Result of FASTA (omim) for
pF1KB7032
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7032, 424 aa
1>>>pF1KB7032 424 - 424 aa - 424 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2823+/-0.000494; mu= 17.4947+/- 0.031
mean_var=59.1823+/-12.102, 0's: 0 Z-trim(106.7): 74 B-trim: 0 in 0/52
Lambda= 0.166716
statistics sampled from 14679 (14757) to 14679 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.503), E-opt: 0.2 (0.173), width: 16
Scan time: 8.160
The best scores are: opt bits E(85289)
XP_005253415 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 2738 667.5 1.8e-191
XP_016874773 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 2738 667.5 1.8e-191
NP_004973 (OMIM: 600935) ATP-sensitive inward rect ( 424) 2738 667.5 1.8e-191
XP_016874772 (OMIM: 600935) PREDICTED: ATP-sensiti ( 424) 2738 667.5 1.8e-191
NP_000516 (OMIM: 125853,600937,601820,606176,61058 ( 390) 1278 316.3 8.6e-86
NP_001159762 (OMIM: 125853,600937,601820,606176,61 ( 303) 1273 315.1 1.6e-85
XP_006718289 (OMIM: 125853,600937,601820,606176,61 ( 303) 1273 315.1 1.6e-85
XP_016873169 (OMIM: 125853,600937,601820,606176,61 ( 303) 1273 315.1 1.6e-85
NP_002231 (OMIM: 600877,614098) G protein-activate ( 423) 1167 289.6 1e-77
NP_004974 (OMIM: 600932) G protein-activated inwar ( 393) 1142 283.6 6.1e-76
XP_016856736 (OMIM: 600932) PREDICTED: G protein-a ( 450) 1142 283.6 6.9e-76
XP_011541111 (OMIM: 600734,613485,613677) PREDICTE ( 419) 1139 282.9 1.1e-75
NP_000881 (OMIM: 600734,613485,613677) G protein-a ( 419) 1139 282.9 1.1e-75
XP_011541112 (OMIM: 600734,613485,613677) PREDICTE ( 419) 1139 282.9 1.1e-75
NP_002230 (OMIM: 601534) G protein-activated inwar ( 501) 1114 276.9 8e-74
XP_005256682 (OMIM: 602323) PREDICTED: ATP-sensiti ( 433) 1106 274.9 2.7e-73
NP_066292 (OMIM: 602323) ATP-sensitive inward rect ( 433) 1106 274.9 2.7e-73
XP_011522133 (OMIM: 602323) PREDICTED: ATP-sensiti ( 433) 1106 274.9 2.7e-73
NP_001181887 (OMIM: 613236,613239) inward rectifie ( 433) 1097 272.8 1.2e-72
XP_005276976 (OMIM: 613236,613239) PREDICTED: inwa ( 535) 1097 272.8 1.4e-72
NP_690607 (OMIM: 600504) inward rectifier potassiu ( 445) 1061 264.1 5e-70
NP_004972 (OMIM: 600504) inward rectifier potassiu ( 445) 1061 264.1 5e-70
NP_722451 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 978 244.1 4.3e-64
NP_722450 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 978 244.1 4.3e-64
NP_722448 (OMIM: 241200,600359) ATP-sensitive inwa ( 372) 978 244.1 4.3e-64
NP_722449 (OMIM: 241200,600359) ATP-sensitive inwa ( 389) 978 244.1 4.5e-64
NP_000211 (OMIM: 241200,600359) ATP-sensitive inwa ( 391) 978 244.1 4.5e-64
NP_001247438 (OMIM: 601534) G protein-activated in ( 308) 920 230.1 5.8e-60
NP_000882 (OMIM: 170390,600681,609622,613980) inwa ( 427) 882 221.1 4.4e-57
NP_002232 (OMIM: 274600,600791,602208,612780) ATP- ( 379) 828 208.1 3.2e-53
NP_037480 (OMIM: 603953) ATP-sensitive inward rect ( 436) 781 196.8 9.2e-50
NP_001263368 (OMIM: 602106) ATP-sensitive inward r ( 375) 774 195.1 2.6e-49
XP_011527862 (OMIM: 602106) PREDICTED: ATP-sensiti ( 375) 774 195.1 2.6e-49
NP_001263364 (OMIM: 602106) ATP-sensitive inward r ( 375) 774 195.1 2.6e-49
XP_016883833 (OMIM: 602106) PREDICTED: ATP-sensiti ( 375) 774 195.1 2.6e-49
NP_733933 (OMIM: 602106) ATP-sensitive inward rect ( 375) 774 195.1 2.6e-49
NP_001263365 (OMIM: 602106) ATP-sensitive inward r ( 375) 774 195.1 2.6e-49
NP_733932 (OMIM: 602106) ATP-sensitive inward rect ( 375) 774 195.1 2.6e-49
XP_016883832 (OMIM: 602106) PREDICTED: ATP-sensiti ( 375) 774 195.1 2.6e-49
XP_005261032 (OMIM: 602106) PREDICTED: ATP-sensiti ( 375) 774 195.1 2.6e-49
XP_006724065 (OMIM: 602106) PREDICTED: ATP-sensiti ( 375) 774 195.1 2.6e-49
XP_011527863 (OMIM: 602106) PREDICTED: ATP-sensiti ( 375) 774 195.1 2.6e-49
XP_016883834 (OMIM: 602106) PREDICTED: ATP-sensiti ( 375) 774 195.1 2.6e-49
NP_001263366 (OMIM: 602106) ATP-sensitive inward r ( 375) 774 195.1 2.6e-49
