Result of FASTA (omim) for
pF1KB7607
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7607, 299 aa
1>>>pF1KB7607 299 - 299 aa - 299 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.0634+/-0.000398; mu= -8.1272+/- 0.025
mean_var=418.3074+/-84.059, 0's: 0 Z-trim(124.2): 147 B-trim: 20 in 1/55
Lambda= 0.062709
statistics sampled from 45306 (45500) to 45306 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.827), E-opt: 0.2 (0.533), width: 16
Scan time: 9.270
The best scores are: opt bits E(85289)
NP_000545 (OMIM: 120970,268000,602225,613829) cone ( 299) 2047 198.4 1.4e-50
NP_001257452 (OMIM: 600037,610125,613986) homeobox ( 289) 590 66.6 6.7e-11
NP_001257453 (OMIM: 600037,610125,613986) homeobox ( 289) 590 66.6 6.7e-11
NP_758840 (OMIM: 600037,610125,613986) homeobox pr ( 289) 590 66.6 6.7e-11
NP_001186699 (OMIM: 600036) homeobox protein OTX1 ( 354) 572 65.0 2.4e-10
NP_055377 (OMIM: 600036) homeobox protein OTX1 [Ho ( 354) 572 65.0 2.4e-10
NP_068374 (OMIM: 600037,610125,613986) homeobox pr ( 297) 564 64.2 3.5e-10
NP_001257454 (OMIM: 600037,610125,613986) homeobox ( 297) 564 64.2 3.5e-10
NP_001012677 (OMIM: 611164) arginine-fifty homeobo ( 315) 483 56.9 5.8e-08
NP_005160 (OMIM: 602078,602753) paired mesoderm ho ( 284) 383 47.8 2.9e-05
NP_003915 (OMIM: 209880,603851,613013) paired meso ( 314) 379 47.5 4e-05
XP_011538970 (OMIM: 607410) PREDICTED: diencephalo ( 377) 358 45.7 0.00017
NP_757379 (OMIM: 607410) diencephalon/mesencephalo ( 377) 358 45.7 0.00017
XP_016855778 (OMIM: 607410) PREDICTED: diencephalo ( 377) 358 45.7 0.00017
NP_852122 (OMIM: 122880,148820,193500,268220,60659 ( 479) 351 45.2 0.00031
NP_703149 (OMIM: 300154) homeobox protein ESX1 [Ho ( 406) 349 44.9 0.00031
NP_001120838 (OMIM: 122880,148820,193500,268220,60 ( 483) 350 45.1 0.00033
NP_852123 (OMIM: 122880,148820,193500,268220,60659 ( 484) 350 45.1 0.00033
NP_852124 (OMIM: 122880,148820,193500,268220,60659 ( 505) 350 45.1 0.00034
NP_671725 (OMIM: 607410) diencephalon/mesencephalo ( 382) 342 44.3 0.00046
NP_038463 (OMIM: 601881,611038) retinal homeobox p ( 346) 336 43.7 0.00063
NP_001263380 (OMIM: 606701) dorsal root ganglia ho ( 263) 325 42.6 0.001
NP_620689 (OMIM: 300004,300215,300382,300419,30835 ( 562) 333 43.6 0.0011
XP_016870292 (OMIM: 604675) PREDICTED: paired meso ( 193) 320 42.0 0.0011
NP_006483 (OMIM: 136760,606014) homeobox protein a ( 343) 324 42.6 0.0013
NP_001128726 (OMIM: 167410,268220) paired box prot ( 505) 328 43.1 0.0013
NP_057391 (OMIM: 604675) paired mesoderm homeobox ( 253) 320 42.1 0.0014
NP_001306003 (OMIM: 605726,610362,610381,613757) r ( 230) 317 41.8 0.0016
NP_039236 (OMIM: 167410,268220) paired box protein ( 518) 324 42.8 0.0018
NP_002575 (OMIM: 167410,268220) paired box protein ( 520) 324 42.8 0.0018
NP_001297090 (OMIM: 106210,120430,136520,148190,16 ( 286) 307 41.0 0.0034
NP_001297089 (OMIM: 106210,120430,136520,148190,16 ( 286) 307 41.0 0.0034
NP_002644 (OMIM: 119800,186550,602149) pituitary h ( 314) 307 41.0 0.0036
NP_116142 (OMIM: 605726,610362,610381,613757) reti ( 184) 298 40.0 0.0044
NP_000271 (OMIM: 106210,120430,136520,148190,16555 ( 422) 307 41.1 0.0044
NP_001245394 (OMIM: 106210,120430,136520,148190,16 ( 422) 307 41.1 0.0044
NP_001245393 (OMIM: 106210,120430,136520,148190,16 ( 422) 307 41.1 0.0044
NP_001121084 (OMIM: 106210,120430,136520,148190,16 ( 422) 307 41.1 0.0044
NP_001245391 (OMIM: 106210,120430,136520,148190,16 ( 436) 307 41.2 0.0045
