FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6738, 140 aa
  1>>>pF1KB6738 140 - 140 aa - 140 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9107+/-0.000337; mu= 12.6202+/- 0.021
 mean_var=54.1410+/-10.995, 0's: 0 Z-trim(113.8): 23  B-trim: 491 in 1/55
 Lambda= 0.174305
 statistics sampled from 23258 (23273) to 23258 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.666), E-opt: 0.2 (0.273), width:  16
 Scan time:  4.900

The best scores are:                                      opt bits E(85289)
NP_005013 (OMIM: 176610,614808) profilin-1 [Homo s ( 140)  930 241.6 3.2e-64
XP_016880250 (OMIM: 176610,614808) PREDICTED: prof ( 181)  720 188.8 3.2e-48
NP_002619 (OMIM: 176590) profilin-2 isoform b [Hom ( 140)  616 162.6 1.9e-40
NP_444252 (OMIM: 176590) profilin-2 isoform a [Hom ( 140)  605 159.8 1.3e-39
NP_001025057 (OMIM: 612812) profilin-3 [Homo sapie ( 137)  400 108.3 4.2e-24


>>NP_005013 (OMIM: 176610,614808) profilin-1 [Homo sapie  (140 aa)
 initn: 930 init1: 930 opt: 930  Z-score: 1273.9  bits: 241.6 E(85289): 3.2e-64
Smith-Waterman score: 930; 100.0% identity (100.0% similar) in 140 aa overlap (1-140:1-140)

               10        20        30        40        50        60
pF1KB6 MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVH
               70        80        90       100       110       120

              130       140
pF1KB6 GGLINKKCYEMASHLRRSQY
       ::::::::::::::::::::
NP_005 GGLINKKCYEMASHLRRSQY
              130       140

>>XP_016880250 (OMIM: 176610,614808) PREDICTED: profilin  (181 aa)
 initn: 738 init1: 720 opt: 720  Z-score: 986.8  bits: 188.8 E(85289): 3.2e-48
Smith-Waterman score: 720; 97.3% identity (98.2% similar) in 112 aa overlap (1-112:1-112)

               10        20        30        40        50        60
pF1KB6 MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVH
       ::::::::::::::::::::::::::::::::::::::::::::::::.  :        
XP_016 VNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKSEFLSLTLPLAP
               70        80        90       100       110       120

              130       140                                        
pF1KB6 GGLINKKCYEMASHLRRSQY                                        
                                                                   
XP_016 RSLMYRLLVILRVLFCVIPQHEGSQTSIVFLVCWMLEHGIVPPFCLSSSSCNSKLLNCIT
              130       140       150       160       170       180

>>NP_002619 (OMIM: 176590) profilin-2 isoform b [Homo sa  (140 aa)
 initn: 616 init1: 616 opt: 616  Z-score: 847.2  bits: 162.6 E(85289): 1.9e-40
Smith-Waterman score: 616; 63.0% identity (84.8% similar) in 138 aa overlap (1-138:1-138)

               10        20        30        40        50        60
pF1KB6 MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFY
       ::::..:.:::: :: ::.:::::: :.  ::::. : .: .::: :. ..::::: .:.
NP_002 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVH
       .::::::..:::::::::  ::. .::.:::: :: ::.::.: .. ..::..:::::::
NP_002 TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRALVIVMGKEGVH
               70        80        90       100       110       120

              130       140
pF1KB6 GGLINKKCYEMASHLRRSQY
       :: .::: ::.: .::::  
NP_002 GGTLNKKAYELALYLRRSDV
              130       140

>>NP_444252 (OMIM: 176590) profilin-2 isoform a [Homo sa  (140 aa)
 initn: 632 init1: 605 opt: 605  Z-score: 832.2  bits: 159.8 E(85289): 1.3e-39
Smith-Waterman score: 605; 61.4% identity (83.6% similar) in 140 aa overlap (1-140:1-140)

               10        20        30        40        50        60
pF1KB6 MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFY
       ::::..:.:::: :: ::.:::::: :.  ::::. : .: .::: :. ..::::: .:.
NP_444 MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVH
       .::::::..:::::::::  ::. .::.:::: :: ::.::.: .. ..::..:::::::
NP_444 TNGLTLGAKKCSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVH
               70        80        90       100       110       120

              130       140
pF1KB6 GGLINKKCYEMASHLRRSQY
       :: .::: : ::..:: : .
NP_444 GGGLNKKAYSMAKYLRDSGF
              130       140

>>NP_001025057 (OMIM: 612812) profilin-3 [Homo sapiens]   (137 aa)
 initn: 401 init1: 300 opt: 400  Z-score: 553.8  bits: 108.3 E(85289): 4.2e-24
Smith-Waterman score: 400; 44.1% identity (70.6% similar) in 136 aa overlap (1-136:1-133)

               10        20        30        40        50        60
pF1KB6 MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFY
       :. :..::. .. :   .:.::::. :.  :::. ::  .. :.: :::::.: :: .: 
NP_001 MGDWKVYISAVLRDQRIDDVAIVGHADNSCVWASRPGGLLAAISPQEVGVLTGPDRHTFL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 VNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVH
         ::..::..: :::: :: .:.  .: :::   :  .  : : .. ..:..:::..:::
NP_001 QAGLSVGGRRCCVIRDHLLAEGDGVLDARTK---GLDARAVCVGRAPRALLVLMGRRGVH
               70        80        90          100       110       

              130       140
pF1KB6 GGLINKKCYEMASHLRRSQY
       ::..::  .:.   ::    
NP_001 GGILNKTVHELIRGLRMQGA
       120       130       




140 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 23:43:09 2016 done: Fri Nov  4 23:43:09 2016
 Total Scan time:  4.900 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]