Result of FASTA (ccds) for
pF1KB7327
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7327, 838 aa
1>>>pF1KB7327 838 - 838 aa - 838 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2226+/-0.00131; mu= 6.9603+/- 0.078
mean_var=177.7592+/-34.994, 0's: 0 Z-trim(105.8): 71 B-trim: 0 in 0/50
Lambda= 0.096196
statistics sampled from 8583 (8646) to 8583 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.266), width: 16
Scan time: 2.960
The best scores are: opt bits E(32554)
CCDS7434.1 HELLS gene_id:3070|Hs108|chr10 ( 838) 5499 776.7 0
CCDS73165.1 HELLS gene_id:3070|Hs108|chr10 ( 714) 4720 668.5 1.1e-191
CCDS73164.1 HELLS gene_id:3070|Hs108|chr10 ( 700) 4593 650.9 2.2e-186
CCDS73162.1 HELLS gene_id:3070|Hs108|chr10 ( 884) 2934 420.7 5.4e-117
CCDS73163.1 HELLS gene_id:3070|Hs108|chr10 ( 740) 2580 371.5 2.9e-102
CCDS76018.1 SMARCA1 gene_id:6594|Hs108|chrX (1058) 784 122.4 4.1e-27
CCDS3761.1 SMARCA5 gene_id:8467|Hs108|chr4 (1052) 770 120.5 1.6e-26
CCDS34204.1 CHD1 gene_id:1105|Hs108|chr5 (1710) 694 110.0 3.5e-23
CCDS10374.2 CHD2 gene_id:1106|Hs108|chr15 (1828) 694 110.1 3.7e-23
CCDS58914.1 SMARCAD1 gene_id:56916|Hs108|chr4 ( 596) 674 107.0 1e-22
CCDS3639.1 SMARCAD1 gene_id:56916|Hs108|chr4 (1026) 674 107.1 1.6e-22
CCDS47101.1 SMARCAD1 gene_id:56916|Hs108|chr4 (1028) 674 107.1 1.6e-22
CCDS72882.1 CHD1L gene_id:9557|Hs108|chr1 ( 797) 652 104.0 1.1e-21
CCDS927.1 CHD1L gene_id:9557|Hs108|chr1 ( 897) 652 104.0 1.2e-21
CCDS58021.1 CHD1L gene_id:9557|Hs108|chr1 ( 693) 649 103.5 1.3e-21
CCDS58022.1 CHD1L gene_id:9557|Hs108|chr1 ( 616) 648 103.4 1.3e-21
CCDS76510.1 CHD4 gene_id:1108|Hs108|chr12 (1905) 636 102.0 1e-20
CCDS8552.1 CHD4 gene_id:1108|Hs108|chr12 (1912) 636 102.0 1e-20
CCDS57.1 CHD5 gene_id:26038|Hs108|chr1 (1954) 630 101.2 1.8e-20
CCDS32555.1 CHD3 gene_id:1107|Hs108|chr17 (1966) 626 100.7 2.7e-20
CCDS32554.1 CHD3 gene_id:1107|Hs108|chr17 (2000) 626 100.7 2.7e-20
CCDS32553.2 CHD3 gene_id:1107|Hs108|chr17 (2059) 626 100.7 2.8e-20
CCDS83338.1 SMARCA2 gene_id:6595|Hs108|chr9 (1514) 619 99.6 4.3e-20
CCDS34978.1 SMARCA2 gene_id:6595|Hs108|chr9 (1572) 619 99.6 4.4e-20
CCDS34977.1 SMARCA2 gene_id:6595|Hs108|chr9 (1590) 619 99.6 4.5e-20
CCDS54218.1 SMARCA4 gene_id:6597|Hs108|chr19 (1613) 615 99.1 6.6e-20
CCDS54217.1 SMARCA4 gene_id:6597|Hs108|chr19 (1614) 615 99.1 6.6e-20
CCDS45973.1 SMARCA4 gene_id:6597|Hs108|chr19 (1616) 615 99.1 6.6e-20
CCDS45972.1 SMARCA4 gene_id:6597|Hs108|chr19 (1617) 615 99.1 6.6e-20
CCDS12253.1 SMARCA4 gene_id:6597|Hs108|chr19 (1647) 605 97.7 1.8e-19
CCDS10071.1 INO80 gene_id:54617|Hs108|chr15 (1556) 600 97.0 2.7e-19
CCDS13317.1 CHD6 gene_id:84181|Hs108|chr20 (2715) 592 96.0 9.1e-19
CCDS45485.1 CHD9 gene_id:80205|Hs108|chr16 (2881) 591 95.9 1.1e-18
CCDS76865.1 CHD9 gene_id:80205|Hs108|chr16 (2897) 591 95.9 1.1e-18
CCDS45081.1 CHD8 gene_id:57680|Hs108|chr14 (2302) 583 94.7 1.9e-18
CCDS53885.1 CHD8 gene_id:57680|Hs108|chr14 (2581) 583 94.8 2.1e-18
CCDS47865.1 CHD7 gene_id:55636|Hs108|chr8 (2997) 578 94.1 3.8e-18
CCDS10689.2 SRCAP gene_id:10847|Hs108|chr16 (3230) 526 86.9 6e-16
CCDS7229.1 ERCC6 gene_id:2074|Hs108|chr10 (1493) 492 82.0 8.6e-15
CCDS35329.1 ERCC6L gene_id:54821|Hs108|chrX (1250) 447 75.7 5.6e-13
CCDS14612.1 SMARCA1 gene_id:6594|Hs108|chrX (1054) 434 73.8 1.7e-12
CCDS76019.1 SMARCA1 gene_id:6594|Hs108|chrX (1070) 434 73.8 1.7e-12
CCDS35072.1 ERCC6L2 gene_id:375748|Hs108|chr9 ( 712) 427 72.7 2.5e-12
CCDS532.1 RAD54L gene_id:8438|Hs108|chr1 ( 747) 410 70.4 1.3e-11
CCDS75768.1 RAD54B gene_id:25788|Hs108|chr8 ( 726) 391 67.7 8e-11
CCDS7419.1 BTAF1 gene_id:9044|Hs108|chr10 (1849) 397 68.9 9.4e-11
CCDS6262.1 RAD54B gene_id:25788|Hs108|chr8 ( 910) 391 67.8 9.6e-11
>>CCDS7434.1 HELLS gene_id:3070|Hs108|chr10 (838 aa)
initn: 5499 init1: 5499 opt: 5499 Z-score: 4138.1 bits: 776.7 E(32554): 0
Smith-Waterman score: 5499; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KB7 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY
730 740 750 760 770 780
790 800 810 820 830
pF1KB7 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF
790 800 810 820 830
>>CCDS73165.1 HELLS gene_id:3070|Hs108|chr10 (714 aa)
