Result of FASTA (ccds) for
pF1KB7636
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7636, 377 aa
1>>>pF1KB7636 377 - 377 aa - 377 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5147+/-0.000846; mu= 14.8682+/- 0.051
mean_var=57.2943+/-11.645, 0's: 0 Z-trim(105.1): 30 B-trim: 0 in 0/53
Lambda= 0.169441
statistics sampled from 8197 (8223) to 8197 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.253), width: 16
Scan time: 1.960
The best scores are: opt bits E(32554)
CCDS14420.1 HDAC8 gene_id:55869|Hs108|chrX ( 377) 2575 637.8 4.8e-183
CCDS55451.1 HDAC8 gene_id:55869|Hs108|chrX ( 256) 1674 417.5 6.7e-117
CCDS55449.1 HDAC8 gene_id:55869|Hs108|chrX ( 286) 1586 396.0 2.2e-110
CCDS43493.2 HDAC2 gene_id:3066|Hs108|chr6 ( 488) 1089 274.5 1.4e-73
CCDS360.1 HDAC1 gene_id:3065|Hs108|chr1 ( 482) 1083 273.1 3.7e-73
CCDS4264.1 HDAC3 gene_id:8841|Hs108|chr5 ( 428) 1048 264.5 1.3e-70
CCDS55452.1 HDAC8 gene_id:55869|Hs108|chrX ( 158) 1001 252.9 1.4e-67
CCDS55450.1 HDAC8 gene_id:55869|Hs108|chrX ( 146) 999 252.4 1.8e-67
CCDS14306.1 HDAC6 gene_id:10013|Hs108|chrX (1215) 400 106.2 1.6e-22
CCDS55448.1 HDAC8 gene_id:55869|Hs108|chrX ( 139) 364 97.2 9.4e-21
CCDS47555.1 HDAC9 gene_id:9734|Hs108|chr7 (1011) 360 96.4 1.2e-19
CCDS83163.1 HDAC9 gene_id:9734|Hs108|chr7 (1025) 360 96.4 1.2e-19
CCDS47554.1 HDAC9 gene_id:9734|Hs108|chr7 (1066) 360 96.4 1.2e-19
CCDS47553.1 HDAC9 gene_id:9734|Hs108|chr7 (1069) 360 96.4 1.3e-19
CCDS14088.1 HDAC10 gene_id:83933|Hs108|chr22 ( 669) 343 92.2 1.4e-18
CCDS45696.1 HDAC5 gene_id:10014|Hs108|chr17 (1122) 334 90.1 1.1e-17
CCDS32663.1 HDAC5 gene_id:10014|Hs108|chr17 (1123) 334 90.1 1.1e-17
CCDS2529.1 HDAC4 gene_id:9759|Hs108|chr2 (1084) 333 89.8 1.2e-17
CCDS41776.1 HDAC7 gene_id:51564|Hs108|chr12 ( 954) 327 88.3 3e-17
CCDS81685.1 HDAC7 gene_id:51564|Hs108|chr12 ( 974) 327 88.3 3.1e-17
CCDS8756.2 HDAC7 gene_id:51564|Hs108|chr12 ( 991) 327 88.3 3.1e-17
CCDS2615.1 HDAC11 gene_id:79885|Hs108|chr3 ( 347) 278 76.3 4.7e-14
CCDS46760.1 HDAC11 gene_id:79885|Hs108|chr3 ( 296) 252 69.9 3.3e-12
CCDS54545.1 HDAC10 gene_id:83933|Hs108|chr22 ( 649) 256 70.9 3.5e-12
>>CCDS14420.1 HDAC8 gene_id:55869|Hs108|chrX (377 aa)
initn: 2575 init1: 2575 opt: 2575 Z-score: 3399.8 bits: 637.8 E(32554): 4.8e-183
Smith-Waterman score: 2575; 100.0% identity (100.0% similar) in 377 aa overlap (1-377:1-377)
10 20 30 40 50 60
pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH
310 320 330 340 350 360
370
pF1KB7 RIQQILNYIKGNLKHVV
:::::::::::::::::
CCDS14 RIQQILNYIKGNLKHVV
370
>>CCDS55451.1 HDAC8 gene_id:55869|Hs108|chrX (256 aa)
initn: 1674 init1: 1674 opt: 1674 Z-score: 2212.3 bits: 417.5 E(32554): 6.7e-117
Smith-Waterman score: 1674; 100.0% identity (100.0% similar) in 245 aa overlap (1-245:1-245)
10 20 30 40 50 60
pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
:::::
CCDS55 YQICERYEPPAPNPGL
250
>>CCDS55449.1 HDAC8 gene_id:55869|Hs108|chrX (286 aa)
initn: 1586 init1: 1586 opt: 1586 Z-score: 2095.2 bits: 396.0 E(32554): 2.2e-110
Smith-Waterman score: 1748; 75.9% identity (75.9% similar) in 377 aa overlap (1-377:1-286)
10 20 30 40 50 60
pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMR-----
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
CCDS55 ------------------------------------------------------------
130 140 150 160 170 180
pF1KB7 TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
::::::::::::::::::::::::::::::::::
CCDS55 --------------------------DEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
60 70 80
190 200 210 220 230 240
pF1KB7 HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
90 100 110 120 130 140
250 260 270 280 290 300