NP_001297087 (OMIM: 106210,120430,136520,148190,16 ( 436) 307 41.2 0.0045
NP_001595 (OMIM: 106210,120430,136520,148190,16555 ( 436) 307 41.2 0.0045
NP_001245392 (OMIM: 106210,120430,136520,148190,16 ( 436) 307 41.2 0.0045
NP_852126 (OMIM: 122880,148820,193500,268220,60659 ( 403) 306 41.0 0.0046
NP_852125 (OMIM: 122880,148820,193500,268220,60659 ( 407) 306 41.0 0.0046
NP_068745 (OMIM: 605420,609597,613451,615529) home ( 411) 300 40.5 0.0067
NP_006252 (OMIM: 262600,601538) homeobox protein p ( 226) 288 39.1 0.0095
XP_011537084 (OMIM: 601527,613456) PREDICTED: ALX ( 231) 288 39.2 0.0096
>>NP_000545 (OMIM: 120970,268000,602225,613829) cone-rod (299 aa)
initn: 2047 init1: 2047 opt: 2047 Z-score: 1028.9 bits: 198.4 E(85289): 1.4e-50
Smith-Waterman score: 2047; 100.0% identity (100.0% similar) in 299 aa overlap (1-299:1-299)
10 20 30 40 50 60
pF1KB7 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 ASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGPALSPLSGP
190 200 210 220 230 240
250 260 270 280 290
pF1KB7 SVGPSLAQSPTSLSGQSYGAYSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SVGPSLAQSPTSLSGQSYGAYSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL
250 260 270 280 290
>>NP_001257452 (OMIM: 600037,610125,613986) homeobox pro (289 aa)
initn: 733 init1: 497 opt: 590 Z-score: 316.7 bits: 66.6 E(85289): 6.7e-11
Smith-Waterman score: 925; 52.1% identity (72.5% similar) in 309 aa overlap (1-299:1-289)
10 20 30 40 50 60
pF1KB7 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK
::.:.. : :.::.:.:. ..::.: .: ::..:::::::::::::.::. :::::::
NP_001 MMSYLKQPP-YAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAK
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK
:.:::.. ::::::::::::::::::::::::::::: :::: ::: :.::::.:
NP_001 TRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-----QQQQQNGGQNKVRPAKKK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 AGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLV
::: . .: . : : ...:: . ... : :::::::: ::: . .
NP_001 --TSP--AREVSSES-GTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDP-----L
120 130 140 150 160
190 200 210 220 230
pF1KB7 ASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLGGPA--LSP
... : . : :::. ::.. ..:.. .:::.:.: ::.:: :: ::. :::
NP_001 STSSSCMQRSYPMTYTQASGYS---QGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSP
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 LSGPSVGPSLAQSPTSLSGQSYGAYS-----PVDSLEFKDPTGTWKFTYNPMDPLDYKDQ
.. .: : :::.::: :.::: : .: :..:: :..::...: : ::::::
NP_001 MGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNA-DCLDYKDQ
230 240 250 260 270 280
pF1KB7 -SAWKFQIL
:.::::.:
NP_001 TSSWKFQVL
>>NP_001257453 (OMIM: 600037,610125,613986) homeobox pro (289 aa)
initn: 733 init1: 497 opt: 590 Z-score: 316.7 bits: 66.6 E(85289): 6.7e-11
Smith-Waterman score: 925; 52.1% identity (72.5% similar) in 309 aa overlap (1-299:1-289)
10 20 30 40 50 60
pF1KB7 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK
::.:.. : :.::.:.:. ..::.: .: ::..:::::::::::::.::. :::::::
NP_001 MMSYLKQPP-YAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAK
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK
:.:::.. ::::::::::::::::::::::::::::: :::: ::: :.::::.:
NP_001 TRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-----QQQQQNGGQNKVRPAKKK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 AGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLV
::: . .: . : : ...:: . ... : :::::::: ::: . .
