Result of FASTA (ccds) for
pF1KB6889
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6889, 183 aa
1>>>pF1KB6889 183 - 183 aa - 183 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1917+/-0.000951; mu= 13.4693+/- 0.058
mean_var=70.6568+/-14.325, 0's: 0 Z-trim(106.6): 199 B-trim: 586 in 2/49
Lambda= 0.152580
statistics sampled from 8845 (9075) to 8845 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.279), width: 16
Scan time: 1.840
The best scores are: opt bits E(32554)
CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 ( 183) 1196 272.1 1.4e-73
CCDS9485.1 RAP2A gene_id:5911|Hs108|chr13 ( 183) 1089 248.5 1.7e-66
CCDS14632.1 RAP2C gene_id:57826|Hs108|chrX ( 183) 1050 239.9 6.5e-64
CCDS8984.1 RAP1B gene_id:5908|Hs108|chr12 ( 184) 741 171.9 2e-43
CCDS840.1 RAP1A gene_id:5906|Hs108|chr1 ( 184) 737 171.0 3.6e-43
CCDS76024.1 RAP2C gene_id:57826|Hs108|chrX ( 117) 641 149.8 5.8e-37
CCDS1123.1 RIT1 gene_id:6016|Hs108|chr1 ( 219) 573 135.0 3e-32
CCDS58037.1 RIT1 gene_id:6016|Hs108|chr1 ( 236) 573 135.0 3.2e-32
CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 ( 188) 568 133.8 5.8e-32
CCDS877.1 NRAS gene_id:4893|Hs108|chr1 ( 189) 568 133.8 5.8e-32
CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 ( 189) 565 133.2 9.2e-32
CCDS11921.1 RIT2 gene_id:6014|Hs108|chr18 ( 217) 560 132.1 2.2e-31
CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 ( 189) 553 130.5 5.7e-31
CCDS7814.1 RRAS2 gene_id:22800|Hs108|chr11 ( 204) 539 127.5 5.2e-30
CCDS5460.1 RALA gene_id:5898|Hs108|chr7 ( 206) 533 126.2 1.3e-29
CCDS2131.1 RALB gene_id:5899|Hs108|chr2 ( 206) 524 124.2 5.1e-29
CCDS7699.1 HRAS gene_id:3265|Hs108|chr11 ( 170) 521 123.5 7e-29
CCDS6687.1 DIRAS2 gene_id:54769|Hs108|chr9 ( 199) 515 122.2 2e-28
CCDS3100.1 MRAS gene_id:22808|Hs108|chr3 ( 208) 513 121.8 2.8e-28
CCDS12774.1 RRAS gene_id:6237|Hs108|chr19 ( 218) 511 121.3 3.9e-28
CCDS12092.1 DIRAS1 gene_id:148252|Hs108|chr19 ( 198) 504 119.8 1.1e-27
CCDS58036.1 RIT1 gene_id:6016|Hs108|chr1 ( 183) 480 114.4 3.8e-26
CCDS62431.1 RIT2 gene_id:6014|Hs108|chr18 ( 153) 457 109.3 1.1e-24
CCDS5927.1 RHEB gene_id:6009|Hs108|chr7 ( 184) 441 105.9 1.5e-23
CCDS8673.1 RERG gene_id:85004|Hs108|chr12 ( 199) 440 105.7 1.8e-23
CCDS53603.1 RRAS2 gene_id:22800|Hs108|chr11 ( 169) 432 103.9 5.5e-23
CCDS58253.1 RAP1B gene_id:5908|Hs108|chr12 ( 165) 431 103.6 6.3e-23
CCDS58254.1 RAP1B gene_id:5908|Hs108|chr12 ( 142) 425 102.3 1.4e-22
CCDS8778.1 RHEBL1 gene_id:121268|Hs108|chr12 ( 183) 422 101.7 2.7e-22
CCDS641.1 DIRAS3 gene_id:9077|Hs108|chr1 ( 229) 370 90.3 8.9e-19
CCDS46306.1 RAB1A gene_id:5861|Hs108|chr2 ( 205) 367 89.6 1.3e-18
CCDS11703.1 RAB37 gene_id:326624|Hs108|chr17 ( 216) 361 88.3 3.4e-18
CCDS82198.1 RAB37 gene_id:326624|Hs108|chr17 ( 196) 360 88.1 3.6e-18
CCDS32722.1 RAB37 gene_id:326624|Hs108|chr17 ( 223) 360 88.1 4e-18
