Result of FASTA (omim) for
pF1KB6998
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6998, 217 aa
1>>>pF1KB6998 217 - 217 aa - 217 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4939+/-0.000366; mu= 12.6670+/- 0.023
mean_var=64.5694+/-12.817, 0's: 0 Z-trim(113.6): 45 B-trim: 0 in 0/52
Lambda= 0.159610
statistics sampled from 23047 (23080) to 23047 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.271), width: 16
Scan time: 6.110
The best scores are: opt bits E(85289)
NP_001308 (OMIM: 150200) chorionic somatomammotrop ( 217) 1448 341.9 4.6e-94
NP_066271 (OMIM: 118820) chorionic somatomammotrop ( 217) 1437 339.4 2.7e-93
NP_072101 (OMIM: 603515) chorionic somatomammotrop ( 222) 1284 304.2 1.1e-82
NP_000506 (OMIM: 139250,173100,262400,262650,61278 ( 217) 1228 291.3 8.3e-79
NP_002050 (OMIM: 139240) growth hormone variant is ( 217) 1129 268.5 6e-72
NP_072170 (OMIM: 118820) chorionic somatomammotrop ( 167) 996 237.8 7.9e-63
NP_001307998 (OMIM: 603515) chorionic somatomammot ( 183) 965 230.7 1.2e-60
NP_001307996 (OMIM: 603515) chorionic somatomammot ( 162) 957 228.8 3.9e-60
XP_011522646 (OMIM: 603515) PREDICTED: chorionic s ( 261) 872 209.3 4.6e-54
NP_072053 (OMIM: 139250,173100,262400,262650,61278 ( 202) 837 201.2 9.8e-52
NP_072103 (OMIM: 603515) chorionic somatomammotrop ( 199) 828 199.2 4.1e-51
NP_072102 (OMIM: 603515) chorionic somatomammotrop ( 139) 819 197.0 1.3e-50
NP_001307997 (OMIM: 603515) chorionic somatomammot ( 160) 819 197.1 1.4e-50
NP_072050 (OMIM: 139240) growth hormone variant is ( 202) 782 188.6 6.4e-48
NP_001309 (OMIM: 603515) chorionic somatomammotrop ( 128) 774 186.7 1.5e-47
NP_072052 (OMIM: 139240) growth hormone variant is ( 245) 735 177.8 1.4e-44
NP_072051 (OMIM: 139240) growth hormone variant is ( 256) 732 177.1 2.3e-44
NP_072054 (OMIM: 139250,173100,262400,262650,61278 ( 177) 714 172.9 2.9e-43
XP_011522648 (OMIM: 603515) PREDICTED: chorionic s ( 201) 545 134.0 1.7e-31
NP_072171 (OMIM: 118820) chorionic somatomammotrop ( 122) 446 111.1 8e-25
NP_000939 (OMIM: 176760) prolactin precursor [Homo ( 227) 249 65.9 6.3e-11
NP_001157030 (OMIM: 176760) prolactin precursor [H ( 227) 249 65.9 6.3e-11
XP_011513055 (OMIM: 176760) PREDICTED: prolactin i ( 228) 249 65.9 6.3e-11
XP_011513056 (OMIM: 176760) PREDICTED: prolactin i ( 228) 249 65.9 6.3e-11
>>NP_001308 (OMIM: 150200) chorionic somatomammotropin h (217 aa)
initn: 1448 init1: 1448 opt: 1448 Z-score: 1809.6 bits: 341.9 E(85289): 4.6e-94
Smith-Waterman score: 1448; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KB6 MAPGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHD
130 140 150 160 170 180
190 200 210
pF1KB6 ALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF
:::::::::::::::::::::::::::::::::::::
NP_001 ALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF
190 200 210
>>NP_066271 (OMIM: 118820) chorionic somatomammotropin h (217 aa)
initn: 1437 init1: 1437 opt: 1437 Z-score: 1796.0 bits: 339.4 E(85289): 2.7e-93
Smith-Waterman score: 1437; 99.5% identity (99.5% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KB6 MAPGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEET
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 YIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHD
130 140 150 160 170 180
190 200 210
pF1KB6 ALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF
:::::::::::::::::::::::::::::::::::::
NP_066 ALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF
190 200 210
>>NP_072101 (OMIM: 603515) chorionic somatomammotropin h (222 aa)
initn: 1292 init1: 957 opt: 1284 Z-score: 1605.4 bits: 304.2 E(85289): 1.1e-82
Smith-Waterman score: 1284; 90.1% identity (93.2% similar) in 222 aa overlap (1-217:1-222)
10 20 30 40 50
pF1KB6 MAPGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEF---
:: ::::::::::::::::::::::::::::::::: .:::::::::::::::::::
