Result of FASTA (ccds) for
pF1KB7706
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7706, 465 aa
1>>>pF1KB7706 465 - 465 aa - 465 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.1513+/-0.00103; mu= -1.7620+/- 0.063
mean_var=323.2670+/-65.240, 0's: 0 Z-trim(114.5): 14 B-trim: 109 in 1/53
Lambda= 0.071334
statistics sampled from 15012 (15025) to 15012 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.462), width: 16
Scan time: 3.420
The best scores are: opt bits E(32554)
CCDS75308.1 SMAD5 gene_id:4090|Hs108|chr5 ( 465) 3271 350.1 2.9e-96
CCDS3765.1 SMAD1 gene_id:4086|Hs108|chr4 ( 465) 2926 314.6 1.4e-85
CCDS45032.1 SMAD9 gene_id:4093|Hs108|chr13 ( 467) 2584 279.4 5.7e-75
CCDS11934.1 SMAD2 gene_id:4087|Hs108|chr18 ( 467) 1402 157.7 2.3e-38
CCDS9360.1 SMAD9 gene_id:4093|Hs108|chr13 ( 430) 1346 151.9 1.2e-36
CCDS53950.1 SMAD3 gene_id:4088|Hs108|chr15 ( 320) 1218 138.6 9e-33
CCDS45288.1 SMAD3 gene_id:4088|Hs108|chr15 ( 381) 1218 138.7 1e-32
CCDS10222.1 SMAD3 gene_id:4088|Hs108|chr15 ( 425) 1218 138.7 1.1e-32
CCDS53951.1 SMAD3 gene_id:4088|Hs108|chr15 ( 230) 1151 131.6 8.4e-31
>>CCDS75308.1 SMAD5 gene_id:4090|Hs108|chr5 (465 aa)
initn: 3271 init1: 3271 opt: 3271 Z-score: 1841.6 bits: 350.1 E(32554): 2.9e-96
Smith-Waterman score: 3271; 100.0% identity (100.0% similar) in 465 aa overlap (1-465:1-465)
10 20 30 40 50 60
pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 NNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 MDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 MDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 DPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 NFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS75 NFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGW
370 380 390 400 410 420
430 440 450 460
pF1KB7 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS
:::::::::::::::::::::::::::::::::::::::::::::
CCDS75 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS
430 440 450 460
>>CCDS3765.1 SMAD1 gene_id:4086|Hs108|chr4 (465 aa)
initn: 2687 init1: 1430 opt: 2926 Z-score: 1649.7 bits: 314.6 E(32554): 1.4e-85
Smith-Waterman score: 2926; 89.7% identity (95.1% similar) in 465 aa overlap (3-465:2-465)
10 20 30 40 50 60
pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPG
...:::::::::::::::::::::::::::::::::::::::::::::::::::: ::
CCDS37 MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPG
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKE
:::.:::::::::::::::::::::::::::::::::::::::::::. :::::::::::
CCDS37 QPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 VCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQP
::::::::::::::::::::::::.:.:::::::.:::::..:::::: ::::::::.::
CCDS37 VCINPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQP
120 130 140 150 160 170
190 200 210 220 230
pF1KB7 NNTPFPLSPNSPYPPSP--ASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNS
:. ::: :::: :: :: .:::::.::.:: ::::::.:::::::::.::.: : ::.:
CCDS37 NSHPFPHSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMPADTPPPAYLPPEDPMTQDGS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 QPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG
::::: : : : . :. ::: ::::::::::::::::::::::::::::::::::::
CCDS37 QPMDT-NMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 FTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS37 FTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB7 NCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVK
:::.::::::::::::::.::::::::::::::::::::::::.::::::::::::::::
CCDS37 NCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVK
360 370 380 390 400 410
420 430 440 450 460
pF1KB7 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS
::::::::::::::::::::::::::::::::::::::: :::::::
CCDS37 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
420 430 440 450 460
>>CCDS45032.1 SMAD9 gene_id:4093|Hs108|chr13 (467 aa)
initn: 2563 init1: 1333 opt: 2584 Z-score: 1459.5 bits: 279.4 E(32554): 5.7e-75
Smith-Waterman score: 2584; 78.8% identity (91.0% similar) in 466 aa overlap (2-465:5-467)
10 20 30 40 50
pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALS
: ..:::::::::::::::::::::::::::::::.::::::::::::.:::.:::
CCDS45 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 SPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSK
:::::::::::::::::::::::::::::::::::::::::::::::::. ::::::::
CCDS45 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 QKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLS-HNEPHMPQNATFPDS
:::::::::::.:::.:::::::::::.:.::: :::..::. : :.:: ::.:::.:::
CCDS45 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 FHQPNNTPFPLSPNSPYPPSPASSTYPNSPAS-SGPGSPFQLPADTPPPAYMPPDDQMGQ
:.:: . .: ::. . :: ...::.::.: : : ::.: .:::: : . . :
CCDS45 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 DNSQPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVL
..::.:.. . ... :: . : .:: ::::.::::..::::::::::.:.::: :::
CCDS45 -SGQPVDATADR--HVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVL
250 260 270 280 290
300 310 320 330 340 350
pF1KB7 VDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFV
.:::::::::..::::::::::::::::::::::::::::::::::::::::.:::::::
CCDS45 IDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFV
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB7 QSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMS
::::::..:::::.:::::::.::::.:::: :::::::::.::::.:::::::::::::
CCDS45 QSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMS
360 370 380 390 400 410
420 430 440 450 460
pF1KB7 FVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS
:::::::::::::::::::::::::::::::::::::::::: :::::::
CCDS45 FVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
420 430 440 450 460
>>CCDS11934.1 SMAD2 gene_id:4087|Hs108|chr18 (467 aa)
initn: 1577 init1: 902 opt: 1402 Z-score: 802.1 bits: 157.7 E(32554): 2.3e-38
Smith-Waterman score: 1794; 56.6% identity (71.9% similar) in 509 aa overlap (4-465:1-467)
10 20 30 40
pF1KB7 MTSMASLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDALVKKLKKKKG
:.:.. :: :.:::::::: :. .:::: :::: .::::::: :
CCDS11 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-G
10 20 30 40 50
50 60 70
pF1KB7 AMEELEKALSSPGQPSKCVTIP------------------------------RSLDGRLQ
..:::::... . .:::::: ::::::::
CCDS11 RLDELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQ
60 70 80 90 100 110
80 90 100 110 120 130
pF1KB7 VSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLP
::::::::::::::.::::::.:::::: .. ::. :. :. :::.:::::.:::.::::
CCDS11 VSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLP
120 130 140 150 160 170
140 150 160 170 180 190
pF1KB7 PVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNTPFPLSPNSPYPPSP
:::::::.: .:... :. .:.:..:: . . :.: : :
CCDS11 PVLVPRHTE------ILTELPPLDDYTHSIPENTNFPAG----------IEPQSNYIP--
180 190 200 210
200 210 220 230 240 250
pF1KB7 ASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMG-QDNSQPMDTSN--NMIPQIM-P
.::::.:. : . . :. .: :::.. .. : . :
CCDS11 ----------------------ETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSP
220 230 240 250
260 270 280 290 300 310
pF1KB7 SISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKSRFCLGL
: :.:::.: :: ::::.:::::.::::.::::. :. :::::::::.. ::::::
CCDS11 VNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSE-RFCLGL
260 270 280 290 300 310
320 330 340 350 360 370
pF1KB7 LSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCK
:::::::.:.: ::::::.::.:::.::::.:::::::.::::: ::: ..:.::.::::
CCDS11 LSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCK
320 330 340 350 360 370
380 390 400 410 420 430
pF1KB7 IPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTP
:: .:.:::::::::: :::::::.::::::.::.::::::::::::::::.:: :::::
CCDS11 IPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTP
380 390 400 410 420 430
440 450 460
pF1KB7 CWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS
::::.::.:::::::::::::::: ::.:
CCDS11 CWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS
440 450 460
>>CCDS9360.1 SMAD9 gene_id:4093|Hs108|chr13 (430 aa)
initn: 2380 init1: 1324 opt: 1346 Z-score: 771.4 bits: 151.9 E(32554): 1.2e-36
Smith-Waterman score: 2449; 76.4% identity (85.8% similar) in 466 aa overlap (2-465:5-430)
