Result of FASTA (omim) for
pF1KB7394
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7394, 204 aa
1>>>pF1KB7394 204 - 204 aa - 204 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0453+/-0.000292; mu= 3.8339+/- 0.018
mean_var=204.7351+/-41.647, 0's: 0 Z-trim(124.8): 151 B-trim: 323 in 1/56
Lambda= 0.089635
statistics sampled from 47104 (47275) to 47104 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.837), E-opt: 0.2 (0.554), width: 16
Scan time: 6.280
The best scores are: opt bits E(85289)
NP_001303 (OMIM: 601183) cysteine-rich protein 2 i ( 208) 985 138.4 8e-33
NP_001257766 (OMIM: 601183) cysteine-rich protein ( 282) 929 131.3 1.5e-30
NP_001257770 (OMIM: 601183) cysteine-rich protein ( 87) 454 69.4 2e-12
NP_001302 (OMIM: 123875) cysteine-rich protein 1 [ ( 77) 378 59.5 1.7e-09
NP_003467 (OMIM: 600824,607482,612124) cysteine an ( 194) 310 51.1 1.4e-06
NP_001287894 (OMIM: 601871) cysteine and glycine-r ( 193) 258 44.3 0.00015
NP_001312 (OMIM: 601871) cysteine and glycine-rich ( 193) 258 44.3 0.00015
XP_005253974 (OMIM: 602505) PREDICTED: paxillin is ( 403) 258 44.6 0.00026
XP_016875232 (OMIM: 602505) PREDICTED: paxillin is ( 424) 258 44.7 0.00027
NP_079433 (OMIM: 602505) paxillin isoform 4 [Homo ( 424) 258 44.7 0.00027
NP_001180500 (OMIM: 123876) cysteine and glycine-r ( 193) 251 43.4 0.00028
NP_004069 (OMIM: 123876) cysteine and glycine-rich ( 193) 251 43.4 0.00028
NP_001180501 (OMIM: 123876) cysteine and glycine-r ( 193) 251 43.4 0.00028
NP_002850 (OMIM: 602505) paxillin isoform 1 [Homo ( 557) 258 44.8 0.00032
XP_016875231 (OMIM: 602505) PREDICTED: paxillin is ( 563) 258 44.8 0.00033
XP_016875230 (OMIM: 602505) PREDICTED: paxillin is ( 589) 258 44.8 0.00034
NP_001074324 (OMIM: 602505) paxillin isoform 2 [Ho ( 591) 258 44.8 0.00034
XP_016875229 (OMIM: 602505) PREDICTED: paxillin is ( 597) 258 44.8 0.00034
NP_001230685 (OMIM: 602505) paxillin isoform 3 [Ho ( 605) 258 44.8 0.00034
XP_016875228 (OMIM: 602505) PREDICTED: paxillin is ( 611) 258 44.8 0.00035
XP_016875227 (OMIM: 602505) PREDICTED: paxillin is ( 645) 258 44.8 0.00036
XP_016875226 (OMIM: 602505) PREDICTED: paxillin is ( 700) 258 44.9 0.00038
XP_016875225 (OMIM: 602505) PREDICTED: paxillin is ( 748) 258 44.9 0.0004
XP_016875224 (OMIM: 602505) PREDICTED: paxillin is ( 858) 258 44.9 0.00044
XP_016875223 (OMIM: 602505) PREDICTED: paxillin is ( 888) 258 45.0 0.00045
XP_016875222 (OMIM: 602505) PREDICTED: paxillin is ( 940) 258 45.0 0.00047
XP_011536925 (OMIM: 602505) PREDICTED: paxillin is ( 996) 258 45.0 0.00049
XP_016875220 (OMIM: 602505) PREDICTED: paxillin is ( 996) 258 45.0 0.00049
XP_006719598 (OMIM: 602505) PREDICTED: paxillin is ( 996) 258 45.0 0.00049
XP_006719597 (OMIM: 602505) PREDICTED: paxillin is ( 996) 258 45.0 0.00049
XP_011536924 (OMIM: 602505) PREDICTED: paxillin is ( 996) 258 45.0 0.00049
XP_006719599 (OMIM: 602505) PREDICTED: paxillin is ( 996) 258 45.0 0.00049
