Result of FASTA (omim) for
pF1KB7038
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7038, 457 aa
1>>>pF1KB7038 457 - 457 aa - 457 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.5451+/-0.000373; mu= 1.3451+/- 0.023
mean_var=284.0966+/-60.097, 0's: 0 Z-trim(122.6): 148 B-trim: 730 in 1/57
Lambda= 0.076092
statistics sampled from 40903 (41054) to 40903 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.481), width: 16
Scan time: 11.090
The best scores are: opt bits E(85289)
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 3167 360.7 4.8e-99
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 3167 360.7 4.8e-99
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 1249 150.1 1.2e-35
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 1232 148.2 4.1e-35
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 770 97.4 6.4e-20
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 616 80.7 1e-14
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 589 77.7 8.6e-14
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 550 73.2 1.1e-12
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 548 73.2 1.8e-12
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 527 70.8 7.2e-12
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 528 71.0 7.9e-12
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 512 69.2 2.4e-11
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 504 68.2 3.9e-11
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 499 67.7 6.6e-11
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 498 67.7 8.1e-11
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 487 66.4 1.5e-10
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 484 66.1 2.1e-10
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 484 66.1 2.1e-10
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 473 64.8 4e-10
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 475 65.1 4.3e-10
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 470 64.6 6e-10
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 453 62.7 2.1e-09
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 446 61.9 3.5e-09
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 444 61.7 4e-09
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 440 61.3 6.6e-09
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 403 57.3 1.3e-07
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 403 57.4 1.3e-07
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 403 57.4 1.3e-07
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 403 57.4 1.3e-07
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 403 57.4 1.3e-07
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 403 57.4 1.3e-07
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 402 57.2 1.3e-07
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 402 57.2 1.4e-07
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 402 57.2 1.4e-07
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 387 55.4 3.3e-07
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 377 54.5 9.9e-07
NP_658982 (OMIM: 274600,600791,601093) forkhead bo ( 283) 346 50.8 5.7e-06
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 349 51.4 7.5e-06
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 349 51.5 9e-06
NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365) 326 48.7 3.1e-05
XP_006712065 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 48.2 5.2e-05
XP_005264340 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 48.2 5.2e-05
XP_016859445 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 48.2 5.2e-05
XP_016859447 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 48.2 5.2e-05
NP_002149 (OMIM: 143089) forkhead box protein N2 [ ( 431) 321 48.2 5.2e-05
XP_016859448 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 48.2 5.2e-05
XP_006712064 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 48.2 5.2e-05
XP_011531110 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 48.2 5.2e-05
XP_016859446 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 48.2 5.2e-05
XP_005264339 (OMIM: 143089) PREDICTED: forkhead bo ( 431) 321 48.2 5.2e-05
>>NP_710141 (OMIM: 600288) hepatocyte nuclear factor 3-b (457 aa)
initn: 3167 init1: 3167 opt: 3167 Z-score: 1899.2 bits: 360.7 E(85289): 4.8e-99
Smith-Waterman score: 3167; 100.0% identity (100.0% similar) in 457 aa overlap (1-457:1-457)
10 20 30 40 50 60
pF1KB7 MLGAVKMEGHEPSDWSSYYAEPEGYSSVSNMNAGLGMNGMNTYMSMSAAAMGSGSGNMSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_710 MLGAVKMEGHEPSDWSSYYAEPEGYSSVSNMNAGLGMNGMNTYMSMSAAAMGSGSGNMSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLGGQAAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_710 GSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLGGQAAGA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 MGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_710 MGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKML
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 TLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_710 TLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 NMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGPASETPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_710 NMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGPASETPAG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 TESPHSSASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQQAAAHLLGPPHHPGLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_710 TESPHSSASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQQAAAHLLGPPHHPGLPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_710 EAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPG
370 380 390 400 410 420
430 440 450
pF1KB7 SLAMGPVTNKTGLDASPLAADTSYYQGVYSRPIMNSS
:::::::::::::::::::::::::::::::::::::
NP_710 SLAMGPVTNKTGLDASPLAADTSYYQGVYSRPIMNSS
430 440 450
>>NP_068556 (OMIM: 600288) hepatocyte nuclear factor 3-b (463 aa)
initn: 3167 init1: 3167 opt: 3167 Z-score: 1899.1 bits: 360.7 E(85289): 4.8e-99
Smith-Waterman score: 3167; 100.0% identity (100.0% similar) in 457 aa overlap (1-457:7-463)
10 20 30 40 50
pF1KB7 MLGAVKMEGHEPSDWSSYYAEPEGYSSVSNMNAGLGMNGMNTYMSMSAAAMGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MHSASSMLGAVKMEGHEPSDWSSYYAEPEGYSSVSNMNAGLGMNGMNTYMSMSAAAMGSG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 SGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 GQAAGAMGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYISLITMAIQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 GQAAGAMGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYISLITMAIQQ
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 SPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 LHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGPA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 SETPAGTESPHSSASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQQAAAHLLGPPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SETPAGTESPHSSASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQQAAAHLLGPPH
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 HPGLPPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 HPGLPPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGY
370 380 390 400 410 420
420 430 440 450
pF1KB7 GSPMPGSLAMGPVTNKTGLDASPLAADTSYYQGVYSRPIMNSS
:::::::::::::::::::::::::::::::::::::::::::
NP_068 GSPMPGSLAMGPVTNKTGLDASPLAADTSYYQGVYSRPIMNSS
430 440 450 460
>>NP_004487 (OMIM: 602294) hepatocyte nuclear factor 3-a (472 aa)
initn: 1245 init1: 802 opt: 1249 Z-score: 761.1 bits: 150.1 E(85289): 1.2e-35
Smith-Waterman score: 1597; 55.9% identity (73.9% similar) in 499 aa overlap (1-457:1-472)
10 20 30 40 50
pF1KB7 MLGAVKMEGHEPSDWSSYYAEP-EGYSSV--SNMNAGLG-MNGMNTYMSMSAAAMGSGSG
:::.::::::: :::.::::. :.:::: ::::.::: ::.:::::.:.. . ::
NP_004 MLGTVKMEGHETSDWNSYYADTQEAYSSVPVSNMNSGLGSMNSMNTYMTMNTM---TTSG
10 20 30 40 50
60 70 80 90 100
pF1KB7 NMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGM-GGSAGA------AGVAGMGPHLSPS
::. .:.::: :.. :.. ::.::: :.::: :::::: :::..:: ::::
NP_004 NMTPASFNMS-YANPGLG---AGLSPG--AVAGMPGGSAGAMNSMTAAGVTAMGTALSPS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB7 -LSPLGGQAAGAMGGLAPYAN-MNS-MSPM-YGQAGLSRAR-----DPKTYRRSYTHAKP
.. .:.: :..:.::.::: :: :::: :. ..:.:.: : ::..::: ::::
NP_004 GMGAMGAQQAASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKP
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 PYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKV
::::::::::::::.:.:::::::::::::::::.::::::::::::::::::::::.::
NP_004 PYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKV
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 PRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGA
::::::::::.:::::::::::::::::::::::::::: . ..:..::: ..: :.
NP_004 ARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPG-AGGGGGSGSGGSGAKGG
240 250 260 270 280 290
290 300 310 320
pF1KB7 QASQAQLGEAAGPASETP------------AGTESPHSSASP-CQEHK----RGGLGELK
:. . . :..:....: :. .: .::: .:. :: .:::
NP_004 PESRKDPSGASNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQTLDHSGATATGGASELK
300 310 320 330 340 350
330 340 350 360 370
pF1KB7 GTPAAALSPPEPAPSPGQQQQAAAHLLGPPHHP--GLPP---EAHLKPEHHYAFNHPFSI
:::.. .:: . .:: : : . : :: :: : . ::: . ::.:::::::
NP_004 -TPASSTAPP-ISSGPG----ALASV--PASHPAHGLAPHESQLHLKGDPHYSFNHPFSI
360 370 380 390 400
380 390 400 410 420 430
pF1KB7 NNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPGSLAMGPVTNKTGLDASPL
:::::: .:.: :.:.:::::...: ::: .:.:: .: .. : :
NP_004 NNLMSSSEQQH---------KLDFKAYEQALQYSPYGSTLPASLPLGSASVTTRSPIEPS
410 420 430 440 450
440 450
pF1KB7 AADTSYYQGVYSRPIMNSS
: . .:::::::::..:.:
NP_004 ALEPAYYQGVYSRPVLNTS
460 470
>>XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte nucl (439 aa)
initn: 1191 init1: 802 opt: 1232 Z-score: 751.4 bits: 148.2 E(85289): 4.1e-35
Smith-Waterman score: 1459; 54.7% identity (73.2% similar) in 466 aa overlap (31-457:1-439)
10 20 30 40 50
pF1KB7 MLGAVKMEGHEPSDWSSYYAEPEGYSSVSNMNAGLG-MNGMNTYMSMSAAAMGSGSGNMS
::.::: ::.:::::.:.. . ::::.
