FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6803, 159 aa
  1>>>pF1KB6803 159 - 159 aa - 159 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.0115+/-0.000308; mu= 12.9208+/- 0.019
 mean_var=54.0582+/-10.725, 0's: 0 Z-trim(115.4): 13  B-trim: 0 in 0/50
 Lambda= 0.174439
 statistics sampled from 25815 (25826) to 25815 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.303), width:  16
 Scan time:  4.830

The best scores are:                                      opt bits E(85289)
NP_006696 (OMIM: 604949) growth arrest and DNA dam ( 159) 1062 274.8 4.1e-74
XP_011516465 (OMIM: 604949) PREDICTED: growth arre ( 125)  736 192.7 1.6e-49
NP_001915 (OMIM: 126335) growth arrest and DNA dam ( 165)  583 154.3 8.2e-38
NP_056490 (OMIM: 604948) growth arrest and DNA dam ( 160)  578 153.0 1.9e-37
NP_001186670 (OMIM: 126335) growth arrest and DNA  ( 131)  459 123.0 1.7e-28
XP_016882311 (OMIM: 604948) PREDICTED: growth arre ( 176)  437 117.5 9.9e-27
NP_001186671 (OMIM: 126335) growth arrest and DNA  (  60)  124 38.6   0.002


>>NP_006696 (OMIM: 604949) growth arrest and DNA damage-  (159 aa)
 initn: 1062 init1: 1062 opt: 1062  Z-score: 1451.6  bits: 274.8 E(85289): 4.1e-74
Smith-Waterman score: 1062; 100.0% identity (100.0% similar) in 159 aa overlap (1-159:1-159)

               10        20        30        40        50        60
pF1KB6 MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFC
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGAGEEAGAPGDLHCI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGAGEEAGAPGDLHCI
               70        80        90       100       110       120

              130       140       150         
pF1KB6 LISNPNEDAWKDPALEKLSLFCEESRSVNDWVPSITLPE
       :::::::::::::::::::::::::::::::::::::::
NP_006 LISNPNEDAWKDPALEKLSLFCEESRSVNDWVPSITLPE
              130       140       150         

>>XP_011516465 (OMIM: 604949) PREDICTED: growth arrest a  (125 aa)
 initn: 834 init1: 736 opt: 736  Z-score: 1009.9  bits: 192.7 E(85289): 1.6e-49
Smith-Waterman score: 770; 78.6% identity (78.6% similar) in 159 aa overlap (1-159:1-125)

               10        20        30        40        50        60
pF1KB6 MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFC
       ::::::::::::::::::                                  ::::::::
XP_011 MTLEEVRGQDTVPESTAR----------------------------------DPDNVTFC
               10                                          20      

               70        80        90       100       110       120
pF1KB6 VLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGAGEEAGAPGDLHCI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGAGEEAGAPGDLHCI
         30        40        50        60        70        80      

              130       140       150         
pF1KB6 LISNPNEDAWKDPALEKLSLFCEESRSVNDWVPSITLPE
       :::::::::::::::::::::::::::::::::::::::
XP_011 LISNPNEDAWKDPALEKLSLFCEESRSVNDWVPSITLPE
         90       100       110       120     

>>NP_001915 (OMIM: 126335) growth arrest and DNA damage-  (165 aa)
 initn: 375 init1: 375 opt: 583  Z-score: 799.9  bits: 154.3 E(85289): 8.2e-38
Smith-Waterman score: 583; 54.5% identity (77.2% similar) in 167 aa overlap (1-159:1-164)

               10        20        30        40        50        60
pF1KB6 MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFC
       :::::  . .   ..: ::. .: ::.:.: .:  :  .:.::::.::.::::::::..:
NP_001 MTLEEFSAGE---QKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLC
               10           20        30        40        50       

               70        80        90       100               110  
pF1KB6 VLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIV--------GAGEEAG
       .::: :.:. :.::::::::::::::::::.:.::..  ::: ..        .:.: : 
NP_001 LLAADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAE
        60        70        80        90       100       110       

            120       130       140       150          
pF1KB6 APGDLHCILISNPNEDAWKDPALEKLSLFCEESRSVNDWVPSITLPE 
        : ::::.:..::. . :::::: .:  ::.::: ...::: :.::: 
NP_001 QPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER
       120       130       140       150       160     

>>NP_056490 (OMIM: 604948) growth arrest and DNA damage-  (160 aa)
 initn: 581 init1: 389 opt: 578  Z-score: 793.3  bits: 153.0 E(85289): 1.9e-37
Smith-Waterman score: 578; 54.9% identity (80.2% similar) in 162 aa overlap (1-159:1-159)