XP_016875218 (OMIM: 602505) PREDICTED: paxillin is (1087) 258 45.0 0.00052
XP_016875217 (OMIM: 602505) PREDICTED: paxillin is (1127) 258 45.1 0.00054
XP_006719595 (OMIM: 602505) PREDICTED: paxillin is (1129) 258 45.1 0.00054
XP_016875216 (OMIM: 602505) PREDICTED: paxillin is (1130) 258 45.1 0.00054
XP_016875215 (OMIM: 602505) PREDICTED: paxillin is (1135) 258 45.1 0.00054
NP_057011 (OMIM: 602353) transforming growth facto ( 444) 248 43.4 0.00067
NP_001158191 (OMIM: 602353) transforming growth fa ( 444) 248 43.4 0.00067
NP_001035919 (OMIM: 602353) transforming growth fa ( 461) 248 43.4 0.00069
XP_006718813 (OMIM: 605390) PREDICTED: leupaxin is ( 290) 228 40.6 0.003
XP_011543692 (OMIM: 605390) PREDICTED: leupaxin is ( 366) 228 40.7 0.0035
XP_011543693 (OMIM: 605390) PREDICTED: leupaxin is ( 366) 228 40.7 0.0035
NP_001294880 (OMIM: 605390) leupaxin isoform 3 [Ho ( 366) 228 40.7 0.0035
XP_011543690 (OMIM: 605390) PREDICTED: leupaxin is ( 366) 228 40.7 0.0035
NP_004802 (OMIM: 605390) leupaxin isoform 2 [Homo ( 386) 228 40.7 0.0037
NP_001137467 (OMIM: 605390) leupaxin isoform 1 [Ho ( 391) 228 40.7 0.0037
XP_016859580 (OMIM: 602567) PREDICTED: LIM and sen ( 317) 218 39.4 0.0078
XP_016859583 (OMIM: 602567) PREDICTED: LIM and sen ( 317) 218 39.4 0.0078
XP_016859582 (OMIM: 602567) PREDICTED: LIM and sen ( 317) 218 39.4 0.0078
>>NP_001303 (OMIM: 601183) cysteine-rich protein 2 isofo (208 aa)
initn: 959 init1: 480 opt: 985 Z-score: 710.3 bits: 138.4 E(85289): 8e-33
Smith-Waterman score: 985; 63.3% identity (80.9% similar) in 199 aa overlap (1-197:1-199)
10 20 30 40 50 60
pF1KB7 MSWTCPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGA
:. ::.:.. :.::::::::::.::.:::::::: . :.:::::::.:.:.::::::..
NP_001 MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHKPCYAT
10 20 30 40 50 60
70 80 90 100 110
pF1KB7 LFGPRGVNIGGVGSYLYNPP-TPSPGCTTPLS-PSSFSPPRPRTGLPQGKKSPPHMKTFT
::::.::::::.:::.:. : . .: : :. :.. . : .: :.: . . :::
NP_001 LFGPKGVNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 GETSLCPGCGEPVYFAEKVMSLGRNWHRPCLRCQRCHKTLTAGSHAEHDGVPYCHVPCYG
:: . :: :.. ::::::: :::..::::::::.:: :::: :.:::::: :::: ::::
NP_001 GEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCHKPCYG
130 140 150 160 170 180
180 190 200
pF1KB7 YLFGPKGVNIGDVGCYIYDPVKIKFK
:::::::: : :: ::::
NP_001 ILFGPKGVNTGAVGSYIYDRDPEGKVQP
190 200
>>NP_001257766 (OMIM: 601183) cysteine-rich protein 2 is (282 aa)
initn: 882 init1: 480 opt: 929 Z-score: 669.5 bits: 131.3 E(85289): 1.5e-30
Smith-Waterman score: 929; 62.6% identity (78.3% similar) in 198 aa overlap (2-197:77-273)
10 20 30
pF1KB7 MSWTCPRCQQPVFFAEKVSSLGKNWHRFCLK
: :: .: :::::::::.::.::::
NP_001 GCVCKGGGCCHREPSQDHHESQEHRGPLVGSQTC-LVHQAEGTAEKVSSLGKDWHKFCLK
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB7 CERCHSILSPGGHAEHNGRPYCHKPCYGALFGPRGVNIGGVGSYLYNPP-TPSPGCTTPL
:::: . :.:::::::.:.:.::::::..::::.::::::.:::.:. : . .: : :.
