Result of FASTA (omim) for
pF1KB6825
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6825, 165 aa
1>>>pF1KB6825 165 - 165 aa - 165 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7122+/-0.000263; mu= 16.4298+/- 0.017
mean_var=68.5292+/-13.969, 0's: 0 Z-trim(119.4): 18 B-trim: 63 in 1/49
Lambda= 0.154930
statistics sampled from 33385 (33403) to 33385 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.392), width: 16
Scan time: 4.910
The best scores are: opt bits E(85289)
NP_036242 (OMIM: 604332) cysteine-rich hydrophobic ( 165) 1160 267.1 8.8e-72
NP_001034929 (OMIM: 300922) cysteine-rich hydropho ( 224) 941 218.3 6e-57
XP_011532684 (OMIM: 604332) PREDICTED: cysteine-ri ( 131) 777 181.5 4.4e-46
NP_001287813 (OMIM: 300922) cysteine-rich hydropho ( 204) 721 169.1 3.6e-42
XP_016885072 (OMIM: 300922) PREDICTED: cysteine-ri ( 123) 716 167.8 5.3e-42
XP_016885071 (OMIM: 300922) PREDICTED: cysteine-ri ( 172) 596 141.1 8.1e-34
XP_006714100 (OMIM: 604332) PREDICTED: cysteine-ri ( 137) 539 128.3 4.7e-30
XP_016885073 (OMIM: 300922) PREDICTED: cysteine-ri ( 119) 234 60.0 1.4e-09
>>NP_036242 (OMIM: 604332) cysteine-rich hydrophobic dom (165 aa)
initn: 1160 init1: 1160 opt: 1160 Z-score: 1409.7 bits: 267.1 E(85289): 8.8e-72
Smith-Waterman score: 1160; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165)
10 20 30 40 50 60
pF1KB6 MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLE
70 80 90 100 110 120
130 140 150 160
pF1KB6 WENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD
:::::::::::::::::::::::::::::::::::::::::::::
NP_036 WENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD
130 140 150 160
>>NP_001034929 (OMIM: 300922) cysteine-rich hydrophobic (224 aa)
initn: 970 init1: 923 opt: 941 Z-score: 1143.4 bits: 218.3 E(85289): 6e-57
Smith-Waterman score: 941; 78.0% identity (91.1% similar) in 168 aa overlap (5-165:57-224)
10 20
pF1KB6 MADFDEIYEEEEDEERA-------LEEQLLKYSP
.: ::::.::.: ::.: .:.:
NP_001 TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAP
30 40 50 60 70 80
30 40 50 60 70 80
pF1KB6 DPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLL
:::.:::.::.:::::::::..:::: :::::::::::.::.:::.:::: :::::.:::
NP_001 DPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLL
90 100 110 120 130 140
90 100 110 120 130 140
pF1KB6 CGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMM
:::::::::::::.::::::.:::::::.::.::::::::::: :::.:.::::::.:::
NP_001 CGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCETSNMM
150 160 170 180 190 200
150 160
pF1KB6 EYVILIEFLPKTPIFRPD
::::::::::: ::::::
NP_001 EYVILIEFLPKYPIFRPD
210 220
>>XP_011532684 (OMIM: 604332) PREDICTED: cysteine-rich h (131 aa)
initn: 774 init1: 774 opt: 777 Z-score: 948.3 bits: 181.5 E(85289): 4.4e-46
Smith-Waterman score: 777; 92.4% identity (97.5% similar) in 119 aa overlap (1-119:1-119)
10 20 30 40 50 60
pF1KB6 MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLE
:::::::::::::::::::::::::::::::::::::::::::::::::: ......
