Result of FASTA (omim) for
pF1KB7748
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7748, 488 aa
1>>>pF1KB7748 488 - 488 aa - 488 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.1280+/-0.000407; mu= -5.2710+/- 0.026
mean_var=415.9837+/-85.150, 0's: 0 Z-trim(124.4): 101 B-trim: 2006 in 1/56
Lambda= 0.062883
statistics sampled from 45792 (45944) to 45792 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.812), E-opt: 0.2 (0.539), width: 16
Scan time: 12.520
The best scores are: opt bits E(85289)
NP_068777 (OMIM: 142995) H2.0-like homeobox protei ( 488) 3272 310.7 6.2e-84
NP_002720 (OMIM: 604420) hematopoietically-express ( 270) 326 43.1 0.0012
XP_011541345 (OMIM: 604823) PREDICTED: homeobox pr ( 233) 297 40.4 0.0065
NP_003649 (OMIM: 604823) homeobox protein BarH-lik ( 279) 298 40.6 0.0069
>>NP_068777 (OMIM: 142995) H2.0-like homeobox protein [H (488 aa)
initn: 3272 init1: 3272 opt: 3272 Z-score: 1627.9 bits: 310.7 E(85289): 6.2e-84
Smith-Waterman score: 3272; 100.0% identity (100.0% similar) in 488 aa overlap (1-488:1-488)
10 20 30 40 50 60
pF1KB7 MFAAGLAPFYASNFSLWSAAYCSSAGPGGCSFPLDPAAVKKPSFCIADILHAGVGDLGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MFAAGLAPFYASNFSLWSAAYCSSAGPGGCSFPLDPAAVKKPSFCIADILHAGVGDLGAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PEGLAGASAAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PEGLAGASAAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 HHHPQQQQQQQQPQQQQPPPPPRAGALQPPASGTRVVPNPHHSGSAPAPSSKDLKFGIDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 HHHPQQQQQQQQPQQQQPPPPPRAGALQPPASGTRVVPNPHHSGSAPAPSSKDLKFGIDR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 ILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFASLDPINEASAILSPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFASLDPINEASAILSPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 NSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 NSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 VTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAPAADG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 VTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAPAADG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLHQTTVIKAPVTGALITASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 EQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLHQTTVIKAPVTGALITASS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 AGSGGSSGGGGNSFSFSSASSLSSSSTSAGCASSLGGGGASELLPATQPTASSAPKSPEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 AGSGGSSGGGGNSFSFSSASSLSSSSTSAGCASSLGGGGASELLPATQPTASSAPKSPEP
430 440 450 460 470 480
pF1KB7 AQGALGCL
::::::::
NP_068 AQGALGCL
>>NP_002720 (OMIM: 604420) hematopoietically-expressed h (270 aa)
initn: 306 init1: 252 opt: 326 Z-score: 186.7 bits: 43.1 E(85289): 0.0012
Smith-Waterman score: 326; 31.4% identity (54.8% similar) in 283 aa overlap (136-406:2-260)
110 120 130 140 150 160
pF1KB7 AGFPQRLSPLSAAYHHHHPQQQQQQQQPQQQQPPPPPRAGALQPPASGTRVVPNPHHSGS
: : : : :::. : .:.: . .
NP_002 MQYPHPGPAAGAVGVPL----YAPTPLLQPA
10 20
170 180 190 200 210
pF1KB7 APAPSSKDLKFGIDRILS---AEFDPKVKEGNTLRDLTSLLTGGR-----PAGVHLSGLQ
:.: : :. ::. : : . ..:::.. : :. .: . .
NP_002 HPTP------FYIEDILGRGPAAPTPAPTLPSPNSSFTSLVSPYRTPVYEPTPIHPAFSH
30 40 50 60 70 80
220 230 240 250 260 270
pF1KB7 PSAGQFFASLDPINEASAILSPLNSNPR--NSVQHQFQDTFPGPYAVLTKDTMPQTYKRK
::. . :. : ... .:: :: :. : . : .: . . : .:
NP_002 HSAAALAAAYGP----GGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFL-QRPLHK
90 100 110 120 130
280 290 300 310 320 330
pF1KB7 RSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSK
:. ... ::: : :::.:: :::.. :.::.:: :: :.. :::.:::::: :::. :
NP_002 RKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLK
140 150 160 170 180 190
340 350 360 370 380 390
pF1KB7 EAQAQKDKDKEAGEKPSGGAPAADGEQDERSPSRSEGEAESESSDSESLDMAPSDTE--R
. . :..: .: . :. :.:. :: . .. : :: . . .:.. : .