NP_001 CERCSKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPLAEGPQVTGPI
110 120 130 140 150 160
100 110 120 130 140
pF1KB7 S-PSSFSPPRPRTGLPQGKKSPPHMKTFTGETSLCPGCGEPVYFAEKVMSLGRNWHRPCL
:.. . : .: :.: . . ::::: . :: :.. ::::::: :::..::::::
NP_001 EVPAARAEERKASGPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCL
170 180 190 200 210 220
150 160 170 180 190 200
pF1KB7 RCQRCHKTLTAGSHAEHDGVPYCHVPCYGYLFGPKGVNIGDVGCYIYDPVKIKFK
::.:: :::: :.:::::: :::: :::: :::::::: : :: ::::
NP_001 RCERCGKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP
230 240 250 260 270 280
>>NP_001257770 (OMIM: 601183) cysteine-rich protein 2 is (87 aa)
initn: 451 init1: 451 opt: 454 Z-score: 344.1 bits: 69.4 E(85289): 2e-12
Smith-Waterman score: 454; 69.2% identity (89.7% similar) in 78 aa overlap (1-78:1-78)
10 20 30 40 50 60
pF1KB7 MSWTCPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGA
:. ::.:.. :.:::::.::::.::: ::.:::: . :.:::::::.:.:::::::::
NP_001 MASKCPKCDKTVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCHKPCYGI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LFGPRGVNIGGVGSYLYNPPTPSPGCTTPLSPSSFSPPRPRTGLPQGKKSPPHMKTFTGE
::::.::: :.::::.:.
NP_001 LFGPKGVNTGAVGSYIYDRDPEGKVQP
70 80
>>NP_001302 (OMIM: 123875) cysteine-rich protein 1 [Homo (77 aa)
initn: 378 init1: 378 opt: 378 Z-score: 291.7 bits: 59.5 E(85289): 1.7e-09
Smith-Waterman score: 378; 58.9% identity (87.7% similar) in 73 aa overlap (5-77:4-76)
10 20 30 40 50 60
pF1KB7 MSWTCPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGA
::.:.. :.:::.:.::::.::: :::::.: . :. ::::::.:.:::..:::.:
NP_001 MPKCPKCNKEVYFAERVTSLGKDWHRPCLKCEKCGKTLTSGGHAEHEGKPYCNHPCYAA
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 LFGPRGVNIGGVGSYLYNPPTPSPGCTTPLSPSSFSPPRPRTGLPQGKKSPPHMKTFTGE
.:::.: . ::. :. .
NP_001 MFGPKGFGRGGAESHTFK
60 70
>>NP_003467 (OMIM: 600824,607482,612124) cysteine and gl (194 aa)
initn: 403 init1: 209 opt: 310 Z-score: 239.0 bits: 51.1 E(85289): 1.4e-06
Smith-Waterman score: 429; 35.1% identity (61.1% similar) in 185 aa overlap (5-189:10-184)
10 20 30 40 50
pF1KB7 MSWTCPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHK
: :.. :. ::... :...:. :..: :.. :. : :... :: :
NP_003 MPNWGGGAKCGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYC-K
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 PCYGALFGPRGVNIGGVGSYLYNPPTPSPGCTTPLSPSSFSPPRPRTGLPQGKKSPPHMK
::: .::.:.. : .. : . : ::. : : : ..: ..
