Result of FASTA (omim) for
pF1KB6811
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6811, 160 aa
1>>>pF1KB6811 160 - 160 aa - 160 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8045+/-0.000328; mu= 14.0490+/- 0.020
mean_var=50.5951+/-10.063, 0's: 0 Z-trim(114.0): 16 B-trim: 216 in 1/51
Lambda= 0.180310
statistics sampled from 23656 (23668) to 23656 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.278), width: 16
Scan time: 5.290
The best scores are: opt bits E(85289)
NP_056490 (OMIM: 604948) growth arrest and DNA dam ( 160) 1051 280.7 6.8e-76
XP_016882311 (OMIM: 604948) PREDICTED: growth arre ( 176) 791 213.1 1.7e-55
NP_001915 (OMIM: 126335) growth arrest and DNA dam ( 165) 607 165.2 4.1e-41
NP_006696 (OMIM: 604949) growth arrest and DNA dam ( 159) 578 157.7 7.4e-39
NP_001186670 (OMIM: 126335) growth arrest and DNA ( 131) 466 128.5 3.7e-30
XP_011516465 (OMIM: 604949) PREDICTED: growth arre ( 125) 435 120.4 9.5e-28
NP_001186671 (OMIM: 126335) growth arrest and DNA ( 60) 141 43.8 5.3e-05
>>NP_056490 (OMIM: 604948) growth arrest and DNA damage- (160 aa)
initn: 1051 init1: 1051 opt: 1051 Z-score: 1483.5 bits: 280.7 E(85289): 6.8e-76
Smith-Waterman score: 1051; 100.0% identity (100.0% similar) in 160 aa overlap (1-160:1-160)
10 20 30 40 50 60
pF1KB6 MTLEELVACDNAAQKMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLCLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MTLEELVACDNAAQKMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLCLLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 IDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDLHCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDLHCL
70 80 90 100 110 120
130 140 150 160
pF1KB6 LVTNPHTDAWKSHGLVEVASYCEESRGNNQWVPYISLQER
::::::::::::::::::::::::::::::::::::::::
NP_056 LVTNPHTDAWKSHGLVEVASYCEESRGNNQWVPYISLQER
130 140 150 160
>>XP_016882311 (OMIM: 604948) PREDICTED: growth arrest a (176 aa)
initn: 808 init1: 791 opt: 791 Z-score: 1117.4 bits: 213.1 E(85289): 1.7e-55
Smith-Waterman score: 791; 94.0% identity (96.2% similar) in 133 aa overlap (1-133:1-133)
10 20 30 40 50 60
pF1KB6 MTLEELVACDNAAQKMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLCLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTLEELVACDNAAQKMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLCLLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 IDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDLHCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDLHCL
70 80 90 100 110 120
130 140 150 160
pF1KB6 LVTNPHTDAWKSHGLVEVASYCEESRGNNQWVPYISLQER
::: ...: :
XP_016 LVTVSRASALPRHARAPGPVFVNKVGLTGPAQLSAQPRLACPVGSRAGASSPRKLF
130 140 150 160 170
>>NP_001915 (OMIM: 126335) growth arrest and DNA damage- (165 aa)
initn: 616 init1: 413 opt: 607 Z-score: 859.1 bits: 165.2 E(85289): 4.1e-41
Smith-Waterman score: 607; 55.8% identity (78.8% similar) in 165 aa overlap (1-160:1-165)
10 20 30 40 50 60
pF1KB6 MTLEELVACDNAAQKMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLCLLA
:::::. : .. ...:. : :.::.: : : .::::::.:::.:::::.:::::::
NP_001 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLA
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 IDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLL-----GEPAETQGTTEAR
::... :.::::::::::.:::.:::::.:::. :::.:: . :: ..:. .
