Result of FASTA (omim) for
pF1KB7595
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7595, 233 aa
1>>>pF1KB7595 233 - 233 aa - 233 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1995+/-0.00032; mu= 15.0363+/- 0.020
mean_var=68.4581+/-13.734, 0's: 0 Z-trim(115.8): 22 B-trim: 9 in 1/49
Lambda= 0.155011
statistics sampled from 26557 (26579) to 26557 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.312), width: 16
Scan time: 6.770
The best scores are: opt bits E(85289)
NP_000585 (OMIM: 157300,191160,600807,611162) tumo ( 233) 1531 350.9 1.1e-96
NP_001153212 (OMIM: 153440,607507,608446,610988) l ( 205) 305 76.7 3.3e-14
XP_011512918 (OMIM: 153440,607507,608446,610988) P ( 205) 305 76.7 3.3e-14
XP_011512920 (OMIM: 153440,607507,608446,610988) P ( 205) 305 76.7 3.3e-14
NP_000586 (OMIM: 153440,607507,608446,610988) lymp ( 205) 305 76.7 3.3e-14
XP_011512919 (OMIM: 153440,607507,608446,610988) P ( 205) 305 76.7 3.3e-14
XP_011512917 (OMIM: 153440,607507,608446,610988) P ( 205) 305 76.7 3.3e-14
NP_000630 (OMIM: 134638,211980,601859) tumor necro ( 281) 239 62.0 1.2e-09
NP_742011 (OMIM: 604520) tumor necrosis factor lig ( 204) 234 60.8 2e-09
XP_016882906 (OMIM: 604520) PREDICTED: tumor necro ( 240) 234 60.9 2.2e-09
NP_003798 (OMIM: 604520) tumor necrosis factor lig ( 240) 234 60.9 2.2e-09
NP_005109 (OMIM: 604052) tumor necrosis factor lig ( 251) 231 60.2 3.7e-09
NP_001191273 (OMIM: 604052) tumor necrosis factor ( 192) 227 59.3 5.6e-09
XP_016876292 (OMIM: 259710,602642) PREDICTED: tumo ( 244) 172 47.0 3.4e-05
XP_011533582 (OMIM: 259710,602642) PREDICTED: tumo ( 244) 172 47.0 3.4e-05
NP_143026 (OMIM: 259710,602642) tumor necrosis fac ( 244) 172 47.0 3.4e-05
XP_016876291 (OMIM: 259710,602642) PREDICTED: tumo ( 263) 172 47.0 3.6e-05
NP_003692 (OMIM: 259710,602642) tumor necrosis fac ( 317) 172 47.1 4.2e-05
NP_000065 (OMIM: 300386,308230) CD40 ligand [Homo ( 261) 153 42.8 0.00068
NP_003801 (OMIM: 603598) tumor necrosis factor lig ( 281) 153 42.8 0.00072
NP_002332 (OMIM: 600978) lymphotoxin-beta isoform ( 244) 137 39.2 0.0077
>>NP_000585 (OMIM: 157300,191160,600807,611162) tumor ne (233 aa)
initn: 1531 init1: 1531 opt: 1531 Z-score: 1857.1 bits: 350.9 E(85289): 1.1e-96
Smith-Waterman score: 1531; 100.0% identity (100.0% similar) in 233 aa overlap (1-233:1-233)
10 20 30 40 50 60
pF1KB7 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 EEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRE
130 140 150 160 170 180
190 200 210 220 230
pF1KB7 TPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
190 200 210 220 230
>>NP_001153212 (OMIM: 153440,607507,608446,610988) lymph (205 aa)
initn: 289 init1: 178 opt: 305 Z-score: 376.1 bits: 76.7 E(85289): 3.3e-14
Smith-Waterman score: 305; 32.4% identity (62.8% similar) in 207 aa overlap (38-233:8-205)
10 20 30 40 50 60
pF1KB7 RDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFG---VIGPQREEFP
:: . .::: :: .: :. : . .:
NP_001 MTPPERLFLPRVCGTTLHLLL-LGLLLVLLPGAQGLP
10 20 30
70 80 90 100 110 120
pF1KB7 RDLSLISPLAQAVRSSSRT----PSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR
..: ::..:. . . ::.::....:. ...: : :.: .: :
NP_001 -GVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLS
40 50 60 70 80 90
130 140 150 160 170
pF1KB7 DNQLVVPSEGLYLIYSQVLFKGQG-CP---STHVLLTHTISRIAVSYQTKVNLLSAIKSP
.:.:.::. :.:..::::.:.:.. : :. . :.: .. .. .: .: :::.
