FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6712, 132 aa
  1>>>pF1KB6712 132 - 132 aa - 132 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8048+/-0.000285; mu= 10.3438+/- 0.018
 mean_var=119.7148+/-23.654, 0's: 0 Z-trim(122.9): 18  B-trim: 885 in 1/53
 Lambda= 0.117220
 statistics sampled from 41668 (41703) to 41668 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.829), E-opt: 0.2 (0.489), width:  16
 Scan time:  4.610

The best scores are:                                      opt bits E(85289)
NP_003055 (OMIM: 107285) antileukoproteinase precu ( 132) 1010 180.2 8.4e-46
NP_002629 (OMIM: 182257) elafin preproprotein [Hom ( 117)  210 44.9 4.1e-05
NP_543145 (OMIM: 609872) WAP four-disulfide core d ( 111)  207 44.3 5.6e-05
NP_065131 (OMIM: 609031) eppin isoform 1 precursor ( 133)  178 39.5  0.0019


>>NP_003055 (OMIM: 107285) antileukoproteinase precursor  (132 aa)
 initn: 1010 init1: 1010 opt: 1010  Z-score: 943.3  bits: 180.2 E(85289): 8.4e-46
Smith-Waterman score: 1010; 100.0% identity (100.0% similar) in 132 aa overlap (1-132:1-132)

               10        20        30        40        50        60
pF1KB6 MKSSGLFPFLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQCLRYKKPECQSDWQCPGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MKSSGLFPFLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQCLRYKKPECQSDWQCPGK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCMG
               70        80        90       100       110       120

              130  
pF1KB6 MCGKSCVSPVKA
       ::::::::::::
NP_003 MCGKSCVSPVKA
              130  

>>NP_002629 (OMIM: 182257) elafin preproprotein [Homo sa  (117 aa)
 initn: 340 init1: 192 opt: 210  Z-score: 212.8  bits: 44.9 E(85289): 4.1e-05
Smith-Waterman score: 216; 33.8% identity (52.3% similar) in 130 aa overlap (1-129:1-116)

               10        20        30        40        50        60
pF1KB6 MKSSGLFPFLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQCLRYKKPECQSDWQCPGK
       :..:...  .:.:  :::.  :.        .::  : :. . .. . :   .:   : :
NP_002 MRASSFLIVVVFLIAGTLVLEAAV-------TGV--PVKGQDTVKGRVPFNGQD---PVK
               10        20                 30        40           

                70        80        90       100       110         
pF1KB6 KRCC-PDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCM
        .        .:  .::  :  :  :::.::.   .: :::::: :  : .:    ::: 
NP_002 GQVSVKGQDKVKAQEPVKGPVST--KPGSCPIILIRCAMLNPPNRCLKDTDCPGIKKCCE
       50        60        70          80        90       100      

     120       130  
pF1KB6 GMCGKSCVSPVKA
       : :: .:  :   
NP_002 GSCGMACFVPQ  
        110         

>>NP_543145 (OMIM: 609872) WAP four-disulfide core domai  (111 aa)
 initn: 178 init1: 163 opt: 207  Z-score: 210.3  bits: 44.3 E(85289): 5.6e-05
Smith-Waterman score: 207; 41.6% identity (72.7% similar) in 77 aa overlap (1-76:1-74)

               10        20        30         40        50         
pF1KB6 MKSSGLFPFLVLLALGTLAPWAVEGSGKSF-KAGVCPPKKSAQCLRYKKPECQSDWQCPG
       : ::... ..: :.: ::.  ::::  ... ::::::   ...:..   :.:..: .: :
NP_543 MGSSSFLVLMVSLVLVTLV--AVEGVKEGIEKAGVCPAD-NVRCFKSDPPQCHTDQDCLG
               10          20        30         40        50       

      60        70        80        90       100       110         
pF1KB6 KKRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCM
       ...::   ::.::. ::                                           
NP_543 ERKCCYLHCGFKCVIPVKELEEGGNKDEDVSRPYPEPGWEAKCPGSSSTRCPQK      
        60        70        80        90       100       110       

>>NP_065131 (OMIM: 609031) eppin isoform 1 precursor [Ho  (133 aa)
 initn: 177 init1: 133 opt: 178  Z-score: 182.9  bits: 39.5 E(85289): 0.0019
Smith-Waterman score: 178; 30.3% identity (50.8% similar) in 132 aa overlap (1-122:1-127)

               10        20          30        40        50        
pF1KB6 MKSSGLFPFLVLLALGTLAPWAVEGSGKS--FKAGVCPPKKSAQCLRYKKPECQSDWQCP
       : ::::. .:::..:  ::   :.: : .  .    :: :   .:   ..  : .: :: 
NP_065 MGSSGLLSLLVLFVL--LA--NVQGPGLTDWLFPRRCP-KIREECEFQERDVCTKDRQCQ
               10            20        30         40        50     

       60        70        80        90       100         110      
pF1KB6 GKKRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEM--DGQCK----
        .:.::  .:: ::::  .      .. : : . . .  . .  : : :   : :.    
NP_065 DNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNN
          60        70        80        90       100       110     

              120       130  
pF1KB6 --RDLKCCMGMCGKSCVSPVKA
         ..   :.. :          
NP_065 NFQSKANCLNTCKNKRFP    
         120       130       




132 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 23:30:42 2016 done: Fri Nov  4 23:30:43 2016
 Total Scan time:  4.610 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]