NP_001 ADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPP
70 80 90 100 110 120
120 130 140 150 160
pF1KB6 DLHCLLVTNPHTDAWKSHGLVEVASYCEESRGNNQWVPYISLQER
::::.::::::.. ::. .: .. .:.::: .:::: :.: ::
NP_001 DLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
130 140 150 160
>>NP_006696 (OMIM: 604949) growth arrest and DNA damage- (159 aa)
initn: 581 init1: 389 opt: 578 Z-score: 818.6 bits: 157.7 E(85289): 7.4e-39
Smith-Waterman score: 578; 55.6% identity (80.9% similar) in 162 aa overlap (1-159:1-159)
10 20 30 40 50
pF1KB6 MTLEELVACDNAAQ---KMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLC
:::::. . :.. . .:: . :..:::..:::: ::.:::::::..:::::.:..:
NP_006 MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 LLAIDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDL
.:: ::.: ::::::::::::.:::.:::.::::. .:::: ..: .: :. ::
NP_006 VLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGA-GEEAGAP--GDL
70 80 90 100 110
120 130 140 150 160
pF1KB6 HCLLVTNPHTDAWKSHGLVEVASYCEESRGNNQWVPYISLQER
::.:..::. ::::. .: ... .:::::. :.::: :.: :
NP_006 HCILISNPNEDAWKDPALEKLSLFCEESRSVNDWVPSITLPE
120 130 140 150
>>NP_001186670 (OMIM: 126335) growth arrest and DNA dama (131 aa)
initn: 494 init1: 272 opt: 466 Z-score: 662.5 bits: 128.5 E(85289): 3.7e-30
Smith-Waterman score: 466; 57.8% identity (80.2% similar) in 116 aa overlap (50-160:16-131)
20 30 40 50 60 70
pF1KB6 TAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLCLLAIDEEEEDDIALQIHFTLIQ
:::.::::::: ::... :.::::::::::
NP_001 MTLEEFSAGEQKTESDPDNVVLCLLAADEDDDRDVALQIHFTLIQ
10 20 30 40
80 90 100 110 120 130
pF1KB6 SFCCDNDINIVRVSGMQRLAQLL-----GEPAETQGTTEARDLHCLLVTNPHTDAWKSHG
.:::.:::::.:::. :::.:: . :: ..:. . ::::.::::::.. ::. .
NP_001 AFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPA
50 60 70 80 90 100
140 150 160
pF1KB6 LVEVASYCEESRGNNQWVPYISLQER
: .. .:.::: .:::: :.: ::
NP_001 LSQLICFCRESRYMDQWVPVINLPER
110 120 130
>>XP_011516465 (OMIM: 604949) PREDICTED: growth arrest a (125 aa)
initn: 461 init1: 266 opt: 435 Z-score: 619.2 bits: 120.4 E(85289): 9.5e-28
Smith-Waterman score: 435; 57.3% identity (81.8% similar) in 110 aa overlap (50-159:19-125)
20 30 40 50 60 70
pF1KB6 TAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLCLLAIDEEEEDDIALQIHFTLIQ
:::.:..:.:: ::.: ::::::::::::
XP_011 MTLEEVRGQDTVPESTARDPDNVTFCVLAAGEEDEGDIALQIHFTLIQ
10 20 30 40
80 90 100 110 120 130
pF1KB6 SFCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDLHCLLVTNPHTDAWKSHGLVEVA
.:::.:::.::::. .:::: ..: .: :. ::::.:..::. ::::. .: ...
XP_011 AFCCENDIDIVRVGDVQRLAAIVGA-GEEAGAPG--DLHCILISNPNEDAWKDPALEKLS
50 60 70 80 90 100
140 150 160
pF1KB6 SYCEESRGNNQWVPYISLQER
.:::::. :.::: :.: :
XP_011 LFCEESRSVNDWVPSITLPE
110 120
>>NP_001186671 (OMIM: 126335) growth arrest and DNA dama (60 aa)
initn: 141 init1: 141 opt: 141 Z-score: 210.8 bits: 43.8 E(85289): 5.3e-05
Smith-Waterman score: 141; 51.0% identity (75.5% similar) in 49 aa overlap (1-49:1-49)
10 20 30 40 50 60
pF1KB6 MTLEELVACDNAAQKMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLCLLA
:::::. : .. ...:. : :.::.: : : .::::::.:::.::
NP_001 MTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVIHIHLNGRILP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 IDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDLHCL
160 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:32:30 2016 done: Fri Nov 4 14:32:31 2016
Total Scan time: 5.290 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]