XP_016 MNSGLGSMNSMNTYMTMNTM---TTSGNMT
10 20
60 70 80 90 100 110
pF1KB7 AGSMNMSSYVGAGMSPSLAGMSPGAGAMAGM-GGSAGA------AGVAGMGPHLSPS-LS
.:.::: :.. :.. ::.:::: .::: :::::: :::..:: :::: ..
XP_016 PASFNMS-YANPGLG---AGLSPGA--VAGMPGGSAGAMNSMTAAGVTAMGTALSPSGMG
30 40 50 60 70 80
120 130 140 150 160
pF1KB7 PLGGQAAGAMGGLAPYAN-MNS-MSPM-YGQAGLSRAR-----DPKTYRRSYTHAKPPYS
.:.: :..:.::.::: :: :::: :. ..:.:.: : ::..::: :::::::
XP_016 AMGAQQAASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYS
90 100 110 120 130 140
170 180 190 200 210 220
pF1KB7 YISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRS
:::::::::::.:.:::::::::::::::::.::::::::::::::::::::::.:: ::
XP_016 YISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVARS
150 160 170 180 190 200
230 240 250 260 270 280
pF1KB7 PDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQAS
::::::::.:::::::::::::::::::::::::::: . ..:..::: ..: :. :
XP_016 PDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPG-AGGGGGSGSGGSGAKGGPES
210 220 230 240 250 260
290 300 310 320
pF1KB7 QAQLGEAAGPASETP------------AGTESPHSSASP-CQEHK----RGGLGELKGTP
. . . :..:....: :. .: .::: .:. :: .::: ::
XP_016 RKDPSGASNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQTLDHSGATATGGASELK-TP
270 280 290 300 310
330 340 350 360 370 380
pF1KB7 AAALSPPEPAPSPGQQQQAAAHLLGPPHHP--GLPP---EAHLKPEHHYAFNHPFSINNL
:.. .:: . .:: : : . : :: :: : . ::: . ::.::::::::::
XP_016 ASSTAPP-ISSGPG----ALASV--PASHPAHGLAPHESQLHLKGDPHYSFNHPFSINNL
320 330 340 350 360 370
390 400 410 420 430 440
pF1KB7 MSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPGSLAMGPVTNKTGLDASPLAAD
::: .:.: :.:.:::::...: ::: .:.:: .: .. : : : .
XP_016 MSSSEQQH---------KLDFKAYEQALQYSPYGSTLPASLPLGSASVTTRSPIEPSALE
380 390 400 410 420
450
pF1KB7 TSYYQGVYSRPIMNSS
.:::::::::..:.:
XP_016 PAYYQGVYSRPVLNTS
430
>>NP_004488 (OMIM: 602295) hepatocyte nuclear factor 3-g (350 aa)
initn: 997 init1: 720 opt: 770 Z-score: 478.6 bits: 97.4 E(85289): 6.4e-20
Smith-Waterman score: 934; 42.0% identity (59.5% similar) in 459 aa overlap (1-457:1-350)
10 20 30 40 50 60
pF1KB7 MLGAVKMEGHEPSDWSSYYAEPEGYSSVSNMNAGLGMNGMNTYMSMSAAAMGSGSGNMSA
:::.::::.:. ..:: : : :: :. . . : .:.::... . :.. :
NP_004 MLGSVKMEAHDLAEWSYYPEAGEVYSPVTPVPT---MAPLNSYMTLNPLSSPYPPGGLPA
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 GSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLGGQAAGA
. . :: . ..: : : : .:: . :.:. ::.....