NP_002234 (OMIM: 602106) ATP-sensitive inward rect ( 375) 774 195.1 2.6e-49
NP_001263367 (OMIM: 602106) ATP-sensitive inward r ( 375) 774 195.1 2.6e-49
XP_016880102 (OMIM: 605722) PREDICTED: inward rect ( 418) 672 170.6 6.9e-42
NP_001278553 (OMIM: 605722) inward rectifier potas ( 418) 672 170.6 6.9e-42
NP_001278554 (OMIM: 605722) inward rectifier potas ( 418) 672 170.6 6.9e-42
XP_011523083 (OMIM: 605722) PREDICTED: inward rect ( 418) 672 170.6 6.9e-42
>>XP_005253415 (OMIM: 600935) PREDICTED: ATP-sensitive i (424 aa)
initn: 2738 init1: 2738 opt: 2738 Z-score: 3558.5 bits: 667.5 E(85289): 1.8e-191
Smith-Waterman score: 2738; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KB7 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 KPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEGNQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEGNQN
370 380 390 400 410 420
pF1KB7 TSES
::::
XP_005 TSES
>>XP_016874773 (OMIM: 600935) PREDICTED: ATP-sensitive i (424 aa)
initn: 2738 init1: 2738 opt: 2738 Z-score: 3558.5 bits: 667.5 E(85289): 1.8e-191
Smith-Waterman score: 2738; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KB7 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 KPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEGNQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEGNQN
370 380 390 400 410 420
pF1KB7 TSES
::::
XP_016 TSES
>>NP_004973 (OMIM: 600935) ATP-sensitive inward rectifie (424 aa)
initn: 2738 init1: 2738 opt: 2738 Z-score: 3558.5 bits: 667.5 E(85289): 1.8e-191
Smith-Waterman score: 2738; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KB7 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 KPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEGNQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEGNQN
370 380 390 400 410 420
pF1KB7 TSES
::::
NP_004 TSES
>>XP_016874772 (OMIM: 600935) PREDICTED: ATP-sensitive i (424 aa)
initn: 2738 init1: 2738 opt: 2738 Z-score: 3558.5 bits: 667.5 E(85289): 1.8e-191
Smith-Waterman score: 2738; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KB7 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 KPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEGNQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEGNQN
370 380 390 400 410 420
pF1KB7 TSES
::::
XP_016 TSES
>>NP_000516 (OMIM: 125853,600937,601820,606176,610582,61 (390 aa)
initn: 1719 init1: 892 opt: 1278 Z-score: 1661.2 bits: 316.3 E(85289): 8.6e-86
Smith-Waterman score: 1774; 71.2% identity (87.8% similar) in 385 aa overlap (1-384:1-372)
10 20 30 40 50 60
pF1KB7 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI
::.::.::::::::.:.: :. ::: : : .:::..:.: ::.::::::::::::::.
NP_000 MLSRKGIIPEEYVLTRLA-EDPAKPRYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDV
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC
::::::::: :::.::::::::::::::. :::.::::::. : : .. :
NP_000 FTTLVDLKWPHTLLIFTMSFLCSWLLFAMAWWLIAFAHGDL-APSEGTAEP--------C
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK
::...::.:::::::::::::::::::.:::::::: .::.::::::.:::.::::::::
NP_000 VTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB7 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV
::::::::::::::.:::::.:.:.::::.:::::::::::::....:::.:::.:::::
NP_000 TAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEV
180 190 200 210 220 230
250 260 270 280 290
pF1KB7 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLAN-QDLEVIVILEGV
::.::.:::..: . .:.::::::::: :::: :::::.. .:: . ::::.:::::::
NP_000 VPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILEGV
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 VETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELD
::::::::::::::.:.:: ::.::: ::.::.: :::::::::::::: .: :.::.::
NP_000 VETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQLD
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB7 EKPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEGNQ
: : :...: . : .. ::::.