10 20 30 40 50
pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALS
: ..:::::::::::::::::::::::::::::::.::::::::::::.:::.:::
CCDS93 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 SPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSK
:::::::::::::::::::::::::::::::::::::::::::::::::. ::::::::
CCDS93 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 QKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLS-HNEPHMPQNATFPDS
:::::::::::.:::.:::::::::::.:.::: :::..::. : :.:: ::.:::.:::
CCDS93 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 FHQPNNTPFPLSPNSPYPPSPASSTYPNSPAS-SGPGSPFQLPADTPPPAYMPPDDQMGQ
:.:: . .: ::. . :: ...::.::.: : : ::.:
CCDS93 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQ-------------------
190 200 210 220
240 250 260 270 280 290
pF1KB7 DNSQPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVL
: .:: ::::.::::..::::::::::.:.::: :::
CCDS93 ---------------------HSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVL
230 240 250 260
300 310 320 330 340 350
pF1KB7 VDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFV
.:::::::::..::::::::::::::::::::::::::::::::::::::::.:::::::
CCDS93 IDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFV
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB7 QSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMS
::::::..:::::.:::::::.::::.:::: :::::::::.::::.:::::::::::::
CCDS93 QSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMS
330 340 350 360 370 380
420 430 440 450 460
pF1KB7 FVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS
:::::::::::::::::::::::::::::::::::::::::: :::::::
CCDS93 FVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
390 400 410 420 430
>>CCDS53950.1 SMAD3 gene_id:4088|Hs108|chr15 (320 aa)
initn: 1156 init1: 904 opt: 1218 Z-score: 701.9 bits: 138.6 E(32554): 9e-33
Smith-Waterman score: 1373; 58.6% identity (76.5% similar) in 362 aa overlap (107-465:1-320)
80 90 100 110 120 130
pF1KB7 QVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVL
...::: :. :. :::.:::::.:::.:::
CCDS53 MELCEFAFNMKKDEVCVNPYHYQRVETPVL
10 20 30
140 150 160 170 180 190
pF1KB7 PPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSFHQPNNTPFPLSPNSPYPPS
::::::::.:. . : .. ::. .:.:..:: ... .: :
CCDS53 PPVLVPRHTEIPAEFPPLDDY---SHS---IPENTNFPAGIEPQSNIP------------
40 50 60 70
200 210 220 230 240 250
pF1KB7 PASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN-SQPMDT-SNNMIPQIM-P
.::::.:. : . .. . .. ::. : :. :. : :
CCDS53 -----------------------ETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSP
80 90 100
260 270 280 290 300 310
pF1KB7 SISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKSRFCLGL
. .. :.:::.: :: :::: :::::.::::.::::. :. :::::::::.. ::::::
CCDS53 AHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGL
110 120 130 140 150 160
320 330 340 350 360 370
pF1KB7 LSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCK
:::::::...: ::::::.::.:::.::::.:::::::.::::: ::: ..:.::.::::
CCDS53 LSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCK
170 180 190 200 210 220
380 390 400 410 420 430
pF1KB7 IPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTP
:: .:.:::::::::: :::::::.::::::.::.::::::::::::::::.:: :::::
CCDS53 IPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTP
230 240 250 260 270 280
440 450 460
pF1KB7 CWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS
::::.::.:::::::::::::::: ::::
CCDS53 CWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS
290 300 310 320
>>CCDS45288.1 SMAD3 gene_id:4088|Hs108|chr15 (381 aa)
initn: 1412 init1: 904 opt: 1218 Z-score: 700.9 bits: 138.7 E(32554): 1e-32
Smith-Waterman score: 1629; 61.4% identity (78.4% similar) in 399 aa overlap (70-465:25-381)
40 50 60 70 80 90
pF1KB7 KKLKKKKGAMEELEKALSSPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQ
::::::::::::::::::::::.::::::.
CCDS45 MSCLHPRQTWKGAALVHRKAWWMGRSLDGRLQVSHRKGLPHVIYCRLWRWPDLH
10 20 30 40 50
100 110 120 130 140 150
pF1KB7 SHHELKPLDICEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRN
:::::. ...::: :. :. :::.:::::.:::.:::::::::::.:. . : ..