               10        20        30        40        50        60
pF1KB6 MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFC
       :::::. . :.. .   .:: .  :..:::..::::  ::.:::::::..:::::.:..:
NP_056 MTLEELVACDNAAQ---KMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLC
               10           20        30        40        50       

               70        80        90       100       110          
pF1KB6 VLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGAGEEAGAPG---DL
       .::  ::.: ::::::::::::.:::.:::.::::. .:::: ..:   :. .     ::
NP_056 LLAIDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDL
        60        70        80        90       100       110       

       120       130       140       150          
pF1KB6 HCILISNPNEDAWKDPALEKLSLFCEESRSVNDWVPSITLPE 
       ::.:..::. ::::. .: ... .:::::. :.::: :.: : 
NP_056 HCLLVTNPHTDAWKSHGLVEVASYCEESRGNNQWVPYISLQER
       120       130       140       150       160

>>NP_001186670 (OMIM: 126335) growth arrest and DNA dama  (131 aa)
 initn: 281 init1: 262 opt: 459  Z-score: 632.8  bits: 123.0 E(85289): 1.7e-28
Smith-Waterman score: 459; 57.4% identity (79.1% similar) in 115 aa overlap (53-159:16-130)

             30        40        50        60        70        80  
pF1KB6 GKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFCVLAAGEEDEGDIALQIHFTLIQ
                                     :::::..:.::: :.:. :.::::::::::
NP_001                MTLEEFSAGEQKTESDPDNVVLCLLAADEDDDRDVALQIHFTLIQ
                              10        20        30        40     

             90       100               110       120       130    
pF1KB6 AFCCENDIDIVRVGDVQRLAAIV--------GAGEEAGAPGDLHCILISNPNEDAWKDPA
       ::::::::.:.::..  ::: ..        .:.: :  : ::::.:..::. . :::::
NP_001 AFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPA
          50        60        70        80        90       100     

          140       150          
pF1KB6 LEKLSLFCEESRSVNDWVPSITLPE 
       : .:  ::.::: ...::: :.::: 
NP_001 LSQLICFCRESRYMDQWVPVINLPER
         110       120       130 

>>XP_016882311 (OMIM: 604948) PREDICTED: growth arrest a  (176 aa)
 initn: 440 init1: 389 opt: 437  Z-score: 600.9  bits: 117.5 E(85289): 9.9e-27
Smith-Waterman score: 437; 55.6% identity (80.2% similar) in 126 aa overlap (1-123:1-123)

               10        20        30        40        50        60
pF1KB6 MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFC
       :::::. . :.. .   .:: .  :..:::..::::  ::.:::::::..:::::.:..:
XP_016 MTLEELVACDNAAQ---KMQTVTAAVEELLVAAQRQDRLTVGVYESAKLMNVDPDSVVLC
               10           20        30        40        50       

               70        80        90       100       110          
pF1KB6 VLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGAGEEAGAPG---DL
       .::  ::.: ::::::::::::.:::.:::.::::. .:::: ..:   :. .     ::
XP_016 LLAIDEEEEDDIALQIHFTLIQSFCCDNDINIVRVSGMQRLAQLLGEPAETQGTTEARDL
        60        70        80        90       100       110       

       120       130       140       150                          
pF1KB6 HCILISNPNEDAWKDPALEKLSLFCEESRSVNDWVPSITLPE                 
       ::.:..                                                     
XP_016 HCLLVTVSRASALPRHARAPGPVFVNKVGLTGPAQLSAQPRLACPVGSRAGASSPRKLF
       120       130       140       150       160       170      

>>NP_001186671 (OMIM: 126335) growth arrest and DNA dama  (60 aa)
 initn: 113 init1: 113 opt: 124  Z-score: 182.5  bits: 38.6 E(85289): 0.002
Smith-Waterman score: 124; 48.1% identity (73.1% similar) in 52 aa overlap (1-52:1-49)

               10        20        30        40        50        60
pF1KB6 MTLEEVRGQDTVPESTARMQGAGKALHELLLSAQRQGCLTAGVYESAKVLNVDPDNVTFC
       :::::  . .   ..: ::. .: ::.:.: .:  :  .:.::::.::.:::        
NP_001 MTLEEFSAGE---QKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVIHIHLNGR
               10           20        30        40        50       

               70        80        90       100       110       120
pF1KB6 VLAAGEEDEGDIALQIHFTLIQAFCCENDIDIVRVGDVQRLAAIVGAGEEAGAPGDLHCI
                                                                   
NP_001 ILP                                                         
        60                                                         




159 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 00:08:53 2016 done: Sat Nov  5 00:08:54 2016
 Total Scan time:  4.830 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]