initn: 4720 init1: 4720 opt: 4720 Z-score: 3554.8 bits: 668.5 E(32554): 1.1e-191
Smith-Waterman score: 4720; 100.0% identity (100.0% similar) in 714 aa overlap (125-838:1-714)
100 110 120 130 140 150
pF1KB7 KKKEKLERKKESLKVKKGKNSIDASEEKPVMRKKRGREDESYNISEVMSKEEILSVAKKN
::::::::::::::::::::::::::::::
CCDS73 MRKKRGREDESYNISEVMSKEEILSVAKKN
10 20 30
160 170 180 190 200 210
pF1KB7 KKENEDENSSSTNLCVEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 KKENEDENSSSTNLCVEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQ
40 50 60 70 80 90
220 230 240 250 260 270
pF1KB7 PKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 PKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPF
100 110 120 130 140 150
280 290 300 310 320 330
pF1KB7 LVCGPLSTLPNWMAEFKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LVCGPLSTLPNWMAEFKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFE
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB7 IAMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 IAMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELW
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB7 SLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKS
280 290 300 310 320 330
460 470 480 490 500 510
pF1KB7 DVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 DVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRK
340 350 360 370 380 390
520 530 540 550 560 570
pF1KB7 SINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHP
400 410 420 430 440 450
580 590 600 610 620 630
pF1KB7 YLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 YLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDY
460 470 480 490 500 510
640 650 660 670 680 690
pF1KB7 CHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 CHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDS
520 530 540 550 560 570
700 710 720 730 740 750
pF1KB7 DWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 DWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKG
580 590 600 610 620 630
760 770 780 790 800 810
pF1KB7 GQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASG
640 650 660 670 680 690
820 830
pF1KB7 PIKEKMGIFKILENSEDSSPECLF
::::::::::::::::::::::::
CCDS73 PIKEKMGIFKILENSEDSSPECLF
700 710
>>CCDS73164.1 HELLS gene_id:3070|Hs108|chr10 (700 aa)
initn: 4593 init1: 4593 opt: 4593 Z-score: 3459.6 bits: 650.9 E(32554): 2.2e-186
Smith-Waterman score: 4593; 99.3% identity (99.7% similar) in 699 aa overlap (140-838:2-700)
110 120 130 140 150 160
pF1KB7 KKGKNSIDASEEKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLC
.: ..::::::::::::::::::::::::
CCDS73 MQVKRSQEILSVAKKNKKENEDENSSSTNLC
10 20 30
170 180 190 200 210 220
pF1KB7 VEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 VEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVE
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB7 GMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAE
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB7 FKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 FKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWK
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB7 YLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 YLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLK
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB7 SFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVY
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB7 APLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 APLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELE
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB7 KLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 KLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFK
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB7 IDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 IDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSM
460 470 480 490 500 510
650 660 670 680 690 700
pF1KB7 SYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCH
520 530 540 550 560 570
710 720 730 740 750 760
pF1KB7 RIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPK
580 590 600 610 620 630