pF1KB7 YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
150 160 170 180 190 200
310 320 330 340 350 360
pF1KB7 LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH
210 220 230 240 250 260
370
pF1KB7 RIQQILNYIKGNLKHVV
:::::::::::::::::
CCDS55 RIQQILNYIKGNLKHVV
270 280
>>CCDS43493.2 HDAC2 gene_id:3066|Hs108|chr6 (488 aa)
initn: 975 init1: 551 opt: 1089 Z-score: 1434.7 bits: 274.5 E(32554): 1.4e-73
Smith-Waterman score: 1089; 43.4% identity (77.1% similar) in 341 aa overlap (35-374:33-372)
10 20 30 40 50 60
pF1KB7 EEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASM
:.: :.:.:. :.:...:.: .:. :.
CCDS43 YSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EEMATFHTDAYLQHLQKVSQEGDDDHPDSIE-YGLGYDCPATEGIFDYAAAIGGATITAA
:::. .:.: :.. :... .. ... ... ...: :::. .:.:.. :.....:
CCDS43 EEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 QCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGD
: . .:.::.:: :::::.:::::::.:: ::.::.: . .:.::.:.:.::::
CCDS43 VKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 GVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQI
:::.:: :..:::::.::.. .::::::. :.: :::.::.:: :..:::.::.: ::
CCDS43 GVEEAFYTTDRVMTVSFHKYGE-YFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 CESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGG
. ....:.. ..:.::::: :::...:: . ::.: : .::.. . ..: :.:::
CCDS43 FKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 GGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQ
:::.. :.:::::: :.: : . .:.: ...: .:::. :.:.:: ..: :. ..
CCDS43 GGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYME
310 320 330 340 350 360
370
pF1KB7 QILNYIKGNLKHVV
.: . . ::.
CCDS43 KIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEF
370 380 390 400 410 420
>>CCDS360.1 HDAC1 gene_id:3065|Hs108|chr1 (482 aa)
initn: 949 init1: 542 opt: 1083 Z-score: 1426.9 bits: 273.1 E(32554): 3.7e-73
Smith-Waterman score: 1083; 43.1% identity (77.1% similar) in 341 aa overlap (35-374:32-371)
10 20 30 40 50 60
pF1KB7 EEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASM
:.: :.:.:. :.:...:.: .:. :.
CCDS36 AQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EEMATFHTDAYLQHLQKVSQEGDDDHPDSIE-YGLGYDCPATEGIFDYAAAIGGATITAA
:::. .:.: :.. :... .. ... ... ...: :::. .:.:.. :.....:
CCDS36 EEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVASA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 QCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGD
: . .:.::.:: :::::.:::::::.:: ::.::.: . .:.::.:.:.::::
CCDS36 VKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 GVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQI
:::.:: :..:::::.::.. .::::::. :.: :::.::.:: :..:::.::.: :
CCDS36 GVEEAFYTTDRVMTVSFHKYGE-YFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 CESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGG
. :...:.. :.:.::::: :.:...:: . ::.: : .::.... ...: :.:::
CCDS36 FKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 GGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQ
:::.. :.:::::: :.: : . .:.: ...: .:::. :.:.:: ..: . ..
CCDS36 GGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLE
310 320 330 340 350 360
370
pF1KB7 QILNYIKGNLKHVV
.: . . ::.
CCDS36 KIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEDDPDKRISICSSDKRIACEEEF
370 380 390 400 410 420
>>CCDS4264.1 HDAC3 gene_id:8841|Hs108|chr5 (428 aa)
initn: 1038 init1: 882 opt: 1048 Z-score: 1381.5 bits: 264.5 E(32554): 1.3e-70
Smith-Waterman score: 1048; 43.3% identity (75.1% similar) in 342 aa overlap (35-374:26-367)
10 20 30 40 50 60
pF1KB7 EEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASM
:.: ...:::. :.:.:.: . :: ::.