NP_000 EDHS-LLEALTLA--SARGPLRKRSVPMAKAKPKFSISPDSLS
360 370 380 390
>>NP_001159762 (OMIM: 125853,600937,601820,606176,610582 (303 aa)
initn: 1342 init1: 892 opt: 1273 Z-score: 1656.5 bits: 315.1 E(85289): 1.6e-85
Smith-Waterman score: 1324; 69.4% identity (86.9% similar) in 297 aa overlap (89-384:1-285)
60 70 80 90 100 110
pF1KB7 DIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLEST
. :::.::::::. . : .
NP_001 MAWWLIAFAHGDL---APSEGTAEP-----
10 20
120 130 140 150 160 170
pF1KB7 VCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIF
:::...::.:::::::::::::::::::.:::::::: .::.::::::.:::.::::::
NP_001 -CVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIF
30 40 50 60 70 80
180 190 200 210 220 230
pF1KB7 MKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEG
::::::::::::::::.:::::.:.:.::::.:::::::::::::....:::.:::.:::
NP_001 MKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEG
90 100 110 120 130 140
240 250 260 270 280 290
pF1KB7 EVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLAN-QDLEVIVILE
::::.::.:::..: . .:.::::::::: :::: :::::.. .:: . ::::.:::::
NP_001 EVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILE
150 160 170 180 190 200
300 310 320 330 340 350
pF1KB7 GVVETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARE
::::::::::::::::.:.:: ::.::: ::.::.: :::::::::::::: .: :.::.
NP_001 GVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQ
210 220 230 240 250 260
360 370 380 390 400 410
pF1KB7 LDEKPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEG
::: :.: ..: . : .. ::::.
NP_001 LDEDHSLL-EAL--TLASARGPLRKRSVPMAKAKPKFSISPDSLS
270 280 290 300
>>XP_006718289 (OMIM: 125853,600937,601820,606176,610582 (303 aa)
initn: 1342 init1: 892 opt: 1273 Z-score: 1656.5 bits: 315.1 E(85289): 1.6e-85
Smith-Waterman score: 1324; 69.4% identity (86.9% similar) in 297 aa overlap (89-384:1-285)
60 70 80 90 100 110
pF1KB7 DIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLEST
. :::.::::::. . : .
XP_006 MAWWLIAFAHGDL---APSEGTAEP-----
10 20
120 130 140 150 160 170
pF1KB7 VCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIF
:::...::.:::::::::::::::::::.:::::::: .::.::::::.:::.::::::
XP_006 -CVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIF
30 40 50 60 70 80
180 190 200 210 220 230
pF1KB7 MKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEG
::::::::::::::::.:::::.:.:.::::.:::::::::::::....:::.:::.:::
XP_006 MKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEG
90 100 110 120 130 140
240 250 260 270 280 290
pF1KB7 EVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLAN-QDLEVIVILE
::::.::.:::..: . .:.::::::::: :::: :::::.. .:: . ::::.:::::
XP_006 EVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILE
150 160 170 180 190 200
300 310 320 330 340 350
pF1KB7 GVVETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARE
::::::::::::::::.:.:: ::.::: ::.::.: :::::::::::::: .: :.::.
XP_006 GVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQ
210 220 230 240 250 260
360 370 380 390 400 410
pF1KB7 LDEKPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEG
::: :.: ..: . : .. ::::.
XP_006 LDEDHSLL-EAL--TLASARGPLRKRSVPMAKAKPKFSISPDSLS
270 280 290 300
>>XP_016873169 (OMIM: 125853,600937,601820,606176,610582 (303 aa)
initn: 1342 init1: 892 opt: 1273 Z-score: 1656.5 bits: 315.1 E(85289): 1.6e-85
Smith-Waterman score: 1324; 69.4% identity (86.9% similar) in 297 aa overlap (89-384:1-285)
60 70 80 90 100 110
pF1KB7 DIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLEST
. :::.::::::. . : .