770 780 790 800 810 820
pF1KB7 ELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 ELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENS
640 650 660 670 680 690
830
pF1KB7 EDSSPECLF
:::::::::
CCDS73 EDSSPECLF
700
>>CCDS73162.1 HELLS gene_id:3070|Hs108|chr10 (884 aa)
initn: 2932 init1: 2932 opt: 2934 Z-score: 2213.9 bits: 420.7 E(32554): 5.4e-117
Smith-Waterman score: 5303; 94.7% identity (94.7% similar) in 870 aa overlap (1-824:1-870)
10 20 30 40 50 60
pF1KB7 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL
370 380 390 400 410 420
430 440
pF1KB7 SETAEDIIAKEREQNVLHMLHQ--------------------------------------
::::::::::::::::::::::
CCDS73 SETAEDIIAKEREQNVLHMLHQERIPRMYVSEFTDEGFFEGKLPSRKDLYDIRPYENTYL
430 440 450 460 470 480
450 460 470 480 490
pF1KB7 --------ILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LKLHTNFEILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGS
490 500 510 520 530 540
500 510 520 530 540 550
pF1KB7 SEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVES
550 560 570 580 590 600
560 570 580 590 600 610
pF1KB7 EVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 EVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKR
610 620 630 640 650 660
620 630 640 650 660 670
pF1KB7 GHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEVFIFLVST
670 680 690 700 710 720
680 690 700 710 720 730
pF1KB7 RAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVE
730 740 750 760 770 780
740 750 760 770 780 790
pF1KB7 RAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISD
790 800 810 820 830 840
800 810 820 830
pF1KB7 KDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF
::::::::::::::::::::::::::::::
CCDS73 KDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF
850 860 870 880
>>CCDS73163.1 HELLS gene_id:3070|Hs108|chr10 (740 aa)
initn: 2576 init1: 2576 opt: 2580 Z-score: 1949.5 bits: 371.5 E(32554): 2.9e-102
Smith-Waterman score: 4630; 88.3% identity (88.3% similar) in 838 aa overlap (1-838:1-740)
10 20 30 40 50 60
pF1KB7 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQLEAAGLERERKMLEKARMSWDRES
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 TEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 EKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNKDSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIK
::::::::::::::::::::::::::::::::::::::::::::
CCDS73 LYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQ----------------
310 320 330 340
370 380 390 400 410 420
pF1KB7 NMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSL
CCDS73 ------------------------------------------------------------
430 440 450 460 470 480
pF1KB7 SETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY
::::::::::::::::::::::::::::::::::::::
CCDS73 ----------------------ILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFY
350 360 370 380
490 500 510 520 530 540
pF1KB7 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 TAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVD
390 400 410 420 430 440
550 560 570 580 590 600
pF1KB7 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEELVTNSGK
450 460 470 480 490 500
610 620 630 640 650 660
pF1KB7 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 FLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHS
510 520 530 540 550 560
670 680 690 700 710 720
pF1KB7 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 FNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY
570 580 590 600 610 620
730 740 750 760 770 780
pF1KB7 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY
630 640 650 660 670 680
790 800 810 820 830
pF1KB7 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 EREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENSEDSSPECLF
690 700 710 720 730 740
>>CCDS76018.1 SMARCA1 gene_id:6594|Hs108|chrX (1058 aa)
initn: 1597 init1: 389 opt: 784 Z-score: 600.2 bits: 122.4 E(32554): 4.1e-27
Smith-Waterman score: 1526; 37.4% identity (66.2% similar) in 727 aa overlap (92-805:45-685)
70 80 90 100 110
pF1KB7 EIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKKE----SLKVKKGKNSID
: :: :.::: :...: . ..