NP_004 SPL-----------PS-GPLAPPAPA-------------APLGPTF-PGLGVSGGSSSSG
60 70 80 90
130 140 150 160 170
pF1KB7 MGGLAPYANMNSMSPMYGQAGLSRARD-PKTYRRSYTHAKPPYSYISLITMAIQQSPNKM
.:. .: :: .... :: ::: .::::::::::::::::::.:.::
NP_004 YGAPGP--------------GLVHGKEMPKGYRRPLAHAKPPYSYISLITMAIQQAPGKM
100 110 120 130
180 190 200 210 220 230
pF1KB7 LTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDS
:::::::::::::::.::.:::::::::::::::::::.:: ::::::::::.:.:::.:
NP_004 LTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSS
140 150 160 170 180 190
240 250 260 270 280 290
pF1KB7 GNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGPASETPA
::::::::::::::::: :... ::...:: :. .. : ... .. :::
NP_004 GNMFENGCYLRRQKRFKLEEKV------------KKGGSGA-ATTTRNGTGSAASTTTPA
200 210 220 230 240
300 310 320 330 340 350
pF1KB7 GT-ESPHSSASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQQAAAHLLGPPHHPGL
.: :: . : : . : : ..::. :: : :. ::
NP_004 ATVTSPPQPPPPAPEPEAQG-----GEDVGALDCGSPASST-------------PYFTGL
250 260 270 280
360 370 380 390 400 410
pF1KB7 PPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPM
..:: . : :::::::::::: :: : :.:. . :::
NP_004 ELPGELKLDAPYNFNHPFSINNLMS-EQTP-------APPKLDVG-------FGGYG---
290 300 310 320
420 430 440 450
pF1KB7 PGSLAMGPVTNKTGLDASPLAADTSYYQGVYSRPIMNSS
: : .. :. ::::.::: ..:.:
NP_004 ----AEG---GEPGV----------YYQGLYSRSLLNAS
330 340 350
>>NP_005242 (OMIM: 153400,602402) forkhead box protein C (501 aa)
initn: 684 init1: 524 opt: 616 Z-score: 385.2 bits: 80.7 E(85289): 1e-14
Smith-Waterman score: 628; 39.9% identity (62.8% similar) in 293 aa overlap (101-383:14-277)
80 90 100 110 120 130
pF1KB7 AGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLGGQAAGAMGGLAPYANM
:. :.:: . .:::..::.: ..
NP_005 MQARYSVSDPNALGVVPYLSEQNYY---RAAGSYGGMASPMGV
10 20 30 40
140 150 160 170 180
pF1KB7 NSMSPMYGQAGLSRARDPKTYRRSYTH---AKPPYSYISLITMAIQQSPNKMLTLSEIYQ
: : .::..:. : ... . .:::::::.:::::::..:.: .::. :::
NP_005 YSGHPEQYSAGMGRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQ
50 60 70 80 90 100
190 200 210 220 230 240
pF1KB7 WIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGC
.::: :::::.:.: :::::::.::.:.::.::::. ::::::.::: ::: ::::::
NP_005 FIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGS
110 120 130 140 150 160
250 260 270 280 290 300
pF1KB7 YLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQLGEAAGPASETPAGTESPHSS
.:::..::: :: .. . .:.: : : . . .. .:: .
NP_005 FLRRRRRFK-----------------KKDVSKEKEERAHLKEP--PPAASKGAPATPHLA
170 180 190 200
310 320 330 340 350 360
pF1KB7 ASPCQEHKRGGLGELKGTPAAALSPPEPAPSPGQQQQAAAHLLGPPHH----PGLPPEAH
.: . .:. . . : :: :. . . . . : : :. :. :..
NP_005 DAPKEAEKKVVI------KSEAASPALPVITKVETLSPESALQGSPRSAASTPAGSPDGS
210 220 230 240 250
370 380 390 400 410 420
pF1KB7 LKPEHHYAFNH--P-FSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPG
: :::: : . : ::..:.:.