CCDS54161.1 RAB37 gene_id:326624|Hs108|chr17 ( 228) 360 88.1 4.1e-18
CCDS35246.1 ERAS gene_id:3266|Hs108|chrX ( 233) 360 88.1 4.2e-18
CCDS13181.1 REM1 gene_id:28954|Hs108|chr20 ( 298) 353 86.6 1.5e-17
CCDS31613.1 RAB1B gene_id:81876|Hs108|chr11 ( 201) 350 85.9 1.7e-17
CCDS14766.1 RAB39B gene_id:116442|Hs108|chrX ( 213) 347 85.2 2.8e-17
CCDS10460.1 RAB26 gene_id:25837|Hs108|chr16 ( 256) 346 85.1 3.8e-17
CCDS8900.1 RAB5B gene_id:5869|Hs108|chr12 ( 215) 345 84.8 3.9e-17
CCDS14156.1 RAB9A gene_id:9367|Hs108|chrX ( 201) 339 83.4 9.1e-17
CCDS10200.1 RASL12 gene_id:51285|Hs108|chr15 ( 266) 338 83.3 1.3e-16
CCDS2520.1 RAB17 gene_id:64284|Hs108|chr2 ( 212) 336 82.8 1.5e-16
CCDS2633.1 RAB5A gene_id:5868|Hs108|chr3 ( 215) 336 82.8 1.5e-16
CCDS9003.1 RAB21 gene_id:23011|Hs108|chr12 ( 225) 336 82.8 1.6e-16
CCDS3082.1 RAB6B gene_id:51560|Hs108|chr3 ( 208) 334 82.3 2e-16
CCDS11419.1 RAB5C gene_id:5878|Hs108|chr17 ( 216) 334 82.4 2.1e-16
CCDS58551.1 RAB5C gene_id:5878|Hs108|chr17 ( 249) 334 82.4 2.3e-16
CCDS8223.1 RAB6A gene_id:5870|Hs108|chr11 ( 208) 332 81.9 2.7e-16
>>CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 (183 aa)
initn: 1196 init1: 1196 opt: 1196 Z-score: 1434.6 bits: 272.1 E(32554): 1.4e-73
Smith-Waterman score: 1196; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)
10 20 30 40 50 60
pF1KB6 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSAC
130 140 150 160 170 180
pF1KB6 VIL
:::
CCDS31 VIL
>>CCDS9485.1 RAP2A gene_id:5911|Hs108|chr13 (183 aa)
initn: 1106 init1: 1089 opt: 1089 Z-score: 1307.3 bits: 248.5 E(32554): 1.7e-66
Smith-Waterman score: 1089; 91.2% identity (97.3% similar) in 182 aa overlap (1-182:1-182)
10 20 30 40 50 60
pF1KB6 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
CCDS94 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL
:::::::::::::::::::::::::::::::::::::::::::::::.::.:::::::::
CCDS94 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSAC
:.::::: .::.::::::.:::::::::.:. ::::::::::::::::::. :. :::::
CCDS94 ESEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQMNYAAQPDKDDPCCSAC
130 140 150 160 170 180
pF1KB6 VIL
:
CCDS94 NIQ
>>CCDS14632.1 RAP2C gene_id:57826|Hs108|chrX (183 aa)
initn: 1067 init1: 1050 opt: 1050 Z-score: 1260.9 bits: 239.9 E(32554): 6.5e-64
Smith-Waterman score: 1050; 86.3% identity (96.2% similar) in 182 aa overlap (1-182:1-182)
10 20 30 40 50 60
pF1KB6 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
CCDS14 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL
::::::::::::::::::::::::::::::::::::::::.::::::.::.:::::::::
CCDS14 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSAC
: :::: .::.:::.::.:::::::::.:. ::::::::::::::.. :. .. ::..:
CCDS14 EPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQMNYSSLPEKQDQCCTTC
130 140 150 160 170 180
pF1KB6 VIL
:.
