Result of FASTA (omim) for
pF1KB6973
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6973, 217 aa
1>>>pF1KB6973 217 - 217 aa - 217 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1284+/-0.000252; mu= 11.8994+/- 0.016
mean_var=99.8040+/-20.180, 0's: 0 Z-trim(123.3): 14 B-trim: 1380 in 1/60
Lambda= 0.128381
statistics sampled from 42961 (42978) to 42961 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.824), E-opt: 0.2 (0.504), width: 16
Scan time: 6.910
The best scores are: opt bits E(85289)
NP_056537 (OMIM: 604647) neuron-specific vesicular ( 217) 1493 285.6 4.4e-77
XP_011538138 (OMIM: 604647) PREDICTED: neuron-spec ( 250) 920 179.5 4.3e-45
XP_005252742 (OMIM: 604647) PREDICTED: neuron-spec ( 250) 920 179.5 4.3e-45
XP_011538140 (OMIM: 604647) PREDICTED: neuron-spec ( 130) 886 173.0 2e-43
NP_001308546 (OMIM: 604647) neuron-specific vesicu ( 135) 654 130.0 1.8e-30
NP_001274692 (OMIM: 607645) neuron-specific protei ( 185) 378 79.0 5.7e-15
XP_016863511 (OMIM: 607645) PREDICTED: neuron-spec ( 185) 378 79.0 5.7e-15
NP_001035190 (OMIM: 607645) neuron-specific protei ( 185) 378 79.0 5.7e-15
NP_055207 (OMIM: 607645) neuron-specific protein f ( 185) 378 79.0 5.7e-15
NP_001274693 (OMIM: 607645) neuron-specific protei ( 158) 299 64.3 1.3e-10
NP_057064 (OMIM: 616752) neuron-specific protein f ( 171) 211 48.0 1.1e-05
>>NP_056537 (OMIM: 604647) neuron-specific vesicular pro (217 aa)
initn: 1493 init1: 1493 opt: 1493 Z-score: 1504.9 bits: 285.6 E(85289): 4.4e-77
Smith-Waterman score: 1493; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KB6 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QQNFPDLEGQRLNCSHPEEGRRLPTARMIAFAMALLGCVLIMYKAIWYDQFTCPDGFLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QQNFPDLEGQRLNCSHPEEGRRLPTARMIAFAMALLGCVLIMYKAIWYDQFTCPDGFLLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 HKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEERKGPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEERKGPT
130 140 150 160 170 180
190 200 210
pF1KB6 QAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
:::::::::::::::::::::::::::::::::::::
NP_056 QAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
190 200 210
>>XP_011538138 (OMIM: 604647) PREDICTED: neuron-specific (250 aa)
initn: 1479 init1: 918 opt: 920 Z-score: 930.5 bits: 179.5 E(85289): 4.3e-45
Smith-Waterman score: 1410; 86.7% identity (86.7% similar) in 249 aa overlap (2-217:2-250)
10 20 30 40 50 60
pF1KB6 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
10 20 30 40 50 60
70 80
pF1KB6 QQNFPDLEGQRLNCSHPEEGRR---------------------------------LPTAR
:::::::::::::::::::::: :::::
XP_011 QQNFPDLEGQRLNCSHPEEGRRTDLLGLPAPGLTFQSAAHVTTHAPTVGSHLGGLLPTAR
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB6 MIAFAMALLGCVLIMYKAIWYDQFTCPDGFLLRHKICTPLTLEMYYTEMDPERHRSILAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIAFAMALLGCVLIMYKAIWYDQFTCPDGFLLRHKICTPLTLEMYYTEMDPERHRSILAA
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB6 IGAYPLSRKHGTETPAAWGDGYRAAKEERKGPTQAGAAAAATEPPGKPSAKAEKEAARKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGAYPLSRKHGTETPAAWGDGYRAAKEERKGPTQAGAAAAATEPPGKPSAKAEKEAARKA
190 200 210 220 230 240
210
pF1KB6 AGSAAPPPAQ
::::::::::
XP_011 AGSAAPPPAQ
250
>>XP_005252742 (OMIM: 604647) PREDICTED: neuron-specific (250 aa)
initn: 1479 init1: 918 opt: 920 Z-score: 930.5 bits: 179.5 E(85289): 4.3e-45
Smith-Waterman score: 1410; 86.7% identity (86.7% similar) in 249 aa overlap (2-217:2-250)
10 20 30 40 50 60
pF1KB6 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
10 20 30 40 50 60
70 80
pF1KB6 QQNFPDLEGQRLNCSHPEEGRR---------------------------------LPTAR
:::::::::::::::::::::: :::::