NP_003 VCYGRRYGPKGIGYGQGAGCLSTDTGEHLGLQFQQSPK---PARSVT-----TSNPSKFT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 TFTGETSLCPGCGEPVYFAEKVMSLGRNWHRPCLRCQRCHKTLTAGSHAEHDGVPYCHVP
. ::. :: ::. :: :::::. :. ::. :.:: : :.: . . ...:: ::.:
NP_003 AKFGESEKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYCKV-
120 130 140 150 160 170
180 190 200
pF1KB7 CYGYLFGPKGVNIGDVGCYIYDPVKIKFK
::. ::: :...:
NP_003 CYAKNFGPTGIGFGGLTQQVEKKE
180 190
>>NP_001287894 (OMIM: 601871) cysteine and glycine-rich (193 aa)
initn: 389 init1: 185 opt: 258 Z-score: 202.6 bits: 44.3 E(85289): 0.00015
Smith-Waterman score: 416; 35.5% identity (60.2% similar) in 186 aa overlap (5-189:10-183)
10 20 30 40 50
pF1KB7 MSWTCPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHK
: : . :. ::.:. :...:: :. : :.. :. : :. . :: :
NP_001 MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYC-K
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 PCYGALFGPRGVNIG-GVGSYLYNPPTPSPGCTTPLSPSSFSPPRPRTGLPQGKKSPPHM
::: .::.: . : :.:. .. : ..: : .: :: :. :. .:
NP_001 SCYGKKYGPKGYGYGQGAGTLNMDR-----GERLGIKPESVQPHRPTTN-PNTSK---FA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 KTFTGETSLCPGCGEPVYFAEKVMSLGRNWHRPCLRCQRCHKTLTAGSHAEHDGVPYCHV
. . : . : ::. :: :::... :. ::. :.:: .: :.: . . .:..: ::.
NP_001 QKYGGAEK-CSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK-
120 130 140 150 160
180 190 200
pF1KB7 PCYGYLFGPKGVNIGDVGCYIYDPVKIKFK
::. ::::: . :
NP_001 GCYAKNFGPKGFGYGQGAGALVHAQ
170 180 190
>>NP_001312 (OMIM: 601871) cysteine and glycine-rich pro (193 aa)
initn: 389 init1: 185 opt: 258 Z-score: 202.6 bits: 44.3 E(85289): 0.00015
Smith-Waterman score: 416; 35.5% identity (60.2% similar) in 186 aa overlap (5-189:10-183)
10 20 30 40 50
pF1KB7 MSWTCPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHK
: : . :. ::.:. :...:: :. : :.. :. : :. . :: :
NP_001 MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYC-K
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 PCYGALFGPRGVNIG-GVGSYLYNPPTPSPGCTTPLSPSSFSPPRPRTGLPQGKKSPPHM
::: .::.: . : :.:. .. : ..: : .: :: :. :. .:
NP_001 SCYGKKYGPKGYGYGQGAGTLNMDR-----GERLGIKPESVQPHRPTTN-PNTSK---FA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 KTFTGETSLCPGCGEPVYFAEKVMSLGRNWHRPCLRCQRCHKTLTAGSHAEHDGVPYCHV
. . : . : ::. :: :::... :. ::. :.:: .: :.: . . .:..: ::.
NP_001 QKYGGAEK-CSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCK-
120 130 140 150 160
180 190 200
pF1KB7 PCYGYLFGPKGVNIGDVGCYIYDPVKIKFK
::. ::::: . :
NP_001 GCYAKNFGPKGFGYGQGAGALVHAQ
170 180 190
>>XP_005253974 (OMIM: 602505) PREDICTED: paxillin isofor (403 aa)
initn: 258 init1: 130 opt: 258 Z-score: 198.5 bits: 44.6 E(85289): 0.00026
Smith-Waterman score: 268; 27.9% identity (54.7% similar) in 179 aa overlap (5-174:170-337)
10 20 30
pF1KB7 MSWTCPRCQQPVFFAEKVSSLGKNWHRFCLKCER
: :..:. .. :...::.:: . : .