CCDS14 VVQ
>>CCDS8984.1 RAP1B gene_id:5908|Hs108|chr12 (184 aa)
initn: 696 init1: 634 opt: 741 Z-score: 893.3 bits: 171.9 E(32554): 2e-43
Smith-Waterman score: 741; 61.4% identity (82.6% similar) in 184 aa overlap (1-183:1-184)
10 20 30 40 50 60
pF1KB6 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
:::::.:::::::::::::::::: : :.::::::::: :::..:::.. .::::::::
CCDS89 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL
::::..:::::.:::::: ::::.. :..:.:.. .:.::.::: . ::::::::: ::
CCDS89 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 EGEREVSYGEGKALAEEWS-CPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSA
: :: :. .:. ::..:. : :.:.:::.: .:.:.: ..:::.: . : :.
CCDS89 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
130 140 150 160 170 180
180
pF1KB6 CVIL
: .:
CCDS89 CQLL
>>CCDS840.1 RAP1A gene_id:5906|Hs108|chr1 (184 aa)
initn: 697 init1: 635 opt: 737 Z-score: 888.5 bits: 171.0 E(32554): 3.6e-43
Smith-Waterman score: 737; 60.9% identity (83.2% similar) in 184 aa overlap (1-183:1-184)
10 20 30 40 50 60
pF1KB6 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
:::::.:::::::::::::::::: : :.::::::::: :::..::: . .::::::::
CCDS84 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL
::::..:::::.:::::: ::::.. :..:.:.. .:.::.::: : ::::::::: ::
CCDS84 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 EGEREVSYGEGKALAEEW-SCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSA
: :: :. .:. ::..: .: :.:.:::.: .:.:.: ..:::.: . . . ..
CCDS84 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
130 140 150 160 170 180
180
pF1KB6 CVIL
:..:
CCDS84 CLLL
>>CCDS76024.1 RAP2C gene_id:57826|Hs108|chrX (117 aa)
initn: 657 init1: 641 opt: 641 Z-score: 777.1 bits: 149.8 E(32554): 5.8e-37
Smith-Waterman score: 641; 79.3% identity (94.0% similar) in 116 aa overlap (67-182:1-116)
40 50 60 70 80 90
pF1KB6 EDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPM
::::::::::::::::::::::::::::::
CCDS76 MRDLYIKNGQGFILVYSLVNQQSFQDIKPM
10 20 30
100 110 120 130 140 150
pF1KB6 RDQIIRVKRYERVPMILVGNKVDLEGEREVSYGEGKALAEEWSCPFMETSAKNKASVDEL
::::.::::::.::.:::::::::: :::: .::.:::.::.:::::::::.:. ::::
CCDS76 RDQIVRVKRYEKVPLILVGNKVDLEPEREVMSSEGRALAQEWGCPFMETSAKSKSMVDEL
40 50 60 70 80 90
160 170 180
pF1KB6 FAEIVRQMNYAAQPNGDEGCCSACVIL
::::::::::.. :. .. ::..::.
CCDS76 FAEIVRQMNYSSLPEKQDQCCTTCVVQ
100 110
>>CCDS1123.1 RIT1 gene_id:6016|Hs108|chr1 (219 aa)
initn: 596 init1: 573 opt: 573 Z-score: 692.3 bits: 135.0 E(32554): 3e-32
Smith-Waterman score: 573; 49.7% identity (81.6% similar) in 163 aa overlap (2-164:20-182)
10 20 30 40
pF1KB6 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRK
::::.:.::.:::::::.:.::.. : : .:::::: :.