XP_005 QQNFPDLEGQRLNCSHPEEGRRTDLLGLPAPGLTFQSAAHVTTHAPTVGSHLGGLLPTAR
70 80 90 100 110 120
90 100 110 120 130 140
pF1KB6 MIAFAMALLGCVLIMYKAIWYDQFTCPDGFLLRHKICTPLTLEMYYTEMDPERHRSILAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIAFAMALLGCVLIMYKAIWYDQFTCPDGFLLRHKICTPLTLEMYYTEMDPERHRSILAA
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB6 IGAYPLSRKHGTETPAAWGDGYRAAKEERKGPTQAGAAAAATEPPGKPSAKAEKEAARKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGAYPLSRKHGTETPAAWGDGYRAAKEERKGPTQAGAAAAATEPPGKPSAKAEKEAARKA
190 200 210 220 230 240
210
pF1KB6 AGSAAPPPAQ
::::::::::
XP_005 AGSAAPPPAQ
250
>>XP_011538140 (OMIM: 604647) PREDICTED: neuron-specific (130 aa)
initn: 886 init1: 886 opt: 886 Z-score: 900.4 bits: 173.0 E(85289): 2e-43
Smith-Waterman score: 886; 100.0% identity (100.0% similar) in 130 aa overlap (88-217:1-130)
60 70 80 90 100 110
pF1KB6 SPDQQNFPDLEGQRLNCSHPEEGRRLPTARMIAFAMALLGCVLIMYKAIWYDQFTCPDGF
::::::::::::::::::::::::::::::
XP_011 MIAFAMALLGCVLIMYKAIWYDQFTCPDGF
10 20 30
120 130 140 150 160 170
pF1KB6 LLRHKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRHKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEERK
40 50 60 70 80 90
180 190 200 210
pF1KB6 GPTQAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
::::::::::::::::::::::::::::::::::::::::
XP_011 GPTQAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
100 110 120 130
>>NP_001308546 (OMIM: 604647) neuron-specific vesicular (135 aa)
initn: 654 init1: 654 opt: 654 Z-score: 668.0 bits: 130.0 E(85289): 1.8e-30
Smith-Waterman score: 654; 98.0% identity (99.0% similar) in 100 aa overlap (118-217:36-135)
90 100 110 120 130 140
pF1KB6 MIAFAMALLGCVLIMYKAIWYDQFTCPDGFLLRHKICTPLTLEMYYTEMDPERHRSILAA
: .:::::::::::::::::::::::::::
NP_001 TVRSVPNRRSGRAWARGAQEGSAPPTLTRPLPQHKICTPLTLEMYYTEMDPERHRSILAA
10 20 30 40 50 60
150 160 170 180 190 200
pF1KB6 IGAYPLSRKHGTETPAAWGDGYRAAKEERKGPTQAGAAAAATEPPGKPSAKAEKEAARKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGAYPLSRKHGTETPAAWGDGYRAAKEERKGPTQAGAAAAATEPPGKPSAKAEKEAARKA
70 80 90 100 110 120
210
pF1KB6 AGSAAPPPAQ
::::::::::
NP_001 AGSAAPPPAQ
130
>>NP_001274692 (OMIM: 607645) neuron-specific protein fa (185 aa)
initn: 319 init1: 165 opt: 378 Z-score: 389.8 bits: 79.0 E(85289): 5.7e-15
Smith-Waterman score: 378; 38.8% identity (68.8% similar) in 170 aa overlap (1-165:1-164)
10 20 30 40 50 60
pF1KB6 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
::::: .:. : :.: .:: .:..::..:::..::: : ::.::.::.:::. ::
NP_001 MVKLGNNFAEKGTKQPLLEDG--FDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYE---PD
10 20 30 40 50
70 80 90 100 110
pF1KB6 QQNFPDLEGQRLNCS-HPEEG--RRLPTARMIAFAMALLGCV--LIMYKAIWYDQFTCPD
... : . . :: .:. .. .. ::.:.: :: :..::. ::. .:::
NP_001 RKKGKARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDR-ACPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 GFLLRHKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEE
::.:.. : : :: ::.:.: .... ..:. : :... :.. . :
NP_001 GFVLKNTQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLS
120 130 140 150 160 170
180 190 200 210
pF1KB6 RKGPTQAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
NP_001 EQETEAAEKSA
180
>>XP_016863511 (OMIM: 607645) PREDICTED: neuron-specific (185 aa)
initn: 319 init1: 165 opt: 378 Z-score: 389.8 bits: 79.0 E(85289): 5.7e-15
Smith-Waterman score: 378; 38.8% identity (68.8% similar) in 170 aa overlap (1-165:1-164)
10 20 30 40 50 60
pF1KB6 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
::::: .:. : :.: .:: .:..::..:::..::: : ::.::.::.:::. ::
XP_016 MVKLGNNFAEKGTKQPLLEDG--FDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYE---PD
10 20 30 40 50
70 80 90 100 110
pF1KB6 QQNFPDLEGQRLNCS-HPEEG--RRLPTARMIAFAMALLGCV--LIMYKAIWYDQFTCPD