NP_005 L-PEHHAAAPNGLPGFSVENIMTLRTSPPGGELSPGAGRAGLVVPPLALPYAAAPPAAYG
260 270 280 290 300 310
>>NP_001444 (OMIM: 601090,601631,602482) forkhead box pr (553 aa)
initn: 620 init1: 527 opt: 589 Z-score: 368.6 bits: 77.7 E(85289): 8.6e-14
Smith-Waterman score: 634; 36.6% identity (56.8% similar) in 380 aa overlap (93-443:6-370)
70 80 90 100 110 120
pF1KB7 MNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLGGQAAGAMG
:... . :. :.:. : . ::.: :
NP_001 MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGG
10 20 30
130 140 150 160 170
pF1KB7 GLAPY-ANMNSMS-PMYGQ---AGLSRARDPKTYR-RSYTHAKPPYSYISLITMAIQQSP
: . . : :. .: : ... .:..:: : : . . .:::::::.:::::::..:
NP_001 GYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAP
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB7 NKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLH
.: .::. :::.::: :::::.:.: :::::::.::.:.::.::::. ::::::.:::
NP_001 DKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLD
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB7 PDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQL----GEAAG
::: :::::: .:::..::: . . :: . : : : :.: :
NP_001 PDSYNMFENGSFLRRRRRFKKKDAVKDKEEKDRLHLKEPPPPGRQPPPAPPEQADGNAPG
160 170 180 190 200 210
300 310 320 330
pF1KB7 PAS--------ETPAGT-ESPHSSASPCQEHKRGGLG-----ELKGTPAAALS----PPE
: .: :: :: . :: :. . : . ...:: ::
NP_001 PQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPG
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB7 PAPSPGQQQQAAAHLLGPPHHPGLPPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHH
:: . .: :: :. :: :.: .. ::..:.:.: . .:
NP_001 SLPSARPLSLDGADSAPPPPAPSAPP-----PHH----SQGFSVDNIMTSLRGSPQSAAA
280 290 300 310 320
400 410 420 430 440 450
pF1KB7 HQPHKMDLKAYEQVMHYPGYGSPMPGSLAMGPVT-NKTGLDASPLAADTSYYQGVYSRPI
. . : : . : . : ::.: . ....: .:: . .:
NP_001 EL--SSGLLASAAASSRAGIAPP----LALGAYSPGQSSLYSSPCSQTSSAGSSGGGGGG
330 340 350 360 370 380
pF1KB7 MNSS
NP_001 AGAAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGAPGGAGGSAVDDPLPDYSLPPVTSSS
390 400 410 420 430 440
>>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa)
initn: 555 init1: 460 opt: 550 Z-score: 348.6 bits: 73.2 E(85289): 1.1e-12
Smith-Waterman score: 551; 37.7% identity (60.3% similar) in 292 aa overlap (87-364:1-287)
60 70 80 90 100 110
pF1KB7 NMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPLGGQ
::: . :. .:. : : :...: .:
NP_036 MAGRSDMDPPAAFSGF-PAL-PAVAP-SGP
10 20
120 130 140 150 160 170
pF1KB7 AAGAMGGLAPYANMNSMSPMYGQAGLSRARDP-KTYRRSYTHAKPPYSYISLITMAIQQS
. ..: : . . . :.:. . : : . :: ..:::::::.::.::. ..
NP_036 PPSPLAGAEPGREPEEAAAGRGEAAPTPAPGPGRRRRRPLQRGKPPYSYIALIAMALAHA
30 40 50 60 70 80
180 190 200 210 220 230
pF1KB7 PNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTL
:.. :::. ::..: . : :::.. ..:::::::.:..::::.:::: : .::::..:::
NP_036 PGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTL
90 100 110 120 130 140
240 250 260 270 280 290
pF1KB7 HPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQL---GEAAG
: ...::.:: .:::.:::: . : :: . : : : : .::
NP_036 DPAAADMFDNGSFLRRRKRFKRAELPAHAAAAPGPPLPFPYAPYAPAPGPALLVPPPSAG
150 160 170 180 190 200
300 310 320 330 340
pF1KB7 PASETPAGTESPHSSASPCQEHKRGGLGELK----GTP---AAALSPPEPAPSPGQQQQA
:. :: : : .. . . .::: . ..: :::. : : :: .:.
NP_036 PGPSPPARLFSVDSLVN--LQPELAGLGAPEPPCCAAPDAAAAAFPPCAAAASPPLYSQV
210 220 230 240 250 260
350 360 370 380 390 400
pF1KB7 AAHLLGPPHHPG---LPPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDL
.:. : .:: :: : :
NP_036 PDRLVLPATRPGPGPLPAEPLLALAGPAAALGPLSPGEAYLRQPGFASGLERYL
270 280 290 300 310
>>NP_036315 (OMIM: 607836,611539) forkhead box protein D (478 aa)
initn: 594 init1: 467 opt: 548 Z-score: 345.1 bits: 73.2 E(85289): 1.8e-12
Smith-Waterman score: 569; 41.2% identity (62.0% similar) in 279 aa overlap (84-358:86-341)
60 70 80 90 100 110
pF1KB7 GSGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHLSPSLSPL
::: :: ::..:: :. . . .