NP_002 QENPQSNKKEEL--------ESLDSSCDQRQDLPSE-QNKGASLDSSQCSPSPASQEDLE
200 210 220 230 240
400 410 420 430 440 450
pF1KB7 TEGSERSLHQTTVIKAPVTGALITASSAGSGGSSGGGGNSFSFSSASSLSSSSTSAGCAS
.: :: : ... .
NP_002 SEISEDSDQEVDIEGDKSYFNAG
250 260 270
>>XP_011541345 (OMIM: 604823) PREDICTED: homeobox protei (233 aa)
initn: 237 init1: 237 opt: 297 Z-score: 173.3 bits: 40.4 E(85289): 0.0065
Smith-Waterman score: 297; 36.9% identity (68.5% similar) in 130 aa overlap (257-382:65-194)
230 240 250 260 270 280
pF1KB7 LDPINEASAILSPLNSNPRNSVQHQFQDTFPGPYAVLTKDT---MPQTYKRKRSWSRAVF
:: :. .... .: ..: ::..:
XP_011 TVISHLVPATPGIAQALSCHQVTEAVSAEAPGGEALASSESETEQPTPRQKKPRRSRTIF
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB7 SNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDK
..:: ::::.:. :::.. ::: .:: ::::. :::.:.:::::::.. .:.
XP_011 TELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAP
100 110 120 130 140 150
350 360 370 380 390 400
pF1KB7 DKEAGEKPSGGAPAADG-EQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLH
: :. ... :... : .:. :...:. . : :...
XP_011 TKPKGRPKKNSIPTSEEIEAEEKMNSQAQGQEQLEPSQGQEELCEAQEPKARDVPLEMAE
160 170 180 190 200 210
410 420 430 440 450 460
pF1KB7 QTTVIKAPVTGALITASSAGSGGSSGGGGNSFSFSSASSLSSSSTSAGCASSLGGGGASE
XP_011 PPDPPQELPIPSSEPPPLS
220 230
>>NP_003649 (OMIM: 604823) homeobox protein BarH-like 2 (279 aa)
initn: 237 init1: 237 opt: 298 Z-score: 172.8 bits: 40.6 E(85289): 0.0069
Smith-Waterman score: 322; 30.7% identity (58.0% similar) in 231 aa overlap (164-382:13-240)
140 150 160 170 180 190
pF1KB7 QQQQPPPPPRAGALQPPASGTRVVPNPHHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEG
:. : . : ::.::: : ..
NP_003 MHCHAELRLSSPGQLKAARRRYKTFMIDEILSKETCDYFEKL
10 20 30 40
200 210 220 230 240
pF1KB7 NTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFASLDPINEASAILSPLNSNPRNSVQ----
. ::.. :: .: .:: . . :. :.. ...: : . .:
NP_003 SLYSVCPSLVV--RPKPLHSCTGSPSL-RAYPLLSVITRQPTVISHLVPATPGIAQALSC
50 60 70 80 90
250 260 270 280 290 300
pF1KB7 HQFQDTF----PGPYAVLTKDT---MPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVT
:: .. :: :. .... .: ..: ::..:..:: ::::.:. :::..
NP_003 HQVTEAVSAEAPGGEALASSESETEQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLS
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB7 KPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAPAADG-E
::: .:: ::::. :::.:.:::::::.. .:. : :. ... :... :
NP_003 TPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQEAPTKPKGRPKKNSIPTSEEIE
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB7 QDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLHQTTVIKAPVTGALITASSA
.:. :...:. . : :...
NP_003 AEEKMNSQAQGQEQLEPSQGQEELCEAQEPKARDVPLEMAEPPDPPQELPIPSSEPPPLS
220 230 240 250 260 270
488 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:09:34 2016 done: Fri Nov 4 22:09:36 2016
Total Scan time: 12.520 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]