XP_016 MAWWLIAFAHGDL---APSEGTAEP-----
10 20
120 130 140 150 160 170
pF1KB7 VCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIF
:::...::.:::::::::::::::::::.:::::::: .::.::::::.:::.::::::
XP_016 -CVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIF
30 40 50 60 70 80
180 190 200 210 220 230
pF1KB7 MKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEG
::::::::::::::::.:::::.:.:.::::.:::::::::::::....:::.:::.:::
XP_016 MKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEG
90 100 110 120 130 140
240 250 260 270 280 290
pF1KB7 EVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLAN-QDLEVIVILE
::::.::.:::..: . .:.::::::::: :::: :::::.. .:: . ::::.:::::
XP_016 EVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPSDLHHHQDLEIIVILE
150 160 170 180 190 200
300 310 320 330 340 350
pF1KB7 GVVETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARE
::::::::::::::::.:.:: ::.::: ::.::.: :::::::::::::: .: :.::.
XP_016 GVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTVKVPTPLCTARQ
210 220 230 240 250 260
360 370 380 390 400 410
pF1KB7 LDEKPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEG
::: :.: ..: . : .. ::::.
XP_016 LDEDHSLL-EAL--TLASARGPLRKRSVPMAKAKPKFSISPDSLS
270 280 290 300
>>NP_002231 (OMIM: 600877,614098) G protein-activated in (423 aa)
initn: 1143 init1: 888 opt: 1167 Z-score: 1516.4 bits: 289.6 E(85289): 1e-77
Smith-Waterman score: 1167; 48.6% identity (77.6% similar) in 352 aa overlap (14-363:32-375)
10 20 30 40
pF1KB7 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKA--RFIAKSG
: . : ..: . ::: . :.. :.:
NP_002 AKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKDG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 ACNLAHKNIREQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDI
::. : :.:: :.: :::::::::::: .:.::.: . .::.:...:::.:. .::.
NP_002 KCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDM
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB7 YAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLIL
..: . : ::::. .:.::::::::...:::.: :..:..:: .: .:..
NP_002 -DHIEDPSW-------TPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLI
130 140 150 160 170
170 180 190 200 210 220
pF1KB7 QNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMII
:...: :.:: :.::.:.: .: ..:::::.:: ::::..:.::::.::::::::.: :.
NP_002 QSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIV
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 SASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDIS
::.: ...:. : ::: .:..: :: : .. .:::.:::: : :...::...::
NP_002 EASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEIS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 ATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSK
..: ...::..:::::.::.::.: :::.:::. :: ::.::. ..: :.: : :::..
NP_002 KAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNS
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB7 FGNTVKVAAPRCSARELDEKPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRN
: .: ....: ::.:: : :
NP_002 FHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLEEQTERNGD
360 370 380 390 400 410
>>NP_004974 (OMIM: 600932) G protein-activated inward re (393 aa)
initn: 1152 init1: 894 opt: 1142 Z-score: 1484.4 bits: 283.6 E(85289): 6.1e-76
Smith-Waterman score: 1147; 47.6% identity (78.0% similar) in 336 aa overlap (25-360:16-340)
10 20 30 40 50 60
pF1KB7 MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDI
:: : : :.. :.: ::. . :.:: :.: :.
NP_004 MAQENAAFSPGQEEPPRRRGR---QRYVEKDGRCNVQQGNVRETYRYLTDL
10 20 30 40
70 80 90 100 110 120
pF1KB7 FTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVC
:::::::.:: .:..:.... .::.:. .:::.:...::. ..: .. : :
NP_004 FTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDL-EHLEDTAW-------TPC
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 VTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMK
:.:. .:..:::::::...:::.: :..:..:: .:..:.:: :.: ..:: :.::.:.:
NP_004 VNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVK
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 TAQAHRRAETLIFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEV
.: ..:: ::.:: :::...:.:.::.::::::::.: :. ::.: ..... : :::
NP_004 ISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEF
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 VPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV
.:.:: :. : .. .:::.::.: : :: ::... : : .:.:..:::::.:
NP_004 IPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPFWEASRRALERDDFEIVVILEGMV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB7 ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDE
:.::.: :::.::...:. :::::.:..: :.: : :::..: .: .: .: :::::: :
NP_004 EATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEVDYASFHETFEVPTPSCSARELAE
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB7 KPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRRNNSSLMVPKVQFMTPEGNQN
NP_004 AAARLDAHLYWSIPSRLDEKVEEEGAGEGAGGEAGADKEQNGCLPPPESESKV
350 360 370 380 390
424 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 04:07:46 2016 done: Fri Nov 4 04:07:47 2016
Total Scan time: 8.160 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]