FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6760, 147 aa 1>>>pF1KB6760 147 - 147 aa - 147 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5557+/-0.00027; mu= 16.0308+/- 0.017 mean_var=59.9961+/-11.953, 0's: 0 Z-trim(120.5): 136 B-trim: 614 in 1/54 Lambda= 0.165582 statistics sampled from 35585 (35730) to 35585 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.8), E-opt: 0.2 (0.419), width: 16 Scan time: 4.730 The best scores are: opt bits E(85289) NP_003330 (OMIM: 602962) ubiquitin-conjugating enz ( 147) 987 243.0 1.3e-64 NP_871621 (OMIM: 602963) ubiquitin-conjugating enz ( 148) 982 241.8 3e-64 NP_871616 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 980 241.3 4.1e-64 NP_003331 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 980 241.3 4.1e-64 NP_871618 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 980 241.3 4.1e-64 NP_871617 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 980 241.3 4.1e-64 NP_871620 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 980 241.3 4.1e-64 NP_871619 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 980 241.3 4.1e-64 NP_871615 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 980 241.3 4.1e-64 NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147) 970 238.9 2.2e-63 NP_871622 (OMIM: 602963) ubiquitin-conjugating enz ( 149) 949 233.9 7.1e-62 XP_016865309 (OMIM: 602962) PREDICTED: ubiquitin-c ( 173) 945 233.0 1.5e-61 NP_862821 (OMIM: 602962) ubiquitin-conjugating enz ( 118) 805 199.5 1.3e-51 XP_016864073 (OMIM: 602963) PREDICTED: ubiquitin-c ( 118) 797 197.5 5.1e-51 NP_001287724 (OMIM: 602963) ubiquitin-conjugating ( 118) 797 197.5 5.1e-51 XP_016872098 (OMIM: 602961) PREDICTED: ubiquitin-c ( 110) 718 178.6 2.3e-45 NP_001191809 (OMIM: 602961) ubiquitin-conjugating ( 109) 698 173.9 6.3e-44 NP_006348 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 662 165.5 4e-41 NP_001265484 (OMIM: 604151) ubiquitin-conjugating ( 207) 662 165.5 4e-41 XP_005246301 (OMIM: 604151) PREDICTED: ubiquitin-c ( 207) 662 165.5 4e-41 NP_872619 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 662 165.5 4e-41 NP_001265483 (OMIM: 604151) ubiquitin-conjugating ( 207) 662 165.5 4e-41 NP_003332 (OMIM: 602916) ubiquitin-conjugating enz ( 193) 661 165.2 4.4e-41 NP_689866 (OMIM: 602163) ubiquitin-conjugating enz ( 201) 661 165.2 4.6e-41 XP_005265489 (OMIM: 602163) PREDICTED: ubiquitin-c ( 201) 661 165.2 4.6e-41 NP_001189405 (OMIM: 602916) ubiquitin-conjugating ( 160) 655 163.7 1e-40 NP_872607 (OMIM: 602916) ubiquitin-conjugating enz ( 176) 573 144.2 8.8e-35 XP_005265490 (OMIM: 602163) PREDICTED: ubiquitin-c ( 189) 558 140.6 1.1e-33 XP_005265488 (OMIM: 602916) PREDICTED: ubiquitin-c ( 167) 544 137.2 1e-32 NP_003339 (OMIM: 603679) ubiquitin-conjugating enz ( 152) 458 116.6 1.5e-26 NP_003327 (OMIM: 300860,312180) ubiquitin-conjugat ( 152) 449 114.5 6.5e-26 NP_003328 (OMIM: 179095) ubiquitin-conjugating enz ( 152) 443 113.1 1.8e-25 NP_054895 (OMIM: 610538,616435) ubiquitin-conjugat ( 197) 424 108.6 5e-24 NP_005330 (OMIM: 602846) ubiquitin-conjugating enz ( 200) 413 106.0 3.1e-23 NP_003338 (OMIM: 603721) ubiquitin-conjugating enz ( 154) 410 105.2 4.2e-23 NP_001243284 (OMIM: 603721) ubiquitin-conjugating ( 212) 397 102.2 4.6e-22 NP_001297255 (OMIM: 610538,616435) ubiquitin-conju ( 167) 386 99.5 2.4e-21 NP_001269090 (OMIM: 300860,312180) ubiquitin-conju ( 119) 378 97.5 6.9e-21 NP_055316 (OMIM: 610309) ubiquitin-conjugating enz ( 222) 370 95.8 4.1e-20 NP_004214 (OMIM: 603890) ubiquitin/ISG15-conjugati ( 153) 368 95.2 4.4e-20 NP_001243285 (OMIM: 603721) ubiquitin-conjugating ( 122) 366 94.6 5.1e-20 