XP_005 PKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIA-GQVVTAMGKTWHPEHFVCTH
140 150 160 170 180 190
40 50 60 70 80
pF1KB7 CHSILSPGGHAEHNGRPYCHKPCYGALFGPR-----GVNIGGVGSYLYNPPTPS----PG
:. .. . :..:.:::.: : ::.:: : . : . : :
XP_005 CQEEIGSRNFFERDGQPYCEKD-YHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQ
200 210 220 230 240 250
90 100 110 120 130 140
pF1KB7 CTTPLSPSSFSPPRPRTGLPQGKKSPPHMKTFTGETSLCPGCGEPVYFAEKVMSLGRNWH
: . ..: .: . . : .:. .. :. . : ::.. . . . . .:. ::
XP_005 CGAFFGPEGF---HEKDGKAYCRKD--YFDMFAPK---CGGCARAI-LENYISALNTLWH
260 270 280 290 300
150 160 170 180 190 200
pF1KB7 RPCLRCQRCHKTLTAGSHAEHDGVPYCHVPCYGYLFGPKGVNIGDVGCYIYDPVKIKFK
:. :..: .. :: :::: :::.:
XP_005 PECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHP
310 320 330 340 350 360
>>XP_016875232 (OMIM: 602505) PREDICTED: paxillin isofor (424 aa)
initn: 258 init1: 130 opt: 258 Z-score: 198.2 bits: 44.7 E(85289): 0.00027
Smith-Waterman score: 268; 27.9% identity (54.7% similar) in 179 aa overlap (5-174:191-358)
10 20 30
pF1KB7 MSWTCPRCQQPVFFAEKVSSLGKNWHRFCLKCER
: :..:. .. :...::.:: . : .
XP_016 PKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIA-GQVVTAMGKTWHPEHFVCTH
170 180 190 200 210
40 50 60 70 80
pF1KB7 CHSILSPGGHAEHNGRPYCHKPCYGALFGPR-----GVNIGGVGSYLYNPPTPS----PG
:. .. . :..:.:::.: : ::.:: : . : . : :
XP_016 CQEEIGSRNFFERDGQPYCEKD-YHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQ
220 230 240 250 260 270
90 100 110 120 130 140
pF1KB7 CTTPLSPSSFSPPRPRTGLPQGKKSPPHMKTFTGETSLCPGCGEPVYFAEKVMSLGRNWH
: . ..: .: . . : .:. .. :. . : ::.. . . . . .:. ::
XP_016 CGAFFGPEGF---HEKDGKAYCRKD--YFDMFAPK---CGGCARAI-LENYISALNTLWH
280 290 300 310 320
150 160 170 180 190 200
pF1KB7 RPCLRCQRCHKTLTAGSHAEHDGVPYCHVPCYGYLFGPKGVNIGDVGCYIYDPVKIKFK
:. :..: .. :: :::: :::.:
XP_016 PECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHP
330 340 350 360 370 380
>>NP_079433 (OMIM: 602505) paxillin isoform 4 [Homo sapi (424 aa)
initn: 258 init1: 130 opt: 258 Z-score: 198.2 bits: 44.7 E(85289): 0.00027
Smith-Waterman score: 268; 27.9% identity (54.7% similar) in 179 aa overlap (5-174:191-358)
10 20 30
pF1KB7 MSWTCPRCQQPVFFAEKVSSLGKNWHRFCLKCER
: :..:. .. :...::.:: . : .
NP_079 PKPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIA-GQVVTAMGKTWHPEHFVCTH
170 180 190 200 210
40 50 60 70 80
pF1KB7 CHSILSPGGHAEHNGRPYCHKPCYGALFGPR-----GVNIGGVGSYLYNPPTPS----PG
:. .. . :..:.:::.: : ::.:: : . : . : :
NP_079 CQEEIGSRNFFERDGQPYCEKD-YHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQ
220 230 240 250 260 270
90 100 110 120 130 140
pF1KB7 CTTPLSPSSFSPPRPRTGLPQGKKSPPHMKTFTGETSLCPGCGEPVYFAEKVMSLGRNWH
: . ..: .: . . : .:. .. :. . : ::.. . . . . .:. ::
NP_079 CGAFFGPEGF---HEKDGKAYCRKD--YFDMFAPK---CGGCARAI-LENYISALNTLWH
280 290 300 310 320
150 160 170 180 190 200
pF1KB7 RPCLRCQRCHKTLTAGSHAEHDGVPYCHVPCYGYLFGPKGVNIGDVGCYIYDPVKIKFK
:. :..: .. :: :::: :::.:
NP_079 PECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHP
330 340 350 360 370 380
204 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 07:21:48 2016 done: Fri Nov 4 07:21:49 2016
Total Scan time: 6.280 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]