Result of FASTA (omim) for
pF1KB7185
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7185, 444 aa
1>>>pF1KB7185 444 - 444 aa - 444 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.5364+/-0.00041; mu= 22.8713+/- 0.026
mean_var=111.4595+/-27.306, 0's: 0 Z-trim(113.3): 635 B-trim: 1263 in 1/51
Lambda= 0.121483
statistics sampled from 21804 (22601) to 21804 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.265), width: 16
Scan time: 8.710
The best scores are: opt bits E(85289)
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 3006 538.3 1.5e-152
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 3006 538.3 1.5e-152
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 1892 343.1 8.7e-94
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 1892 343.1 8.7e-94
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 1892 343.1 8.7e-94
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 1746 317.4 4.2e-86
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 530 104.3 6.2e-22
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 530 104.3 6.2e-22
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 530 104.5 7e-22
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 491 97.5 7.2e-20
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 475 94.7 5e-19
NP_000785 (OMIM: 126449) D(1A) dopamine receptor [ ( 446) 450 90.4 1.1e-17
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 438 88.2 4.5e-17
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 429 86.6 1.2e-16
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 422 85.3 2.9e-16
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 422 85.3 2.9e-16
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 422 85.3 2.9e-16
NP_000670 (OMIM: 104220) alpha-1B adrenergic recep ( 520) 418 84.8 5.7e-16
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 415 84.1 6.9e-16
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 415 84.1 6.9e-16
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 406 82.6 2.1e-15
NP_056542 (OMIM: 162323) substance-P receptor isof ( 311) 399 81.2 4.3e-15
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 400 81.5 4.3e-15
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407) 399 81.4 5e-15
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 397 80.9 5.8e-15
XP_005253267 (OMIM: 118445) PREDICTED: gastrin/cho ( 516) 398 81.3 6.4e-15
NP_795344 (OMIM: 118445) gastrin/cholecystokinin t ( 447) 397 81.1 6.7e-15
NP_001304021 (OMIM: 602001) neuropeptide Y recepto ( 445) 395 80.7 8.5e-15
NP_001304020 (OMIM: 602001) neuropeptide Y recepto ( 445) 395 80.7 8.5e-15
XP_011530319 (OMIM: 602001) PREDICTED: neuropeptid ( 445) 395 80.7 8.5e-15
XP_005263095 (OMIM: 602001) PREDICTED: neuropeptid ( 445) 395 80.7 8.5e-15
NP_006165 (OMIM: 602001) neuropeptide Y receptor t ( 445) 395 80.7 8.5e-15
XP_016863744 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 395 80.7 8.6e-15
XP_011530317 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 395 80.7 8.6e-15
XP_016863745 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 395 80.7 8.6e-15
NP_000669 (OMIM: 104219) alpha-1D adrenergic recep ( 572) 394 80.7 1.1e-14
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375) 389 79.6 1.6e-14
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 389 79.6 1.6e-14
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 389 79.6 1.6e-14
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375) 389 79.6 1.6e-14
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 389 79.6 1.6e-14
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 389 79.6 1.6e-14
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 381 78.2 4.3e-14
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 381 78.2 4.3e-14
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 381 78.2 4.3e-14
