Result of FASTA (omim) for
pF1KB7018
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7018, 972 aa
1>>>pF1KB7018 972 - 972 aa - 972 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.5962+/-0.000675; mu= -24.1150+/- 0.041
mean_var=967.9557+/-224.389, 0's: 0 Z-trim(113.4): 674 B-trim: 0 in 0/60
Lambda= 0.041224
statistics sampled from 22115 (22776) to 22115 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.608), E-opt: 0.2 (0.267), width: 16
Scan time: 12.190
The best scores are: opt bits E(85289)
NP_001087241 (OMIM: 154800,164920,172800,273300,60 ( 972) 6533 406.6 3.2e-112
XP_005265799 (OMIM: 154800,164920,172800,273300,60 ( 973) 6521 405.9 5.3e-112
XP_016863669 (OMIM: 154800,164920,172800,273300,60 ( 971) 6516 405.6 6.5e-112
NP_000213 (OMIM: 154800,164920,172800,273300,60676 ( 976) 6515 405.5 6.8e-112
XP_016863668 (OMIM: 154800,164920,172800,273300,60 ( 972) 6504 404.9 1.1e-111
XP_005265797 (OMIM: 154800,164920,172800,273300,60 ( 977) 6503 404.8 1.1e-111
XP_016863667 (OMIM: 154800,164920,172800,273300,60 ( 975) 6498 404.5 1.4e-111
XP_005265798 (OMIM: 154800,164920,172800,273300,60 ( 976) 6486 403.8 2.3e-111
NP_005202 (OMIM: 164770,221820) macrophage colony- ( 972) 2267 152.9 7.7e-36
NP_001275634 (OMIM: 164770,221820) macrophage colo ( 972) 2267 152.9 7.7e-36
XP_016875975 (OMIM: 136351,613065) PREDICTED: rece ( 921) 1514 108.1 2.3e-22
XP_011533320 (OMIM: 136351,613065) PREDICTED: rece ( 818) 1512 107.9 2.3e-22
XP_016875976 (OMIM: 136351,613065) PREDICTED: rece ( 818) 1512 107.9 2.3e-22
XP_011533319 (OMIM: 136351,613065) PREDICTED: rece ( 818) 1512 107.9 2.3e-22
XP_016875978 (OMIM: 136351,613065) PREDICTED: rece ( 694) 1509 107.6 2.3e-22
XP_016875977 (OMIM: 136351,613065) PREDICTED: rece ( 700) 1509 107.6 2.3e-22
XP_011533317 (OMIM: 136351,613065) PREDICTED: rece ( 974) 1512 108.0 2.5e-22
NP_004110 (OMIM: 136351,613065) receptor-type tyro ( 993) 1512 108.0 2.6e-22
NP_002010 (OMIM: 165070) vascular endothelial grow (1338) 1081 82.5 1.6e-14
XP_016863771 (OMIM: 173490,606764,607685) PREDICTE ( 807) 1042 79.9 5.9e-14
XP_016863770 (OMIM: 173490,606764,607685) PREDICTE ( 820) 1042 79.9 5.9e-14
XP_006714104 (OMIM: 173490,606764,607685) PREDICTE ( 832) 1042 79.9 6e-14
XP_005265800 (OMIM: 173490,606764,607685) PREDICTE (1089) 822 67.0 6.1e-10
XP_011532687 (OMIM: 173490,606764,607685) PREDICTE (1089) 822 67.0 6.1e-10
NP_006197 (OMIM: 173490,606764,607685) platelet-de (1089) 822 67.0 6.1e-10
XP_016863769 (OMIM: 173490,606764,607685) PREDICTE (1102) 822 67.0 6.2e-10
XP_006714102 (OMIM: 173490,606764,607685) PREDICTE (1114) 822 67.0 6.2e-10
XP_005268521 (OMIM: 131440,173410,213600,228550,60 (1042) 759 63.2 8e-09
XP_011535960 (OMIM: 131440,173410,213600,228550,60 (1106) 759 63.3 8.3e-09
NP_002600 (OMIM: 131440,173410,213600,228550,60181 (1106) 759 63.3 8.3e-09
XP_011535961 (OMIM: 131440,173410,213600,228550,60 (1106) 759 63.3 8.3e-09
NP_002244 (OMIM: 191306,602089) vascular endotheli (1356) 747 62.7 1.5e-08
XP_011532786 (OMIM: 136352,153100,602089) PREDICTE (1210) 721 61.1 4.2e-08
NP_002011 (OMIM: 136352,153100,602089) vascular en (1298) 721 61.1 4.4e-08
XP_016864757 (OMIM: 136352,153100,602089) PREDICTE (1337) 721 61.1 4.4e-08
NP_891555 (OMIM: 136352,153100,602089) vascular en (1363) 721 61.1 4.5e-08
XP_016864755 (OMIM: 136352,153100,602089) PREDICTE (1375) 721 61.1 4.5e-08
XP_016864756 (OMIM: 136352,153100,602089) PREDICTE (1375) 721 61.1 4.5e-08
XP_016864754 (OMIM: 136352,153100,602089) PREDICTE (1385) 721 61.1 4.5e-08
XP_016864753 (OMIM: 136352,153100,602089) PREDICTE (1385) 721 61.1 4.5e-08
XP_016864752 (OMIM: 136352,153100,602089) PREDICTE (1385) 721 61.1 4.5e-08
XP_011532780 (OMIM: 136352,153100,602089) PREDICTE (1440) 721 61.2 4.6e-08
XP_016875974 (OMIM: 165070) PREDICTED: vascular en (1300) 709 60.4 7.2e-08
NP_001307583 (OMIM: 101200,101400,101600,123150,12 ( 593) 695 59.1 8e-08
XP_016868719 (OMIM: 101600,123150,136350,147950,16 ( 498) 690 58.7 8.8e-08
NP_001138390 (OMIM: 101200,101400,101600,123150,12 ( 704) 695 59.2 8.8e-08
NP_001138389 (OMIM: 101200,101400,101600,123150,12 ( 705) 695 59.2 8.8e-08
NP_001138388 (OMIM: 101200,101400,101600,123150,12 ( 706) 695 59.2 8.8e-08
NP_001138386 (OMIM: 101200,101400,101600,123150,12 ( 709) 695 59.2 8.9e-08
XP_016871413 (OMIM: 101200,101400,101600,123150,12 ( 725) 695 59.2 9e-08
>>NP_001087241 (OMIM: 154800,164920,172800,273300,606764 (972 aa)
initn: 6533 init1: 6533 opt: 6533 Z-score: 2135.6 bits: 406.6 E(85289): 3.2e-112
Smith-Waterman score: 6533; 100.0% identity (100.0% similar) in 972 aa overlap (1-972:1-972)
10 20 30 40 50 60
pF1KB7 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSAN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 VTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 DYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 LVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 SAFKHNGTVECKAYNDVGKTSAYFNFAFKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAFKHNGTVECKAYNDVGKTSAYFNFAFKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 YKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 EATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 PTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMDM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB7 KPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB7 SKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNC
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB7 VYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMK
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB7 TCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGSTA
910 920 930 940 950 960
970
pF1KB7 SSSQPLLVHDDV
::::::::::::
NP_001 SSSQPLLVHDDV
970
>>XP_005265799 (OMIM: 154800,164920,172800,273300,606764 (973 aa)
initn: 4847 init1: 4847 opt: 6521 Z-score: 2131.7 bits: 405.9 E(85289): 5.3e-112
Smith-Waterman score: 6521; 99.9% identity (99.9% similar) in 973 aa overlap (1-972:1-973)
10 20 30 40 50 60
pF1KB7 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
190 200 210 220 230 240
250 260 270 280 290
pF1KB7 SVYSTWKRENSQ-TKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSA
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVYSTWKRENSQQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 NVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKW
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 EDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYD
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB7 RLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSID
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB7 SSAFKHNGTVECKAYNDVGKTSAYFNFAFKEQIHPHTLFTPLLIGFVIVAGMMCIIVMIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSAFKHNGTVECKAYNDVGKTSAYFNFAFKEQIHPHTLFTPLLIGFVIVAGMMCIIVMIL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB7 TYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKV
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB7 VEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIG
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB7 GPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMD
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB7 MKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFL
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB7 ASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFN
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB7 CVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIM
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB7 KTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGST
910 920 930 940 950 960
960 970
pF1KB7 ASSSQPLLVHDDV
:::::::::::::
XP_005 ASSSQPLLVHDDV
970
>>XP_016863669 (OMIM: 154800,164920,172800,273300,606764 (971 aa)
initn: 4772 init1: 4772 opt: 6516 Z-score: 2130.1 bits: 405.6 E(85289): 6.5e-112
Smith-Waterman score: 6516; 99.9% identity (99.9% similar) in 972 aa overlap (1-972:1-971)
10 20 30 40 50 60
pF1KB7 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSAN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 VTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 DYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 LVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 SAFKHNGTVECKAYNDVGKTSAYFNFAFKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAFKHNGTVECKAYNDVGKTSAYFNFAFKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB7 YKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB7 EATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB7 PTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMDM
:::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
XP_016 PTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSC-DSTNEYMDM
670 680 690 700 710
730 740 750 760 770 780
pF1KB7 KPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLA
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB7 SKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNC
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB7 VYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMK
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB7 TCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGSTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGSTA
900 910 920 930 940 950
970
pF1KB7 SSSQPLLVHDDV
::::::::::::
XP_016 SSSQPLLVHDDV
960 970
>>NP_000213 (OMIM: 154800,164920,172800,273300,606764) m (976 aa)
initn: 3428 init1: 3428 opt: 6515 Z-score: 2129.8 bits: 405.5 E(85289): 6.8e-112
Smith-Waterman score: 6515; 99.6% identity (99.6% similar) in 976 aa overlap (1-972:1-976)
10 20 30 40 50 60
pF1KB7 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSAN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 VTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 DYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 LVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDS
430 440 450 460 470 480
490 500 510 520 530
pF1KB7 SAFKHNGTVECKAYNDVGKTSAYFNFAFK----EQIHPHTLFTPLLIGFVIVAGMMCIIV
::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_000 SAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB7 MILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAF
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB7 GKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGAC
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB7 TIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB7 YMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGM
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB7 AFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPES
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB7 IFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMY
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB7 DIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSV
910 920 930 940 950 960
960 970
pF1KB7 GSTASSSQPLLVHDDV
::::::::::::::::
NP_000 GSTASSSQPLLVHDDV
970
>>XP_016863668 (OMIM: 154800,164920,172800,273300,606764 (972 aa)
initn: 3086 init1: 3086 opt: 6504 Z-score: 2126.3 bits: 404.9 E(85289): 1.1e-111
Smith-Waterman score: 6504; 99.8% identity (99.8% similar) in 973 aa overlap (1-972:1-972)
10 20 30 40 50 60
pF1KB7 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
190 200 210 220 230 240
250 260 270 280 290
pF1KB7 SVYSTWKRENSQ-TKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSA
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVYSTWKRENSQQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 NVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKW
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 EDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYD
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB7 RLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSID
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB7 SSAFKHNGTVECKAYNDVGKTSAYFNFAFKEQIHPHTLFTPLLIGFVIVAGMMCIIVMIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSAFKHNGTVECKAYNDVGKTSAYFNFAFKEQIHPHTLFTPLLIGFVIVAGMMCIIVMIL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB7 TYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKV
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB7 VEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIG
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB7 GPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMD
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
XP_016 GPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSC-DSTNEYMD
670 680 690 700 710
720 730 740 750 760 770
pF1KB7 MKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFL
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB7 ASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFN
780 790 800 810 820 830
840 850 860 870 880 890
pF1KB7 CVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIM
840 850 860 870 880 890
900 910 920 930 940 950
pF1KB7 KTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGST
900 910 920 930 940 950
960 970
pF1KB7 ASSSQPLLVHDDV
:::::::::::::
XP_016 ASSSQPLLVHDDV
960 970
>>XP_005265797 (OMIM: 154800,164920,172800,273300,606764 (977 aa)
initn: 4795 init1: 3111 opt: 6503 Z-score: 2125.9 bits: 404.8 E(85289): 1.1e-111
Smith-Waterman score: 6503; 99.5% identity (99.5% similar) in 977 aa overlap (1-972:1-977)
10 20 30 40 50 60
pF1KB7 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
190 200 210 220 230 240
250 260 270 280 290
pF1KB7 SVYSTWKRENSQ-TKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSA
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVYSTWKRENSQQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 NVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKW
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 EDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYD
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB7 RLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSID
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB7 SSAFKHNGTVECKAYNDVGKTSAYFNFAFK----EQIHPHTLFTPLLIGFVIVAGMMCII
:::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_005 SSAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCII
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB7 VMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGA
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB7 FGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGA
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB7 CTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTN
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB7 EYMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EYMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKG
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB7 MAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB7 SIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEM
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB7 YDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINS
910 920 930 940 950 960
960 970
pF1KB7 VGSTASSSQPLLVHDDV
:::::::::::::::::
XP_005 VGSTASSSQPLLVHDDV
970
>>XP_016863667 (OMIM: 154800,164920,172800,273300,606764 (975 aa)
initn: 5176 init1: 3428 opt: 6498 Z-score: 2124.3 bits: 404.5 E(85289): 1.4e-111
Smith-Waterman score: 6498; 99.5% identity (99.5% similar) in 976 aa overlap (1-972:1-975)
10 20 30 40 50 60
pF1KB7 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSAN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 VTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 DYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 LVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDS
430 440 450 460 470 480
490 500 510 520 530
pF1KB7 SAFKHNGTVECKAYNDVGKTSAYFNFAFK----EQIHPHTLFTPLLIGFVIVAGMMCIIV
::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_016 SAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB7 MILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAF
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB7 GKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGAC
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB7 TIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNE
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
XP_016 TIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSC-DSTNE
670 680 690 700 710
720 730 740 750 760 770
pF1KB7 YMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGM
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB7 AFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPES
780 790 800 810 820 830
840 850 860 870 880 890
pF1KB7 IFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMY
840 850 860 870 880 890
900 910 920 930 940 950
pF1KB7 DIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSV
900 910 920 930 940 950
960 970
pF1KB7 GSTASSSQPLLVHDDV
::::::::::::::::
XP_016 GSTASSSQPLLVHDDV
960 970
>>XP_005265798 (OMIM: 154800,164920,172800,273300,606764 (976 aa)
initn: 3490 init1: 1762 opt: 6486 Z-score: 2120.5 bits: 403.8 E(85289): 2.3e-111
Smith-Waterman score: 6486; 99.4% identity (99.4% similar) in 977 aa overlap (1-972:1-976)
10 20 30 40 50 60
pF1KB7 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSS
190 200 210 220 230 240
250 260 270 280 290
pF1KB7 SVYSTWKRENSQ-TKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSA
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVYSTWKRENSQQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB7 NVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKW
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB7 EDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYD
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB7 RLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSID
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB7 SSAFKHNGTVECKAYNDVGKTSAYFNFAFK----EQIHPHTLFTPLLIGFVIVAGMMCII
:::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
XP_005 SSAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCII
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB7 VMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGA
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB7 FGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGA
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB7 CTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_005 CTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSC-DSTN
670 680 690 700 710
720 730 740 750 760 770
pF1KB7 EYMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EYMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKG
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB7 MAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPE
780 790 800 810 820 830
840 850 860 870 880 890
pF1KB7 SIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEM
840 850 860 870 880 890
900 910 920 930 940 950
pF1KB7 YDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINS
900 910 920 930 940 950
960 970
pF1KB7 VGSTASSSQPLLVHDDV
:::::::::::::::::
XP_005 VGSTASSSQPLLVHDDV
960 970
>>NP_005202 (OMIM: 164770,221820) macrophage colony-stim (972 aa)
initn: 1838 init1: 822 opt: 2267 Z-score: 764.4 bits: 152.9 E(85289): 7.7e-36
Smith-Waterman score: 2301; 42.1% identity (69.5% similar) in 932 aa overlap (37-939:21-930)
10 20 30 40 50 60
pF1KB7 AWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTDPGFVKW
: :.:. .:.:. : . : :. : :.:
NP_005 MGPGVLLLLLVATAWHGQGIPVIEPSVPELVVKPGATVTLRCVGNGSVEW
10 20 30 40 50
70 80 90 100 110
pF1KB7 TFEILDE---TNENKQNEWITEKAEATNTGKYTCT---NKHGLSNSIYVFVRDPAKLF-L
. ...... :..: ::: : :: . : : .:...:.:::. . .
NP_005 DGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 VDRSLYGKEDNDTLVRCPLTDPEV-TNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRA
. . . ::.:.:. : :::: . .. :: .:.:: . . .: :. :. .:
NP_005 LAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 YHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDV
. .::. . :..:.: .. :::. .. . :.... : . .:: ..:. ..:
NP_005 QSQD-YQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSV
180 190 200 210 220
240 250 260 270 280 290
pF1KB7 SSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGS
. . .... ..:. ::: .: :.. :.. ::..... . .: . : :.:. :.
NP_005 DVN-FDVFLQHNN-TKLAIPQQSDFHNN-RYQKVLTLNLDQVDFQHAGNYSCVASNVQGK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB7 ANVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDK
... ..::.....:. : :. ::...: : ::.: . .: :.. :.:.
NP_005 HSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNLKVMVEAYPGLQGFNWTYLG-PFSDH
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB7 WEDYPKSENESN---IRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI
. :: : .. :.. : : ::: .:.: :.::. : :..:.. . ::.
