Result of FASTA (omim) for
pF1KB6875
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6875, 159 aa
1>>>pF1KB6875 159 - 159 aa - 159 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1493+/-0.000319; mu= 11.9238+/- 0.020
mean_var=53.5681+/-10.951, 0's: 0 Z-trim(114.8): 29 B-trim: 1224 in 1/50
Lambda= 0.175235
statistics sampled from 24898 (24928) to 24898 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.292), width: 16
Scan time: 4.730
The best scores are: opt bits E(85289)
NP_000568 (OMIM: 137215,147679,612628,612852) inte ( 159) 1079 280.4 8.4e-76
NP_776214 (OMIM: 137215,147679,612628,612852) inte ( 177) 1062 276.1 1.8e-74
NP_776213 (OMIM: 137215,147679,612628,612852) inte ( 180) 1062 276.1 1.8e-74
NP_776215 (OMIM: 137215,147679,612628,612852) inte ( 143) 974 253.8 7.5e-68
NP_001305843 (OMIM: 137215,147679,612628,612852) i ( 143) 974 253.8 7.5e-68
XP_011509423 (OMIM: 137215,147679,612628,612852) P ( 143) 974 253.8 7.5e-68
XP_005263718 (OMIM: 137215,147679,612628,612852) P ( 143) 974 253.8 7.5e-68
NP_036407 (OMIM: 605507,614204) interleukin-36 rec ( 155) 414 112.3 3.3e-25
NP_775262 (OMIM: 605507,614204) interleukin-36 rec ( 155) 414 112.3 3.3e-25
NP_775184 (OMIM: 615296) interleukin-1 family memb ( 152) 322 89.0 3.3e-18
NP_115945 (OMIM: 615296) interleukin-1 family memb ( 152) 322 89.0 3.3e-18
XP_011509267 (OMIM: 605509) PREDICTED: interleukin ( 158) 236 67.3 1.2e-11
XP_005263696 (OMIM: 605509) PREDICTED: interleukin ( 158) 236 67.3 1.2e-11
NP_055255 (OMIM: 605509) interleukin-36 alpha [Hom ( 158) 236 67.3 1.2e-11
XP_016859295 (OMIM: 605509) PREDICTED: interleukin ( 158) 236 67.3 1.2e-11
NP_775270 (OMIM: 605508) interleukin-36 beta isofo ( 157) 218 62.7 2.8e-10
XP_011509264 (OMIM: 605508) PREDICTED: interleukin ( 157) 218 62.7 2.8e-10
NP_062564 (OMIM: 605542) interleukin-36 gamma isof ( 169) 211 61.0 1e-09
NP_001265497 (OMIM: 605542) interleukin-36 gamma i ( 134) 204 59.2 2.8e-09
NP_775295 (OMIM: 605510) interleukin-37 isoform 3 ( 157) 193 56.4 2.2e-08
NP_775296 (OMIM: 605510) interleukin-37 isoform 4 ( 178) 193 56.4 2.5e-08
XP_011509266 (OMIM: 605510) PREDICTED: interleukin ( 178) 193 56.4 2.5e-08
NP_775297 (OMIM: 605510) interleukin-37 isoform 5 ( 192) 193 56.4 2.7e-08
NP_775294 (OMIM: 605510) interleukin-37 isoform 2 ( 197) 193 56.4 2.7e-08
XP_011509265 (OMIM: 605510) PREDICTED: interleukin ( 218) 193 56.5 3e-08
NP_055254 (OMIM: 605510) interleukin-37 isoform 1 ( 218) 193 56.5 3e-08
XP_016859477 (OMIM: 137215,147720) PREDICTED: inte ( 238) 184 54.2 1.6e-07
NP_000567 (OMIM: 137215,147720) interleukin-1 beta ( 269) 184 54.2 1.7e-07
>>NP_000568 (OMIM: 137215,147679,612628,612852) interleu (159 aa)
initn: 1079 init1: 1079 opt: 1079 Z-score: 1481.9 bits: 280.4 E(85289): 8.4e-76
Smith-Waterman score: 1079; 100.0% identity (100.0% similar) in 159 aa overlap (1-159:1-159)
10 20 30 40 50 60
pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES
70 80 90 100 110 120
130 140 150
pF1KB6 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
:::::::::::::::::::::::::::::::::::::::
NP_000 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
130 140 150
>>NP_776214 (OMIM: 137215,147679,612628,612852) interleu (177 aa)
initn: 1062 init1: 1062 opt: 1062 Z-score: 1457.9 bits: 276.1 E(85289): 1.8e-74
Smith-Waterman score: 1062; 100.0% identity (100.0% similar) in 156 aa overlap (4-159:22-177)
10 20 30 40
pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYL
:::::::::::::::::::::::::::::::::::::::
NP_776 MEICRGLRSHLITLLLFLFHSETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 QGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_776 QGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQD
70 80 90 100 110 120
110 120 130 140 150
pF1KB6 KRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_776 KRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
130 140 150 160 170
>>NP_776213 (OMIM: 137215,147679,612628,612852) interleu (180 aa)
initn: 1062 init1: 1062 opt: 1062 Z-score: 1457.8 bits: 276.1 E(85289): 1.8e-74
Smith-Waterman score: 1062; 100.0% identity (100.0% similar) in 156 aa overlap (4-159:25-180)
10 20 30
pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVA
::::::::::::::::::::::::::::::::::::
NP_776 MALADLYEEGGGGGGEGEDNADSKETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 GYLQGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_776 GYLQGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENR
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 KQDKRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_776 KQDKRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
130 140 150 160 170 180
>>NP_776215 (OMIM: 137215,147679,612628,612852) interleu (143 aa)
initn: 974 init1: 974 opt: 974 Z-score: 1339.2 bits: 253.8 E(85289): 7.5e-68
Smith-Waterman score: 974; 100.0% identity (100.0% similar) in 143 aa overlap (17-159:1-143)
10 20 30 40 50 60
pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP
::::::::::::::::::::::::::::::::::::::::::::
NP_776 MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP
10 20 30 40
70 80 90 100 110 120