NP_072 MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFKEAMLQAHRAHQLAIDTYQEFISS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 --EETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEP
:.:: :.::::::::::::::::::::: :::::::::::::::.:::::::: :::
NP_072 WGMEAYITKEQKYSFLHDSQTSFCFSDSIPTSSNMEETQQKSNLELLHISLLLIESRLEP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 VRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTN
:::::: :.:::::::::::::::::::::::: :::::::::. ::: :::::::::::
NP_072 VRFLRSTFTNNLVYDTSDSDDYHLLKDLEEGIQMLMGRLEDGSHLTGQTLKQTYSKFDTN
130 140 150 160 170 180
180 190 200 210
pF1KB6 SHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF
::::::::::::::.:::::::::::::::::::::::::::
NP_072 SHNHDALLKNYGLLHCFRKDMDKVETFLRMVQCRSVEGSCGF
190 200 210 220
>>NP_000506 (OMIM: 139250,173100,262400,262650,612781) s (217 aa)
initn: 1228 init1: 1228 opt: 1228 Z-score: 1535.9 bits: 291.3 E(85289): 8.3e-79
Smith-Waterman score: 1228; 85.3% identity (94.9% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KB6 MAPGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEET
:: ::::::::::.:::::::::..: :.:::::::.:::.::: ::::.::::::::.
NP_000 MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLR
::::.::::::.. :::.:::.::::::: :::::::::::::::::::.::::::.:::
NP_000 YIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHD
:.:::.::: .:::. : :::::::::::::::::::: :::::.::::::::::::: :
NP_000 SVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDD
130 140 150 160 170 180
190 200 210
pF1KB6 ALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF
::::::::::::::::::::::::.::::::::::::
NP_000 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
190 200 210
>>NP_002050 (OMIM: 139240) growth hormone variant isofor (217 aa)
initn: 1129 init1: 1129 opt: 1129 Z-score: 1412.7 bits: 268.5 E(85289): 6e-72
Smith-Waterman score: 1129; 79.7% identity (92.6% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KB6 MAPGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEET
:: ::::::::::.:::: ::::..: :.:::::::.:::.:.: .::: ::::::::.
NP_002 MAAGSRTSLLLAFGLLCLSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFEEA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLR
:: :.::::::.. :::.:::.::::::: .:::::::::::::::::.::::::..::
NP_002 YILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHD
:.:::.::: .:::. :. :::::::::::: :::::: :::::..:.::::::.::: :
NP_002 SVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFDTKSHNDD
130 140 150 160 170 180
190 200 210
pF1KB6 ALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF
::::::::::::::::::::::::.::::::::::::
NP_002 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
190 200 210
>>NP_072170 (OMIM: 118820) chorionic somatomammotropin h (167 aa)
initn: 991 init1: 991 opt: 996 Z-score: 1248.9 bits: 237.8 E(85289): 7.9e-63
Smith-Waterman score: 996; 93.4% identity (94.0% similar) in 166 aa overlap (1-165:1-166)
10 20 30 40 50 60
pF1KB6 MAPGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEET
:: :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_072 YIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLR
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 SMFANNLVYDTSDSDDYHLLKDLEEGIQTLMG-RLEDGSRRTGQILKQTYSKFDTNSHNH
:::::::::::::::::::::::::::::::: :. : : :
NP_072 SMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGVRVAPGVANPGTPLA
130 140 150 160
180 190 200 210
pF1KB6 DALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF
>>NP_001307998 (OMIM: 603515) chorionic somatomammotropi (183 aa)
initn: 963 init1: 963 opt: 965 Z-score: 1209.7 bits: 230.7 E(85289): 1.2e-60
Smith-Waterman score: 1030; 77.9% identity (80.6% similar) in 217 aa overlap (1-217:1-183)
10 20 30 40 50 60
pF1KB6 MAPGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEET
:: :::::::::::::::::::: ::.