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 377 77.5 7e-14
NP_000721 (OMIM: 118444) cholecystokinin receptor ( 428) 377 77.5 7.4e-14
XP_016864182 (OMIM: 606925) PREDICTED: pyroglutamy ( 190) 372 76.1 8.7e-14
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 373 76.9 1.3e-13
XP_016874005 (OMIM: 118445) PREDICTED: gastrin/cho ( 381) 371 76.4 1.4e-13
>>NP_001517 (OMIM: 602393) orexin receptor type 2 [Homo (444 aa)
initn: 3006 init1: 3006 opt: 3006 Z-score: 2859.8 bits: 538.3 E(85289): 1.5e-152
Smith-Waterman score: 3006; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444)
10 20 30 40 50 60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
370 380 390 400 410 420
430 440
pF1KB7 SEQVVLTSISTLPAANGAGPLQNW
::::::::::::::::::::::::
NP_001 SEQVVLTSISTLPAANGAGPLQNW
430 440
>>XP_016866287 (OMIM: 602393) PREDICTED: orexin receptor (461 aa)
initn: 3006 init1: 3006 opt: 3006 Z-score: 2859.6 bits: 538.3 E(85289): 1.5e-152
Smith-Waterman score: 3006; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444)
10 20 30 40 50 60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
370 380 390 400 410 420
430 440
pF1KB7 SEQVVLTSISTLPAANGAGPLQNW
::::::::::::::::::::::::
XP_016 SEQVVLTSISTLPAANGAGPLQNWCLQQGPPSSLPSTWLDV
430 440 450 460
>>XP_016856595 (OMIM: 602392) PREDICTED: orexin receptor (425 aa)
initn: 1853 init1: 1261 opt: 1892 Z-score: 1804.8 bits: 343.1 E(85289): 8.7e-94
Smith-Waterman score: 1892; 69.2% identity (85.6% similar) in 416 aa overlap (24-433:17-425)
10 20 30 40 50 60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
..:: : ::.:: :::::::.::.::.:::::::.
XP_016 MEPSATPGAQMGVPPGSREPSPVPPDYEDE-FLRYLWRDYLYPKQYEWVLIAA
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
:. ::::::.::.:::.:::.::::::::::::::::::::::: ::::.:.:::::.:
XP_016 YVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESW
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
.::..:::::::::.:::::.::::: :::::::::::::.:::::.:::.::. :: ::
XP_016 LFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
::.::: :::::.:.: :::.: ::.::::::. ..:::.:: :::.:::.::: ::.
XP_016 LAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMA
180 190 200 210 220 230
250 260 270 280 290
pF1KB7 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQ----PRG-PGQPTKSRMSAVAAEIKQ
.::.::::::: ::::::.:.. :.:: .: .: .: :.: . : : ::.::
XP_016 MAYFQIFRKLWGRQIPGTTSALVRNWK--RPSDQLGDLEQGLSGEP-QPRARAFLAEVKQ
240 250 260 270 280
300 310 320 330 340 350
pF1KB7 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
.:::::::.:::.::::::.::::::.::::::::::: .. :::.::: ::::::::::
XP_016 MRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYA
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB7 NSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFD
::::::::::::::::::.:::::::: :. . :.:. :.:::. :
XP_016 NSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSA-SHKSLSLQSRC--
350 360 370 380 390 400
420 430 440
pF1KB7 NISKLSEQVVLTSIST-LPAANGAGPLQNW
.:::.::.:::::..: ::
XP_016 SISKISEHVVLTSVTTVLP
410 420
>>XP_016856594 (OMIM: 602392) PREDICTED: orexin receptor (425 aa)
initn: 1853 init1: 1261 opt: 1892 Z-score: 1804.8 bits: 343.1 E(85289): 8.7e-94
Smith-Waterman score: 1892; 69.2% identity (85.6% similar) in 416 aa overlap (24-433:17-425)
10 20 30 40 50 60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
..:: : ::.:: :::::::.::.::.:::::::.
XP_016 MEPSATPGAQMGVPPGSREPSPVPPDYEDE-FLRYLWRDYLYPKQYEWVLIAA
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
:. ::::::.::.:::.:::.::::::::::::::::::::::: ::::.:.:::::.:
XP_016 YVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESW
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
.::..:::::::::.:::::.::::: :::::::::::::.:::::.:::.::. :: ::
XP_016 LFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
::.::: :::::.:.: :::.: ::.::::::. ..:::.:: :::.:::.::: ::.
