FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6733, 95 aa 1>>>pF1KB6733 95 - 95 aa - 95 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3677+/-0.000295; mu= 8.2606+/- 0.019 mean_var=56.2499+/-11.274, 0's: 0 Z-trim(116.0): 10 B-trim: 0 in 0/52 Lambda= 0.171007 statistics sampled from 26822 (26831) to 26822 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.315), width: 16 Scan time: 3.440 The best scores are: opt bits E(85289) NP_008868 (OMIM: 603042) small ubiquitin-related m ( 95) 636 164.5 2.4e-41 NP_008867 (OMIM: 602231) small ubiquitin-related m ( 103) 599 155.4 1.4e-38 NP_001002255 (OMIM: 600320,608829) small ubiquitin ( 95) 533 139.1 1.1e-33 NP_001005849 (OMIM: 603042) small ubiquitin-relate ( 71) 339 91.2 2.1e-19 NP_001005781 (OMIM: 601912,613705) small ubiquitin ( 101) 291 79.4 1e-15 NP_003343 (OMIM: 601912,613705) small ubiquitin-re ( 101) 291 79.4 1e-15 NP_001273345 (OMIM: 602231) small ubiquitin-relate ( 141) 291 79.4 1.4e-15 NP_001005782 (OMIM: 601912,613705) small ubiquitin ( 76) 254 70.2 4.5e-13 NP_116204 (OMIM: 614525) NFATC2-interacting protei ( 419) 169 49.4 4.4e-06 >>NP_008868 (OMIM: 603042) small ubiquitin-related modif (95 aa) initn: 636 init1: 636 opt: 636 Z-score: 863.4 bits: 164.5 E(85289): 2.4e-41 Smith-Waterman score: 636; 100.0% identity (100.0% similar) in 95 aa overlap (1-95:1-95) 10 20 30 40 50 60 pF1KB6 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRF 10 20 30 40 50 60 70 80 90 pF1KB6 RFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY ::::::::::::::::::::::::::::::::::: NP_008 RFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 70 80 90 >>NP_008867 (OMIM: 602231) small ubiquitin-related modif (103 aa) initn: 537 init1: 537 opt: 599 Z-score: 813.5 bits: 155.4 E(85289): 1.4e-38 Smith-Waterman score: 599; 96.8% identity (98.9% similar) in 94 aa overlap (1-94:1-93) 10 20 30 40 50 60 pF1KB6 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRF :..::::::::::: ::::::::::::::::::::::::::::::::::::::::::::: NP_008 MSEEKPKEGVKTEN-DHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRF 10 20 30 40 50 70 80 90 pF1KB6 RFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY :::::::::::::::::::::::::::::::::: NP_008 RFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVPESSLAGHSF 60 70 80 90 100 >>NP_001002255 (OMIM: 600320,608829) small ubiquitin-rel (95 aa) initn: 533 init1: 533 opt: 533 Z-score: 726.1 bits: 139.1 E(85289): 1.1e-33 Smith-Waterman score: 533; 85.3% identity (92.6% similar) in 95 aa overlap (1-95:1-95) 10 20 30 40 50 60 pF1KB6 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRF ::.::: : ::::::.::::::::::::::::::::.:::::::::::: .:::..:::: NP_001 MANEKPTEEVKTENNNHINLKVAGQDGSVVQFKIKRQTPLSKLMKAYCEPRGLSVKQIRF 10 20 30 40 50 60 70 80 90 pF1KB6 RFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY :: ::::. :: ::::::::::::::::: ::::: NP_001 RFGGQPISGTDKPAQLEMEDEDTIDVFQQPTGGVY 70 80 90 >>NP_001005849 (OMIM: 603042) small ubiquitin-related mo (71 aa) initn: 346 init1: 339 opt: 339 Z-score: 469.5 bits: 91.2 E(85289): 2.1e-19 Smith-Waterman score: 413; 74.7% identity (74.7% similar) in 95 aa overlap (1-95:1-71) 10 20 30 40 50 60 pF1KB6 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRF ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQ--------- 10 20 30 40 50 70 80 90 pF1KB6 RFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY :::::::::::::::::::: NP_001 ---------------LEMEDEDTIDVFQQQTGGVY 60 70 >>NP_001005781 (OMIM: 601912,613705) small ubiquitin-rel (101 aa) initn: 286 init1: 286 opt: 291 Z-score: 403.0 bits: 79.4 E(85289): 1e-15 Smith-Waterman score: 291; 45.4% identity (78.4% similar) in 97 aa overlap (1-93:1-97) 10 20 30 40 50 pF1KB6 MADEKPKEGVKT----ENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMR :.:.. : ... .....:.::: :::.: ..::.: : :.:: ..::.:::. : NP_001 MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMN 10 20 30 40 50 60 60 70 80 90 pF1KB6 QIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY ..:: :.:: : .. :: .: ::.::.:.:.:.:::: NP_001 SLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV 70 80 90 100 >>NP_003343 (OMIM: 601912,613705) small ubiquitin-relate (101 aa) initn: 286 init1: 286 opt: 291 Z-score: 403.0 bits: 79.4 E(85289): 1e-15 Smith-Waterman score: 291; 45.4% identity (78.4% similar) in 97 aa overlap (1-93:1-97) 10 20 30 40 50 pF1KB6 MADEKPKEGVKT----ENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMR :.:.. : ... .....:.::: :::.: ..::.: : :.:: ..::.:::. : NP_003 MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMN 10 20 30 40 50 60 60 70 80 90 pF1KB6 QIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY ..:: :.:: : .. :: .: ::.::.:.:.:.:::: NP_003 SLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV 70 80 90 100 >>NP_001273345 (OMIM: 602231) small ubiquitin-related mo (141 aa) initn: 291 init1: 291 opt: 291 Z-score: 400.6 bits: 79.4 E(85289): 1.4e-15 Smith-Waterman score: 491; 69.3% identity (69.3% similar) in 127 aa overlap (6-94:6-131) 10 20 30 40 50 pF1KB6 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQ--------- ::::::::: :::::::::::::::::::::::::::::::::::: NP_001 MSEEKPKEGVKTEN-DHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQVRHLAPPQS 10 20 30 40 50 60 70 80 pF1KB6 -----------------------------GLSMRQIRFRFDGQPINETDTPAQLEMEDED ::::::::::::::::::::::::::::::: NP_001 LPVCALVLCVPGIPRARASRGWTQMQLPEGLSMRQIRFRFDGQPINETDTPAQLEMEDED 60 70 80 90 100 110 90 pF1KB6 TIDVFQQQTGGVY :::::::::::: NP_001 TIDVFQQQTGGVPESSLAGHSF 120 130 140 >>NP_001005782 (OMIM: 601912,613705) small ubiquitin-rel (76 aa) initn: 254 init1: 254 opt: 254 Z-score: 355.7 bits: 70.2 E(85289): 4.5e-13 Smith-Waterman score: 254; 50.0% identity (80.6% similar) in 72 aa overlap (22-93:1-72) 10 20 30 40 50 60 pF1KB6 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRF .. ::.: ..::.: : :.:: ..::.:::. : ..:: NP_001 MSDQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRF 10 20 30 70 80 90 pF1KB6 RFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY :.:: : .. :: .: ::.::.:.:.:.:::: NP_001 LFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV 40 50 60 70 >>NP_116204 (OMIM: 614525) NFATC2-interacting protein [H (419 aa) initn: 156 init1: 132 opt: 169 Z-score: 230.1 bits: 49.4 E(85289): 4.4e-06 Smith-Waterman score: 169; 36.4% identity (74.0% similar) in 77 aa overlap (12-87:342-418) 10 20 30 40 pF1KB6 MADEKPKEGVKTENNDHINLKVAGQDG-SVVQFKIKRHTPL ::......:.: :.. .... ...: .:: NP_116 ELSPTATPRTLKLGVADIIDCVVLTSSPEATETSQQLQLRVQGKEKHQTLEVSLSRDSPL 320 330 340 350 360 370 50 60 70 80 90 pF1KB6 SKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY . ::. : : .::: :.. : ::: .. . ::.: ::. : :.:. NP_116 KTLMSHYEEAMGLSGRKLSFFFDGTKLSGRELPADLGMESGDLIEVWG 380 390 400 410 95 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:35:20 2016 done: Fri Nov 4 15:35:21 2016 Total Scan time: 3.440 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]