CCDS76 ADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKNVSSFQLKLAAKAPK
20 30 40 50 60 70
120 130 140 150 160 170
pF1KB7 ASEEKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKKENEDENSSSTNLCVEDLQKNK
. .: ... . :.. . .... :.. :. . . .: :. . . .:
CCDS76 SEKEMDPEYEEKMKADRAKRFEFLLKQTELF--AHFIQPSAQKSPTSPLNMKLGRPRIKK
80 90 100 110 120 130
180 190 200 210 220 230
pF1KB7 D-SNSIIKD---RLSETVRQNTKFFFDPVRKCNGQPVPFQ-QPKHFTGGVMRWYQVEGME
: ..:.:. : .: ... . ... :: .. . :. .:.. :: .: ::..:..
CCDS76 DEKQSLISAGDYRHRRTEQEEDEELLSESRKTSNVCIRFEVSPSYVKGGPLRDYQIRGLN
140 150 160 170 180 190
240 250 260 270 280 290
pF1KB7 WLRMLWENGINGILADEMGLGKTVQCIATIALMIQ-RGVPGPFLVCGPLSTLPNWMAEFK
:: :.:::.:::::::::::::.: :: .. . . :..::: .: : ::: ::: :::
CCDS76 WLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFK
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB7 RFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYL
:..:.. .. . : .. : ..:. . : . : .::.:........... .:.::
CCDS76 RWVPSLRVICFVGDKDARAAFIRDEMM-PGEWD---VCVTSYEMVIKEKSVFKKFHWRYL
260 270 280 290 300
360 370 380 390 400 410
pF1KB7 IVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSF
..::.::::: : .: . ...:.. :.:::::::::::: :::.::::::::::.. .:
CCDS76 VIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDF
310 320 330 340 350 360
420 430 440 450 460 470
pF1KB7 ESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAP
.:::: ... .. .:.... :: .: ::::::.:.:: .:::.:. .:
CCDS76 DSWFD-------TKNCLG---DQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKEIKIYLG
370 380 390 400 410
480 490 500 510 520 530
pF1KB7 LSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKL
::: :. .:: :. . : ....:: .:.:
CCDS76 LSKMQREWYTKILMKDI-DVLNSS-----------------------GKMD---------
420 430 440
540 550 560 570 580
pF1KB7 ISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIE--YPIDPVTQEFK
...: ::.: ::::::::::.. : : :
CCDS76 -------------------------KMRLLNILMQLRKCCNHPYLFDGAEPGPPYTT---
450 460 470
590 600 610 620 630 640
pF1KB7 IDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSM
::..:.::::...::..: .::..: .::.::::: .:::: ::: : ... ::::.
CCDS76 -DEHIVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRLDGQT
480 490 500 510 520 530
650 660 670 680 690 700
pF1KB7 SYSEREKNMHSFNT-DPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRC
. :::. ...::. . :::..:::::::::::..::.::.:::::::: ::::.::
CCDS76 PHEEREEAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQAMDRA
540 550 560 570 580 590
710 720 730 740 750 760
pF1KB7 HRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDP
::::: ::: :.::.: ::....::::: : .:....:..... :: : :
CCDS76 HRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRLIDQQS------NKLAK
600 610 620 630 640 650
770 780 790 800 810 820
pF1KB7 KELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILEN
.:..... : .. .:.:. ..:.:. .:.:..