NP_001 NNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSS----
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 CQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
:. . : . .:: . .: :..::: .::.::.. . .: .. : :.:: .::
NP_001 -QKMVYPGLQ-EPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPS-TVFFGAFAL
160 170 180 190 200
>>XP_011512918 (OMIM: 153440,607507,608446,610988) PREDI (205 aa)
initn: 289 init1: 178 opt: 305 Z-score: 376.1 bits: 76.7 E(85289): 3.3e-14
Smith-Waterman score: 305; 32.4% identity (62.8% similar) in 207 aa overlap (38-233:8-205)
10 20 30 40 50 60
pF1KB7 RDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFG---VIGPQREEFP
:: . .::: :: .: :. : . .:
XP_011 MTPPERLFLPRVCGTTLHLLL-LGLLLVLLPGAQGLP
10 20 30
70 80 90 100 110 120
pF1KB7 RDLSLISPLAQAVRSSSRT----PSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR
..: ::..:. . . ::.::....:. ...: : :.: .: :
XP_011 -GVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLS
40 50 60 70 80 90
130 140 150 160 170
pF1KB7 DNQLVVPSEGLYLIYSQVLFKGQG-CP---STHVLLTHTISRIAVSYQTKVNLLSAIKSP
.:.:.::. :.:..::::.:.:.. : :. . :.: .. .. .: .: :::.
XP_011 NNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSS----
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 CQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
:. . : . .:: . .: :..::: .::.::.. . .: .. : :.:: .::
XP_011 -QKMVYPGLQ-EPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPS-TVFFGAFAL
160 170 180 190 200
>>XP_011512920 (OMIM: 153440,607507,608446,610988) PREDI (205 aa)
initn: 289 init1: 178 opt: 305 Z-score: 376.1 bits: 76.7 E(85289): 3.3e-14
Smith-Waterman score: 305; 32.4% identity (62.8% similar) in 207 aa overlap (38-233:8-205)
10 20 30 40 50 60
pF1KB7 RDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFG---VIGPQREEFP
:: . .::: :: .: :. : . .:
XP_011 MTPPERLFLPRVCGTTLHLLL-LGLLLVLLPGAQGLP
10 20 30
70 80 90 100 110 120
pF1KB7 RDLSLISPLAQAVRSSSRT----PSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR
..: ::..:. . . ::.::....:. ...: : :.: .: :
XP_011 -GVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLS
40 50 60 70 80 90
130 140 150 160 170
pF1KB7 DNQLVVPSEGLYLIYSQVLFKGQG-CP---STHVLLTHTISRIAVSYQTKVNLLSAIKSP
.:.:.::. :.:..::::.:.:.. : :. . :.: .. .. .: .: :::.
XP_011 NNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSS----
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 CQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
:. . : . .:: . .: :..::: .::.::.. . .: .. : :.:: .::
XP_011 -QKMVYPGLQ-EPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPS-TVFFGAFAL
160 170 180 190 200
>>NP_000586 (OMIM: 153440,607507,608446,610988) lymphoto (205 aa)
initn: 289 init1: 178 opt: 305 Z-score: 376.1 bits: 76.7 E(85289): 3.3e-14
Smith-Waterman score: 305; 32.4% identity (62.8% similar) in 207 aa overlap (38-233:8-205)
10 20 30 40 50 60
pF1KB7 RDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFG---VIGPQREEFP
:: . .::: :: .: :. : . .:
NP_000 MTPPERLFLPRVCGTTLHLLL-LGLLLVLLPGAQGLP
10 20 30
70 80 90 100 110 120
pF1KB7 RDLSLISPLAQAVRSSSRT----PSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR
..: ::..:. . . ::.::....:. ...: : :.: .: :
NP_000 -GVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLS
40 50 60 70 80 90
130 140 150 160 170
pF1KB7 DNQLVVPSEGLYLIYSQVLFKGQG-CP---STHVLLTHTISRIAVSYQTKVNLLSAIKSP
.:.:.::. :.:..::::.:.:.. : :. . :.: .. .. .: .: :::.
