008 LGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNL
370 380 390 400 410 420
270 280 290 300 310 320
pF1KB7 CLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPY
::::::::::::::.:::::.::..::.: : :..:::::::.: . ::.::::.: :
NP_008 CLLAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQY
430 440 450 460 470 480
330 340 350 360 370 380
pF1KB7 QRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRGT-LSI
.:.::::.:: ::: :::.: :::::.:::::: .::::::. :::. :..:.: .::
NP_008 MRQGYGKMLIDFSYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISI
490 500 510 520 530 540
390 400 410 420 430 440
pF1KB7 KDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHL-KSAQYKKPPITVDSV
:..:: :... ::.::::.:.:.:::::.:.. :..: . : :. .. :.:
NP_008 KEISQETAVNPVDIVSTLQALQMLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPS
550 560 570 580 590 600
450
pF1KB7 CLKWAPPKHKQVKLSKK
::::.:::
NP_008 CLKWTPPKGT
610
>>XP_011522537 (OMIM: 609880) PREDICTED: histone acetylt (328 aa)
initn: 1143 init1: 924 opt: 1153 Z-score: 1023.1 bits: 198.1 E(85289): 3e-50
Smith-Waterman score: 1153; 52.2% identity (78.0% similar) in 314 aa overlap (138-449:14-326)
110 120 130 140 150 160
pF1KB7 RLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALE
. .: ..: .. ... :. . :.
XP_011 MEHRQTYGNTREPLLENLTSEYD-LDLFRRAQARASEDLEKLR
10 20 30 40
170 180 190 200 210 220
pF1KB7 KEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHL
. . ... : .: ::.:.:: ::.::.:.. .:..::.:::::: . : :.
XP_011 LQGQITEGSNMIKTIAFGRYELDTWYHSPYPEEYARLGRLYMCEFCLKYMKSQTILRRHM
50 60 70 80 90 100
230 240 250 260 270 280
pF1KB7 GQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYI
..: :..::: :::::..:::.::::: .:::::::::::::::::::::.:::::.::.
XP_011 AKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYV
110 120 130 140 150 160
290 300 310 320 330 340
pF1KB7 LTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVG
.::.: : :..:::::::.: . ::.::::.: :.:.::::.:: ::: :::.: ::
XP_011 MTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDFSYLLSKVEEKVG
170 180 190 200 210 220
350 360 370 380 390 400
pF1KB7 SPEKPLSDLGKLSYRSYWSWVLLEILRDFRGT-LSIKDLSQMTSITQNDIISTLQSLNMV
:::.:::::: .::::::. :::. :..:.: .:::..:: :... ::.::::.:.:.
XP_011 SPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQML
230 240 250 260 270 280
410 420 430 440 450
pF1KB7 KYWKGQHVICVTPKLVEEHL-KSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK
:::::.:.. :..: . : :. .. :.: ::::.:::
XP_011 KYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
290 300 310 320
458 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:26:17 2016 done: Fri Nov 4 09:26:18 2016
Total Scan time: 5.540 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]