... : . . :: .:. .. .. ::.:.: :: :..::. ::. .:::
XP_016 RKKGKARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDR-ACPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 GFLLRHKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEE
::.:.. : : :: ::.:.: .... ..:. : :... :.. . :
XP_016 GFVLKNTQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLS
120 130 140 150 160 170
180 190 200 210
pF1KB6 RKGPTQAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
XP_016 EQETEAAEKSA
180
>>NP_001035190 (OMIM: 607645) neuron-specific protein fa (185 aa)
initn: 319 init1: 165 opt: 378 Z-score: 389.8 bits: 79.0 E(85289): 5.7e-15
Smith-Waterman score: 378; 38.8% identity (68.8% similar) in 170 aa overlap (1-165:1-164)
10 20 30 40 50 60
pF1KB6 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
::::: .:. : :.: .:: .:..::..:::..::: : ::.::.::.:::. ::
NP_001 MVKLGNNFAEKGTKQPLLEDG--FDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYE---PD
10 20 30 40 50
70 80 90 100 110
pF1KB6 QQNFPDLEGQRLNCS-HPEEG--RRLPTARMIAFAMALLGCV--LIMYKAIWYDQFTCPD
... : . . :: .:. .. .. ::.:.: :: :..::. ::. .:::
NP_001 RKKGKARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDR-ACPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 GFLLRHKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEE
::.:.. : : :: ::.:.: .... ..:. : :... :.. . :
NP_001 GFVLKNTQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLS
120 130 140 150 160 170
180 190 200 210
pF1KB6 RKGPTQAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
NP_001 EQETEAAEKSA
180
>>NP_055207 (OMIM: 607645) neuron-specific protein famil (185 aa)
initn: 319 init1: 165 opt: 378 Z-score: 389.8 bits: 79.0 E(85289): 5.7e-15
Smith-Waterman score: 378; 38.8% identity (68.8% similar) in 170 aa overlap (1-165:1-164)
10 20 30 40 50 60
pF1KB6 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
::::: .:. : :.: .:: .:..::..:::..::: : ::.::.::.:::. ::
NP_055 MVKLGNNFAEKGTKQPLLEDG--FDTIPLMTPLDVNQLQFPPPDKVVVKTKTEYE---PD
10 20 30 40 50
70 80 90 100 110
pF1KB6 QQNFPDLEGQRLNCS-HPEEG--RRLPTARMIAFAMALLGCV--LIMYKAIWYDQFTCPD
... : . . :: .:. .. .. ::.:.: :: :..::. ::. .:::
NP_055 RKKGKARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDR-ACPD
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 GFLLRHKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEE
::.:.. : : :: ::.:.: .... ..:. : :... :.. . :
NP_055 GFVLKNTQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLS
120 130 140 150 160 170
180 190 200 210
pF1KB6 RKGPTQAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
NP_055 EQETEAAEKSA
180
>>NP_001274693 (OMIM: 607645) neuron-specific protein fa (158 aa)
initn: 267 init1: 146 opt: 299 Z-score: 311.7 bits: 64.3 E(85289): 1.3e-10
Smith-Waterman score: 299; 36.9% identity (68.1% similar) in 141 aa overlap (30-165:1-137)
10 20 30 40 50 60
pF1KB6 MVKLGCSFSGKPGKDPGDQDGAAMDSVPLISPLDISQLQPPLPDQVVIKTQTEYQLSSPD
..:::..::: : ::.::.::.:::. ::
NP_001 MTPLDVNQLQFPPPDKVVVKTKTEYE---PD
10 20
70 80 90 100 110
pF1KB6 QQNFPDLEGQRLNCS-HPEEG--RRLPTARMIAFAMALLGCV--LIMYKAIWYDQFTCPD
... : . . :: .:. .. .. ::.:.: :: :..::. ::. .:::
NP_001 RKKGKARPPQIAEFTVSITEGVTERFKVSVLVLFALAFLTCVVFLVVYKVYKYDR-ACPD
30 40 50 60 70 80
120 130 140 150 160 170
pF1KB6 GFLLRHKICTPLTLEMYYTEMDPERHRSILAAIGAYPLSRKHGTETPAAWGDGYRAAKEE
::.:.. : : :: ::.:.: .... ..:. : :... :.. . :
NP_001 GFVLKNTQCIPEGLESYYAEQDSSAREKFYTVINHYNLAKQSITRSVSPWMSVLSEEKLS
90 100 110 120 130 140
180 190 200 210
pF1KB6 RKGPTQAGAAAAATEPPGKPSAKAEKEAARKAAGSAAPPPAQ
NP_001 EQETEAAEKSA
150
217 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:59:26 2016 done: Fri Nov 4 10:59:27 2016
Total Scan time: 6.910 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]