pF1KB6 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_776 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES
50 60 70 80 90 100
130 140 150
pF1KB6 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
:::::::::::::::::::::::::::::::::::::::
NP_776 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
110 120 130 140
>>NP_001305843 (OMIM: 137215,147679,612628,612852) inter (143 aa)
initn: 974 init1: 974 opt: 974 Z-score: 1339.2 bits: 253.8 E(85289): 7.5e-68
Smith-Waterman score: 974; 100.0% identity (100.0% similar) in 143 aa overlap (17-159:1-143)
10 20 30 40 50 60
pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP
::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP
10 20 30 40
70 80 90 100 110 120
pF1KB6 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES
50 60 70 80 90 100
130 140 150
pF1KB6 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
:::::::::::::::::::::::::::::::::::::::
NP_001 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
110 120 130 140
>>XP_011509423 (OMIM: 137215,147679,612628,612852) PREDI (143 aa)
initn: 974 init1: 974 opt: 974 Z-score: 1339.2 bits: 253.8 E(85289): 7.5e-68
Smith-Waterman score: 974; 100.0% identity (100.0% similar) in 143 aa overlap (17-159:1-143)
10 20 30 40 50 60
pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP
::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP
10 20 30 40
70 80 90 100 110 120
pF1KB6 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES
50 60 70 80 90 100
130 140 150
pF1KB6 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
:::::::::::::::::::::::::::::::::::::::
XP_011 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
110 120 130 140
>>XP_005263718 (OMIM: 137215,147679,612628,612852) PREDI (143 aa)
initn: 974 init1: 974 opt: 974 Z-score: 1339.2 bits: 253.8 E(85289): 7.5e-68
Smith-Waterman score: 974; 100.0% identity (100.0% similar) in 143 aa overlap (17-159:1-143)
10 20 30 40 50 60
pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP
::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP
10 20 30 40
70 80 90 100 110 120
pF1KB6 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES
50 60 70 80 90 100
130 140 150
pF1KB6 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
:::::::::::::::::::::::::::::::::::::::
XP_005 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
110 120 130 140
>>NP_036407 (OMIM: 605507,614204) interleukin-36 recepto (155 aa)
initn: 410 init1: 242 opt: 414 Z-score: 573.5 bits: 112.3 E(85289): 3.3e-25
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (20-157:9-153)
10 20 30 40 50
pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP---
::. : :..::.::::.:: :.. .: :.:.:::
NP_036 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRW
10 20 30 40
60 70 80 90 100 110
pF1KB6 ----IEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSG
. : ..::..::..:::: :.: : :: ::: .: . :..: :.: : : :
NP_036 LDASLSP--VILGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMG
50 60 70 80 90 100
120 130 140 150
pF1KB6 PTTSFESAACPGWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
:.:::::: :::::::. :::::: ::..:..: . .: ::::.
NP_036 LTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
110 120 130 140 150
>>NP_775262 (OMIM: 605507,614204) interleukin-36 recepto (155 aa)
initn: 410 init1: 242 opt: 414 Z-score: 573.5 bits: 112.3 E(85289): 3.3e-25
Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (20-157:9-153)
10 20 30 40 50
pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP---
::. : :..::.::::.:: :.. .: :.:.:::
NP_775 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRW
10 20 30 40
60 70 80 90 100 110
pF1KB6 ----IEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSG
. : ..::..::..:::: :.: : :: ::: .: . :..: :.: : : :
NP_775 LDASLSP--VILGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMG
50 60 70 80 90 100
120 130 140 150
pF1KB6 PTTSFESAACPGWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE
:.:::::: :::::::. :::::: ::..:..: . .: ::::.
NP_775 LTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
110 120 130 140 150
>>NP_775184 (OMIM: 615296) interleukin-1 family member 1 (152 aa)
initn: 322 init1: 260 opt: 322 Z-score: 447.9 bits: 89.0 E(85289): 3.3e-18
Smith-Waterman score: 322; 42.3% identity (68.6% similar) in 137 aa overlap (26-157:16-150)
10 20 30 40 50 60
pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP
.::..: :..::..: . : ::: ..: .
NP_775 MCSLPMARYYIIKYADQKALYTRDGQLLVGDPVADNCC-AEKICILPNRG
10 20 30 40
70 80 90 100 110
pF1KB6 HA-----LFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPT
: .::::.::. ::.::.. . :::: ::: .: .. .. ::.:..:.:: .
NP_775 LARTKVPIFLGIQGGSRCLACVETEEGPSLQLEDVNIEELYKGGEEATRFTFFQSSSGSA
50 60 70 80 90 100
120 130 140 150
pF1KB6 TSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE
.:.:: :::::: : .:::.::. .: :::::..
NP_775 FRLEAAAWPGWFLCGPAEPQQPVQLTK-ESEPSARTKFYFEQSW
110 120 130 140 150
159 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:35:29 2016 done: Sat Nov 5 07:35:29 2016
Total Scan time: 4.730 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]