CCDS11 MDSGTRPVGSCCSSPAGLSREYKLVMLGAGGVGKSAMTMQFISHRFPEDHDPTIEDAYKI
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 EIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIR
.:..:. :. :.:::::: .:..::: :.. :.:::. ::.....::.... ... : :
CCDS11 RIRIDDEPANLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFHEVREFKQLIYR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 VKRYERVPMILVGNKVDLEGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVR
:.: . .:..::::: ::. :.:. :: :::.:.::::.:::: . .:..: .::
CCDS11 VRRTDDTPVVLVGNKSDLKQLRQVTKEEGLALAREFSCPFFETSAAYRYYIDDVFHALVR
130 140 150 160 170 180
170 180
pF1KB6 QMNYAAQPNGDEGCCSACVIL
..
CCDS11 EIRRKEKEAVLAMEKKSKPKNSVWKRLKSPFRKKKDSVT
190 200 210
>>CCDS58037.1 RIT1 gene_id:6016|Hs108|chr1 (236 aa)
initn: 596 init1: 573 opt: 573 Z-score: 691.9 bits: 135.0 E(32554): 3.2e-32
Smith-Waterman score: 573; 49.7% identity (81.6% similar) in 163 aa overlap (2-164:37-199)
10 20 30
pF1KB6 MREYKVVVLGSGGVGKSALTVQFVTGSFIEK
::::.:.::.:::::::.:.::.. : :
CCDS58 LGATEEGPKRTMDSGTRPVGSCCSSPAGLSREYKLVMLGAGGVGKSAMTMQFISHRFPED
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 YDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQ
.:::::: :. .:..:. :. :.:::::: .:..::: :.. :.:::. ::.....::.
CCDS58 HDPTIEDAYKIRIRIDDEPANLDILDTAGQAEFTAMRDQYMRAGEGFIICYSITDRRSFH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 DIKPMRDQIIRVKRYERVPMILVGNKVDLEGEREVSYGEGKALAEEWSCPFMETSAKNKA
... ... : ::.: . .:..::::: ::. :.:. :: :::.:.::::.:::: .
CCDS58 EVREFKQLIYRVRRTDDTPVVLVGNKSDLKQLRQVTKEEGLALAREFSCPFFETSAAYRY
130 140 150 160 170 180
160 170 180
pF1KB6 SVDELFAEIVRQMNYAAQPNGDEGCCSACVIL
.:..: .::..
CCDS58 YIDDVFHALVREIRRKEKEAVLAMEKKSKPKNSVWKRLKSPFRKKKDSVT
190 200 210 220 230
>>CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 (188 aa)
initn: 555 init1: 475 opt: 568 Z-score: 687.3 bits: 133.8 E(32554): 5.8e-32
Smith-Waterman score: 568; 46.0% identity (75.1% similar) in 189 aa overlap (1-183:1-188)
10 20 30 40 50 60
pF1KB6 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
: :::.::.:.:::::::::.:.. . :...::::::: :::.. .:. .:.::::::
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL
:....::: :...:.::. :... : .::.::. .:.:: ::: : :::.::::: ::
CCDS87 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 EGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEG-----
. : :. ... ::. .. ::.:::::.. .::. : .::.. . . .:
CCDS87 PS-RTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKK
130 140 150 160 170
180
pF1KB6 -CCSACVIL
. :::.
CCDS87 KSKTKCVIM
180
>>CCDS877.1 NRAS gene_id:4893|Hs108|chr1 (189 aa)
initn: 542 init1: 467 opt: 568 Z-score: 687.3 bits: 133.8 E(32554): 5.8e-32
Smith-Waterman score: 568; 45.3% identity (76.3% similar) in 190 aa overlap (1-183:1-189)
10 20 30 40 50 60
pF1KB6 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
: :::.::.:.:::::::::.:.. . :...::::::: :::.. .:. .:.::::::
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL
:....::: :...:.::. :... :..:: ::. .:.:: ::: . :::.::::: ::
CCDS87 QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 EGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQM------NYAAQPNGDE
: :. ... ::. .. ::.:::::.. .:.. : .::.. . .. .: .
CCDS87 P-TRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQ
130 140 150 160 170
180
pF1KB6 GCCS-ACVIL
:: . ::..
CCDS87 GCMGLPCVVM
180
183 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 00:19:27 2016 done: Sat Nov 5 00:19:28 2016
Total Scan time: 1.840 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]