CCDS76 EEMLQMI--RHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGESSLRNFRM
660 670 680 690 700
830
pF1KB7 SEDSSPECLF
CCDS76 DIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEPKIPKAPRP
710 720 730 740 750 760
>>CCDS3761.1 SMARCA5 gene_id:8467|Hs108|chr4 (1052 aa)
initn: 1552 init1: 372 opt: 770 Z-score: 589.7 bits: 120.5 E(32554): 1.6e-26
Smith-Waterman score: 1489; 36.5% identity (62.2% similar) in 802 aa overlap (7-803:32-680)
10 20 30
pF1KB7 MPAERPAGSGGSEAPAMVEQLDTAVITPAMLEEEEQ
...:: :. : ..: :: : ::
CCDS37 SSAAEPPPPPPPESAPSKPAASIASGGSNSSNKGGPEGVAAQAVASAASAGPADAEMEEI
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB7 LEAAGLERERKMLEKARMSWDRESTEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKK
.. :. ..... : .. .:. : :...::........:. : ::
CCDS37 FDDASPGKQKEIQEPDPTYEEKMQTD-RANRFEYLLKQTELFAHFI-------QPAAQKT
70 80 90 100 110
100 110 120 130 140 150
pF1KB7 KEKLERKKESLKVKKGKNSIDASEEKPVMRKKRGREDESYNISEVMSKEEILSVAKKNKK
. ::.: :. : .:.. .. . : : . .: ::.:.
CCDS37 PTS------PLKMKPGRPRIKKDEKQNLL--SVG--DYRHRRTEQEEDEELLT-------
120 130 140 150
160 170 180 190 200 210
pF1KB7 ENEDENSSSTNLCVEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPK
:.:..::.:. . .:: : .:
CCDS37 ----ESSKATNVCT----RFEDSPSYVK--------------------------------
160 170
220 230 240 250 260 270
pF1KB7 HFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQ-RGVPGPFL
: .: :::.:..:: :.:::::::::::::::::.: :. .. : . :..::: .
CCDS37 ---WGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHM
180 190 200 210 220 230
280 290 300 310 320 330
pF1KB7 VCGPLSTLPNWMAEFKRFTPDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEI
: : ::: :::.::::..: . .. : .:.: .::.. : . : .::.:.
CCDS37 VLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLL-PGEWD---VCVTSYEM
240 250 260 270 280
340 350 360 370 380 390
pF1KB7 AMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWS
......... :.::..::.::::: : .: . ...:.. :.:::::::::::: ::::
CCDS37 LIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWS
290 300 310 320 330 340
400 410 420 430 440 450
pF1KB7 LLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSD
::::::::::.. .:.:::: ... .. .:.... ::..: ::::::.:.:
CCDS37 LLNFLLPDVFNSADDFDSWFD-------TNNCLG---DQKLVERLHMVLRPFLLRRIKAD
350 360 370 380 390
460 470 480 490 500 510
pF1KB7 VALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKS
: .:::.:: .:. ::: :. .:: :. . : ....:.
CCDS37 VEKSLPPKKEVKIYVGLSKMQREWYTRILMKDI-DILNSA--------------------
400 410 420 430
520 530 540 550 560 570
pF1KB7 INYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPY
.:.: ...: ::.: :::::::::
CCDS37 ---GKMD----------------------------------KMRLLNILMQLRKCCNHPY
440 450 460
580 590 600 610 620 630
pF1KB7 LIE--YPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMD
:.. : : : : .:::::::...::..::.::..: .::.::::: .:::: :
CCDS37 LFDGAEPGPPYTT----DMHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILED
470 480 490 500 510
640 650 660 670 680 690
pF1KB7 YCHLRDFNFSRLDGSMSYSEREKNMHSFNTDPEV--FIFLVSTRAGGLGINLTAADTVII
:: :.... ::::. ..::. .....: .:. :.:..:::::::::::..::.::.
CCDS37 YCMWRNYEYCRLDGQTPHDERQDSINAYN-EPNSTKFVFMLSTRAGGLGINLATADVVIL
520 530 540 550 560 570
700 710 720 730 740 750
pF1KB7 YDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNH
:::::::: ::::.:: ::::::: : :.:..: ::....::::: : .:....:..