NP_001 --TSP--AREVSSES-GTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDP-----L
120 130 140 150 160
190 200 210 220 230
pF1KB7 ASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLGGPA--LSP
... : . : :::. ::.. ..:.. .:::.:.: ::.:: :: ::. :::
NP_001 STSSSCMQRSYPMTYTQASGYS---QGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSP
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 LSGPSVGPSLAQSPTSLSGQSYGAYS-----PVDSLEFKDPTGTWKFTYNPMDPLDYKDQ
.. .: : :::.::: :.::: : .: :..:: :..::...: : ::::::
NP_001 MGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNA-DCLDYKDQ
230 240 250 260 270 280
pF1KB7 -SAWKFQIL
:.::::.:
NP_001 TSSWKFQVL
>>NP_758840 (OMIM: 600037,610125,613986) homeobox protei (289 aa)
initn: 733 init1: 497 opt: 590 Z-score: 316.7 bits: 66.6 E(85289): 6.7e-11
Smith-Waterman score: 925; 52.1% identity (72.5% similar) in 309 aa overlap (1-299:1-289)
10 20 30 40 50 60
pF1KB7 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK
::.:.. : :.::.:.:. ..::.: .: ::..:::::::::::::.::. :::::::
NP_758 MMSYLKQPP-YAVNGLSLTTSGMDLLHPSVGYPATPRKQRRERTTFTRAQLDVLEALFAK
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK
:.:::.. ::::::::::::::::::::::::::::: :::: ::: :.::::.:
NP_758 TRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-----QQQQQNGGQNKVRPAKKK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 AGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLPEAQRAGLV
::: . .: . : : ...:: . ... : :::::::: ::: . .
NP_758 --TSP--AREVSSES-GTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDP-----L
120 130 140 150 160
190 200 210 220 230
pF1KB7 ASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLGGPA--LSP
... : . : :::. ::.. ..:.. .:::.:.: ::.:: :: ::. :::
NP_758 STSSSCMQRSYPMTYTQASGYS---QGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSP
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 LSGPSVGPSLAQSPTSLSGQSYGAYS-----PVDSLEFKDPTGTWKFTYNPMDPLDYKDQ
.. .: : :::.::: :.::: : .: :..:: :..::...: : ::::::
NP_758 MGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNA-DCLDYKDQ
230 240 250 260 270 280
pF1KB7 -SAWKFQIL
:.::::.:
NP_758 TSSWKFQVL
>>NP_001186699 (OMIM: 600036) homeobox protein OTX1 [Hom (354 aa)
initn: 717 init1: 494 opt: 572 Z-score: 306.8 bits: 65.0 E(85289): 2.4e-10
Smith-Waterman score: 676; 40.7% identity (65.1% similar) in 332 aa overlap (1-293:1-324)
10 20 30 40 50 60
pF1KB7 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK
::.:.. : :..:.:.:.::..::.: .: ::..::::::::::::::::. :::::::
NP_001 MMSYLKQPP-YGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAK
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK
:.:::.. :::::::::::::::::::::::::::::.:. . .. :. . :. :....
NP_001 TRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPA-KKKSSPVRES
60 70 80 90 100 110
130 140 150 160
pF1KB7 AG-------TSPRPSTDVCPDPLGISDSYSPPLP---GPSGSPTTAVATVS------IWS
.: : : :... . . :.: .: : .:.:..:....: :::
NP_001 SGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWS
120 130 140 150 160 170
170 180 190 200
pF1KB7 PASESP--------LPEA----------QRAGLVASGPSLTSAPYAMTYAPASAFCSSPS
::: :: .:: ::. ::.: . ..: : :.:. .... .
NP_001 PASISPGSAPASVSVPEPLAAPSNTSCMQRS--VAAGAATAAASYPMSYGQGGSY---GQ
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB7 AYGSPSS-YFSGLD--PYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLS--GQSYGAY
.: .::: ::.:.: ::.:: . :::.. :.. . : . .:: : .
NP_001 GYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHH
240 250 260 270 280 290
270 280 290
pF1KB7 SPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL
. . :. ...: : ::::. .:
NP_001 HHHHHHHHQGYGGS-GLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQ
300 310 320 330 340 350
NP_001 VL
>>NP_055377 (OMIM: 600036) homeobox protein OTX1 [Homo s (354 aa)
initn: 717 init1: 494 opt: 572 Z-score: 306.8 bits: 65.0 E(85289): 2.4e-10
Smith-Waterman score: 676; 40.7% identity (65.1% similar) in 332 aa overlap (1-293:1-324)
10 20 30 40 50 60
pF1KB7 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAK
::.:.. : :..:.:.:.::..::.: .: ::..::::::::::::::::. :::::::
NP_055 MMSYLKQPP-YGMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAK
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 TQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRK
:.:::.. :::::::::::::::::::::::::::::.:. . .. :. . :. :....