NP_000 NNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSS----
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 CQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
:. . : . .:: . .: :..::: .::.::.. . .: .. : :.:: .::
NP_000 -QKMVYPGLQ-EPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPS-TVFFGAFAL
160 170 180 190 200
>>XP_011512919 (OMIM: 153440,607507,608446,610988) PREDI (205 aa)
initn: 289 init1: 178 opt: 305 Z-score: 376.1 bits: 76.7 E(85289): 3.3e-14
Smith-Waterman score: 305; 32.4% identity (62.8% similar) in 207 aa overlap (38-233:8-205)
10 20 30 40 50 60
pF1KB7 RDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFG---VIGPQREEFP
:: . .::: :: .: :. : . .:
XP_011 MTPPERLFLPRVCGTTLHLLL-LGLLLVLLPGAQGLP
10 20 30
70 80 90 100 110 120
pF1KB7 RDLSLISPLAQAVRSSSRT----PSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR
..: ::..:. . . ::.::....:. ...: : :.: .: :
XP_011 -GVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLS
40 50 60 70 80 90
130 140 150 160 170
pF1KB7 DNQLVVPSEGLYLIYSQVLFKGQG-CP---STHVLLTHTISRIAVSYQTKVNLLSAIKSP
.:.:.::. :.:..::::.:.:.. : :. . :.: .. .. .: .: :::.
XP_011 NNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSS----
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 CQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
:. . : . .:: . .: :..::: .::.::.. . .: .. : :.:: .::
XP_011 -QKMVYPGLQ-EPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPS-TVFFGAFAL
160 170 180 190 200
>>XP_011512917 (OMIM: 153440,607507,608446,610988) PREDI (205 aa)
initn: 289 init1: 178 opt: 305 Z-score: 376.1 bits: 76.7 E(85289): 3.3e-14
Smith-Waterman score: 305; 32.4% identity (62.8% similar) in 207 aa overlap (38-233:8-205)
10 20 30 40 50 60
pF1KB7 RDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFG---VIGPQREEFP
:: . .::: :: .: :. : . .:
XP_011 MTPPERLFLPRVCGTTLHLLL-LGLLLVLLPGAQGLP
10 20 30
70 80 90 100 110 120
pF1KB7 RDLSLISPLAQAVRSSSRT----PSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR
..: ::..:. . . ::.::....:. ...: : :.: .: :
XP_011 -GVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLS
40 50 60 70 80 90
130 140 150 160 170
pF1KB7 DNQLVVPSEGLYLIYSQVLFKGQG-CP---STHVLLTHTISRIAVSYQTKVNLLSAIKSP
.:.:.::. :.:..::::.:.:.. : :. . :.: .. .. .: .: :::.
XP_011 NNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSS----
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 CQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
:. . : . .:: . .: :..::: .::.::.. . .: .. : :.:: .::
XP_011 -QKMVYPGLQ-EPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPS-TVFFGAFAL
160 170 180 190 200
>>NP_000630 (OMIM: 134638,211980,601859) tumor necrosis (281 aa)
initn: 172 init1: 116 opt: 239 Z-score: 294.3 bits: 62.0 E(85289): 1.2e-09
Smith-Waterman score: 259; 27.4% identity (58.7% similar) in 223 aa overlap (18-233:70-281)
10 20 30 40
pF1KB7 MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLI--VAGAT
: : : ... ::.. .: :. :. .
NP_000 PGQRRPPPPPPPPPLPPPPPPPPLPPLPLPPLKKRGNHSTGLCLLVMFFMVLVALVGLGL
40 50 60 70 80 90
50 60 70 80 90 100
pF1KB7 TLFCLLHFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKP---VAHVVANPQAEGQ-
.: :.:. . .: .. : : . . : : : :::.... .....