CCDS37 YDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQ--
580 590 600 610 620 630
760 770 780 790 800 810
pF1KB7 FKGGQSGLNLSKNFLDPKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMN
: ::.: . :..... : .. .:.:. :.:.:.. .:.:
CCDS37 --GRLVDQNLNK--IGKDEMLQMI--RHGATHVFASKESEITDEDIDGILERGAKKTAEM
640 650 660 670 680
820 830
pF1KB7 ASGPIKEKMGIFKILENSEDSSPECLF
CCDS37 NEKLSKMGESSLRNFTMDTESSVYNFEGEDYREKQKIAFTEWIEPPKRERKANYAVDAYF
690 700 710 720 730 740
>>CCDS34204.1 CHD1 gene_id:1105|Hs108|chr5 (1710 aa)
initn: 1149 init1: 329 opt: 694 Z-score: 529.7 bits: 110.0 E(32554): 3.5e-23
Smith-Waterman score: 1150; 32.3% identity (59.1% similar) in 792 aa overlap (57-825:310-1021)
30 40 50 60 70 80
pF1KB7 TPAMLEEEEQLEAAGLERERKMLEKARMSWDRESTEIRYRRLQHLLEKSNIYSKFLLTK-
..: ::.: : . :.:.. . .
CCDS34 CRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQY--LIKWKGWSHIHNTWETEET
280 290 300 310 320 330
90 100 110 120 130 140
pF1KB7 MEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASEEKPVMRKKRGREDESYNISE-VMSK
..::... .:: .. ..: . : . : . : ... ..:.: : ....
CCDS34 LKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAH
340 350 360 370 380 390
150 160 170 180 190 200
pF1KB7 EEILSVAKKNKKENEDENSSSTNLCVED-LQKNKDSNSIIKDRLSETVRQNTKFFFDPVR
. :.: . .. .. :: .: .. : . .:.. ..: : :
CCDS34 SNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVL
400 410 420 430 440 450
210 220 230 240 250
pF1KB7 KCNGQPVPFQQPKHFTGG----VMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCI
: . : ... . :: .: ::..:..:: : .: . :::::::::::.: :
CCDS34 KQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTI
460 470 480 490 500 510
260 270 280 290 300 310
pF1KB7 ATIALMI-QRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTMLYHGTQEERQKLVRNIYK
. . .. .. . ::::. ::::: .:. :.. .. .. ...: : . :. . . .
CCDS34 SFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWT
520 530 540 550 560 570
320 330 340 350 360 370
pF1KB7 RKGTLQIH-PVVITSFEIAMRDRNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADN
.. : ... ...:..:: ..:. : : .. :::.::.:: : . : :....
CCDS34 HHQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNH
580 590 600 610 620 630
380 390 400 410 420 430
pF1KB7 KLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVL
.::.:::::::.:.::::::.:..:. .: :: :. :. .: :: .
CCDS34 RLLITGTPLQNSLKELWSLLHFIMPE------KFSSWEDF-------EEEHGKGREYGYA
640 650 660 670 680
440 450 460 470 480 490
pF1KB7 HMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEK
::. : ::::::.:.:: .: : : .. .: :. .: :..:. . .:.
CCDS34 S-LHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKG
690 700 710 720 730 740
500 510 520 530 540 550
pF1KB7 ETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVN
: .:
CCDS34 ST-----SG---------------------------------------------------
560 570 580 590 600 610
pF1KB7 LKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFKIDEE----LVTNSGKFLILDRMLPELKK
. :::: :.::::: :::. : : ..:: .: :. .:::...::..: .:..
CCDS34 --FLNIMMELKKCCNHCYLIK-P--PDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRE
750 760 770 780 790 800
620 630 640 650 660 670
pF1KB7 RGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKNMHSFNTD-PEVFIFLV
::..::.::::. ::::: .: . :.: :.:::::.. :.. . ::.. : : ::.
CCDS34 RGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLL
810 820 830 840 850 860
680 690 700 710 720 730
pF1KB7 STRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKI
:::::::::::..::::.:.:::::::.::::: : ::::: : : .::::: ..... :
CCDS34 STRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDI
870 880 890 900 910 920
740 750 760 770 780
pF1KB7 VERAAAKRKLEKLIIHKNHFKGG---QSGLNLSKNF-LDPKELMELLK--SRDYEREIKG
.::: : :..:.:.. : ..: :.. .. .:: .:: ... .: .:
CCDS34 LERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEG
930 940 950 960 970 980
790 800 810 820 830
pF1KB7 SREKVISDKDLELLLDRSDLIDQMNASGPIK---EKMGIFKILENSEDSSPECLF
.:. .. :.. .: :.. . : ::. : .. ::.