XP_016 LAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMA
180 190 200 210 220 230
250 260 270 280 290
pF1KB7 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQ----PRG-PGQPTKSRMSAVAAEIKQ
.::.::::::: ::::::.:.. :.:: .: .: .: :.: . : : ::.::
XP_016 MAYFQIFRKLWGRQIPGTTSALVRNWK--RPSDQLGDLEQGLSGEP-QPRARAFLAEVKQ
240 250 260 270 280
300 310 320 330 340 350
pF1KB7 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
.:::::::.:::.::::::.::::::.::::::::::: .. :::.::: ::::::::::
XP_016 MRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYA
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB7 NSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFD
::::::::::::::::::.:::::::: :. . :.:. :.:::. :
XP_016 NSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSA-SHKSLSLQSRC--
350 360 370 380 390 400
420 430 440
pF1KB7 NISKLSEQVVLTSIST-LPAANGAGPLQNW
.:::.::.:::::..: ::
XP_016 SISKISEHVVLTSVTTVLP
410 420
>>NP_001516 (OMIM: 602392) orexin receptor type 1 [Homo (425 aa)
initn: 1853 init1: 1261 opt: 1892 Z-score: 1804.8 bits: 343.1 E(85289): 8.7e-94
Smith-Waterman score: 1892; 69.2% identity (85.6% similar) in 416 aa overlap (24-433:17-425)
10 20 30 40 50 60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
..:: : ::.:: :::::::.::.::.:::::::.
NP_001 MEPSATPGAQMGVPPGSREPSPVPPDYEDE-FLRYLWRDYLYPKQYEWVLIAA
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
:. ::::::.::.:::.:::.::::::::::::::::::::::: ::::.:.:::::.:
NP_001 YVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESW
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
.::..:::::::::.:::::.::::: :::::::::::::.:::::.:::.::. :: ::
NP_001 LFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
::.::: :::::.:.: :::.: ::.::::::. ..:::.:: :::.:::.::: ::.
NP_001 LAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMA
180 190 200 210 220 230
250 260 270 280 290
pF1KB7 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQ----PRG-PGQPTKSRMSAVAAEIKQ
.::.::::::: ::::::.:.. :.:: .: .: .: :.: . : : ::.::
NP_001 MAYFQIFRKLWGRQIPGTTSALVRNWK--RPSDQLGDLEQGLSGEP-QPRARAFLAEVKQ
240 250 260 270 280
300 310 320 330 340 350
pF1KB7 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
.:::::::.:::.::::::.::::::.::::::::::: .. :::.::: ::::::::::
NP_001 MRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYA
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB7 NSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFD
::::::::::::::::::.:::::::: :. . :.:. :.:::. :
NP_001 NSAANPIIYNFLSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSA-SHKSLSLQSRC--
350 360 370 380 390 400
420 430 440
pF1KB7 NISKLSEQVVLTSIST-LPAANGAGPLQNW
.:::.::.:::::..: ::
NP_001 SISKISEHVVLTSVTTVLP
410 420
>>XP_016856596 (OMIM: 602392) PREDICTED: orexin receptor (389 aa)
initn: 1705 init1: 1261 opt: 1746 Z-score: 1666.9 bits: 317.4 E(85289): 4.2e-86
Smith-Waterman score: 1746; 70.9% identity (87.0% similar) in 368 aa overlap (24-385:17-378)
10 20 30 40 50 60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
..:: : ::.:: :::::::.::.::.:::::::.
XP_016 MEPSATPGAQMGVPPGSREPSPVPPDYEDE-FLRYLWRDYLYPKQYEWVLIAA
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
:. ::::::.::.:::.:::.::::::::::::::::::::::: ::::.:.:::::.:
XP_016 YVAVFVVALVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESW
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
.::..:::::::::.:::::.::::: :::::::::::::.:::::.:::.::. :: ::
XP_016 LFGHALCKVIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVS
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
::.::: :::::.:.: :::.: ::.::::::. ..:::.:: :::.:::.::: ::.