CCDS45 SHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDY--
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB7 LSHNEPHMPQNATFPDSFHQPNNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPA
::. .:.:..:: ... .: :
CCDS45 -SHS---IPENTNFPAGIEPQSNIP-----------------------------------
120 130
220 230 240 250 260 270
pF1KB7 DTPPPAYMPPDDQMGQDN-SQPMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVY
.::::.:. : . .. . .. ::. : :. :. : :. .. :.:::.: :: :::: :
CCDS45 ETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISY
140 150 160 170 180 190
280 290 300 310 320 330
pF1KB7 YELNNRVGEAFHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHL
::::.::::.::::. :. :::::::::.. :::::::::::::...: ::::::.::.:
CCDS45 YELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRL
200 210 220 230 240 250
340 350 360 370 380 390
pF1KB7 YYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSV
::.::::.:::::::.::::: ::: ..:.::.:::::: .:.:::::::::: ::::::
CCDS45 YYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSV
260 270 280 290 300 310
400 410 420 430 440 450
pF1KB7 NHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGS
:.::::::.::.::::::::::::::::.:: :::::::::.::.:::::::::::::::
CCDS45 NQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGS
320 330 340 350 360 370
460
pF1KB7 PLNPISSVS
: ::::
CCDS45 PSIRCSSVS
380
>>CCDS10222.1 SMAD3 gene_id:4088|Hs108|chr15 (425 aa)
initn: 1508 init1: 904 opt: 1218 Z-score: 700.3 bits: 138.7 E(32554): 1.1e-32
Smith-Waterman score: 1885; 60.9% identity (78.6% similar) in 468 aa overlap (4-465:1-425)
10 20 30 40 50
pF1KB7 MTSMASLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALS
:.:.. :: : ::::::::.:.. :::: :::: .::::::: : ..:::::..
CCDS10 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAIT
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 SPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSK
. . .::.:::::::::::::::::::::::::.::::::.:::::. ...::: :. :
CCDS10 TQNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 QKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATFPDSF
. :::.:::::.:::.:::::::::::.:. . : .. ::. .:.:..:: ..
CCDS10 KDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDY---SHS---IPENTNFPAGI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 HQPNNTPFPLSPNSPYPPSPASSTYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDN
. .: : .::::.:. : . .. .
CCDS10 EPQSNIP-----------------------------------ETPPPGYLSEDGETSDHQ
180 190
240 250 260 270 280 290
pF1KB7 -SQPMDT-SNNMIPQIM-PSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSV
.. ::. : :. :. : :. .. :.:::.: :: :::: :::::.::::.::::. :.
CCDS10 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSM
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB7 LVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIF
:::::::::.. :::::::::::::...: ::::::.::.:::.::::.:::::::.::
CCDS10 TVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIF
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB7 VQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRM
::: ::: ..:.::.:::::: .:.:::::::::: :::::::.::::::.::.::::::
CCDS10 VQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRM
320 330 340 350 360 370
420 430 440 450 460
pF1KB7 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS
::::::::::.:: :::::::::.::.:::::::::::::::: ::::
CCDS10 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS
380 390 400 410 420
>>CCDS53951.1 SMAD3 gene_id:4088|Hs108|chr15 (230 aa)
initn: 939 init1: 904 opt: 1151 Z-score: 666.5 bits: 131.6 E(32554): 8.4e-31
Smith-Waterman score: 1151; 73.5% identity (89.1% similar) in 230 aa overlap (238-465:2-230)
210 220 230 240 250 260
pF1KB7 SSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDT-SNNMIPQIM-PSISSRDVQPVAY
.. ::. : :. :. : :. .. :.:::.:
CCDS53 MNHSMDAGSPNLSPNPMSPAHNNLDLQPVTY
10 20 30
270 280 290 300 310 320
pF1KB7 EEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIEN
:: :::: :::::.::::.::::. :. :::::::::.. :::::::::::::...:
CCDS53 CEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVEL
40 50 60 70 80 90
330 340 350 360 370 380
pF1KB7 TRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNN
::::::.::.:::.::::.:::::::.::::: ::: ..:.::.:::::: .:.::::::
CCDS53 TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNN
100 110 120 130 140 150
390 400 410 420 430 440
pF1KB7 QEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQ
:::: :::::::.::::::.::.::::::::::::::::.:: :::::::::.::.::::
CCDS53 QEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ
160 170 180 190 200 210
450 460
pF1KB7 WLDKVLTQMGSPLNPISSVS
:::::::::::: ::::
CCDS53 WLDKVLTQMGSPSIRCSSVS
220 230
465 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:04:51 2016 done: Fri Nov 4 22:04:51 2016
Total Scan time: 3.420 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]