NP_005 QPE-PKLANATTKDTYRHTFTLSLPRLKPSEAGRYSFLARNPGGWRALTFELTLRYPPEV
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB7 LTYDRLVNG--MLQCVAAGFPEPTIDWYFCPGTEQRCS-ASVLPV--DVQTLNSSGPPFG
. ..:: : :.:.:.:.:.. : : : .::. :.:: : : : ::
NP_005 SVIWTFINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFH
410 420 430 440 450 460
480 490 500 510 520
pF1KB7 KLVVQSSIDSSAFKHNGTVECKAYNDVGKTS-AYFNFAFKEQIHP--HTLFTPLLIGFVI
:..::: . ...:: : ::.:.:.::. : :.. .. . :: . ::::.... .
NP_005 KVTVQSLLTVETLEHNQTYECRAHNSVGSGSWAFIPISAGAHTHPPDEFLFTPVVVACMS
470 480 490 500 510 520
530 540 550 560 570 580
pF1KB7 VAGMMCIIVMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSF
. ... .....: ::: ::: :.:.::..: .::.:..::::::::..::::::: :.:
NP_005 IMALLLLLLLLLLYKYKQKPKYQVRWKIIESYEGNSYTFIDPTQLPYNEKWEFPRNNLQF
530 540 550 560 570 580
590 600 610 620 630 640
pF1KB7 GKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHM
:::::::::::::::::.:: : ::.. ::::::: .:: :.::::::::..:.::.:
NP_005 GKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHE
590 600 610 620 630 640
650 660 670 680 690 700
pF1KB7 NIVNLLGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFI---CSKQEDHAEAALYKNLLH
:::::::::: :::.::::::::::::::::::: .... : .: .. :::.
NP_005 NIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKAEAMLGPSLSPGQDPEGGVDYKNIHL
650 660 670 680 690 700
710 720 730 740 750
pF1KB7 SKESSCSDS------TNEYMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDEL
:. :: .. :..:.: : :... :. :.:. ..:
NP_005 EKKYVRRDSGFSSQGVDTYVEMRP-----VSTSSND-------SFSEQDLD----KEDGR
710 720 730 740
760 770 780 790 800 810
pF1KB7 ALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSN
:.:.::: :: :::.::::::::::::::.::::.:::.:...:: :::::::: ::::
NP_005 PLELRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSN
750 760 770 780 790 800
820 830 840 850 860 870
pF1KB7 YVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKM
:.::::::::::::::::::.:::: .::::::::.:::.:::: .::::. :.:::::.
NP_005 YIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKL
810 820 830 840 850 860
880 890 900 910 920 930
pF1KB7 IKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISEST-NHIYSNLAN
.:.:..: .: :: ..:.::..:: .: .::::.:: .....: .:. .. :.:: .
NP_005 VKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQICSFLQEQAQEDRRERDYTNLPS
870 880 890 900 910 920
940 950 960 970
pF1KB7 CSPNRQKPVVDHSVRINSVGSTASSSQPLLVHDDV
:
NP_005 SSRSGGSGSSSSELEEESSSEHLTCCEQGDIAQPLLQPNNYQFC
930 940 950 960 970
>>NP_001275634 (OMIM: 164770,221820) macrophage colony-s (972 aa)
initn: 1838 init1: 822 opt: 2267 Z-score: 764.4 bits: 152.9 E(85289): 7.7e-36
Smith-Waterman score: 2301; 42.1% identity (69.5% similar) in 932 aa overlap (37-939:21-930)
10 20 30 40 50 60
pF1KB7 AWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTDPGFVKW
: :.:. .:.:. : . : :. : :.:
NP_001 MGPGVLLLLLVATAWHGQGIPVIEPSVPELVVKPGATVTLRCVGNGSVEW
10 20 30 40 50
70 80 90 100 110
pF1KB7 TFEILDE---TNENKQNEWITEKAEATNTGKYTCT---NKHGLSNSIYVFVRDPAKLF-L
. ...... :..: ::: : :: . : : .:...:.:::. . .
NP_001 DGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 VDRSLYGKEDNDTLVRCPLTDPEV-TNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRA
. . . ::.:.:. : :::: . .. :: .:.:: . . .: :. :. .:
NP_001 LAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKFI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 YHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDV
. .::. . :..:.: .. :::. .. . :.... : . .:: ..:. ..:
NP_001 QSQD-YQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEAAQIVCSASSV
180 190 200 210 220
240 250 260 270 280 290
pF1KB7 SSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGS
. . .... ..:. ::: .: :.. :.. ::..... . .: . : :.:. :.