CCDS34 -EEQEPQEMDIDEILKRAET--HENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERN
990 1000 1010 1020 1030
CCDS34 SKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSD
1040 1050 1060 1070 1080 1090
>>CCDS10374.2 CHD2 gene_id:1106|Hs108|chr15 (1828 aa)
initn: 1084 init1: 337 opt: 694 Z-score: 529.3 bits: 110.1 E(32554): 3.7e-23
Smith-Waterman score: 1228; 32.9% identity (61.2% similar) in 806 aa overlap (56-825:296-1023)
30 40 50 60 70 80
pF1KB7 ITPAMLEEEEQLEAAGLERERKMLEKARMSWDRESTEIRYRRLQHLLEKSNIYSKFLLTK
.: :. : . . : . : :.: . .
CCDS10 VLDSRLGKKGATGASTTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEE
270 280 290 300 310 320
90 100 110 120 130 140
pF1KB7 -MEQQQLEEQKKKEKLERKKESLKVKKGKNSIDASEEKPVMRKKRGREDESYNISE-VMS
..::... :: :....:.. .: :: : . : ... .. ...:.: : :..
CCDS10 SLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDVEYFNCQQELASELNKQYQIVERVIA
330 340 350 360 370 380
150 160 170 180 190
pF1KB7 KEEILSVAKKNKKENEDENSSSTN----LC----VEDLQKNKDSNSIIKDRLSETV----
. :. .. .... . .: :: . . . .....: .... .
CCDS10 VKTSKSTLGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFH
390 400 410 420 430 440
200 210 220 230 240
pF1KB7 -RQNTKFFFDPVRKCNG---QP--VPFQQPKHFTGGV---MRWYQVEGMEWLRMLWENGI
:.:.: . :.:.:.. .: : ... . :: .: ::.::..:: : ..
CCDS10 SRNNSKTI--PTRECKALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSWCKNN
450 460 470 480 490 500
250 260 270 280 290 300
pF1KB7 NGILADEMGLGKTVQCIATIALMI-QRGVPGPFLVCGPLSTLPNWMAEFKRFTPDIPTML
. :::::::::::.: :. .. .. :. . ::::. ::::: .:. ::. ..:.: ...
CCDS10 SVILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVV
510 520 530 540 550 560
310 320 330 340 350
pF1KB7 YHGTQEERQKLVRN---IYKRKGTLQIHPVVITSFEIAMRDRNALQHCYWKYLIVDEGHR
: : :. .:. :... :... ..::..:: ..:...: : .: :::.::
CCDS10 YIGDLMSRNT-IREYEWIHSQTKRLKFN-ALITTYEILLKDKTVLGSINWAFLGVDEAHR
570 580 590 600 610 620
360 370 380 390 400 410
pF1KB7 IKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDIT
.:: : . : :.....::.:::::::.:.::::::.:..:. .:: : :.
CCDS10 LKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPE------KFEFWEDF-
630 640 650 660 670
420 430 440 450 460 470
pF1KB7 SLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLSKKQEI
:. .: :: : . ::..: ::::::.:.:: .: : : .. . .: :.
CCDS10 ------EEDHGKGRE-NGYQSLHKVLEPFLLRRVKKDVEKSLPAKVEQILRVEMSALQKQ
680 690 700 710 720
480 490 500 510 520 530
pF1KB7 FYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNELEKLISQIQPE
.: :..:. . . :: : .
CCDS10 YYKWILTRNYKAL-----------------AKGTRGSTS---------------------
730 740
540 550 560 570 580 590
pF1KB7 VDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQEFK-IDEELVTN
. ::.: :.::::: :::. : . .. . : :. .
CCDS10 --------------------GFLNIVMELKKCCNHCYLIKPPEENERENGQEILLSLIRS
750 760 770 780
600 610 620 630 640 650
pF1KB7 SGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSMSYSEREKN
:::...::..: .:..::..::.::::. ::::: .: .. . :.:::::.. :..
CCDS10 SGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQA
790 800 810 820 830 840
660 670 680 690 700 710
pF1KB7 MHSFNTD-PEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKP
. ::.: : : ::.:::::::::::..::::.:.:::::::.::::: : ::::: :
CCDS10 LDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQ
850 860 870 880 890 900
720 730 740 750 760 770
pF1KB7 VVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKG-----GQSGLNLSKNFLDPKEL
: .::::: .:....:.::: : :..:.:.. : ..:: . :. : . .::
CCDS10 VNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRTILENNSGRSNSNPF-NKEEL
910 920 930 940 950 960
780 790 800 810 820
pF1KB7 MELLK--SRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILENS
.:: ..: .:..: .:. .. :.. .: .. .. ... : .. ::.