CCDS42 MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 EEMATFHTDAYLQHLQKVSQEGDDDHPDSIE-YGLGYDCPATEGIFDYAAAIGGATITAA
..: ::.. :.. ::.:: . . :.. ...: :::. :.:.. . ::.. .:
CCDS42 HDMCRFHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 QCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGD
: . .: .::::.:: ::::: :::::::.:: :.:::.: . :.::.:.:.::::
CCDS42 TQLNNKICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGD
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 GVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQI
::..:: .:..:::::.::.. :::::::. .:: .:::: .:::..:::.:..: ..
CCDS42 GVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB7 CESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGG
. :...: . ..: .::: :::... : . ::.. : :.:..:. .... :.:::
CCDS42 FQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGG
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB7 GGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCR-PDRNEPHRI
:::.. :.:::::: :.... ...: :.: :.: ..::..:. : : ..: . .
CCDS42 GGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYL
300 310 320 330 340 350
370
pF1KB7 QQILNYIKGNLKHVV
.:: . : :::
CCDS42 DQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYD
360 370 380 390 400 410
>>CCDS55452.1 HDAC8 gene_id:55869|Hs108|chrX (158 aa)
initn: 1001 init1: 1001 opt: 1001 Z-score: 1326.6 bits: 252.9 E(32554): 1.4e-67
Smith-Waterman score: 1001; 99.3% identity (100.0% similar) in 147 aa overlap (1-147:1-147)
10 20 30 40 50 60
pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
::::::::::::::::::::::::::.
CCDS55 TAAQCLIDGMCKVAINWSGGWHHAKKETCVYVALYKAF
130 140 150
>>CCDS55450.1 HDAC8 gene_id:55869|Hs108|chrX (146 aa)
initn: 999 init1: 999 opt: 999 Z-score: 1324.6 bits: 252.4 E(32554): 1.8e-67
Smith-Waterman score: 999; 100.0% identity (100.0% similar) in 146 aa overlap (1-146:1-146)
10 20 30 40 50 60
pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
::::::::::::::::::::::::::
CCDS55 TAAQCLIDGMCKVAINWSGGWHHAKK
130 140
>>CCDS14306.1 HDAC6 gene_id:10013|Hs108|chrX (1215 aa)
initn: 302 init1: 133 opt: 400 Z-score: 517.8 bits: 106.2 E(32554): 1.6e-22
Smith-Waterman score: 400; 27.6% identity (55.9% similar) in 322 aa overlap (19-324:484-800)
10 20 30 40
pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMC---DSL-AKIPKRASMVHSL
.:. .... : :: ..:.: .
CCDS14 NVEESEEEGPWEPPVLPILTWPVLQSRTGLVYDQNMMNHCNLWDSHHPEVPQRILRIMCR
460 470 480 490 500 510
50 60 70 80 90 100
pF1KB7 IEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDD-HPDSIEYGLGYDCP
.: .: . . :. :. :. : :. :. ::. . . . : .: .. : ::
CCDS14 LEELGLAGRCLTLTPRPATEAELLTCHSAEYVGHLRATEKMKTRELHRESSNFDSIYICP
520 530 540 550 560 570
110 120 130 140 150 160
pF1KB7 ATEGIFDYAAAIGGATITAAQCLIDG--MCKVAINWSGGWHHAKKDEASGFCYLNDAVLG
.: : : ::. .. ...: . .:. : :::..: : :::..:.....