NP_001 MAAGSRTSLLLAFALLCLPWLQE----------------------------------EEA
10 20
70 80 90 100 110 120
pF1KB6 YIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLR
:: :.::::::::::::::::::::: :::::::::::::::.:::::::: ::::::::
NP_001 YITKEQKYSFLHDSQTSFCFSDSIPTSSNMEETQQKSNLELLHISLLLIESRLEPVRFLR
30 40 50 60 70 80
130 140 150 160 170 180
pF1KB6 SMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHD
: :.:::::::::::::::::::::::: :::::::::. ::: ::::::::::::::::
NP_001 STFTNNLVYDTSDSDDYHLLKDLEEGIQMLMGRLEDGSHLTGQTLKQTYSKFDTNSHNHD
90 100 110 120 130 140
190 200 210
pF1KB6 ALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF
:::::::::.:::::::::::::::::::::::::::
NP_001 ALLKNYGLLHCFRKDMDKVETFLRMVQCRSVEGSCGF
150 160 170 180
>>NP_001307996 (OMIM: 603515) chorionic somatomammotropi (162 aa)
initn: 957 init1: 957 opt: 957 Z-score: 1200.6 bits: 228.8 E(85289): 3.9e-60
Smith-Waterman score: 957; 91.8% identity (95.6% similar) in 159 aa overlap (59-217:4-162)
30 40 50 60 70 80
pF1KB6 TVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPS
:.:: :.::::::::::::::::::::: :
NP_001 MAAEAYITKEQKYSFLHDSQTSFCFSDSIPTSS
10 20 30
90 100 110 120 130 140
pF1KB6 NMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQ
::::::::::::::.:::::::: ::::::::: :.::::::::::::::::::::::::
NP_001 NMEETQQKSNLELLHISLLLIESRLEPVRFLRSTFTNNLVYDTSDSDDYHLLKDLEEGIQ
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 TLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQC
:::::::::. ::: :::::::::::::::::::::::::.::::::::::::::::::
NP_001 MLMGRLEDGSHLTGQTLKQTYSKFDTNSHNHDALLKNYGLLHCFRKDMDKVETFLRMVQC
100 110 120 130 140 150
210
pF1KB6 RSVEGSCGF
:::::::::
NP_001 RSVEGSCGF
160
>>XP_011522646 (OMIM: 603515) PREDICTED: chorionic somat (261 aa)
initn: 875 init1: 540 opt: 872 Z-score: 1091.6 bits: 209.3 E(85289): 4.6e-54
Smith-Waterman score: 872; 83.6% identity (87.7% similar) in 171 aa overlap (1-165:1-171)
10 20 30 40 50
pF1KB6 MAPGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEF---
:: ::::::::::::::::::::::::::::::::: .:::::::::::::::::::
XP_011 MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFKEAMLQAHRAHQLAIDTYQEFISS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 --EETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEP
:.:: :.::::::::::::::::::::: :::::::::::::::.:::::::: :::
XP_011 WGMEAYITKEQKYSFLHDSQTSFCFSDSIPTSSNMEETQQKSNLELLHISLLLIESRLEP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 VRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMG-RLEDGSRRTGQILKQTYSKFDT
:::::: :.:::::::::::::::::::::::: ::: :. : :. :
XP_011 VRFLRSTFTNNLVYDTSDSDDYHLLKDLEEGIQMLMGVRVAPGVPNPGSPLASRAGGEKH
130 140 150 160 170 180
180 190 200 210
pF1KB6 NSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF
XP_011 CCPLFSSQALTQENSPYSSFPLVNPPGLSLHPEGEGGKWINERGREQCPSAWSLLLLLHF
190 200 210 220 230 240
>>NP_072053 (OMIM: 139250,173100,262400,262650,612781) s (202 aa)
initn: 1131 init1: 837 opt: 837 Z-score: 1049.8 bits: 201.2 E(85289): 9.8e-52
Smith-Waterman score: 1105; 79.7% identity (88.0% similar) in 217 aa overlap (1-217:1-202)
10 20 30 40 50 60
pF1KB6 MAPGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEET
:: ::::::::::.:::::::::..: :.:::::::.:::.::: ::::.::::::
NP_072 MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEF---
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 YIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLR
. :::.:::.::::::: :::::::::::::::::::.::::::.:::
NP_072 ------------NPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLR
60 70 80 90 100
130 140 150 160 170 180
pF1KB6 SMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHD
:.:::.::: .:::. : :::::::::::::::::::: :::::.::::::::::::: :
NP_072 SVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDD
110 120 130 140 150 160
190 200 210
pF1KB6 ALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF
::::::::::::::::::::::::.::::::::::::
NP_072 ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
170 180 190 200
217 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 02:17:03 2016 done: Sat Nov 5 02:17:04 2016
Total Scan time: 6.110 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]