NP_055 TRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPA-KKKSSPVRES
60 70 80 90 100 110
130 140 150 160
pF1KB7 AG-------TSPRPSTDVCPDPLGISDSYSPPLP---GPSGSPTTAVATVS------IWS
.: : : :... . . :.: .: : .:.:..:....: :::
NP_055 SGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWS
120 130 140 150 160 170
170 180 190 200
pF1KB7 PASESP--------LPEA----------QRAGLVASGPSLTSAPYAMTYAPASAFCSSPS
::: :: .:: ::. ::.: . ..: : :.:. .... .
NP_055 PASISPGSAPASVSVPEPLAAPSNTSCMQRS--VAAGAATAAASYPMSYGQGGSY---GQ
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB7 AYGSPSS-YFSGLD--PYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTSLS--GQSYGAY
.: .::: ::.:.: ::.:: . :::.. :.. . : . .:: : .
NP_055 GYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHH
240 250 260 270 280 290
270 280 290
pF1KB7 SPVDSLEFKDPTGTWKFTYNPMDPLDYKDQSAWKFQIL
. . :. ...: : ::::. .:
NP_055 HHHHHHHHQGYGGS-GLAFNSADCLDYKEPGAAAASSAWKLNFNSPDCLDYKDQASWRFQ
300 310 320 330 340 350
NP_055 VL
>>NP_068374 (OMIM: 600037,610125,613986) homeobox protei (297 aa)
initn: 646 init1: 410 opt: 564 Z-score: 303.8 bits: 64.2 E(85289): 3.5e-10
Smith-Waterman score: 899; 50.8% identity (70.7% similar) in 317 aa overlap (1-299:1-297)
10 20 30 40 50
pF1KB7 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYP--------SAPRKQRRERTTFTRSQLE
::.:.. : :.::.:.:. ..::.: .: :: ..:::::::::::::.::.
NP_068 MMSYLKQPP-YAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLD
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 ELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQA
::::::::.:::.. ::::::::::::::::::::::::::::: :::: :::
NP_068 VLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-----QQQQQNGGQN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 KARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLP
:.::::.: ::: . .: . : : ...:: . ... : :::::::: :::
NP_068 KVRPAKKK--TSP--AREVSSES-GTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLS
120 130 140 150 160
180 190 200 210 220 230
pF1KB7 EAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLG
. .... : . : :::. ::.. ..:.. .:::.:.: ::.:: ::
NP_068 DP-----LSTSSSCMQRSYPMTYTQASGYS---QGYAGSTSYFGGMDCGSYLTPMHHQLP
170 180 190 200 210 220
240 250 260 270 280
pF1KB7 GPA--LSPLSGPSVGPSLAQSPTSLSGQSYGAYS-----PVDSLEFKDPTGTWKFTYNPM
::. :::.. .: : :::.::: :.::: : .: :..:: :..::...:
NP_068 GPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNA-
230 240 250 260 270 280
290
pF1KB7 DPLDYKDQ-SAWKFQIL
: :::::: :.::::.:
NP_068 DCLDYKDQTSSWKFQVL
290
>>NP_001257454 (OMIM: 600037,610125,613986) homeobox pro (297 aa)
initn: 646 init1: 410 opt: 564 Z-score: 303.8 bits: 64.2 E(85289): 3.5e-10
Smith-Waterman score: 899; 50.8% identity (70.7% similar) in 317 aa overlap (1-299:1-297)
10 20 30 40 50
pF1KB7 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYP--------SAPRKQRRERTTFTRSQLE
::.:.. : :.::.:.:. ..::.: .: :: ..:::::::::::::.::.
NP_001 MMSYLKQPP-YAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLD
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 ELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQA
::::::::.:::.. ::::::::::::::::::::::::::::: :::: :::
NP_001 VLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-----QQQQQNGGQN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 KARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLP
:.::::.: ::: . .: . : : ...:: . ... : :::::::: :::
NP_001 KVRPAKKK--TSP--AREVSSES-GTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLS
120 130 140 150 160
180 190 200 210 220 230
pF1KB7 EAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLG
. .... : . : :::. ::.. ..:.. .:::.:.: ::.:: ::
NP_001 DP-----LSTSSSCMQRSYPMTYTQASGYS---QGYAGSTSYFGGMDCGSYLTPMHHQLP
170 180 190 200 210 220
240 250 260 270 280
pF1KB7 GPA--LSPLSGPSVGPSLAQSPTSLSGQSYGAYS-----PVDSLEFKDPTGTWKFTYNPM
::. :::.. .: : :::.::: :.::: : .: :..:: :..::...:
NP_001 GPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNA-
230 240 250 260 270 280
290
pF1KB7 DPLDYKDQ-SAWKFQIL
: :::::: :.::::.:
NP_001 DCLDYKDQTSSWKFQVL
290
>>NP_001012677 (OMIM: 611164) arginine-fifty homeobox [H (315 aa)
initn: 535 init1: 257 opt: 483 Z-score: 263.9 bits: 56.9 E(85289): 5.8e-08
Smith-Waterman score: 484; 39.5% identity (64.9% similar) in 248 aa overlap (30-270:69-304)
10 20 30 40 50
pF1KB7 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFA
: .: :....:::.::..: :::::::.