CCDS14 ST---FACAQLATGAACRLVEAVLSGEVLNGAAVVRPPG-HHAEQDAACGFCFFNSVAVA
580 590 600 610 620
170 180 190 200 210
pF1KB7 ILRLRR---KFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFP--GTGDVS
. . . ::: :: :.:::.:.. : .:. ::::... : ::: : :
CCDS14 ARHAQTISGHALRILIVDWDVHHGNGTQHMFEDDPSVLYVSLHRYDHGTFFPMGDEGASS
630 640 650 660 670 680
220 230 240 250 260 270
pF1KB7 DVGLGKGRYYSVNVPIQDG--IQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDP
..: . : ..::: .: . : : . .. . :::. :... : :. :::
CCDS14 QIGRAAGTGFTVNVA-WNGPRMGDADYLAAWHRLVLPIAYEFNPELVLVSAGFDAARGDP
690 700 710 720 730 740
280 290 300 310 320 330
pF1KB7 MCSFNMTPVGIGKCLKYILQWQLATLILG-GGGYNLANTARCWTYLTGVILGKTLSSEIP
. . ...: : .. . .. . .:: :::::.. .. . : .::
CCDS14 LGGCQVSPEGYAHLTHLLMGLASGRIILILEGGYNLTSISESMAACTRSLLGDPPPLLTL
750 760 770 780 790 800
340 350 360 370
pF1KB7 DHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
CCDS14 PRPPLSGALASITETIQVHRRYWRSLRVMKVEDREGPSSSKLVTKKAPQPAKPRLAERMT
810 820 830 840 850 860
>--
initn: 184 init1: 85 opt: 364 Z-score: 470.2 bits: 97.4 E(32554): 7.2e-20
Smith-Waterman score: 364; 28.7% identity (58.3% similar) in 314 aa overlap (29-324:103-404)
10 20 30 40 50
pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVH-SLIEAYALHKQMRIV
::. . :.: .. .::. : . . .
CCDS14 GMDLNLEAEALAGTGLVLDEQLNEFHCLWDDSFPEGPERLHAIKEQLIQEGLLDRCVSF-
80 90 100 110 120 130
60 70 80 90 100
pF1KB7 KPKVASMEEMATFHTDAYLQHLQKVSQ---EGD----DDHPDSIE-YGLGYDCP--ATEG
. . : ::. :. :.. :....: ::. : ::. . .:.: :. .
CCDS14 QARFAEKEELMLVHSLEYID-LMETTQYMNEGELRVLADTYDSVYLHPNSYSCACLASGS
140 150 160 170 180 190
110 120 130 140 150 160
pF1KB7 IFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGI--LRL
.. . :. :: : .:: :: : :::... .:.:..: .... .
CCDS14 VLRLVDAVLGAEIR------NGM---AIIRPPG-HHAQHSLMDGYCMFNHVAVAARYAQQ
200 210 220 230 240
170 180 190 200 210 220
pF1KB7 RRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPG-FFPG--TGDVSDVGLGKG
.....:.: :: :.:::.:.. .:. .:. :.:.. : :.: ... : .:.:.:
CCDS14 KHRIRRVLIVDWDVHHGQGTQFTFDQDPSVLYFSIHRYEQGRFWPHLKASNWSTTGFGQG
250 260 270 280 290 300
230 240 250 260 270 280
pF1KB7 RYYSVNVPI-QDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTP
. :..::: : :..: : :: : :.:. :.. : :.. ::: . ::
CCDS14 QGYTINVPWNQVGMRDADYIAAFLHVLLPVALEFQPQLVLVAAGFDALQGDPKGEMAATP
310 320 330 340 350 360
290 300 310 320 330 340
pF1KB7 VGIGKCLKYILQWQLATLILG-GGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAY
.:... . .. . :::. ::::: :. . ..::
CCDS14 AGFAQLTHLLMGLAGGKLILSLEGGYNLRALAEGVSASLHTLLGDPCPMLESPGAPCRSA
370 380 390 400 410 420
350 360 370
pF1KB7 GPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV
CCDS14 QASVSCALEALEPFWEVLVRSTETVERDNMEEDNVEESEEEGPWEPPVLPILTWPVLQSR
430 440 450 460 470 480
>>CCDS55448.1 HDAC8 gene_id:55869|Hs108|chrX (139 aa)
initn: 634 init1: 364 opt: 364 Z-score: 486.0 bits: 97.2 E(32554): 9.4e-21
Smith-Waterman score: 611; 52.2% identity (52.2% similar) in 245 aa overlap (1-245:1-128)
10 20 30 40 50 60
pF1KB7 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMR-----
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
CCDS55 ------------------------------------------------------------
130 140 150 160 170 180
pF1KB7 TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
::::::::::::::::::::::::::::::::::
CCDS55 --------------------------DEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
60 70 80
190 200 210 220 230 240
pF1KB7 HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
:::: ::::::::::::::::::::::::::::::
CCDS55 HGDG--------------------------TGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
90 100 110 120
250 260 270 280 290 300
pF1KB7 YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
:::::
CCDS55 YQICERYEPPAPNPGL
130
377 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:31:01 2016 done: Fri Nov 4 12:31:01 2016
Total Scan time: 1.960 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]