NP_001104582 (OMIM: 602846) ubiquitin-conjugating ( 157) 359 93.0 2e-19 NP_008950 (OMIM: 605574) ubiquitin-conjugating enz ( 179) 356 92.3 3.6e-19 NP_919237 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 349 90.6 1e-18 NP_919235 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 349 90.6 1e-18 XP_016879129 (OMIM: 601661) PREDICTED: SUMO-conjug ( 158) 349 90.6 1e-18 NP_919236 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 349 90.6 1e-18 NP_003336 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 349 90.6 1e-18 NP_861517 (OMIM: 605574) ubiquitin-conjugating enz ( 140) 328 85.6 3.1e-17 NP_003960 (OMIM: 603173) NEDD8-conjugating enzyme ( 183) 322 84.2 1e-16 >>NP_003330 (OMIM: 602962) ubiquitin-conjugating enzyme (147 aa) initn: 987 init1: 987 opt: 987 Z-score: 1281.0 bits: 243.0 E(85289): 1.3e-64 Smith-Waterman score: 987; 93.2% identity (98.6% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB6 MALKRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDY ::::::.:::.:: :::::::::::::::.:::::::::::::::::::::::::::::: NP_003 MALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLV :::::::::::.::::::::::::::::::::::::::.::::::::::::::::::::: NP_003 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB6 PEIAHTYKADREKYNRLAREWTQKYAM ::::. ::.:::::::.:::::::::: NP_003 PEIARIYKTDREKYNRIAREWTQKYAM 130 140 >>NP_871621 (OMIM: 602963) ubiquitin-conjugating enzyme (148 aa) initn: 982 init1: 982 opt: 982 Z-score: 1274.5 bits: 241.8 E(85289): 3e-64 Smith-Waterman score: 982; 92.5% identity (98.6% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB6 MALKRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDY ::::::.:::.:: :::::::::::::::.:::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLV :::::::::::.::::::::::::::::::::::::::.::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB6 PEIAHTYKADREKYNRLAREWTQKYAM ::::. ::.::.::::::::::.:::: NP_871 PEIARIYKTDRDKYNRLAREWTEKYAML 130 140 >>NP_871616 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 980 init1: 980 opt: 980 Z-score: 1272.0 bits: 241.3 E(85289): 4.1e-64 Smith-Waterman score: 980; 91.8% identity (98.6% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB6 MALKRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDY ::::::.:::.:: :::::::::::::::.:::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLV :::::::::::.::::::::::::::::::::::::::.::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB6 PEIAHTYKADREKYNRLAREWTQKYAM ::::. ::.::.::::..::::::::: NP_871 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_003331 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 980 init1: 980 opt: 980 Z-score: 1272.0 bits: 241.3 E(85289): 4.1e-64 Smith-Waterman score: 980; 91.8% identity (98.6% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB6 MALKRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDY ::::::.:::.:: :::::::::::::::.:::::::::::::::::::::::::::::: NP_003 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLV :::::::::::.::::::::::::::::::::::::::.::::::::::::::::::::: NP_003 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB6 PEIAHTYKADREKYNRLAREWTQKYAM ::::. ::.::.::::..::::::::: NP_003 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_871618 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 980 init1: 980 opt: 980 Z-score: 1272.0 bits: 241.3 E(85289): 4.1e-64 Smith-Waterman score: 980; 91.8% identity (98.6% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB6 MALKRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDY ::::::.:::.:: :::::::::::::::.:::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLV :::::::::::.::::::::::::::::::::::::::.::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB6 PEIAHTYKADREKYNRLAREWTQKYAM ::::. ::.::.::::..::::::::: NP_871 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_871617 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 980 init1: 980 opt: 980 Z-score: 1272.0 bits: 241.3 E(85289): 4.1e-64 Smith-Waterman score: 980; 91.8% identity (98.6% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB6 MALKRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDY ::::::.:::.:: :::::::::::::::.:::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLV :::::::::::.::::::::::::::::::::::::::.::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB6 PEIAHTYKADREKYNRLAREWTQKYAM ::::. ::.::.::::..::::::::: NP_871 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_871620 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 980 init1: 980 opt: 980 Z-score: 1272.0 bits: 241.3 E(85289): 4.1e-64 Smith-Waterman score: 980; 91.8% identity (98.6% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB6 MALKRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDY ::::::.:::.:: :::::::::::::::.:::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLV :::::::::::.::::::::::::::::::::::::::.::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB6 PEIAHTYKADREKYNRLAREWTQKYAM ::::. ::.::.::::..::::::::: NP_871 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_871619 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 980 init1: 980 opt: 980 Z-score: 1272.0 bits: 241.3 E(85289): 4.1e-64 Smith-Waterman score: 980; 91.8% identity (98.6% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB6 MALKRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDY ::::::.:::.:: :::::::::::::::.:::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLV :::::::::::.::::::::::::::::::::::::::.::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB6 PEIAHTYKADREKYNRLAREWTQKYAM ::::. ::.::.::::..::::::::: NP_871 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_871615 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa) initn: 980 init1: 980 opt: 980 Z-score: 1272.0 bits: 241.3 E(85289): 4.1e-64 Smith-Waterman score: 980; 91.8% identity (98.6% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB6 MALKRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDY ::::::.:::.:: :::::::::::::::.:::::::::::::::::::::::::::::: NP_871 MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLV :::::::::::.::::::::::::::::::::::::::.::::::::::::::::::::: NP_871 PFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB6 PEIAHTYKADREKYNRLAREWTQKYAM ::::. ::.::.::::..::::::::: NP_871 PEIARIYKTDRDKYNRISREWTQKYAM 130 140 >>NP_003329 (OMIM: 602961) ubiquitin-conjugating enzyme (147 aa) initn: 970 init1: 970 opt: 970 Z-score: 1259.0 bits: 238.9 E(85289): 2.2e-63 Smith-Waterman score: 970; 91.8% identity (97.3% similar) in 147 aa overlap (1-147:1-147) 10 20 30 40 50 60 pF1KB6 MALKRIQKELTDLQRDPPAQCSAGPVGDDLFHWQATIMGPNDSPYQGGVFFLTIHFPTDY ::::::::::.::::::::.:::::::::::::::::::: :: :::::::::.:::::: NP_003 MALKRIQKELSDLQRDPPAHCSAGPVGDDLFHWQATIMGPPDSAYQGGVFFLTVHFPTDY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PFKPPKVAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLV ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 PFKPPKIAFTTKIYHPNINSNGSICLDILRSQWSPALTVSKVLLSICSLLCDPNPDDPLV 70 80 90 100 110 120 130 140 pF1KB6 PEIAHTYKADREKYNRLAREWTQKYAM :.::. ::.:.::::: :::::::::: NP_003 PDIAQIYKSDKEKYNRHAREWTQKYAM 130 140 147 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:01:03 2016 done: Sat Nov 5 04:01:03 2016 Total Scan time: 4.730 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]