NP_001 DVN-FDVFLQHNN-TKLAIPQQSDFHNN-RYQKVLTLNLDQVDFQHAGNYSCVASNVQGK
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB7 ANVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDK
... ..::.....:. : :. ::...: : ::.: . .: :.. :.:.
NP_001 HSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNLKVMVEAYPGLQGFNWTYLG-PFSDH
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB7 WEDYPKSENESN---IRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEI
. :: : .. :.. : : ::: .:.: :.::. : :..:.. . ::.
NP_001 QPE-PKLANATTKDTYRHTFTLSLPRLKPSEAGRYSFLARNPGGWRALTFELTLRYPPEV
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB7 LTYDRLVNG--MLQCVAAGFPEPTIDWYFCPGTEQRCS-ASVLPV--DVQTLNSSGPPFG
. ..:: : :.:.:.:.:.. : : : .::. :.:: : : : ::
NP_001 SVIWTFINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFH
410 420 430 440 450 460
480 490 500 510 520
pF1KB7 KLVVQSSIDSSAFKHNGTVECKAYNDVGKTS-AYFNFAFKEQIHP--HTLFTPLLIGFVI
:..::: . ...:: : ::.:.:.::. : :.. .. . :: . ::::.... .
NP_001 KVTVQSLLTVETLEHNQTYECRAHNSVGSGSWAFIPISAGAHTHPPDEFLFTPVVVACMS
470 480 490 500 510 520
530 540 550 560 570 580
pF1KB7 VAGMMCIIVMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSF
. ... .....: ::: ::: :.:.::..: .::.:..::::::::..::::::: :.:
NP_001 IMALLLLLLLLLLYKYKQKPKYQVRWKIIESYEGNSYTFIDPTQLPYNEKWEFPRNNLQF
530 540 550 560 570 580
590 600 610 620 630 640
pF1KB7 GKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHM
:::::::::::::::::.:: : ::.. ::::::: .:: :.::::::::..:.::.:
NP_001 GKTLGAGAFGKVVEATAFGLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHE
590 600 610 620 630 640
650 660 670 680 690 700
pF1KB7 NIVNLLGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFI---CSKQEDHAEAALYKNLLH
:::::::::: :::.::::::::::::::::::: .... : .: .. :::.
NP_001 NIVNLLGACTHGGPVLVITEYCCYGDLLNFLRRKAEAMLGPSLSPGQDPEGGVDYKNIHL
650 660 670 680 690 700
710 720 730 740 750
pF1KB7 SKESSCSDS------TNEYMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDEL
:. :: .. :..:.: : :... :. :.:. ..:
NP_001 EKKYVRRDSGFSSQGVDTYVEMRP-----VSTSSND-------SFSEQDLD----KEDGR
710 720 730 740
760 770 780 790 800 810
pF1KB7 ALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSN
:.:.::: :: :::.::::::::::::::.::::.:::.:...:: :::::::: ::::
NP_001 PLELRDLLHFSSQVAQGMAFLASKNCIHRDVAARNVLLTNGHVAKIGDFGLARDIMNDSN
750 760 770 780 790 800
820 830 840 850 860 870
pF1KB7 YVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKM
:.::::::::::::::::::.:::: .::::::::.:::.:::: .::::. :.:::::.
NP_001 YIVKGNARLPVKWMAPESIFDCVYTVQSDVWSYGILLWEIFSLGLNPYPGILVNSKFYKL
810 820 830 840 850 860
880 890 900 910 920 930
pF1KB7 IKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISEST-NHIYSNLAN
.:.:..: .: :: ..:.::..:: .: .::::.:: .....: .:. .. :.:: .
NP_001 VKDGYQMAQPAFAPKNIYSIMQACWALEPTHRPTFQQICSFLQEQAQEDRRERDYTNLPS
870 880 890 900 910 920
940 950 960 970
pF1KB7 CSPNRQKPVVDHSVRINSVGSTASSSQPLLVHDDV
:
NP_001 SSRSGGSGSSSSELEEESSSEHLTCCEQGDIAQPLLQPNNYQFC
930 940 950 960 970
972 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 22:52:52 2016 done: Thu Nov 3 22:52:54 2016
Total Scan time: 12.190 Total Display time: 0.360
Function used was FASTA [36.3.4 Apr, 2011]