CCDS10 TAILKFGAEDLFKELEG-EESEPQEMDIDEILRLAETRENEVSTSATDELLSQFKVANFA
970 980 990 1000 1010 1020
830
pF1KB7 EDSSPECLF
CCDS10 TMEDEEELEERPHKDWDEIIPEEQRKKVEEEERQKELEEIYMLPRIRSSTKKAQTNDSDS
1030 1040 1050 1060 1070 1080
>>CCDS58914.1 SMARCAD1 gene_id:56916|Hs108|chr4 (596 aa)
initn: 1134 init1: 506 opt: 674 Z-score: 521.2 bits: 107.0 E(32554): 1e-22
Smith-Waterman score: 1137; 37.5% identity (66.5% similar) in 547 aa overlap (206-744:49-569)
180 190 200 210 220 230
pF1KB7 NKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGV-MRWYQVEGMEWL
:: ..::. .. .. .. :: :..::
CCDS58 IQERDVVIRLMNKCEDISNKLTKQVTMLTGNGGGWNIEQPSILNQSLSLKPYQKVGLNWL
20 30 40 50 60 70
240 250 260 270 280 290
pF1KB7 RMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFT
.. ..:.:::::::::::::.: :: .: . :.: :: :. : ::. ::. : . .
CCDS58 ALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEGNNGPHLIVVPASTIDNWLREVNLWC
80 90 100 110 120 130
300 310 320 330 340 350
pF1KB7 PDIPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMR---DRNALQHCYWKYL
: . .. :.:.::::... ::..: . . :..:... :. ::. ... .:
CCDS58 PTLKVLCYYGSQEERKQIRFNIHSR---YEDYNVIVTTYNCAISSSDDRSLFRRLKLNYA
140 150 160 170 180 190
360 370 380 390 400 410
pF1KB7 IVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKS-
: :::: .::: ..: .::.:.:::::::.:::: :: :::::..: .:.. :
CCDS58 IFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSSTSE
200 210 220 230 240 250
420 430 440 450 460 470
pF1KB7 FESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYA
.. :. . : ..: ::: . : .::. ::.:::.: .: ..:::.. .
CCDS58 IRRMFSSKTKSADEQSIYEKER---IAHA-KQIIKPFILRRVKEEVLKQLPPKKDRIELC
260 270 280 290 300 310
480 490 500 510 520
pF1KB7 PLSKKQEIFYTAIVNR---TIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDDFPNE
.:.::: .: .. :: .: :. ..: .. . . :: :. .
CCDS58 AMSEKQEQLYLGLFNRLKKSINNLEKNTEMCNVMM--------QLRKMANHPLLHRQYYT
320 330 340 350 360
530 540 550 560 570 580
pF1KB7 LEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLLRKCCNHPYLIEYPIDPVTQE
::: .... . .: . :.: . : ...... . : : .. .. ..
CCDS58 AEKL-KEMSQLMLKEPTHCEANPDLIFE-DMEVMTDFELHVLCKQYRHI---------NN
370 380 390 400 410
590 600 610 620 630 640
pF1KB7 FKIDEELVTNSGKFLILDRMLPELKKRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDG
:..: .:. .:::: .: .: :::..: .:.::::.: ::::: . .. . ::::
CCDS58 FQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHRYLRLDG
420 430 440 450 460 470
650 660 670 680 690 700
pF1KB7 SMSYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDR
. . ::: . . :::: ..:.::.::.:::::::::.:..::..: : :: .: ::.::
CCDS58 KTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDR
480 490 500 510 520 530
710 720 730 740 750 760
pF1KB7 CHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLD
:::.:::: :.: .:.. .::...... : :::.
CCDS58 CHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQDMTTVDEGDEGSMPADIATLLKT
540 550 560 570 580 590
770 780 790 800 810 820
pF1KB7 PKELMELLKSRDYEREIKGSREKVISDKDLELLLDRSDLIDQMNASGPIKEKMGIFKILE
CCDS58 SMGL
838 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:41:45 2016 done: Sat Nov 5 08:41:45 2016
Total Scan time: 2.960 Total Display time: 0.240
Function used was FASTA [36.3.4 Apr, 2011]