NP_000 GMFQLFHLQKELAELRESTSQMHTASSLEKQIGHPSPPPEKKELRKVAHLTGKSNSRSMP
100 110 120 130 140 150
110 120 130 140 150 160
pF1KB7 LQWLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAV
:.: . . .::. ::. . . ::. :::..::.: :.::.: ... :.: .
NP_000 LEWEDTYGIVLLS-GVKYKKGGLVINETGLYFVYSKVYFRGQSC--NNLPLSHKVYMRNS
160 170 180 190 200 210
170 180 190 200 210 220
pF1KB7 SY-QTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDF
.: : : . . . : : . .. : . :::.::.: ..:.: ..... . ..:
NP_000 KYPQDLVMMEGKMMSYC-------TTGQMWARSSYLGAVFNLTSADHLYVNVSELSLVNF
220 230 240 250 260
230
pF1KB7 AESGQVYFGIIAL
:: :..::. :
NP_000 EES-QTFFGLYKL
270 280
>>NP_742011 (OMIM: 604520) tumor necrosis factor ligand (204 aa)
initn: 233 init1: 99 opt: 234 Z-score: 290.3 bits: 60.8 E(85289): 2e-09
Smith-Waterman score: 234; 30.7% identity (60.1% similar) in 153 aa overlap (82-229:52-200)
60 70 80 90 100
pF1KB7 HFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVV-ANPQAEGQ---LQWLNR
:. .:.::.. :: . :. : : ..
NP_742 TRLGRSHRRQSCSVARDGPAGSWEQLIQERRSHEVNPAAHLTGANSSLTGSGGPLLWETQ
30 40 50 60 70 80
110 120 130 140 150 160
pF1KB7 RANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCP-STHVLLTHTISRIAVSYQTK
. :.: :. .:. ::: . : : :::.: . : ::: . .:: . . . : .
NP_742 LGLAFL-RGLSYHDGALVVTKAGYYYIYSKVQLGGVGCPLGLASTITHGLYKRTPRYPEE
90 100 110 120 130 140
170 180 190 200 210 220
pF1KB7 VNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQV
..:: . .::: : : . .. :.. .:::: .:: :... ... . . .. .
NP_742 LELLVSQQSPCGRAT---SSSRVWWDSSFLGGVVHLEAGEKVVVRVLDERLVRLRDGTRS
150 160 170 180 190
230
pF1KB7 YFGIIAL
:::
NP_742 YFGAFMV
200
>>XP_016882906 (OMIM: 604520) PREDICTED: tumor necrosis (240 aa)
initn: 233 init1: 99 opt: 234 Z-score: 289.3 bits: 60.9 E(85289): 2.2e-09
Smith-Waterman score: 234; 30.7% identity (60.1% similar) in 153 aa overlap (82-229:88-236)
60 70 80 90 100
pF1KB7 HFGVIGPQREEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVV-ANPQAEGQ---LQWLNR
:. .:.::.. :: . :. : : ..
XP_016 LLQLHWRLGEMVTRLPDGPAGSWEQLIQERRSHEVNPAAHLTGANSSLTGSGGPLLWETQ
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB7 RANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCP-STHVLLTHTISRIAVSYQTK
. :.: :. .:. ::: . : : :::.: . : ::: . .:: . . . : .
XP_016 LGLAFL-RGLSYHDGALVVTKAGYYYIYSKVQLGGVGCPLGLASTITHGLYKRTPRYPEE
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 VNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQV
..:: . .::: : : . .. :.. .:::: .:: :... ... . . .. .
XP_016 LELLVSQQSPCGRAT---SSSRVWWDSSFLGGVVHLEAGEKVVVRVLDERLVRLRDGTRS
180 190 200 210 220 230
230
pF1KB7 YFGIIAL
:::
XP_016 YFGAFMV
240
233 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 08:55:13 2016 done: Fri Nov 4 08:55:14 2016
Total Scan time: 6.770 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]