XP_011 PEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRITFALQNIFS
70 80 90 100 110 120
130 140 150 160
pF1KB6 WENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD
XP_011 SLDPQLILSLL
130
>>NP_001287813 (OMIM: 300922) cysteine-rich hydrophobic (204 aa)
initn: 935 init1: 703 opt: 721 Z-score: 878.1 bits: 169.1 E(85289): 3.6e-42
Smith-Waterman score: 768; 68.5% identity (79.8% similar) in 168 aa overlap (5-165:57-204)
10 20
pF1KB6 MADFDEIYEEEEDEERA-------LEEQLLKYSP
.: ::::.::.: ::.: .:.:
NP_001 TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAP
30 40 50 60 70 80
30 40 50 60 70 80
pF1KB6 DPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLL
:::.:::.::.:::::::::..:::: :::::::::::.::.:::.:::: :::::.:::
NP_001 DPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLL
90 100 110 120 130 140
90 100 110 120 130 140
pF1KB6 CGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMM
:::::::::::::.::::::.:::::::.::.::::::::::
NP_001 CGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHK------------------
150 160 170 180
150 160
pF1KB6 EYVILIEFLPKTPIFRPD
::::::::: ::::::
NP_001 --VILIEFLPKYPIFRPD
190 200
>>XP_016885072 (OMIM: 300922) PREDICTED: cysteine-rich h (123 aa)
initn: 716 init1: 716 opt: 716 Z-score: 875.0 bits: 167.8 E(85289): 5.3e-42
Smith-Waterman score: 716; 86.2% identity (97.2% similar) in 109 aa overlap (57-165:15-123)
30 40 50 60 70 80
pF1KB6 PDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWL
:.:::::::.::.:::.:::: :::::.::
XP_016 MDRGKGEKKLNIAVGEVAPEEFKTSIGRVNACLKKALPVNVKWL
10 20 30 40
90 100 110 120 130 140
pF1KB6 LCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNM
::::::::::::::.::::::.:::::::.::.::::::::::: :::.:.::::::.::
XP_016 LCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCETSNM
50 60 70 80 90 100
150 160
pF1KB6 MEYVILIEFLPKTPIFRPD
:::::::::::: ::::::
XP_016 MEYVILIEFLPKYPIFRPD
110 120
>>XP_016885071 (OMIM: 300922) PREDICTED: cysteine-rich h (172 aa)
initn: 625 init1: 578 opt: 596 Z-score: 728.1 bits: 141.1 E(85289): 8.1e-34
Smith-Waterman score: 596; 73.5% identity (88.5% similar) in 113 aa overlap (5-110:57-169)
10 20
pF1KB6 MADFDEIYEEEEDEERA-------LEEQLLKYSP
.: ::::.::.: ::.: .:.:
XP_016 TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAP
30 40 50 60 70 80
30 40 50 60 70 80
pF1KB6 DPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLL
:::.:::.::.:::::::::..:::: :::::::::::.::.:::.:::: :::::.:::
XP_016 DPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLL
90 100 110 120 130 140
90 100 110 120 130 140
pF1KB6 CGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMM
:::::::::::::.::::::.::
XP_016 CGCLCCCCTLGCSLWPVICLNKRVWT
150 160 170
>>XP_006714100 (OMIM: 604332) PREDICTED: cysteine-rich h (137 aa)
initn: 557 init1: 539 opt: 539 Z-score: 660.6 bits: 128.3 E(85289): 4.7e-30
Smith-Waterman score: 852; 83.0% identity (83.0% similar) in 165 aa overlap (1-165:1-137)
10 20 30 40 50 60
pF1KB6 MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLE
:::::::::::::::::::::: ::::::::::
XP_006 PEEFKASINRVNSCLKKNLPVN----------------------------TRRSIEKLLE
70 80 90
130 140 150 160
pF1KB6 WENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD
:::::::::::::::::::::::::::::::::::::::::::::
XP_006 WENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD
100 110 120 130
>>XP_016885073 (OMIM: 300922) PREDICTED: cysteine-rich h (119 aa)
initn: 280 init1: 216 opt: 234 Z-score: 292.9 bits: 60.0 E(85289): 1.4e-09
Smith-Waterman score: 234; 62.3% identity (80.3% similar) in 61 aa overlap (5-58:57-117)
10 20
pF1KB6 MADFDEIYEEEEDEERA-------LEEQLLKYSP
.: ::::.::.: ::.: .:.:
XP_016 TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAP
30 40 50 60 70 80
30 40 50 60 70 80
pF1KB6 DPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLL
:::.:::.::.:::::::::..:::: ::::
XP_016 DPVLVRGAGHITVFGLSNKFDTEFPSVLTGKKF
90 100 110
90 100 110 120 130 140
pF1KB6 CGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMM
165 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 00:03:58 2016 done: Sat Nov 5 00:03:59 2016
Total Scan time: 4.910 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]