NP_036 DEADEVPPAAPHHGQPQPPHQQPLTLPKEAAGAGAGPGGDVGA-------PEADGCKGGV
60 70 80 90 100
120 130 140 150 160 170
pF1KB7 GGQAAGAMGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYISLITMAIQ
::. .:: :: .: :. .: . ::. .. ::. . .:::::::.::::::
NP_036 GGEEGGASGG-GPGAGSGSAG------GLAPSK-PKN-----SLVKPPYSYIALITMAIL
110 120 130 140 150
180 190 200 210 220 230
pF1KB7 QSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFW
:::.: :::: : ..: . ::.::.. :::::::.::.::::.:.:: : .::::..:
NP_036 QSPQKKLTLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYW
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB7 TLHPDSGNMFENGCYLRRQKRFKCEKQLALKE--AAGAAGSGKKAAAGAQASQAQLGEAA
:: :.: .::.:: .:::.:::: ..: :.: : . : . :.: .. . :.
NP_036 TLDPQSEDMFDNGSFLRRRKRFKRHQQEHLREQTALMMQSFGAYSLAAAAGAAGPYGRPY
220 230 240 250 260 270
300 310 320 330 340
pF1KB7 GPASETPAGTESPHSSASPCQEHKRGGLGELKGTPAAALSPPE-PA-PSPGQQQQAAAHL
: . ::. : : .:. . :.: . :: : :: ..:::
NP_036 GLHPAAAAGAYS-HPAAAAAAAAAAALQYPYALPPVAPVLPPAVPLLPSGELGRKAAA--
280 290 300 310 320 330
350 360 370 380 390 400
pF1KB7 LGPPHHPGLPPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVM
.: :::
NP_036 FGSQLGPGLQLQLNSLGAAAAAAGTAGAAGTTASLIKSEPSARPSFSIENIIGGGPAAPG
340 350 360 370 380 390
>>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa)
initn: 499 init1: 464 opt: 527 Z-score: 334.0 bits: 70.8 E(85289): 7.2e-12
Smith-Waterman score: 537; 40.8% identity (64.4% similar) in 233 aa overlap (138-360:33-263)
110 120 130 140 150 160
pF1KB7 PSLSPLGGQAAGAMGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYISL
:.: .:. . .: ..:::::::.:
NP_004 AESGPPPPQPEVLATVKEERGETAAGAGVPGEA-TGRGAGGRRRKRPLQRGKPPYSYIAL
10 20 30 40 50 60
170 180 190 200 210 220
pF1KB7 ITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKP
:.::: ..:.. :::. ::..: . :::::.: ..:::::::.:..::::::.:: .:
NP_004 IAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGRP
70 80 90 100 110 120
230 240 250 260 270 280
pF1KB7 GKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQASQAQL
:::..:.: :.. .:::.: .:::.:::: ...:. : ... :::.: :. : .
NP_004 GKGNYWALDPNAEDMFESGSFLRRRKRFK-RSDLSTYPAYMHDAAAAAAAAAAAAAAAAI
130 140 150 160 170 180
290 300 310 320 330
pF1KB7 GEAAGPASETP------AGTESPHSSASPCQEHKRGGLGELK--G-TPAAALSPPE-PAP
.: ::.. : :: : .: : . .. : . : .: ::: :::
NP_004 FPGAVPAARPPYPGAVYAGYAPPSLAAPPPVYYPAASPGPCRVFGLVPERPLSPELGPAP
190 200 210 220 230 240
340 350 360 370 380 390
pF1KB7 SPGQQQQAAAHLLGPPHHPGLPPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQP
: . : : .: : :
NP_004 SGPGGSCAFASAGAPATTTGYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAGSAIFAAA
250 260 270 280 290 300
457 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 04:09:40 2016 done: Fri Nov 4 04:09:42 2016
Total Scan time: 11.090 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]