FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6887, 183 aa 1>>>pF1KB6887 183 - 183 aa - 183 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4100+/-0.000283; mu= 9.6063+/- 0.018 mean_var=123.6577+/-24.837, 0's: 0 Z-trim(122.5): 9 B-trim: 2170 in 1/51 Lambda= 0.115336 statistics sampled from 40614 (40623) to 40614 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.476), width: 16 Scan time: 6.300 The best scores are: opt bits E(85289) XP_011539778 (OMIM: 156790) PREDICTED: microfibril ( 183) 1313 228.3 5.5e-60 NP_059453 (OMIM: 156790) microfibrillar-associated ( 183) 1313 228.3 5.5e-60 NP_002394 (OMIM: 156790) microfibrillar-associated ( 183) 1313 228.3 5.5e-60 NP_001128720 (OMIM: 156790) microfibrillar-associa ( 182) 1296 225.4 3.9e-59 NP_001128719 (OMIM: 156790) microfibrillar-associa ( 182) 1296 225.4 3.9e-59 NP_001284639 (OMIM: 601103,616166) microfibrillar- ( 151) 293 58.5 5.9e-09 NP_001284638 (OMIM: 601103,616166) microfibrillar- ( 163) 293 58.5 6.3e-09 NP_001284640 (OMIM: 601103,616166) microfibrillar- ( 148) 287 57.5 1.2e-08 NP_003471 (OMIM: 601103,616166) microfibrillar-ass ( 173) 283 56.8 2.1e-08 >>XP_011539778 (OMIM: 156790) PREDICTED: microfibrillar- (183 aa) initn: 1313 init1: 1313 opt: 1313 Z-score: 1197.9 bits: 228.3 E(85289): 5.5e-60 Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183) 10 20 30 40 50 60 pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC 130 140 150 160 170 180 pF1KB6 GSC ::: XP_011 GSC >>NP_059453 (OMIM: 156790) microfibrillar-associated pro (183 aa) initn: 1313 init1: 1313 opt: 1313 Z-score: 1197.9 bits: 228.3 E(85289): 5.5e-60 Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183) 10 20 30 40 50 60 pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_059 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_059 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_059 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC 130 140 150 160 170 180 pF1KB6 GSC ::: NP_059 GSC >>NP_002394 (OMIM: 156790) microfibrillar-associated pro (183 aa) initn: 1313 init1: 1313 opt: 1313 Z-score: 1197.9 bits: 228.3 E(85289): 5.5e-60 Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183) 10 20 30 40 50 60 pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC 130 140 150 160 170 180 pF1KB6 GSC ::: NP_002 GSC >>NP_001128720 (OMIM: 156790) microfibrillar-associated (182 aa) initn: 1230 init1: 1230 opt: 1296 Z-score: 1182.6 bits: 225.4 E(85289): 3.9e-59 Smith-Waterman score: 1296; 99.5% identity (99.5% similar) in 183 aa overlap (1-183:1-182) 10 20 30 40 50 60 pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRAAYLFLLFLP-GLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC 120 130 140 150 160 170 pF1KB6 GSC ::: NP_001 GSC 180 >>NP_001128719 (OMIM: 156790) microfibrillar-associated (182 aa) initn: 1230 init1: 1230 opt: 1296 Z-score: 1182.6 bits: 225.4 E(85289): 3.9e-59 Smith-Waterman score: 1296; 99.5% identity (99.5% similar) in 183 aa overlap (1-183:1-182) 10 20 30 40 50 60 pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE :::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRAAYLFLLFLP-GLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC 120 130 140 150 160 170 pF1KB6 GSC ::: NP_001 GSC 180 >>NP_001284639 (OMIM: 601103,616166) microfibrillar-asso (151 aa) initn: 301 init1: 288 opt: 293 Z-score: 281.7 bits: 58.5 E(85289): 5.9e-09 Smith-Waterman score: 293; 51.4% identity (80.0% similar) in 70 aa overlap (85-154:51-119) 60 70 80 90 100 110 pF1KB6 PRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPC :.. :. :.: .:.. ::::::.::: NP_001 DVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDD-LECWDEKFTCTRLYSVHRPV 30 40 50 60 70 120 130 140 150 160 170 pF1KB6 KQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAA :::....:: ::::.:..::::: : :: ..: .. .::: NP_001 KQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPP 80 90 100 110 120 130 180 pF1KB6 SCARSCGSC NP_001 CENVDLQRPNGL 140 150 >>NP_001284638 (OMIM: 601103,616166) microfibrillar-asso (163 aa) initn: 302 init1: 288 opt: 293 Z-score: 281.3 bits: 58.5 E(85289): 6.3e-09 Smith-Waterman score: 293; 51.4% identity (80.0% similar) in 70 aa overlap (85-154:63-131) 60 70 80 90 100 110 pF1KB6 PRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPC :.. :. :.: .:.. ::::::.::: NP_001 DVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDD-LECWDEKFTCTRLYSVHRPV 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB6 KQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAA :::....:: ::::.:..::::: : :: ..: .. .::: NP_001 KQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPP 100 110 120 130 140 150 180 pF1KB6 SCARSCGSC NP_001 CENVDLQRPNGL 160 >>NP_001284640 (OMIM: 601103,616166) microfibrillar-asso (148 aa) initn: 297 init1: 283 opt: 287 Z-score: 276.4 bits: 57.5 E(85289): 1.2e-08 Smith-Waterman score: 287; 44.4% identity (68.9% similar) in 90 aa overlap (65-154:29-116) 40 50 60 70 80 90 pF1KB6 YTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGP : ..: : . : : : .:. NP_001 MSLLGPKVLLFLAAFIITSDWIPLGVNSQRGDDVTQ-ATPETFTEDPNLVNDPATD-E 10 20 30 40 50 100 110 120 130 140 150 pF1KB6 LDCREEQYPCTRLYSIHRPCKQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCR .: .:.. ::::::.::: :::....:: ::::.:..::::: : :: ..: .. .::: NP_001 TECWDEKFTCTRLYSVHRPVKQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCR 60 70 80 90 100 110 160 170 180 pF1KB6 DKFSKCGVMASSGLCQSVAASCARSCGSC NP_001 QMAGLPPRRLRRSNYFRLPPCENVDLQRPNGL 120 130 140 >>NP_003471 (OMIM: 601103,616166) microfibrillar-associa (173 aa) initn: 297 init1: 283 opt: 283 Z-score: 271.9 bits: 56.8 E(85289): 2.1e-08 Smith-Waterman score: 283; 55.9% identity (84.7% similar) in 59 aa overlap (96-154:83-141) 70 80 90 100 110 120 pF1KB6 SQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNEVCFYS .: .:.. ::::::.::: :::....:: : NP_003 ATDETVLAVLADIAPSTDDLASLSEKNTTAECWDEKFTCTRLYSVHRPVKQCIHQLCFTS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 LRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC :::.:..::::: : :: ..: .. .::: NP_003 LRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENVDLQRPNG 120 130 140 150 160 170 183 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:12:22 2016 done: Sat Nov 5 00:12:23 2016 Total Scan time: 6.300 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]