NP_001 LSKLECSGTVSAYCSLNLPGSTDPPTSASRVAATTAIRRRHKERTSFTHQQYEELEALFS
40 50 60 70 80 90
60 70 80 90 100 110
pF1KB7 KTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKR
.:..:: .:..::...:::: :.:::.::: : ..:.:::. .:. . :.:.
NP_001 QTMFPDRNLQEKLALRLDLPESTVKVWFRNRRFKLKKQQQQQSAKQR-----NQILPSKK
100 110 120 130 140 150
120 130 140 150 160 170
pF1KB7 KAGTSPRPSTDVCPDPLG----ISDSYSPPLPGPSGSPTT-AVATVSIWSPASESPLPEA
.. :::: : :.: . ::: :: ::. .:.. : .. : .:. . ..
NP_001 NVPTSPRTS----PSPYAFSPVISDFYSS-LPSQPLDPSNWAWNSTFTESSTSDFQMQDT
160 170 180 190 200
180 190 200 210 220 230
pF1KB7 QRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLSPMVPQLGGP--
: :::: :.: : : . . . :. :: : : :::: :.::
NP_001 QWERLVASVPALYSDAYDIFQII--ELYNLPDENEISSSSFHCLYQYLSPTKYQVGGQGS
210 220 230 240 250 260
240 250 260 270 280 290
pF1KB7 ALSPLSGPSVGPSLAQSPTSLSGQSYGAYSPVDSLEFKDPTGTWKFTYNPMDPLDYKDQS
.:: ..::.:: : ::. ....:.. ::: .:::::.
NP_001 SLSIFAGPAVGLSPAQTWPNMTSQAFEAYSLTDSLEFQKTSNMVDLGFL
270 280 290 300 310
pF1KB7 AWKFQIL
>>NP_005160 (OMIM: 602078,602753) paired mesoderm homeob (284 aa)
initn: 393 init1: 334 opt: 383 Z-score: 215.6 bits: 47.8 E(85289): 2.9e-05
Smith-Waterman score: 386; 37.5% identity (58.3% similar) in 240 aa overlap (7-222:48-279)
10 20 30
pF1KB7 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAP
: : . . :: : : :: .:: ..:
NP_005 ASAYGDFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCAL-GALRD--HQPAPYSAVP
20 30 40 50 60 70
40 50 60 70 80
pF1KB7 -------------RKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRV
::::: ::::: .::.::: .::.:.:::.:.:::.::::.: :.::
NP_005 YKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARV
80 90 100 110 120 130
90 100 110 120 130 140
pF1KB7 QVWFKNRRAKCRQQRQQQKQQQQPPGGQAKARPAKRKAGTSPRPSTD-VC-PDPLGISDS
::::.::::: : .:.. . . .: : :. .. . .. : . .: : : . ..
NP_005 QVWFQNRRAKFR--KQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASL
140 150 160 170 180 190
150 160 170 180 190
pF1KB7 YSPPLPG---PSGSPTT-AVATVSIWSPA-SESPLPEAQRAGLVASG---PSLTSAPYAM
:: :: : ::. :: : .:. . .:: : ::....: :. .:
NP_005 PPPPAPGLASPRLSPSPLPVALGSGPGPGPGPQPLKGALWAGVAGGGGGGPGAGAAELLK
200 210 220 230 240 250
200 210 220 230 240 250
pF1KB7 TYAPASAFCSSPSAY-GSPSSYFSGLDPYLSPMVPQLGGPALSPLSGPSVGPSLAQSPTS
.. :: :.:. . : ::. : :
NP_005 AWQPAE---SGPGPFSGVLSSFHRKPGPALKTNLF
260 270 280
299 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:53:04 2016 done: Sat Nov 5 07:53:05 2016
Total Scan time: 9.270 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]