XP_016 LAIMVPQAAVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMA
180 190 200 210 220 230
250 260 270 280 290
pF1KB7 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQ----PRG-PGQPTKSRMSAVAAEIKQ
.::.::::::: ::::::.:.. :.:: .: .: .: :.: . : : ::.::
XP_016 MAYFQIFRKLWGRQIPGTTSALVRNWK--RPSDQLGDLEQGLSGEP-QPRARAFLAEVKQ
240 250 260 270 280
300 310 320 330 340 350
pF1KB7 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
.:::::::.:::.::::::.::::::.::::::::::: .. :::.::: ::::::::::
XP_016 MRARRKTAKMLMVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYA
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB7 NSAANPIIYNFLSGKFREEFKAAFSC-CCLGVHHRQEDRLTRGRTSTESRKSLTTQISNF
:::::::::::::: .: . :.:: : :
XP_016 NSAANPIIYNFLSGC--KEKSLALSCPSCPGHDPHLAAALCS
350 360 370 380
420 430 440
pF1KB7 DNISKLSEQVVLTSISTLPAANGAGPLQNW
>>NP_444264 (OMIM: 607449) neuropeptide FF receptor 2 is (420 aa)
initn: 605 init1: 419 opt: 530 Z-score: 514.8 bits: 104.3 E(85289): 6.2e-22
Smith-Waterman score: 658; 32.1% identity (59.9% similar) in 377 aa overlap (8-379:6-348)
10 20 30 40 50 60
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
:. .:: ..:.:.. . . . .. : ::: . ..: .
NP_444 MNEKWDTNSSENWHPIWNVNDTKHHLYSDINIT---YVNY----YLHQPQVAAIFIIS
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
:...: . ..::..:: : .:.::.:::: ::.::...:.:: : :.: ::. .: :
NP_444 YFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGW
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
::...::. .: .::..::.:: ::.::. . .:. : : : : :.:::...
NP_444 PFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLA
120 130 140 150 160 170
190 200 210 220 230
pF1KB7 CIIMIPQAIVMECST-----VFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAP
:: :.:.... . : . :::. : : : .. . :.: .: :.::
NP_444 ITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 LCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQ
: :.:. : .: .:. .: :. :..: . ::
NP_444 LSLIVIMYGRIGISLFRAAVPHTGRKNQEQW---HVVS----------------------
240 250 260
300 310 320 330 340 350
pF1KB7 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
: ..: .::.:: :.: . .::. : .:. . . . ..: . :.:::...
NP_444 -RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYI-YPFAHWLAFG
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB7 NSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFD
::..:::::.:.. .::. :. ::
NP_444 NSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQEST
330 340 350 360 370 380
>>NP_001138228 (OMIM: 607449) neuropeptide FF receptor 2 (423 aa)
initn: 605 init1: 419 opt: 530 Z-score: 514.7 bits: 104.3 E(85289): 6.2e-22
Smith-Waterman score: 658; 32.1% identity (59.9% similar) in 377 aa overlap (8-379:9-351)
10 20 30 40 50
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIA
:. .:: ..:.:.. . . . .. : ::: . ..:
NP_001 MFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINIT---YVNY----YLHQPQVAAIFII
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 GYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITET
.:...: . ..::..:: : .:.::.:::: ::.::...:.:: : :.: ::. .:
NP_001 SYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 WFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIV
: ::...::. .: .::..::.:: ::.::. . .:. : : : : :.:::..
NP_001 WPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 SCIIMIPQAIVMECST-----VFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMA
. :: :.:.... . : . :::. : : : .. . :.: .: :.:
NP_001 AITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 PLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIK
:: :.:. : .: .:. .: :. :..: . ::
NP_001 PLSLIVIMYGRIGISLFRAAVPHTGRKNQEQW---HVVS---------------------
240 250 260
300 310 320 330 340 350
pF1KB7 QIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVY
: ..: .::.:: :.: . .::. : .:. . . . ..: . :.:::..
NP_001 --RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYI-YPFAHWLAF
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB7 ANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNF
.::..:::::.:.. .::. :. ::
NP_001 GNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQES
330 340 350 360 370 380
>>NP_004876 (OMIM: 607449) neuropeptide FF receptor 2 is (522 aa)
initn: 605 init1: 419 opt: 530 Z-score: 513.8 bits: 104.5 E(85289): 7e-22
Smith-Waterman score: 658; 32.1% identity (59.9% similar) in 377 aa overlap (8-379:108-450)
10 20 30
pF1KB7 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDE
:. .:: ..:.:.. . . .
NP_004 RTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINIT--
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB7 EFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLS
.. : ::: . ..: .:...: . ..::..:: : .:.::.:::: ::.::.
NP_004 -YVNY----YLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLA
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB7 LADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAIC
..:.:: : :.: ::. .: : ::...::. .: .::..::.:: ::.::. .
NP_004 ISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVV
200 210 220 230 240 250
160 170 180 190 200 210
pF1KB7 HPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECST-----VFPGLANKTTLFTVCDE
.:. : : : : :.:::... :: :.:.... . : . :::. : :
NP_004 YPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCRE
260 270 280 290 300 310
220 230 240 250 260 270
pF1KB7 RWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPV
: .. . :.: .: :.::: :.:. : .: .:. .: :. :..: . :
NP_004 DWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQW---HVV
320 330 340 350 360
280 290 300 310 320 330
pF1KB7 SQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGM
: : ..: .::.:: :.: . .::. : .:. .
NP_004 S-----------------------RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADL
370 380 390 400
340 350 360 370 380 390
pF1KB7 FAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQED
. . ..: . :.:::...::..:::::.:.. .::. :. ::
NP_004 SPNELQIINIYI-YPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPME
410 420 430 440 450 460
400 410 420 430 440
pF1KB7 RLTRGRTSTESRKSLTTQISNFDNISKLSEQVVLTSISTLPAANGAGPLQNW
NP_004 AYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
470 480 490 500 510 520
>>NP_071429 (OMIM: 607448) neuropeptide FF receptor 1 [H (430 aa)
initn: 583 init1: 399 opt: 491 Z-score: 477.7 bits: 97.5 E(85289): 7.2e-20
Smith-Waterman score: 652; 34.9% identity (58.7% similar) in 375 aa overlap (10-379:8-344)
10 20 30 40 50
pF1KB7 MSGTKLEDSPPCRNWS-SASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIA
:: .: : . : : : : : : : : . ..:.
NP_071 MEGEPSQPPNSSWPLSQNGTNTEATPATNLT------FSSY----YQHTSPVAAMFIV
10 20 30 40
60 70 80 90 100 110
pF1KB7 GYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITET
.: ..:.. ..::.::: : ::.::.::::.::.::...:.:: : :.:.::: ..
NP_071 AYALIFLLCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB7 WFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIV
: : .. ::. .: .:::.::.:: ::..:. : ::. : : ..: .:..:: .
NP_071 WPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALVTIAVIWAL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB7 SCIIMIPQAIVM----ECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAP
. .:: :.:... : . :.. . : : : . . ..: .: :.::
NP_071 ALLIMCPSAVTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAP
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB7 LCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQ
: :.:. : .: ::: : : :: . :: . ::. .
NP_071 LALIVVMYARIARKL-C-QAPGPA------------------PG-------GEEAADPRA
230 240 250 260
300 310 320 330 340 350
pF1KB7 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYA
: : ....::..: : :.. .::. : .: . : :::: : :.:::..
NP_071 SRRRARVVHMLVMVALFFTLSWLPLWALLLLIDYGQLSAPQLHLVTVYA-FPFAHWLAFF
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB7 NSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFD
::.::::::.... .::. :.:::
NP_071 NSSANPIIYGYFNENFRRGFQAAFRARLCPRPSGSHKEAYSERPGGLLHRRVFVVVRPSD
330 340 350 360 370 380
444 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 05:41:05 2016 done: Fri Nov 4 05:41:06 2016
Total Scan time: 8.710 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]